{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T12:42:27Z","timestamp":1774788147519,"version":"3.50.1"},"reference-count":38,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2014,6,14]],"date-time":"2014-06-14T00:00:00Z","timestamp":1402704000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1007\/s00702-014-1254-7","type":"journal-article","created":{"date-parts":[[2014,6,13]],"date-time":"2014-06-13T07:17:54Z","timestamp":1402643874000},"page":"301-306","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Influence of comorbid alcohol use disorder on treatment response of depressive patients"],"prefix":"10.1007","volume":"122","author":[{"given":"Eri","family":"Hashimoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaya","family":"Tayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromi","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumi","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshikazu","family":"Saito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,6,14]]},"reference":[{"key":"1254_CR1","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1001\/archpsyc.56.4.356","volume":"56","author":"I Agartz","year":"1999","unstructured":"Agartz I, Momenan R, Rawlings RR et al (1999) Hippocampal volume in patients with alcohol dependence. Arch Gen Psychiat 56:356\u2013363","journal-title":"Arch Gen Psychiat"},{"key":"1254_CR2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1093\/alcalc\/agp005","volume":"44","author":"AA Badawy","year":"2009","unstructured":"Badawy AA, Doughrty DM, Marsh-Richard DM et al (2009) Activation of liver tryptophan pyrrolase mediates the decrease in tryptophan availability to the brain after acute alcohol consumption by normal subjects. Alcohol Alcohol 44:267\u2013271","journal-title":"Alcohol Alcohol"},{"key":"1254_CR3","first-page":"181","volume":"1","author":"JM Bertolote","year":"2002","unstructured":"Bertolote JM, Fleischmann A (2002) Suicide and psychiatric diagnosis: a worldwide perspective. World Psychiat Off J World Psychiatric Assoc (WPA) 1:181\u2013185","journal-title":"World Psychiat Off J World Psychiatric Assoc (WPA)"},{"issue":"129\u2013130","key":"1254_CR4","first-page":"135","volume":"7","author":"JD Bremner","year":"2002","unstructured":"Bremner JD (2002) Structural changes in the brain in depression and relationship to symptom recurrence. CNS Spectr 7(129\u2013130):135\u2013139","journal-title":"CNS Spectr"},{"key":"1254_CR5","doi-asserted-by":"crossref","first-page":"742","DOI":"10.3928\/00485713-20081101-04","volume":"38","author":"KR Conner","year":"2008","unstructured":"Conner KR, McCloskey MS, Duberstein PR (2008) Psychiatric risk factors for suicide in the alcohol-dependent patient. Psychiatr Ann 38:742\u2013748","journal-title":"Psychiatr Ann"},{"key":"1254_CR6","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1111\/j.1530-0277.1996.tb01148.x","volume":"20","author":"JR Cornelius","year":"1996","unstructured":"Cornelius JR, Salloum IM, Day NL et al (1996) Patterns of suicidality and alcohol use in alcoholics with major depression. Alcohol Clin Exp Res 20:1451\u20131455","journal-title":"Alcohol Clin Exp Res"},{"key":"1254_CR7","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.alcohol.2004.04.005","volume":"33","author":"FT Crews","year":"2004","unstructured":"Crews FT, Nixon K, Wilkie ME (2004) Exercise reverses ethanol inhibition of neural stem cell proliferation. Alcohol 33:63\u201371","journal-title":"Alcohol"},{"key":"1254_CR8","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.comppsych.2004.07.025","volume":"46","author":"LL Davis","year":"2005","unstructured":"Davis LL, Rush JA, Wisniewski SR et al (2005) Substance use disorder comorbidity in major depressive disorder: an exploratory analysis of the Sequenced Treatment Alternatives to Relieve Depression cohort. Compr Psychiatry 46:81\u201389","journal-title":"Compr Psychiatry"},{"key":"1254_CR9","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1080\/10550490600754317","volume":"15","author":"LL Davis","year":"2006","unstructured":"Davis LL, Frazier E, Husain MM et al (2006) Substance use disorder comorbidity in major depressive disorder: a confirmatory analysis of the STAR*D cohort. Am J Addict 15:278\u2013285","journal-title":"Am J Addict"},{"key":"1254_CR10","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.drugalcdep.2009.10.003","volume":"107","author":"LL Davis","year":"2010","unstructured":"Davis LL, Wisniewski SR, Howland RH et al (2010) Does comorbid subsutance use disorder impair recovery from major depression with SSRI treatment? an analysis of the STAR*D level one treatment outcomes. Drug Alcohol Depend 107:161\u2013170","journal-title":"Drug Alcohol Depend"},{"key":"1254_CR11","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1111\/j.1360-0443.2006.01606.x","volume":"101","author":"DM Donovan","year":"2006","unstructured":"Donovan DM, Kivlahan DR, Doyle SR et al (2006) Concurrent validity of the Alcohol Use Disorders Identification Test (AUDIT) and AUDIT zones in defining levels of severity among out-patients with alcohol dependence in the COMBINE study. Addiction 101:1696\u20131704","journal-title":"Addiction"},{"key":"1254_CR12","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1530-0277.1999.tb04033.x","volume":"23","author":"JC Fortney","year":"1999","unstructured":"Fortney JC, Booth BM, Curran GM (1999) Do patients with alcohol dependence use more services? a comparative analysis with other chronic disorders. Alcohol Clin Exp Res 23:127\u2013133","journal-title":"Alcohol Clin Exp Res"},{"key":"1254_CR13","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0376-8716(00)00216-7","volume":"63","author":"SE Gilman","year":"2001","unstructured":"Gilman SE, Abraham HD (2001) A longitudinal study of the order of onset of alcohol dependence and major depression. Drug Alcohol Depend 63:277\u2013286","journal-title":"Drug Alcohol Depend"},{"key":"1254_CR14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0899-3289(99)80131-X","volume":"10","author":"BF Grant","year":"1998","unstructured":"Grant BF, Dawson DA (1998) Age of onset of drug use and its association with DSM-IV drug abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. J Subst Abuse 10:163\u2013173","journal-title":"J Subst Abuse"},{"key":"1254_CR15","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0376-8716(95)01160-4","volume":"39","author":"BF Grant","year":"1995","unstructured":"Grant BF, Hartford TC (1995) Comorbidity between DSM-IV alcohol use disorders and major depression: results of a national survey. Drug Alcohol Depend 39:197\u2013206","journal-title":"Drug Alcohol Depend"},{"key":"1254_CR16","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","volume":"23","author":"M Hamilton","year":"1960","unstructured":"Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg 23:56\u201362","journal-title":"J Neurol Neurosurg"},{"key":"1254_CR17","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1001\/archpsyc.59.9.794","volume":"59","author":"DS Hasin","year":"2002","unstructured":"Hasin DS, Grant BF (2002) Major depression in 6050 former drinkers: association with past alcohol dependence. Arch Gen Psychiat 59:794\u2013800","journal-title":"Arch Gen Psychiat"},{"key":"1254_CR18","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1001\/archpsyc.59.4.375","volume":"59","author":"DS Hasin","year":"2002","unstructured":"Hasin DS, Liu X, Nunes E et al (2002) Effects of major depression on remission and relapse of substance dependence. Arch Gen Psychiat 59:375\u2013380","journal-title":"Arch Gen Psychiat"},{"key":"1254_CR19","first-page":"437","volume":"31","author":"H Hiro","year":"1996","unstructured":"Hiro H, Shima S (1996) Availability of the Alochol Use Disorders Identification Test (AUDIT) for a complete health examination in Japan. Jpn J Alcohol Drug Depend 31:437\u2013450 (in Japanese)","journal-title":"Jpn J Alcohol Drug Depend"},{"key":"1254_CR20","first-page":"589","volume":"55","author":"H Hiro","year":"1997","unstructured":"Hiro H, Shima S (1997) The effectiveness of CAGE and AUDIT in the detection of problem drinkers. Jpn J Clin Med 55:589\u2013593 (in Japanese)","journal-title":"Jpn J Clin Med"},{"key":"1254_CR21","first-page":"1443","volume":"9","author":"A Inagaki","year":"2006","unstructured":"Inagaki A, Inada T (2006) Dose equivalence of psychotropic drugs. Part X VIII: dose equivalence of psychotropic drugs: 2006-Version. Jpn J Clin Psychopharmacol 9:1443\u20131447 (in Japanese)","journal-title":"Jpn J Clin Psychopharmacol"},{"key":"1254_CR22","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.4088\/JCP.10m06217","volume":"72","author":"N Iovieno","year":"2011","unstructured":"Iovieno N, Tedeschini E, Bentley KH et al (2011) Antidepressants for major depressive disorder and dysthymic disorder in patients with comorbid alcohol use disoreders: a meta-analysis of placebo-controlled randomized trials. J Clin Psychiatry 72:1144\u20131151","journal-title":"J Clin Psychiatry"},{"key":"1254_CR23","first-page":"232","volume":"53","author":"RC Kessler","year":"1997","unstructured":"Kessler RC, Crum RM, Warner LA et al (1997) Lifetime co-occurrence of DSM-III-R alcohol abuse and dependence with other psychiatric disorders in the National Comorbidity Survey. Arch Gen Psychiatry 53:232\u2013240","journal-title":"Arch Gen Psychiatry"},{"key":"1254_CR24","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1176\/ajp.151.5.701","volume":"151","author":"TI Mueller","year":"1994","unstructured":"Mueller TI, Lavori PW, Keller MB et al (1994) Prognostic effect of the variable course of alcoholism on the 10-year course of depression. Am J Psychiat 151:701\u2013706","journal-title":"Am J Psychiat"},{"issue":"1","key":"1254_CR25","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1471-244X-9-31","volume":"9","author":"A Nandi","year":"2009","unstructured":"Nandi A, Beard JR, Galea S (2009) Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population: a systematic review. BMC Psychiatry 9(1):31","journal-title":"BMC Psychiatry"},{"key":"1254_CR26","doi-asserted-by":"crossref","first-page":"9714","DOI":"10.1523\/JNEUROSCI.3063-04.2004","volume":"24","author":"K Nixon","year":"2004","unstructured":"Nixon K, Crews FT (2004) Temporally specific burst in cell proliferation increases hippocampal neurogenesis in protracted abstinence from alcohol. J Neurosci 24:9714\u20139722","journal-title":"J Neurosci"},{"key":"1254_CR27","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1001\/jama.291.15.1887","volume":"291","author":"E Nunes","year":"2004","unstructured":"Nunes E, Levin F (2004) Treatment of depression in patients with alcohol or other drug dependence. A meta-analysis. JAMA 291:1887\u20131896","journal-title":"JAMA"},{"key":"1254_CR28","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1111\/j.1440-1819.2005.01408.x","volume":"59","author":"T Otsubo","year":"2005","unstructured":"Otsubo T, Tanaka K, Koda R et al (2005) Reliability and validity of Japanese version of the Mini-International Neuropsychiatric Interview. Psychiatry Clin Neurosci 59:517\u2013526","journal-title":"Psychiatry Clin Neurosci"},{"key":"1254_CR29","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/BF01244984","volume":"94","author":"H Ozawa","year":"1993","unstructured":"Ozawa H, Gsell W, Fr\u00f6lich L et al (1993) Imbalance of the Gs and Gi\/o function in post-mortem human brain of depressed patients. J Neural Transm Gen Sect 94:63\u201369","journal-title":"J Neural Transm Gen Sect"},{"issue":"Suppl","key":"1254_CR30","doi-asserted-by":"crossref","first-page":"46S","DOI":"10.1111\/j.1530-0277.2001.tb02372.x","volume":"25","author":"SC Pandey","year":"2001","unstructured":"Pandey SC, Saito T, Yoshimura M et al (2001) cAmp signaling cascade: a promising role in ethanol tolerance and dependence. Alcohol Clin Exp Res 25(Suppl):46S\u201348S","journal-title":"Alcohol Clin Exp Res"},{"key":"1254_CR31","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.biopsych.2004.07.016","volume":"56","author":"HM Pettinati","year":"2004","unstructured":"Pettinati HM (2004) Antidepressant treatment of co-occurring depression and alcohol dependence. Biol Psychiatry 56:785\u2013792","journal-title":"Biol Psychiatry"},{"key":"1254_CR32","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1176\/appi.ajp.2012.12010112","volume":"170","author":"HM Pettinati","year":"2013","unstructured":"Pettinati HM, O\u2019Brien CP, Dundon WD (2013) Current status of co-occurring mood and substance use disorders: a new therapeutic target. Am J Psychiatry 170:23\u201330","journal-title":"Am J Psychiatry"},{"key":"1254_CR33","doi-asserted-by":"crossref","unstructured":"Saunders JB, Aasland OG, Babor TF et al (1993) Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption-II. Addiciton (Abingdon, England) 88:791\u2013804","DOI":"10.1111\/j.1360-0443.1993.tb02093.x"},{"key":"1254_CR34","doi-asserted-by":"crossref","first-page":"907","DOI":"10.4088\/JCP.v69n0604","volume":"69","author":"L Sher","year":"2008","unstructured":"Sher L, Stanley BH, Harkavy-Friedman JM et al (2008) Depressed patients with co-occurring alcohol use disorders: a unique patient population. J Clin Psychiatry 69:907\u2013915","journal-title":"J Clin Psychiatry"},{"key":"1254_CR35","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.amjmed.2005.01.007","volume":"118","author":"LE Sullivan","year":"2005","unstructured":"Sullivan LE, Fiellin DA, O\u2019Conner PG (2005) The prevalence and impact of alcohol problems in major depression: a systematic review. Am J Med 118:330\u2013341","journal-title":"Am J Med"},{"key":"1254_CR36","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.psychres.2006.07.004","volume":"153","author":"H Tabuse","year":"2007","unstructured":"Tabuse H, Kalali A, Azuma H et al (2007) The new GRID Hamilton Rating Scale for Depression demonstrates excellent inter-rater reliability for inexperienced and experienced raters before and after training. Psychiat Res 153:61\u201367","journal-title":"Psychiat Res"},{"key":"1254_CR37","first-page":"704","volume":"44","author":"W Ukai","year":"2009","unstructured":"Ukai W, Ishii T, Hashimoto E et al (2009) The common aspects of pathophysiology of alcoholism and depression. Jap J Alcohol Drug Dependence 44:704\u2013711","journal-title":"Jap J Alcohol Drug Dependence"},{"key":"1254_CR38","unstructured":"World Health Organization (1992) The ICD-10 Classification of Mental and Behavioural Disorders: Clinical descriptions and diagnostic guidelines, Geneva"}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-014-1254-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00702-014-1254-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-014-1254-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T04:30:29Z","timestamp":1559104229000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00702-014-1254-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,6,14]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2015,2]]}},"alternative-id":["1254"],"URL":"https:\/\/doi.org\/10.1007\/s00702-014-1254-7","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6,14]]}}}