{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T00:12:03Z","timestamp":1783210323268,"version":"3.54.6"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:00:00Z","timestamp":1721260800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004434","name":"Universit\u00e0 degli Studi di Firenze","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004434","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurochir"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Frontal lobe epilepsy is pharmacoresistant in 30% of cases, constituting 10\u201320% of epilepsy surgeries. For cases of no lesional epilepsy (negative MRI), frontal lobectomy is a crucial treatment, historically involving Frontal Anatomical Lobectomy (AFL) with a 33.3% complication risk and 55.7% seizure control.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We describe Frontal Functional Lobectomy (FFL), in which the boundaries are defined on the patient's functional cortico-subcortical areas, recognized with advanced intraoperative technologies such as tractography and navigated transcranial magnetic stimulation (nTMS).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The FFL allows for a broader resection with a lower rate of postoperative complications than the AFL.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00701-024-06176-x","type":"journal-article","created":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T00:02:19Z","timestamp":1721260939000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Functional frontal lobectomy in the surgical treatment of pharmacoresistant frontal lobe epilepsy: how I do it"],"prefix":"10.1007","volume":"166","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5866-5350","authenticated-orcid":false,"given":"Francesca","family":"Battista","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Muscas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Della Puppa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,18]]},"reference":[{"key":"6176_CR1","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.3171\/2012.1.Jns111620","volume":"116","author":"DJ Englot","year":"2012","unstructured":"Englot DJ, Wang DD, Rolston JD, Shih TT, Chang EF (2012) Rates and predictors of long-term seizure freedom after frontal lobe epilepsy surgery: a systematic review and meta-analysis. J Neurosurg 116:1042\u20131048. https:\/\/doi.org\/10.3171\/2012.1.Jns111620","journal-title":"J Neurosurg"},{"key":"6176_CR2","doi-asserted-by":"publisher","first-page":"17","DOI":"10.2176\/nmc.oa.2018-0286","volume":"60","author":"S Hirata","year":"2020","unstructured":"Hirata S, Morino M, Nakae S, Matsumoto T (2020) Surgical technique and outcome of extensive frontal lobectomy for treatment of intracable non-lesional frontal lobe epilepsy. Neurol Med Chir 60:17\u201325. https:\/\/doi.org\/10.2176\/nmc.oa.2018-0286","journal-title":"Neurol Med Chir"},{"key":"6176_CR3","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1093\/brain\/awl364","volume":"130","author":"LE Jeha","year":"2007","unstructured":"Jeha LE, Najm I, Bingaman W, Dinner D, Widdess-Walsh P, L\u00fcders H (2007) Surgical outcome and prognostic factors of frontal lobe epilepsy surgery. Brain 130:574\u2013584. https:\/\/doi.org\/10.1093\/brain\/awl364","journal-title":"Brain"},{"key":"6176_CR4","doi-asserted-by":"publisher","first-page":"2316","DOI":"10.1093\/brain\/awh246","volume":"127","author":"R Matsumoto","year":"2004","unstructured":"Matsumoto R, Nair DR, LaPresto E, Najm I, Bingaman W, Shibasaki H, L\u00fcders HO (2004) Functional connectivity in the human language system: a cortico-cortical evoked potential study. Brain 127:2316\u20132330. https:\/\/doi.org\/10.1093\/brain\/awh246","journal-title":"Brain"},{"key":"6176_CR5","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1227\/00006123-199302000-00011","volume":"32","author":"M Taniguchi","year":"1993","unstructured":"Taniguchi M, Cedzich C, Taniguchi M, Cedzich C, Schramm J (1993) Modification of cortical stimulation for motor evoked potentials under general anesthesia: technical description. Neurosurgery 32:219\u2013226","journal-title":"Neurosurgery"},{"key":"6176_CR6","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1016\/j.wneu.2016.10.090","volume":"98","author":"HT Wen","year":"2017","unstructured":"Wen HT, Da R\u00f3z LM, Rhoton AL Jr, Castro LH, Teixeira MJ (2017) Frontal lobe decortication (Frontal Lobectomy with Ventricular Preservation) in epilepsy-part 1: anatomic landmarks and surgical technique. World Neurosurg 98:347\u2013364. https:\/\/doi.org\/10.1016\/j.wneu.2016.10.090","journal-title":"World Neurosurg"}],"container-title":["Acta Neurochirurgica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-024-06176-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00701-024-06176-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00701-024-06176-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:03:42Z","timestamp":1740171822000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00701-024-06176-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,18]]},"references-count":6,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["6176"],"URL":"https:\/\/doi.org\/10.1007\/s00701-024-06176-x","relation":{},"ISSN":["0942-0940"],"issn-type":[{"value":"0942-0940","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,18]]},"assertion":[{"value":"18 March 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 June 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 July 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 July 2024","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The correct family name is Della Puppa and not Puppa.  The html has been corrected.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}],"article-number":"299"}}