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We aimed to identify health related quality of life (HRQoL) issues in this favorable functional outcome group compared to a sex and age matched general population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We have analyzed data from 634 Swedish aSAH patients from a national prospective study ranging between 2014 and 2018.\u00a0One year after ictus, functional outcome was analyzed using Glasgow Outcome Scale Extended (GOSE) and HRQoL assessed by Euro-quality of life\u20145 dimensions\u20143 levels (EQ-5D-3L). Favorable GOSE (5\u20138) were found in 471 patients. Age- and sex-matched populations were created by published data from a cross-sectional cohort of 32,597 people living in Stockholm County in 2006. Odds ratios (ORs) for rating a specific EQ-5D-3L level were calculated for each domain. Significance was set at \u03b1\u2009=\u20090.001.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Patients reported less mobility problems than the matched general population (9.6% vs 14.7%; OR 0.62\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). However, with usual activities significantly more difficulties with moderate, (\n                      <jats:italic>24.0% vs 10.9%;<\/jats:italic>\n                      OR 2.58,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) and any problems (27.0% vs 12.5%; OR 2.58,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.001) were reported. More issues with extreme anxiety\/depression were also reported ((5.3% vs 2.8%; OR 1.94;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). Unfavorable GOSE patients were doing worse than the matched population in all levels and dimensions measured (Online Resource 1, 2, 3 and 4).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Although patients with favorable functional outcome report good or better mobility compared to their age and sex matched general population, they have significantly more issues with usual activities a year after aSAH more extreme issues with anxiety\/depression were also reported To our knowledge, this is the first time EQ-5D-3L data is compared in a national group of aSAH patients with favorable functional outcome to a sex and age matched general population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00701-026-07059-z","type":"journal-article","created":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:33:37Z","timestamp":1792143217000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Targeting health-related quality of life issues not found with functional outcome measures a year after aneurysm subarachnoid hemorrhage in a Swedish national cohort"],"prefix":"10.1007","volume":"168","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3354-4146","authenticated-orcid":false,"given":"Helena","family":"Aineskog","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brynd\u00eds","family":"Baldvinsd\u00f3ttir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola G.","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asgeir S.","family":"Jakola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Kronvall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth Ronne","family":"Engstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Klurfan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Alpkvist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikael","family":"Svensson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Hillman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Lindvall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,16]]},"reference":[{"key":"7059_CR1","unstructured":"Swedish Council on Health Technology Assessment (2008) Moderately elevated blood pressure: a systematic review [Internet]. 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World Neurosurg 190:e513\u2013e524. https:\/\/doi.org\/10.1016\/j.wneu.2024.07.164","journal-title":"World Neurosurg"},{"key":"7059_CR3","doi-asserted-by":"publisher","first-page":"e519","DOI":"10.1161\/STROKEAHA.110.581975","volume":"41","author":"T Al-Khindi","year":"2010","unstructured":"Al-Khindi T, Macdonald RL, Schweizer TA (2010) Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage. 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