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This study aimed to analyze the association between patients\u2019 home medications and the risk of cerebral infarction and poor functional outcomes after SAH.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective analysis included 995 patients with aneurysmal SAH treated at our clinic between January 2003 and June 2016. Various demographic and clinical baseline characteristics were examined, with a particular focus on regular use of home medications. The study endpoints were the occurrence of early (within 72\u00a0h post-SAH) and DCI-related infarcts (&gt;\u200972\u00a0h) in follow-up computed tomography scans, as well as the functional disability at six months, defined as a modified Rankin Scale\u2009&gt;\u20092.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no association between the occurrence of early infarcts and patients\u2019 regular medications. In contrast, individuals with calcium channel blockers (CCB) use (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200993) showed a higher rate of DCI (32.6% vs 19.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005) and 6-months functional disability (57.8% vs 46.8%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.048). In multivariable analysis, CCB use was independently associated with the risk of DCI (adjusted odds ratio [aOR]\u2009=\u20094.05;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) and functional disability after six months (aOR\u2009=\u20092.73;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Regular CCB use was independently associated with an increased risk of DCI and functional disability at six months. These findings warrant cautious interpretation and further validation in prospective studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00701-025-06730-1","type":"journal-article","created":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T19:06:48Z","timestamp":1764184008000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The impact of home medications on the risk of delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage"],"prefix":"10.1007","volume":"167","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9297-9030","authenticated-orcid":false,"given":"Pikria","family":"Ketelauri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meltem","family":"G\u00fcm\u00fcs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanah Hadice","family":"Karadachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Michel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aigerim","family":"Togyzbayeva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laur\u00e8l","family":"Rauschenbach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nika","family":"Guberina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelius","family":"Deuschl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marvin Darkwah","family":"Oppong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahya","family":"Ahmadipour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Dammann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich","family":"Sure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramazan","family":"Jabbarli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,26]]},"reference":[{"issue":"1","key":"6730_CR1","volume":"5","author":"MH Abbasi","year":"2025","unstructured":"Abbasi MH et al (2025) Angiotensin inhibition reduces the risk of subarachnoid hemorrhage in patients with hypertension. 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