{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T01:31:42Z","timestamp":1790472702240,"version":"4.1.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2010,10,8]],"date-time":"2010-10-08T00:00:00Z","timestamp":1286496000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2010,10,8]],"date-time":"2010-10-08T00:00:00Z","timestamp":1286496000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1007\/s00702-010-0477-5","type":"journal-article","created":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T04:24:15Z","timestamp":1286425455000},"page":"47-60","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["RETRACTED ARTICLE: Expression of heat shock protein (HSP 72\u00a0kDa) during acute methamphetamine intoxication depends on brain hyperthermia: neurotoxicity or neuroprotection?"],"prefix":"10.1007","volume":"118","author":[{"given":"Eugene A.","family":"Kiyatkin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hari S.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,10,8]]},"reference":[{"key":"477_CR1","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1379\/CSC-42.1","volume":"9","author":"S Ammon-Treiber","year":"2004","unstructured":"Ammon-Treiber S, Grecksch G, Strumm R, Reichert U, Tischmeyer H, Reichenauer A, Hollt V (2004) Rapid, transient, and dose-dependent expression of Hsp70 messenger RNA in the rat brain after morphine treatment. Cell Stress Chaperones 9:182\u2013197","journal-title":"Cell Stress Chaperones"},{"key":"477_CR3","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1046\/j.1471-4159.2000.740641.x","volume":"74","author":"DA Bechtold","year":"2000","unstructured":"Bechtold DA, Rush SJ, Brown IR (2000) Localization of the heat-shock protein Hsp70 to the synapse following hyperthermic stress in the brain. J Neurochem 74:641\u2013646","journal-title":"J Neurochem"},{"key":"477_CR4","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1111\/j.1749-6632.1999.tb08009.x","volume":"890","author":"JF Bowyer","year":"1999","unstructured":"Bowyer JF, Davies DL (1999) Changes in mRNA levels for heat-shock\/stress proteins (Hsp) and a secretory vesicle associated cysteine-string protein (Csp1) after amphetamine (AMPH) exposure. Ann NY Acad Sci 890:314\u2013329","journal-title":"Ann NY Acad Sci"},{"key":"477_CR100","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1002\/syn.20324","volume":"60","author":"JF Bowyer","year":"2006","unstructured":"Bowyer JF, Ali S (2006) High doses of methamphetamine that cause disruption of the blood-brain barrier in limbic regions produce extensive neuronal degeneration in mouse hippocampus. Synapse 60:521\u2013532","journal-title":"Synapse"},{"key":"477_CR5","first-page":"86","volume":"1","author":"PL Brown","year":"2005","unstructured":"Brown PL, Kiyatkin EA (2005) Fatal intra-brain heat accumulation induced by meth-amphetamine at normothermic conditions in rats. Int J Neuroprot Neuroregener 1:86\u201390","journal-title":"Int J Neuroprot Neuroregener"},{"key":"477_CR6","doi-asserted-by":"publisher","first-page":"3924","DOI":"10.1523\/JNEUROSCI.23-09-03924.2003","volume":"23","author":"PL Brown","year":"2003","unstructured":"Brown PL, Wise RA, Kiyatkin EA (2003) Brain hyperthermia is induced by methamphetamine and exacerbated by social interaction. J Neurosci 23:3924\u20133929","journal-title":"J Neurosci"},{"key":"477_CR7","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/0006-8993(95)00044-Q","volume":"675","author":"S Fukudo","year":"1995","unstructured":"Fukudo S, Abe K, Hongo M, Utsumi A, Itoyama Y (1995) Psychophysiological stress induces heat shock cognate protein (HSC070) mRNA in the cerebral cortex and stomach in rats. Brain Res 675:98\u2013102","journal-title":"Brain Res"},{"key":"477_CR8","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0006-8993(93)90602-J","volume":"626","author":"S Goto","year":"1993","unstructured":"Goto S, Korematsu K, Oyama T, Yamada K, Hamada J, Inoue N, Nagahiro S, Ushio Y (1993) Neuronal induction of 72-kDa heat shock protein following methamphetamine-induced hyperthermia in the mouse hippocampus. Brain Res 626:351\u2013356","journal-title":"Brain Res"},{"key":"477_CR9","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1016\/S0079-6123(06)62021-9","volume":"162","author":"M Horowitz","year":"2007","unstructured":"Horowitz M, Robinson SDM (2007) Heat shock proteins and heat shock response during hyperthermia and its modulation by altered physiological conditions. Prog Brain Res 162:433\u2013446","journal-title":"Prog Brain Res"},{"key":"477_CR10","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/S0163-7258(98)00028-X","volume":"80","author":"JG Kiang","year":"1998","unstructured":"Kiang JG, Tsokos GC (1998) Heat shock protein 70\u00a0kDa: molecular biology, biochemistry, and physiology. Pharmacol Ther 80:183\u2013201","journal-title":"Pharmacol Ther"},{"key":"477_CR11","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.brainresrev.2005.04.001","volume":"50","author":"EA Kiyatkin","year":"2005","unstructured":"Kiyatkin EA (2005) Brain hyperthermia as physiological and pathological phenomena. Brain Res Rev 50:27\u201356","journal-title":"Brain Res Rev"},{"key":"477_CR12","doi-asserted-by":"publisher","first-page":"73","DOI":"10.2741\/3608","volume":"15","author":"EA Kiyatkin","year":"2010","unstructured":"Kiyatkin EA (2010) Brain temperature homeostasis: physiological fluctuations and pathological shifts. Front Biosci 15:73\u201392","journal-title":"Front Biosci"},{"key":"477_CR103","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1016\/j.physbeh.2004.08.032","volume":"83","author":"EA Kiyatkin","year":"2004","unstructured":"Kiyatkin EA, Brown PL (2004) Modulation of physiological brain hyperthermia by environmental temperature and impaired blood outflow in rats. Physiol Behav 83:467\u2013474","journal-title":"Physiol Behav"},{"key":"477_CR13","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/S0074-7742(09)88004-5","volume":"88","author":"EA Kiyatkin","year":"2009","unstructured":"Kiyatkin EA, Sharma HS (2009) Acute methamphetamine intoxication: brain hyperthermia, blood\u2013brain barrier, brain edema, and morphological cell abnormalities. Int Rev Neurobiol 88:65\u2013100","journal-title":"Int Rev Neurobiol"},{"key":"477_CR14","doi-asserted-by":"publisher","first-page":"1342","DOI":"10.1111\/j.1460-9568.2007.05741.x","volume":"26","author":"EA Kiyatkin","year":"2007","unstructured":"Kiyatkin EA, Brown PL, Sharma HS (2007) Brain edema and breakdown of the blood\u2013brain barrier during methamphetamine intoxication: critical role of brain temperature. Eur J Neurosci 26:1342\u20131353","journal-title":"Eur J Neurosci"},{"key":"477_CR15","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/S0006-8993(97)00710-5","volume":"771","author":"DI Kuperman","year":"1997","unstructured":"Kuperman DI, Freyadenhoven TE, Schmued LC, Ali SF (1997) Methamphetamine-induced hyperthermia in mice: examination of dopamine depletion and heat-shock protein induction. Brain Res 771:221\u2013227","journal-title":"Brain Res"},{"key":"477_CR16","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1379\/CSC-18R.1","volume":"9","author":"GI Lancaster","year":"2004","unstructured":"Lancaster GI, Moller K, Nielsen B, Secher NH, Febbraio MA, Nybo L (2004) Exercise induces the release of heat shock protein 72 from the human brain in vivo. Cell Stress Chaperones 9:276\u2013280","journal-title":"Cell Stress Chaperones"},{"key":"477_CR17","doi-asserted-by":"publisher","first-page":"2060","DOI":"10.1111\/j.1471-4159.1991.tb03467.x","volume":"56","author":"EK Miller","year":"1991","unstructured":"Miller EK, Raese JD, Morrison-Bogorad M (1991) Expression of heat shock protein 70 and heat shock cognate 70 messenger RNAs in rat cortex and cerebellum after heat shock or amphetamine treatment. J Neurochem 56:2060\u20132071","journal-title":"J Neurochem"},{"key":"477_CR18","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1111\/j.1750-3639.1994.tb00812.x","volume":"4","author":"TS Nowak","year":"1994","unstructured":"Nowak TS, Jecewicz M (1994) The heat shock\/stress response in focal cerebral ischemia. Brain Pathol 4:67\u201376","journal-title":"Brain Pathol"},{"key":"477_CR19","first-page":"R1600","volume":"294","author":"Y Oqura","year":"2008","unstructured":"Oqura Y, Naito H, Akin S, Ischinoseki-Sekine N, Kirosaka M, Kakigi R, Saquiura T, Powers SK, Katamoto S, Damirel HA (2008) Elevation of body temperature is an essential factor for exercise-increased extracellular heat shock protein 72 level in rat plasma. Am J Physiol 294:R1600\u2013R1607","journal-title":"Am J Physiol"},{"key":"477_CR20","volume-title":"The rat brain in stereotaxic coordinates","author":"G Paxinos","year":"1998","unstructured":"Paxinos G, Watson C (1998) The rat brain in stereotaxic coordinates, 4th edn. Academic Press, San Diego","edition":"4"},{"key":"477_CR21","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/0169-328X(94)90193-7","volume":"27","author":"AM Planas","year":"1994","unstructured":"Planas AM, Soriano MA, Ferrer I, Farre ER (1994) Regional expression of inducible heat shock protein-70 mRNA in the rat brain following administration of convulsant drugs. Mol Brain Res 27:127\u2013137","journal-title":"Mol Brain Res"},{"key":"477_CR22","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1379\/1466-1268(1997)002<0162:TMETHI>2.3.CO;2","volume":"2","author":"J-C Plumier","year":"1997","unstructured":"Plumier J-C, Krueger AM, Currie RW, Kontoyiannis D, Kollias G, Pagpulatos GN (1997) Response of transgenic mice expressing the human 70-kDa heat shock protein to cerebral ischemia. Cell Stress Chaperones 2:162\u2013167","journal-title":"Cell Stress Chaperones"},{"key":"477_CR23","doi-asserted-by":"publisher","first-page":"433","DOI":"10.1126\/science.3175665","volume":"242","author":"KT Riabowol","year":"1988","unstructured":"Riabowol KT, Mizzen LA, Welch WJ (1988) Heat shock is lethal to fibroblasts microinjected with antibodies against hsp70. Science 242:433\u2013436","journal-title":"Science"},{"key":"477_CR24","doi-asserted-by":"publisher","first-page":"2667","DOI":"10.1152\/japplphysiol.01173.2001","volume":"92","author":"AA Romanovsky","year":"2002","unstructured":"Romanovsky AA, Ivanov AI, Shimansky YP (2002) Ambient temperature for experiments in rats: a new method for determining the zone of thermal neutrality. J Appl Physiol 92:2667\u20132679","journal-title":"J Appl Physiol"},{"key":"477_CR101","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1161\/01.RES.52.4.367","volume":"52","author":"LB Rowell","year":"1983","unstructured":"Rowell LB (1983) Cardiovascular aspects of human thermoregulation. Circ Res 52:367\u2013379","journal-title":"Circ Res"},{"key":"477_CR102","first-page":"383","volume":"51","author":"HS Sharma","year":"1990","unstructured":"Sharma HS, Cerv\u00f3s-Navarro J (1990) Brain oedema and cellular changes induced by acute heat stress in young rats. Acta Neurochir Suppl (Wein) 51:383\u2013386","journal-title":"Acta Neurochir Suppl (Wein)"},{"key":"477_CR27","doi-asserted-by":"publisher","first-page":"198","DOI":"10.1196\/annals.1369.020","volume":"1074","author":"HS Sharma","year":"2006","unstructured":"Sharma HS, Ali SF (2006) Alterations in blood\u2013brain barrier function by morphine and methamphetamine. Ann NY Acad Sci 1074:198\u2013224","journal-title":"Ann NY Acad Sci"},{"key":"477_CR28","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.jchemneu.2008.08.002","volume":"37","author":"HS Sharma","year":"2009","unstructured":"Sharma HS, Kiyatkin EA (2009) Rapid morphological brain abnormalities during acute methamphetamine intoxication in the rat: an experimental study using light and electreon microscopy. J Chem Neuroanat 37:18\u201332","journal-title":"J Chem Neuroanat"},{"key":"477_CR29","doi-asserted-by":"publisher","first-page":"422","DOI":"10.1007\/BF00228575","volume":"86","author":"HS Sharma","year":"1993","unstructured":"Sharma HS, Olsson Y, Cerv\u00f3s-Navarro J (1993) p-Chlorophenylalanine, a serotonin synthesis inhibitor, reduces the response of glial fibrillary acidic protein induced by trauma to the spinal cord. An immunohistochemical investigation in the rat. Acta Neuropathol 86:422\u2013427","journal-title":"Acta Neuropathol"},{"key":"477_CR30","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1016\/0168-0102(94)00855-A","volume":"21","author":"HS Sharma","year":"1995","unstructured":"Sharma HS, Olsson Y, Westman J (1995) A serotonin synthesis inhibitor, p-chlorophenylalanine reduces the heat shock protein response following trauma to the spinal cord: an immunohistochemical and ultrastructural study in the rat. Neurosci Res 21:241\u2013249","journal-title":"Neurosci Res"},{"key":"477_CR31","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/0168-0102(95)01015-7","volume":"24","author":"HS Sharma","year":"1996","unstructured":"Sharma HS, Westman J, Olsson Y, Alm P (1996) Involvement of nitric oxide in acute spinal cord injury: an immunocytochemical study using light and electron microscopy in the rat. Neurosci Res 24:373\u2013384","journal-title":"Neurosci Res"},{"key":"477_CR32","first-page":"269","volume":"70","author":"HS Sharma","year":"1997","unstructured":"Sharma HS, Westman J, Cerv\u00f3s-Navarro J, Nyberg F (1997) Role of neurochemicals in brain edema and cell changes following hyperthermic brain injury in the rat. Acta Neurochir Suppl 70:269\u2013274","journal-title":"Acta Neurochir Suppl"},{"key":"477_CR33","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1007\/s00702-005-0405-2","volume":"113","author":"HS Sharma","year":"2006","unstructured":"Sharma HS, Gordh T, Wiklund L, Mohanty S, Sj\u00f6quist PO (2006) Spinal cord injury induced heat shock protein expression is reduced by an antioxidant compound H -290\/51. An experimental study using light and electron microscopy in the rat. J Neural Transm 113:521\u2013536","journal-title":"J Neural Transm"},{"key":"477_CR34","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0074-7742(09)88011-2","volume":"88","author":"HS Sharma","year":"2009","unstructured":"Sharma HS, Muresanu D, Sharma A, Patnaik R (2009) Cocaine-induced breakdown of the blood\u2013brain barrier and neurotoxicity. Int Rev Neurobiol 88:297\u2013334","journal-title":"Int Rev Neurobiol"},{"key":"477_CR35","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1111\/j.1749-6632.2009.05330.x","volume":"1199","author":"HS Sharma","year":"2010","unstructured":"Sharma HS, Muresanu D, Sharma A, Zimmermann-Meinzingen S (2010) Cerebrolysin treatment attenuates heat shock protein overexpression in the brain following heat stress: an experimental study using immunohistochemistry at light and electron microscopy in the rat. Ann NY Acad Sci 1199:138\u2013148","journal-title":"Ann NY Acad Sci"},{"key":"477_CR37","doi-asserted-by":"crossref","unstructured":"Stetler RA, Gan Y, Zhang W, Liou AK, Gao Y, Cao G, Chen J (2010) Heat shock proteins: cellular and molecular mechanisms in the CNS. Prog Neurobiol (in press)","DOI":"10.1016\/j.pneurobio.2010.05.002"},{"key":"477_CR38","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1007\/BF00687422","volume":"77","author":"K Vass","year":"1988","unstructured":"Vass K, Welch WJ, Nowak TS (1988) Localization of 70-kD stress protein induction in gerbil after ischemia. Acta Neuropathol 77:128\u2013135","journal-title":"Acta Neuropathol"},{"key":"477_CR39","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1152\/physrev.1992.72.4.1063","volume":"72","author":"WJ Welch","year":"1992","unstructured":"Welch WJ (1992) Mammalian stress response: cell physiology, structure\/function of stress proteins, and implications for medicine and disease. Physiol Rev 72:1063\u20131081","journal-title":"Physiol Rev"},{"key":"477_CR40","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/S0079-6123(08)62038-5","volume":"115","author":"J Westman","year":"1998","unstructured":"Westman J, Sharma HS (1998) Heat shock protein response in the central nervous system following hyperthermia. Prog Brain Res 115:207\u2013239","journal-title":"Prog Brain Res"},{"key":"477_CR41","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/S0006-8993(99)01154-3","volume":"823","author":"X Yu","year":"1999","unstructured":"Yu X, Imam SZ, Newport GD, Slikker W, Ali SF (1999) Ibogaine blocked methamphetamine-induced hyperthermia and induction of heat shock protein in mice. Brain Res 823:213\u2013216","journal-title":"Brain Res"}],"updated-by":[{"DOI":"10.1007\/s00702-025-03072-1","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T00:00:00Z","timestamp":1764979200000}}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-010-0477-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00702-010-0477-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-010-0477-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-010-0477-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T15:07:30Z","timestamp":1785596850000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00702-010-0477-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10,8]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["477"],"URL":"https:\/\/doi.org\/10.1007\/s00702-010-0477-5","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,10,8]]},"assertion":[{"value":"9 August 2010","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 August 2010","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 October 2010","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 December 2025","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article has been retracted. Please see the Retraction Notice for more detail:","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s00702-025-03072-1","URL":"https:\/\/doi.org\/10.1007\/s00702-025-03072-1","order":8,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}}]}}