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Here, we tested the hypothesis that equivalents to B-waves can be detected and quantified in a noninvasively measured electric capacitance signal termed W.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We measured ICP and W in a cohort of 15 patients with suspected diagnosis of NPH or spontaneous intracranial hypotension during infusion testing, identifying B-waves in both signals by wave-template matching in the time domain.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>We found very strong correlation between the duration of B-waves in ICP and W (R<jats:sup>2<\/jats:sup>\u2009=\u20090.86, <jats:italic>p<\/jats:italic>\u2009&lt;\u200910<jats:sup>\u20136<\/jats:sup>),\u00a0and weak correlation between the average B-wave amplitudes in ICP and W (R = 0.34, p = 0.02).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>The concurrent presence of B-waves in the signals suggests that vasogenic activity of cerebral autoregulation is reflected in W.\u00a0The weaker correlation of amplitudes may be attributed to W being an indirect measure of cranial volume composition, whereas ICP is a measure of pressure, with the two linked by the non-linear craniospinal pressure-volume relation that varies between patients. Analysis of the noninvasively acquired W signal should be evaluated as a triage tool for patients with NPH and other disorders characterized by reduced compliance.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00701-025-06461-3","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T07:02:36Z","timestamp":1741244556000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["B-waves in noninvasive capacitance signal correlate with B-waves in ICP"],"prefix":"10.1007","volume":"167","author":[{"given":"Andreas","family":"Spiegelberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Boraschi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramy","family":"Amirah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mukesch","family":"Shah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Krismer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Beck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vartan","family":"Kurtcuoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,3,6]]},"reference":[{"key":"6461_CR1","unstructured":"\u00c5gren-Wilsson A (2005) On the pathophysiology of idiopathic adult hydrocephalus syndrome\u00a0- energy metabolism, protein patterns, and intracranial pressure, MD thesis no. 955. 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