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Surgical resection is the standard treatment. However, owing to their adherence to critical structures, complete resection is often not possible. The role of stereotactic radiosurgery (SRS) in the management of RGNT remains inconclusive. We present a case of tissue-confirmed RGNT successfully treated with SRS.\u00a0A 24-year-old woman presented with diplopia and dysequilibrium and was subsequently diagnosed with a fourth ventricular tumor. Subtotal resection was performed at another hospital, and a tissue-based diagnosis of RGNT was made. After a multidisciplinary discussion and following the patient\u2019s willingness, single-session SRS was prescribed at a marginal dose of 12\u00a0Gy. During the subsequent 66-month follow-up period, radiologic regression of the tumor with corresponding resolution of symptoms was noted. She remained neurologically intact at her last official visit.\u00a0The treatment paradigm for residual RGNT remains elusive due to its scarcity and varied presentation. We have presented our preliminary experience with a residual RGNT that was managed with SRS, attaining long-term freedom from tumor progression. SRS may be a safe, effective, and durable treatment modality for patients with RGNT.<\/jats:p>","DOI":"10.1007\/s00701-026-06773-y","type":"journal-article","created":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T19:53:32Z","timestamp":1770062012000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Stereotactic radiosurgery for residual rosette-forming glioneuronal tumor: a case report and literature review"],"prefix":"10.1007","volume":"168","author":[{"given":"Yung-Lin","family":"Hsiao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huai-Che","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chun-Fu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng-Chia","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kang-Du","family":"Liou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tzu-Chiang","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,2]]},"reference":[{"key":"6773_CR1","doi-asserted-by":"publisher","first-page":"64","DOI":"10.5414\/NP300682","volume":"34","author":"K Allinson","year":"2015","unstructured":"Allinson K, O\u2019Donovan DG, Jena R, Cross JJ, Santarius TS (2015) Rosette-forming glioneuronal tumor with dissemination throughout the ventricular system: a case report. 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