{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:11:44Z","timestamp":1790611904667,"version":"4.1.0"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:00:00Z","timestamp":1758758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"University of Stavanger & Stavanger University Hospital"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurochir"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Introduction<\/jats:title>\n            <jats:p>MIS pedicle screw placement is a novel technique for the management of unstable injuries of the cervical spine. This study aims to evaluate the feasibility of MIS pedicle screw placement and to compare perioperative, postoperative and radiological outcomes between MIS and conventional open approaches.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>This single-centre cohort study included patients with unstable injuries of the cervical spine treated with open approaches for pedicle or lateral mass screw fixation or MIS approaches for pedicle screw fixation. Perioperative and postoperative variables were compared. All screw positions were classified according to the Bredow classification.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Twenty patients with unstable injuries of the cervical spine were included, 10 undergoing conventional open posterior fixation (87 screws) and 10 undergoing MIS cervical pedicle screw fixation (48 screws). In the MIS group, significantly fewer vertebrae were instrumented (2.4 vs. 4.5; <jats:italic>p<\/jats:italic>\u2009=\u20090.008) and significantly fewer screws placed (4.8 vs. 8.7; p\u2009=\u20090.009). Operative time was significantly shorter in patients operated with MIS approach (183 vs. 132\u00a0min; p\u2009=\u20090.020). Also, there was a significant reduction in blood loss per surgery in patients operated with a MIS approach compared to an open approach (145 vs. 891\u00a0ml; p\u2009=\u20090.002). Out of 87 pedicle and lateral mass screws placed with an open approach 99% were classified as Bredow grade 1 or 2. All 48 screws placed with a MIS approach were rated as Bredow grade 1 or 2.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>This feasibility study provides preliminary evidence that surgery with MIS approach with navigated pedicle screws may be associated with reduced length of surgery and intraoperative blood loss compared to open surgery. Radiological evaluation of screw placement showed a good positioning with both open and minimally invasive approach. The results highlight the need for further investigation in larger, controlled trials to more rigorously evaluate the potential benefits and risks\u00a0of this approach.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00701-025-06680-8","type":"journal-article","created":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T05:47:10Z","timestamp":1758779230000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Minimally invasive pedicle screw placement with image-guided navigation in cervical spine injuries"],"prefix":"10.1007","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7007-5719","authenticated-orcid":false,"given":"Clemens","family":"Weber","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kjell","family":"Akre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Avellan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maziar","family":"Behbahani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Werner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,25]]},"reference":[{"issue":"1","key":"6680_CR1","doi-asserted-by":"publisher","first-page":"323","DOI":"10.21037\/jss.2019.11.01","volume":"6","author":"RK Badiee","year":"2020","unstructured":"Badiee RK, Mayer R, Pennicooke B, Chou D, Mummaneni PV, Tan LA (2020) Complications following posterior cervical decompression and fusion: a review of incidence, risk factors, and prevention strategies. 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Consent to participate has been waived.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Tis study was approved by the Stavanger University Hospital data protection officer as a quality assurance project (eProtokoll ID: 4993) according to The Norwegian Healthcare Personnel Act. Consent to participate has been waived.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethics and consent to participate declarations"}},{"value":"CW and DW have received speaker and consult honoraria from Brainlab AG, Munich, Germany.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"254"}}