{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T02:32:10Z","timestamp":1791081130379,"version":"4.1.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T00:00:00Z","timestamp":1355270400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1007\/s00702-012-0933-5","type":"journal-article","created":{"date-parts":[[2012,12,11]],"date-time":"2012-12-11T17:20:36Z","timestamp":1355246436000},"page":"659-664","source":"Crossref","is-referenced-by-count":24,"title":["Imaging impulse control disorders in Parkinson\u2019s disease and their relationship to addiction"],"prefix":"10.1007","volume":"120","author":[{"given":"Nicola J.","family":"Ray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio P.","family":"Strafella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,12,12]]},"reference":[{"issue":"Pt 9","key":"933_CR1","doi-asserted-by":"crossref","first-page":"2396","DOI":"10.1093\/brain\/awp170","volume":"132","author":"B Abler","year":"2009","unstructured":"Abler B, Hahlbrock R, Unrath A, Gr\u00f6n G, Kassubek J (2009) At-risk for pathological gambling: imaging neural reward processing under chronic dopamine agonists. Brain J Neurol 132(Pt 9):2396\u20132402","journal-title":"Brain J Neurol"},{"issue":"2","key":"933_CR2","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1523\/JNEUROSCI.17-02-00851.1997","volume":"17","author":"V Bassareo","year":"1997","unstructured":"Bassareo V, Di Chiara G (1997) Differential influence of associative and nonassociative learning mechanisms on the responsiveness of prefrontal and accumbal dopamine transmission to food stimuli in rats fed ad libitum. J Neurosci 17(2):851\u2013861","journal-title":"J Neurosci"},{"issue":"1","key":"933_CR3","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.bbr.2008.09.027","volume":"199","author":"D Belin","year":"2009","unstructured":"Belin D, Jonkman S, Dickinson A, Robbins TW, Everitt BJ (2009) Parallel and interactive learning processes within the basal ganglia: relevance for the understanding of addiction. Behav Brain Res 199(1):89\u2013102. doi: 10.1016\/j.bbr.2008.09.027","journal-title":"Behav Brain Res"},{"issue":"7","key":"933_CR4","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1177\/014107689608900711","volume":"89","author":"K Blum","year":"1996","unstructured":"Blum K, Sheridan PJ, Wood RC, Braverman ER, Chen TJ, Cull JG, Comings DE (1996) The D2 dopamine receptor gene as a determinant of reward deficiency syndrome. J R Soc Med 89(7):396\u2013400","journal-title":"J R Soc Med"},{"issue":"5991","key":"933_CR5","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1126\/science.1185778","volume":"329","author":"JW Buckholtz","year":"2010","unstructured":"Buckholtz JW, Treadway MT, Cowan RL, Woodward ND, Li R, Ansari MS, Baldwin RM et al (2010) Dopaminergic network differences in human impulsivity. Science 329(5991):532. doi: 10.1126\/science.1185778","journal-title":"Science"},{"issue":"3","key":"933_CR6","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.neuron.2008.12.031","volume":"61","author":"L Clark","year":"2009","unstructured":"Clark L, Lawrence AJ, Astley-Jones F, Gray N (2009) Gambling near-misses enhance motivation to gamble and recruit win-related brain circuitry. Neuron 61(3):481\u2013490. doi: 10.1016\/j.neuron.2008.12.031","journal-title":"Neuron"},{"issue":"1","key":"933_CR7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neubiorev.2005.03.024","volume":"30","author":"R Cools","year":"2006","unstructured":"Cools R (2006) Dopaminergic modulation of cognitive function-implications for L-DOPA treatment in Parkinson\u2019s disease. Neurosci Biobehav Rev 30(1):1\u201323. doi: 10.1016\/j.neubiorev.2005.03.024","journal-title":"Neurosci Biobehav Rev"},{"issue":"20","key":"933_CR8","doi-asserted-by":"crossref","first-page":"5506","DOI":"10.1523\/JNEUROSCI.0601-07.2007","volume":"27","author":"R Cools","year":"2007","unstructured":"Cools R, Sheridan M, Jacobs E, D\u2019Esposito M (2007) Impulsive personality predicts dopamine-dependent changes in frontostriatal activity during component processes of working memory. J Neurosci 27(20):5506\u20135514. doi: 10.1523\/JNEUROSCI.0601-07.2007","journal-title":"J Neurosci"},{"issue":"1\u20132","key":"933_CR9","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0166-4328(02)00286-3","volume":"137","author":"G Chiara Di","year":"2002","unstructured":"Di Chiara G (2002) Nucleus accumbens shell and core dopamine: differential role in behavior and addiction. Behav Brain Res 137(1\u20132):75\u2013114","journal-title":"Behav Brain Res"},{"issue":"1","key":"933_CR10","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.coph.2006.11.003","volume":"7","author":"G Chiara Di","year":"2007","unstructured":"Di Chiara G, Bassareo V (2007) Reward system and addiction: what dopamine does and doesn\u2019t do. Curr Opin Pharmacol 7(1):69\u201376. doi: 10.1016\/j.coph.2006.11.003","journal-title":"Curr Opin Pharmacol"},{"issue":"4","key":"933_CR11","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1097\/01.wco.0000137528.23126.41","volume":"17","author":"AH Evans","year":"2004","unstructured":"Evans AH, Lees AJ (2004) Dopamine dysregulation syndrome in Parkinson\u2019s disease. Curr Opin Neurol 17(4):393\u2013398","journal-title":"Curr Opin Neurol"},{"issue":"5","key":"933_CR12","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1002\/ana.20822","volume":"59","author":"AH Evans","year":"2006","unstructured":"Evans AH, Pavese N, Lawrence AD, Tai YF, Appel S, Doder M, Brooks DJ, Lees AJ, Piccini P (2006) Compulsive drug use linked to sensitized ventral striatal dopamine transmission. Ann Neurol 59(5):852\u2013858","journal-title":"Ann Neurol"},{"issue":"14","key":"933_CR13","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1056\/NEJM198804073181402","volume":"318","author":"SJ Kish","year":"1988","unstructured":"Kish SJ, Shannak K, Hornykiewicz O (1988) Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson\u2019s disease. Pathophysiologic and clinical implications. N Engl J Med 318(14):876\u2013880. doi: 10.1056\/NEJM198804073181402","journal-title":"N Engl J Med"},{"issue":"10","key":"933_CR14","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1176\/appi.ajp.163.10.1806","volume":"163","author":"LM Koran","year":"2006","unstructured":"Koran LM, Faber RJ, Aboujaoude E, Large MD, Serpe RT (2006) Estimated prevalence of compulsive buying behavior in the United States. Am J Psychiatry 163(10):1806\u20131812. doi: 10.1176\/appi.ajp.163.10.1806","journal-title":"Am J Psychiatry"},{"issue":"1","key":"933_CR15","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1007\/s00213-009-1645-x","volume":"207","author":"AJ Lawrence","year":"2009","unstructured":"Lawrence AJ, Luty J, Bogdan NA, Sahakian BJ, Clark L (2009) Impulsivity and response inhibition in alcohol dependence and problem gambling. Psychopharmacology 207(1):163\u2013172. doi: 10.1007\/s00213-009-1645-x","journal-title":"Psychopharmacology"},{"issue":"3\u20134","key":"933_CR16","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s00213-005-0280-4","volume":"184","author":"D Lecca","year":"2006","unstructured":"Lecca D, Cacciapaglia F, Valentini V, Gronli J, Spiga S, Di Chiara G (2006) Preferential increase of extracellular dopamine in the rat nucleus accumbens shell as compared to that in the core during acquisition and maintenance of intravenous nicotine self-administration. Psychopharmacology 184(3\u20134):435\u2013446. doi: 10.1007\/s00213-005-0280-4","journal-title":"Psychopharmacology"},{"issue":"2","key":"933_CR17","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s00213-011-2550-7","volume":"219","author":"RF Leeman","year":"2012","unstructured":"Leeman RF, Potenza MN (2012) Similarities and differences between pathological gambling and substance use disorders: a focus on impulsivity and compulsivity. Psychopharmacology 219(2):469\u2013490. doi: 10.1007\/s00213-011-2550-7","journal-title":"Psychopharmacology"},{"issue":"8","key":"933_CR18","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1038\/sj.npp.1301568","volume":"33","author":"CR Li","year":"2008","unstructured":"Li CR, Huang C, Yan P, Bhagwagar Z, Milivojevic V, Sinha R (2008) Neural correlates of impulse control during stop signal inhibition in cocaine-dependent men. Neuropsychopharmacology 33(8):1798\u20131806. doi: 10.1038\/sj.npp.1301568","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"933_CR19","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1152\/jn.1994.72.2.1024","volume":"72","author":"J Mirenowicz","year":"1994","unstructured":"Mirenowicz J, Schultz W (1994) Importance of unpredictability for reward responses in primate dopamine neurons. J Neurophysiol 72(2):1024\u20131027","journal-title":"J Neurophysiol"},{"issue":"10","key":"933_CR20","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1017\/S0033291711000316","volume":"41","author":"BL Odlaug","year":"2011","unstructured":"Odlaug BL, Chamberlain SR, Kim SW, Schreiber LRN, Grant JE (2011) A neurocognitive comparison of cognitive flexibility and response inhibition in gamblers with varying degrees of clinical severity. Psychol Med 41(10):2111\u20132119. doi: 10.1017\/S0033291711000316","journal-title":"Psychol Med"},{"issue":"Pt 4","key":"933_CR21","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1093\/brain\/awr003","volume":"134","author":"SS O\u2019Sullivan","year":"2011","unstructured":"O\u2019Sullivan SS, Wu K, Politis M, Lawrence AD, Evans AH, Bose SK, Djamshidian A, Lees AJ, Piccini P (2011) Cue-induced striatal dopamine release in Parkinson\u2019s disease-associated impulsive-compulsive behaviours. Brain 134(Pt 4):969\u2013978","journal-title":"Brain"},{"issue":"7","key":"933_CR22","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1212\/01.wnl.0000238401.76928.45","volume":"67","author":"G Pontone","year":"2006","unstructured":"Pontone G, Williams JR, Bassett SS, Marsh L (2006) Clinical features associated with impulse control disorders in Parkinson disease. Neurology 67(7):1258\u20131261. doi: 10.1212\/01.wnl.0000238401.76928.45","journal-title":"Neurology"},{"issue":"1507","key":"933_CR23","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1098\/rstb.2008.0100","volume":"363","author":"MN Potenza","year":"2008","unstructured":"Potenza MN (2008) Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos Trans R Soc Lond B Biol Sci 363(1507):3181\u20133189. doi: 10.1098\/rstb.2008.0100","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"issue":"11","key":"933_CR24","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1176\/appi.ajp.160.11.1990","volume":"160","author":"MN Potenza","year":"2003","unstructured":"Potenza MN, Leung H-C, Blumberg HP, Peterson BS, Fulbright RK, Lacadie CM, Skudlarski P et al (2003) An FMRI Stroop task study of ventromedial prefrontal cortical function in pathological gamblers. Am J Psychiatry 160(11):1990\u20131994","journal-title":"Am J Psychiatry"},{"key":"933_CR25","first-page":"594860","volume":"2011","author":"N Ray","year":"2011","unstructured":"Ray N, Antonelli F, Strafella AP (2011) Imaging impulsivity in Parkinson\u2019s disease and the contribution of the subthalamic nucleus. Parkinson\u2019s disease 2011:594860. doi: 10.4061\/2011\/594860","journal-title":"Parkinson\u2019s disease"},{"key":"933_CR26","author":"N Ray","year":"2012","unstructured":"Ray N, Miyasaki JM, Zurowski M, Ko JH, Cho SS, Pellecchia G, Antonelli F et al (2012) Extrastriatal dopaminergic abnormalities of DA homeostasis in Parkinson\u2019s patients with medication-induced pathological gambling: a [11C] FLB-457 and PET study. Neurobiol Dis. doi: 10.1016\/j.nbd.2012.06.021","journal-title":"Neurobiol Dis"},{"issue":"2","key":"933_CR27","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/nn1378","volume":"8","author":"J Reuter","year":"2005","unstructured":"Reuter J, Raedler T, Rose M, Hand I, Gl\u00e4scher J, B\u00fcchel C (2005) Pathological gambling is linked to reduced activation of the mesolimbic reward system. Nat Neurosci 8(2):147\u2013148. doi: 10.1038\/nn1378","journal-title":"Nat Neurosci"},{"issue":"9","key":"933_CR28","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.2105\/AJPH.89.9.1369","volume":"89","author":"HJ Shaffer","year":"1999","unstructured":"Shaffer HJ, Hall MN, Vander Bilt J (1999) Estimating the prevalence of disordered gambling behavior in the United States and Canada: a research synthesis. Am J Public Health 89(9):1369\u20131376","journal-title":"Am J Public Health"},{"issue":"Pt 5","key":"933_CR29","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1093\/brain\/awp054","volume":"132","author":"TDL Steeves","year":"2009","unstructured":"Steeves TDL, Miyasaki J, Zurowski M, Lang AE, Pellecchia G, van Eimeren T, Rusjan P et al (2009) Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C]raclopride PET study. Brain J Neurol 132(Pt 5):1376\u20131385. doi: 10.1093\/brain\/awp054","journal-title":"Brain J Neurol"},{"issue":"13","key":"933_CR30","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1038\/npp.2009.124","volume":"34","author":"T Eimeren van","year":"2009","unstructured":"van Eimeren T, Ballanger B, Pellecchia G, Miyasaki JM, Lang AE, Strafella AP (2009) Dopamine agonists diminish value sensitivity of the orbitofrontal cortex: a trigger for pathological gambling in Parkinson\u2019s disease? Neuropsychopharmacology 34(13):2758\u20132766. doi: 10.1038\/sj.npp.npp2009124","journal-title":"Neuropsychopharmacology"},{"issue":"19","key":"933_CR31","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1212\/WNL.0b013e3181fc27fa","volume":"75","author":"T Eimeren van","year":"2010","unstructured":"van Eimeren T, Pellecchia G, Cilia R, Ballanger B, Steeves TDL, Houle S, Miyasaki JM et al (2010) Drug-induced deactivation of inhibitory networks predicts pathological gambling in PD. Neurology 75(19):1711\u20131716. doi: 10.1212\/WNL.0b013e3181fc27fa","journal-title":"Neurology"},{"issue":"12","key":"933_CR32","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1176\/appi.ajp.158.12.2015","volume":"158","author":"ND Volkow","year":"2001","unstructured":"Volkow ND, Chang L, Wang GJ, Fowler JS, Ding YS, Sedler M, Logan J et al (2001) Low level of brain dopamine D2 receptors in methamphetamine abusers: association with metabolism in the orbitofrontal cortex. Am J Psychiatry 158(12):2015\u20132021","journal-title":"Am J Psychiatry"},{"issue":"2","key":"933_CR33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/syn.10137","volume":"46","author":"ND Volkow","year":"2002","unstructured":"Volkow ND, Wang G-J, Fowler JS, Thanos PPK, Logan J, Gatley SJ, Gifford A et al (2002) Brain DA D2 receptors predict reinforcing effects of stimulants in humans: replication study. Synapse 46(2):79\u201382. doi: 10.1002\/syn.10137","journal-title":"Synapse"},{"issue":"Suppl 1","key":"933_CR34","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.neuropharm.2004.07.019","volume":"47","author":"Nora D Volkow","year":"2004","unstructured":"Volkow Nora D, Fowler JS, Wang G-J (2004) The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies. Neuropharmacology 47(Suppl 1):3\u201313. doi: 10.1016\/j.neuropharm.2004.07.019","journal-title":"Neuropharmacology"},{"issue":"24","key":"933_CR35","doi-asserted-by":"crossref","first-page":"6583","DOI":"10.1523\/JNEUROSCI.1544-06.2006","volume":"26","author":"Nora D Volkow","year":"2006","unstructured":"Volkow Nora D, Wang G-J, Telang F, Fowler JS, Logan J, Childress A-R, Jayne M et al (2006) Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction. J Neurosci 26(24):6583\u20136588. doi: 10.1523\/JNEUROSCI.1544-06.2006","journal-title":"J Neurosci"},{"issue":"4","key":"933_CR36","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1016\/j.neuroimage.2008.06.002","volume":"42","author":"Nora D Volkow","year":"2008","unstructured":"Volkow Nora D, Wang G-J, Telang F, Fowler JS, Thanos PK, Logan J, Alexoff D et al (2008) Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors. NeuroImage 42(4):1537\u20131543. doi: 10.1016\/j.neuroimage.2008.06.002","journal-title":"NeuroImage"},{"issue":"7","key":"933_CR37","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1212\/01.wnl.0000238503.20816.13","volume":"67","author":"V Voon","year":"2006","unstructured":"Voon V, Hassan K, Zurowski M, de Souza M, Thomsen T, Fox S, Lang AE et al (2006) Prevalence of repetitive and reward-seeking behaviors in Parkinson disease. Neurology 67(7):1254\u20131257. doi: 10.1212\/01.wnl.0000238503.20816.13","journal-title":"Neurology"},{"issue":"1","key":"933_CR38","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.neuron.2009.12.027","volume":"65","author":"Valerie Voon","year":"2010","unstructured":"Voon Valerie, Pessiglione M, Brezing C, Gallea C, Fernandez HH, Dolan RJ, Hallett M (2010) Mechanisms underlying dopamine-mediated reward bias in compulsive behaviors. Neuron 65(1):135\u2013142. doi: 10.1016\/j.neuron.2009.12.027","journal-title":"Neuron"},{"issue":"6","key":"933_CR39","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1002\/ana.22356","volume":"69","author":"Valerie Voon","year":"2011","unstructured":"Voon Valerie, Sohr M, Lang AE, Potenza MN, Siderowf AD, Whetteckey J, Weintraub D et al (2011) Impulse control disorders in Parkinson disease: a multicenter case\u2013control study. Ann Neurol 69(6):986\u2013996. doi: 10.1002\/ana.22356","journal-title":"Ann Neurol"},{"issue":"5","key":"933_CR41","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1001\/archneurol.2010.65","volume":"67","author":"D Weintraub","year":"2010","unstructured":"Weintraub D, Koester J, Potenza MN, Siderowf AD, Stacy M, Voon V, Whetteckey J et al (2010) Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Arch Neurol 67(5):589\u2013595. doi: 10.1001\/archneurol.2010.65","journal-title":"Arch Neurol"},{"issue":"1","key":"933_CR42","doi-asserted-by":"crossref","first-page":"11","DOI":"10.2174\/1874473710902010011","volume":"2","author":"M Zack","year":"2009","unstructured":"Zack M, Poulos CX (2009) Parallel roles for dopamine in pathological gambling and psychostimulant addiction. Curr Drug Abuse Rev 2(1):11\u201325","journal-title":"Curr Drug Abuse Rev"}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-012-0933-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00702-012-0933-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-012-0933-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,6]],"date-time":"2019-07-06T23:02:12Z","timestamp":1562454132000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00702-012-0933-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,12,12]]},"references-count":41,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["933"],"URL":"https:\/\/doi.org\/10.1007\/s00702-012-0933-5","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,12,12]]}}}