{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T09:02:47Z","timestamp":1774429367052,"version":"3.50.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T00:00:00Z","timestamp":1774396800000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Acta Neurochir"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Neurosurgical patients frequently require intensive postoperative care. However, data on the factors influencing their outcomes in low-resource environments are limited. This study aimed to identify the predictors of mortality among neurosurgical patients admitted to the Surgical Intensive Care Unit at the Tikur Anbessa Specialized Hospital, Ethiopia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A retrospective cohort study was conducted between January 1, 2024, and January 1, 2025. All neurosurgical patients admitted to the surgical Intensive Care during the study period were reviewed. Patient outcomes were categorized as death during Intensive Care Unit stay or discharge or transfer with clinical improvement. Multivariate logistic regression analysis was performed using SPSS version 27, and variables with\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05 were considered statistically significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 140 neurosurgical patients were included, with an overall ICU mortality rate of 23% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200932). Emergency surgery (AOR\u2009=\u20097.4; 95% CI: 1.26\u201313.97;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027), intraoperative blood loss\u2009&gt;\u20091000\u00a0mL (AOR\u2009=\u20094.0; 95% CI: 1.96\u20135.29;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.044), lack of continuous postoperative monitoring (AOR\u2009=\u20093.5; 95% CI: 1.93\u201313.15;\n                      <jats:italic>p\u2009<\/jats:italic>\n                      =\u20090.044), and ICU complications (AOR\u2009=\u20097.8; 95% CI: 1.92\u201313.49;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.004) were independently associated with increased mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>23% Of the neurosurgical patients admitted to the SICU died during the ICU stay. Mortality was independently associated with emergency surgery, significant intraoperative blood loss, lack of continuous postoperative monitoring, and the occurrence of ICU-related complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00701-026-06842-2","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T19:28:59Z","timestamp":1774380539000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mortality and its predictors among neurosurgical patients admitted to the surgical ICU in a resource-limited setting: experience from Ethiopia"],"prefix":"10.1007","volume":"168","author":[{"given":"Absera Gebriel","family":"Yohannes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Molla Asnake","family":"Kebede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amira","family":"Shamil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kidus Geabriel","family":"Yohannes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dejen Tekiea","family":"Gebrewahd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turi Abateka","family":"Abadiga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abera","family":"Kuma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selemon Gebrezgabiher","family":"Asgedom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,3,24]]},"reference":[{"issue":"3","key":"6842_CR1","doi-asserted-by":"publisher","first-page":"336","DOI":"10.3126\/jnhrc.v16i3.21434","volume":"16","author":"SP Acharya","year":"2018","unstructured":"Acharya SP, Bhattarai B, Bhattarai A, Pradhan S, Sharma MR (2018) Profile of neurosurgical patients in a tertiary level intensive care unit in Nepal. 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All the listed authors met the authorship criteria and reviewed and approved the final version of the manuscript. This work has not been previously published and is not currently under consideration by any other journal. No specific reporting checklist was used to prepare this manuscript.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval for this study was granted by the Institutional Review Board (IRB) of Addis Ababa University. This study was conducted in accordance with the principles of the Declaration of Helsinki. Strict measures were taken to maintain privacy and confidentiality, ensuring that no personal identifiers including names were recorded.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All participants provided and signed written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for participation"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"82"}}