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Buhmann received a grant from the Georg & J\u00fcrgen Rickertsen Stiftung Hamburg, served on a scientific advisory boards for Bial and Zambon and received honoraria for lectures from Abbvie, Bial, GE Healthcare, Gr\u00fcnenthal,\u00a0Licher and UCB Pharma. C. Gerloff is supported by the German Research Foundation (DFG Ge 844\/4-1, Ge 844\/5-1, SFB 936\/C1, Z1, Z2, TRR 169\/A03) and the EU (FP7-HEALTH-2011-278276), and has received honoraria as a speaker or consultant from Amgen, Bayer Vital, BMS, Boehringer Ingelheim, Sanofi Aventis. O. Fr\u00fcndt was supported by AbbVie and Abbott\/St.Jude Medical to attend symposia\/congresses. B. Sch\u00f6nwald received honoraria for lectures from Licher and Zambon.\u00a0B. M\u00fcller received financial compensation for a lecture from Gr\u00fcnenthal. \ufeffT. Mainka and P. Dicusar\u00a0report no conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"For this type of study formal consent is not required (reference number of the Hamburg ethics committee PV5799, WF-028\/18).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"As this is a retrospective analysis of clinical data, this is not applicable. All patients signed a treatment contract with our clinic.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}