{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:26:37Z","timestamp":1786980397791,"version":"build-2736575974"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2013,4,16]],"date-time":"2013-04-16T00:00:00Z","timestamp":1366070400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1007\/s00702-013-1020-2","type":"journal-article","created":{"date-parts":[[2013,4,15]],"date-time":"2013-04-15T04:24:33Z","timestamp":1365999873000},"page":"1559-1563","source":"Crossref","is-referenced-by-count":5,"title":["Cerebrospinal fluid levels of chromogranin A in the treatment-na\u00efve early stage Parkinson\u2019s disease: a pilot study"],"prefix":"10.1007","volume":"120","author":[{"given":"Michaela","family":"Kaiserov\u00e1","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana P\u0159ikrylov\u00e1","family":"Vranov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Stejskal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate\u0159ina","family":"Men\u0161\u00edkov\u00e1","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Ka\u0148ovsk\u00fd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,4,16]]},"reference":[{"issue":"3","key":"1020_CR1","doi-asserted-by":"crossref","first-page":"40C","DOI":"10.1042\/bj0970040C","volume":"97","author":"P Banks","year":"1965","unstructured":"Banks P, Helle K (1965) The release of protein from the stimulated adrenal medulla. Biochem J 97(3):40C\u201341C","journal-title":"Biochem J"},{"issue":"1","key":"1020_CR2","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.neuroscience.2010.06.057","volume":"170","author":"A Bartolomucci","year":"2010","unstructured":"Bartolomucci A, Pasinetti GM, Salton SR (2010) Granins as disease-biomarkers: translational potential for psychiatric and neurological disorders. Neuroscience 170(1):289\u2013297","journal-title":"Neuroscience"},{"issue":"6","key":"1020_CR3","first-page":"306","volume":"6","author":"K Blennow","year":"1995","unstructured":"Blennow K, Davidsson P, Wallin A, Ekman R (1995) Chromogranin A in cerebrospinal fluid: a biochemical marker for synaptic degeneration in Alzheimer\u2019s disease? Dementia 6(6):306\u2013311","journal-title":"Dementia"},{"issue":"1","key":"1020_CR4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.regpep.2009.11.013","volume":"165","author":"JM Conlon","year":"2010","unstructured":"Conlon JM (2010) Granin-derived peptides as diagnostic and prognostic markers for endocrine tumors. Regul Pept 165(1):5\u201311","journal-title":"Regul Pept"},{"issue":"1","key":"1020_CR5","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s007020050036","volume":"105","author":"U Eder","year":"1998","unstructured":"Eder U, Leitner B, Kirchmair R, Pohl P, Jobst KA, Smith AD, M\u00e1lly J, Benzer A, Riederer P, Reichmann H, Saria A, Winkler H (1998) Levels and proteolytic processing of chromogranin A and B and secretogranin II in cerebrospinal fluid in neurological diseases. J Neural Transm 105(1):39\u201351","journal-title":"J Neural Transm"},{"issue":"6","key":"1020_CR6","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1136\/jnnp.51.6.745","volume":"51","author":"WR Gibb","year":"1988","unstructured":"Gibb WR, Lees AJ (1988) The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson\u2019s disease. J Neurol Neurosurg Psychiatry 51(6):745\u2013752","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"7","key":"1020_CR7","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1172\/JCI25706","volume":"115","author":"T Kim","year":"2005","unstructured":"Kim T, Loh YP (2005) Chromogranin A: a surprising link between granule biogenesis and hypertension. J Clin Invest 115(7):1711\u20131713","journal-title":"J Clin Invest"},{"key":"1020_CR8","doi-asserted-by":"crossref","unstructured":"Loh YP, Cheng Y, Mahata SK, Corti A, Tota B (2012) Chromogranin A and derived peptides in health and disease. J Mol Neurosci 3","DOI":"10.1007\/s12031-012-9728-2"},{"issue":"7","key":"1020_CR9","doi-asserted-by":"crossref","first-page":"1942","DOI":"10.1172\/JCI24354","volume":"115","author":"NR Mahapatra","year":"2005","unstructured":"Mahapatra NR, O\u2019Connor DT, Vaingankar SM, Hikim AP, Mahata M, Ray S, Staite E, Wu H, Gu Y, Dalton N, Kennedy BP, Ziegler MG, Ross J, Mahata SK (2005) Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog. J Clin Invest 115(7):1942\u20131952","journal-title":"J Clin Invest"},{"issue":"11","key":"1020_CR10","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/0006-3223(95)00098-4","volume":"39","author":"C Miller","year":"1996","unstructured":"Miller C, Kirchmair R, Troger J, Saria A, Fleischhacker WW, Fischer-Colbrie R, Benzer A, Winkler H (1996) CSF of neuroleptic-naive first-episode schizophrenic patients: levels of biogenic amines, substance P, and peptides derived from chromogranin A (GE-25) and secretogranin II (secretoneurin). Biol Psychiatry 39(11):911\u2013918","journal-title":"Biol Psychiatry"},{"issue":"2","key":"1020_CR11","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0006-8993(94)91940-2","volume":"634","author":"M Nishimura","year":"1994","unstructured":"Nishimura M, Tomimoto H, Suenaga T, Nakamura S, Namba Y, Ikeda K, Akiguchi I, Kimura J (1994) Synaptophysin and chromogranin A immunoreactivities of Lewy bodies in Parkinson\u2019s disease brains. Brain Res 634(2):339\u2013344","journal-title":"Brain Res"},{"issue":"4","key":"1020_CR12","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/0306-4522(93)90146-7","volume":"56","author":"DT O\u2019Connor","year":"1993","unstructured":"O\u2019Connor DT, Cervenka JH, Stone RA, Parmer RJ, Franco-Bourland RE, Madrazo I, Langlais PJ (1993) Chromogranin A immunoreactivity in human cerebrospinal fluid: properties, relationship to noradrenergic neuronal activity, and variation in neurologic disease. Neuroscience 56(4):999\u20131007","journal-title":"Neuroscience"},{"key":"1020_CR13","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/0-306-46837-9_31","volume":"482","author":"DT O\u2019Connor","year":"2000","unstructured":"O\u2019Connor DT, Mahata SK, Taupenot L, Mahata M, Livsey Taylor CV, Kailasam MT, Ziegler MG, Parmer RJ (2000) Chromogranin A in human disease. Adv Exp Med Biol 482:377\u2013388","journal-title":"Adv Exp Med Biol"},{"issue":"1\u20133","key":"1020_CR14","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.regpep.2008.07.009","volume":"152","author":"A Schrott-Fischer","year":"2009","unstructured":"Schrott-Fischer A, Bitsche M, Humpel C, Walcher C, Maier H, Jellinger K, Rabl W, Glueckert R, Marksteiner J (2009) Chromogranin peptides in amyotrophic lateral sclerosis. Regul Pept 152(1\u20133):13\u201321","journal-title":"Regul Pept"},{"issue":"2\u20133","key":"1020_CR15","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-0173(84)90007-9","volume":"320","author":"P Somogyi","year":"1984","unstructured":"Somogyi P, Hodgson AJ, DePotter RW, Fischer-Colbrie R, Schober M, Winkler H, Chubb IW (1984) Chromogranin immunoreactivity in the central nervous system. Immunochemical characterisation, distribution and relationship to catecholamine and enkephalin pathways. Brain Res 320(2\u20133):193\u2013230","journal-title":"Brain Res"},{"issue":"1","key":"1020_CR16","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1161\/01.HYP.26.1.213","volume":"26","author":"MA Takiyyuddin","year":"1995","unstructured":"Takiyyuddin MA, Parmer RJ, Kailasam MT, Cervenka JH, Kennedy B, Ziegler MG, Lin MC, Li J, Grim CE, Wright FA et al (1995) Chromogranin A in human hypertension. Influence of heredity. Hypertension 26(1):213\u2013220","journal-title":"Hypertension"},{"issue":"12","key":"1020_CR17","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1056\/NEJMra021405","volume":"348","author":"L Taupenot","year":"2003","unstructured":"Taupenot L, Harper KL, O\u2019Connor DT (2003) The chromogranin-secretogranin family. N Engl J Med 348(12):1134\u20131149","journal-title":"N Engl J Med"},{"issue":"3","key":"1020_CR18","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1002\/mds.23453","volume":"26","author":"S Tinaz","year":"2011","unstructured":"Tinaz S, Courtney MG, Stern CE (2011) Focal cortical and subcortical atrophy in early Parkinson\u2019s disease. Mov Disord 26(3):436\u2013441","journal-title":"Mov Disord"},{"issue":"2","key":"1020_CR19","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/0014-5793(90)81408-G","volume":"263","author":"R Weiler","year":"1990","unstructured":"Weiler R, Lassmann H, Fischer P, Jellinger K, Winkler H (1990) A high ratio of chromogranin A to synaptin\/synaptophysin is a common feature of brains in Alzheimer and Pick disease. FEBS Lett 263(2):337\u2013339","journal-title":"FEBS Lett"},{"issue":"5","key":"1020_CR20","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1007\/s00702-011-0648-z","volume":"118","author":"M Willis","year":"2011","unstructured":"Willis M, Leitner I, Jellinger KA, Marksteiner J (2011) Chromogranin peptides in brain diseases. J Neural Transm 118(5):727\u2013735","journal-title":"J Neural Transm"},{"issue":"1","key":"1020_CR21","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0304-3940(94)90227-5","volume":"170","author":"O Yasuhara","year":"1994","unstructured":"Yasuhara O, Kawamata T, Aimi Y, McGeer EG, McGeer PL (1994) Expression of chromogranin A in lesions in the central nervous system from patients with neurological diseases. Neurosci Lett 170(1):13\u201316","journal-title":"Neurosci Lett"}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-013-1020-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00702-013-1020-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-013-1020-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T11:05:31Z","timestamp":1562929531000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00702-013-1020-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,4,16]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["1020"],"URL":"https:\/\/doi.org\/10.1007\/s00702-013-1020-2","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,4,16]]}}}