{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T21:34:33Z","timestamp":1768512873284,"version":"3.49.0"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T00:00:00Z","timestamp":1472774400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s00702-016-1612-8","type":"journal-article","created":{"date-parts":[[2016,9,2]],"date-time":"2016-09-02T23:28:21Z","timestamp":1472858901000},"page":"1381-1386","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Prevalence of small intestinal bacterial overgrowth in Chinese patients with Parkinson\u2019s disease"],"prefix":"10.1007","volume":"123","author":[{"given":"Xiao-Lu","family":"Niu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Xiu","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qing","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Hua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Long","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He-Hua","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,9,2]]},"reference":[{"key":"1612_CR1","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1002\/mds.22643","volume":"24","author":"P Barone","year":"2009","unstructured":"Barone P, Antonini A, Colosimo C, Marconi R, Morgante L, Avarello TP, Bottacchi E, Cannas A, Ceravolo G, Ceravolo R, Cicarelli G, Gaglio RM, Giglia RM, Iemolo F, Manfredi M, Meco G, Nicoletti A, Pederzoli M, Petrone A, Pisani A, Pontieri FE, Quatrale R, Ramat S, Scala R, Volpe G, Zappulla S, Bentivoglio AR, Stocchi F, Trianni G, Dotto PD, PRIAMO study group (2009) The PRIAMO study: a multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson\u2019s disease. Mov Disord 24:1641\u20131649","journal-title":"Mov Disord"},{"key":"1612_CR2","doi-asserted-by":"crossref","first-page":"2978","DOI":"10.3748\/wjg.v16.i24.2978","volume":"16","author":"J Bures","year":"2010","unstructured":"Bures J, Cyrany J, Kohoutova D, Forstyl M, Rejchrt S, Kvetina J (2010) Small intestinal bacterial overgrowth. World J Gastroenterol 16:2978\u20132990","journal-title":"World J Gastroenterol"},{"key":"1612_CR3","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1002\/mds.21596","volume":"22","author":"KR Chaudhuri","year":"2007","unstructured":"Chaudhuri KR, Martinez-Martin P, Brown RG, Sethi K, Stocchi F, Odin P, Ondo W, Abe K, Macphee G, Macmahon D, Barone P, Rabey M, Forbes A, Breen K, Tluk S, Naidu Y, Olanow W, Williams AJ, Thomas S, Rye D, Tsuboi Y, Hand A, Schapira AH (2007) The metric properties of a novel non-motor symptoms scale for Parkinson\u2019s disease: results from an international pilot study. Mov Disord 22:1901\u20131911","journal-title":"Mov Disord"},{"issue":"10","key":"1612_CR4","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.parkreldis.2015.08.020","volume":"21","author":"H Chen","year":"2015","unstructured":"Chen H, Ding D, Wang J, Zhao Q, Meng H, Li H, Gao YT, Shu XO, Tanner CM, Hong Z, Yang G (2015) Parkinson\u2019s disease research in a prospective cohort in China. Parkinsonism Relat Disord 21(10):1200\u20131204","journal-title":"Parkinsonism Relat Disord"},{"issue":"9","key":"1612_CR5","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/nmo.12198","volume":"25","author":"TG Dinan","year":"2013","unstructured":"Dinan TG, Cryan JF (2013) Melancholic microbes: a link between gut microbiota and depression? Neurogastroenterol Motil 25(9):713\u2013719","journal-title":"Neurogastroenterol Motil"},{"key":"1612_CR6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/hel.12035","volume":"18","author":"SM Dobbs","year":"2013","unstructured":"Dobbs SM, Charlett A, Dobbs RJ, Weller C, Iguodala O, Smee C, Lawson AJ, Taylor D, Bjarnason I (2013) Antimicrobial surveillance in idiopathic parkinsonism: indication-specific improvement in hypokinesia following Helicobacter pylori eradication and non-specific effect of antimicrobials for other indications in worsening rigidity. Helicobacter 18:187\u2013196","journal-title":"Helicobacter"},{"issue":"9","key":"1612_CR7","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1002\/mds.25522","volume":"28","author":"A Fasano","year":"2013","unstructured":"Fasano A, Bove F, Gabrielli M, Petracca M, Zocco MA, Ragazzoni E, Barbaro F, Piano C, Fortuna S, Tortora A, Di Giacopo R, Campanale M, Gigante G, Lauritano EC, Navarra P, Marconi S, Gasbarrini A, Bentivoglio AR (2013) The role of small intestinal bacterial overgrowth in Parkinson\u2019s disease. Mov Disord 28(9):1241\u20131249","journal-title":"Mov Disord"},{"key":"1612_CR8","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1111\/j.1365-2036.2010.04436.x","volume":"32","author":"M Furnari","year":"2010","unstructured":"Furnari M, Parodi A, Gemignani L, Giannini EG, Marenco S, Savarino E, Assandri L, Fazio V, Bonfanti D, Inferrera S, Savarino V (2010) Clinical trial: the combination of rifaximin with partially hydrolysed guar gum is more effective than rifaximin alone in eradicating small intestinal bacterial overgrowth. Aliment Pharmacol Ther 32:1000\u20131006","journal-title":"Aliment Pharmacol Ther"},{"issue":"5","key":"1612_CR9","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1002\/mds.23566","volume":"26","author":"M Gabrielli","year":"2011","unstructured":"Gabrielli M, Bonazzi P, Scarpellini E, Bendia E, Lauritano EC, Fasano A, Ceravolo MG, Capecci M, Rita Bentivoglio A, Provinciali L, Tonali PA, Gasbarrini A (2011) Prevalence of small intestinal bacterial overgrowth in Parkinson\u2019s disease. Mov Disord 26(5):889\u2013892","journal-title":"Mov Disord"},{"key":"1612_CR10","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000103892","volume":"25","author":"A Gasbarrini","year":"2007","unstructured":"Gasbarrini A, Lauritano EC, Gabrielli M, Scarpellini E, Lupascu A, Ojetti V, Gasbarrini G (2007) Small intestinal bacterial overgrowth: diagnosis and treatment. Dig Dis 25:237\u2013240","journal-title":"Dig Dis"},{"key":"1612_CR11","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1001\/archneur.56.1.33","volume":"56","author":"DJ Gelb","year":"1999","unstructured":"Gelb DJ, Oliver E, Gilman S (1999) Diagnostic criteria for Parkinson disease. Arch Neurol 56:33\u201339","journal-title":"Arch Neurol"},{"key":"1612_CR12","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/mds.20213","volume":"19","author":"CG Goetz","year":"2004","unstructured":"Goetz CG, Poewe W, Rascol O, Sampaio C, Stebbins GT, Counsell C, Giladi N, Holloway RG, Moore CG, Wenning GK, Yahr MD, Seidl L, Movement Disorder Society Task Force on Rating Scales for Parkinson\u2019s Disease (2004) Movement Disorder Society Task Force report on the Hoehn and Yahr staging scale: status and recommendations. Mov Disord 19:1020\u20131028","journal-title":"Mov Disord"},{"issue":"1","key":"1612_CR13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/mds.25150","volume":"28","author":"K Kieburtz","year":"2013","unstructured":"Kieburtz K, Wunderle KB (2013) Parkinson\u2019s disease: evidence for environmental risk factors. Mov Disord 28(1):8\u201313","journal-title":"Mov Disord"},{"key":"1612_CR14","doi-asserted-by":"crossref","first-page":"4180","DOI":"10.1210\/jc.2007-0606","volume":"92","author":"EC Lauritano","year":"2007","unstructured":"Lauritano EC, Bilotta AL, Gabrielli M, Scarpellini E, Lupascu A, Laginestra A, Novi M, Sottili S, Serricchio M, Cammarota G, Gasbarrini G, Pontecorvi A, Gasbarrini A (2007) Association between hypothyroidism and small intestinal bacterial overgrowth. J Clin Endocrinol Metab 92:4180\u20134184","journal-title":"J Clin Endocrinol Metab"},{"key":"1612_CR15","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.jpeds.2009.10.043","volume":"156","author":"A Leiby","year":"2010","unstructured":"Leiby A, Mehta D, Gopalareddy V, Jackson-Walker S, Horvath K (2010) Bacterial overgrowth and methane production in children with encopresis. J Pediatr 156:766\u2013770","journal-title":"J Pediatr"},{"key":"1612_CR16","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.autneu.2006.02.015","volume":"126\u2013127","author":"AE Lomax","year":"2006","unstructured":"Lomax AE, Linden DR, Mawe GM, Sharkey KA (2006) Effects of gastrointestinal inflammation on enteroendocrine cells and enteric neural reflex circuits. Auton Neurosci 126\u2013127:250\u2013257","journal-title":"Auton Neurosci"},{"key":"1612_CR17","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.neuroscience.2015.05.016","volume":"300","author":"KR Magnusson","year":"2015","unstructured":"Magnusson KR, Hauck L, Jeffrey BM et al (2015) Relationships between diet-related changes in the gut microbiome and cognitive flexibility. Neuroscience 300:128\u2013140","journal-title":"Neuroscience"},{"key":"1612_CR18","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1002\/mds.10473","volume":"18","author":"Movement Disorder Society Task Force on Rating Scales for Parkinson\u2019s Disease","year":"2003","unstructured":"Movement Disorder Society Task Force on Rating Scales for Parkinson\u2019s Disease (2003) The Unified Parkinson\u2019s Disease Rating Scale (UPDRS): status and recommendations. Mov Disord 18:738\u2013750","journal-title":"Mov Disord"},{"key":"1612_CR19","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1111\/j.1365-2036.2005.02493.x","volume":"21","author":"G Nucera","year":"2005","unstructured":"Nucera G, Gabrielli M, Lupascu A, Lauritano EC, Santoliquido A, Cremonini F, Cammarota G, Tondi P, Pola P, Gasbarrini G, Gasbarrini A (2005) Abnormal breath tests to lactose, fructose and sorbitol in irritable bowel syndrome may be explained by small intestinal bacterial overgrowth. Aliment Pharmacol Ther 21:1391\u20131395","journal-title":"Aliment Pharmacol Ther"},{"key":"1612_CR20","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1046\/j.1365-2389.2003.51259.x","volume":"51","author":"A Parlesak","year":"2003","unstructured":"Parlesak A, Klein B, Schecher K, Bode JC, Bode C (2003) Prevalence of small bowel bacterial overgrowth and its association with nutrition intake in nonhospitalized older adults. J Am Geriatr Soc 51:768\u2013773","journal-title":"J Am Geriatr Soc"},{"key":"1612_CR21","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1212\/01.wnl.0000221672.01272.ba","volume":"66","author":"M Pierantozzi","year":"2006","unstructured":"Pierantozzi M, Pietroiusti A, Brusa L, Galati S, Stefani A, Lunardi G, Fedele E, Sancesario G, Bernardi G, Bergamaschi A, Magrini A, Stanzione P, Galante A (2006) Helicobacter pylori eradication and L-dopa absorption in patients with PD and motor fluctuations. Neurology 66:1824\u20131829","journal-title":"Neurology"},{"issue":"S17","key":"1612_CR22","doi-asserted-by":"crossref","first-page":"S374","DOI":"10.1002\/mds.21681","volume":"22","author":"W Poewe","year":"2007","unstructured":"Poewe W (2007) Dysautonomia and cognitive dysfunction in Parkinson\u2019s disease. Mov Disord 22(S17):S374\u2013S378","journal-title":"Mov Disord"},{"issue":"3","key":"1612_CR23","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/mds.26069","volume":"30","author":"F Scheperjans","year":"2015","unstructured":"Scheperjans F, Aho V, Pereira PA, Koskinen K, Paulin L, Pekkonen E, Haapaniemi E, Kaakkola S, Eerola-Rautio J, Pohja M, Kinnunen E, Murros K, Auvinen P (2015) Gut microbiota are related to Parkinson\u2019s disease and clinical phenotype. Mov Disord 30(3):350\u2013358","journal-title":"Mov Disord"},{"issue":"5","key":"1612_CR24","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.parkreldis.2014.02.019","volume":"20","author":"AH Tan","year":"2014","unstructured":"Tan AH, Mahadeva S, Thalha AM, Gibson PR, Kiew CK, Yeat CM, Ng SW, Ang SP, Chow SK, Tan CT, Yong HS, Marras C, Fox SH, Lim SY (2014) Small intestinal bacterial overgrowth in Parkinson\u2019s disease. Parkinsonism Relat Disord 20(5):535\u2013540","journal-title":"Parkinsonism Relat Disord"},{"key":"1612_CR25","first-page":"917","volume-title":"ROME III, the functional gastrointestinal disorders","author":"WG Thompson","year":"2006","unstructured":"Thompson WG, Drossman DA, Talley NJ et al (2006) Rome III diagnostic questionnaire for the adult functional GI disorders (including alarm questions) and scoring algorithm. In: Drossman DA, Corazziari E, Delvaux M et al (eds) ROME III, the functional gastrointestinal disorders, 3rd edn. Degnon Associates, McLean, pp 917\u2013951","edition":"3"},{"key":"1612_CR26","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.2337\/diacare.23.8.1200","volume":"23","author":"B Zietz","year":"2000","unstructured":"Zietz B, Lock G, Straub RH, Braun B, Scholmerich J, Palitzsch KD (2000) Small-bowel bacterial overgrowth in diabetic subjects is associated with cardiovascular autonomic neuropathy. Diabetes Care 23:1200\u20131201","journal-title":"Diabetes Care"}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-016-1612-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00702-016-1612-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-016-1612-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,24]],"date-time":"2017-06-24T21:56:18Z","timestamp":1498341378000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00702-016-1612-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,2]]},"references-count":26,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["1612"],"URL":"https:\/\/doi.org\/10.1007\/s00702-016-1612-8","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,2]]}}}