{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T19:01:17Z","timestamp":1780513277263,"version":"3.54.1"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T00:00:00Z","timestamp":1556755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s00702-019-02007-x","type":"journal-article","created":{"date-parts":[[2019,5,2]],"date-time":"2019-05-02T15:02:46Z","timestamp":1556809366000},"page":"759-770","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Administration of memantine reverses behavioral, histological, and electrophysiological abnormalities in rats subjected to early maternal deprivation"],"prefix":"10.1007","volume":"126","author":[{"given":"Ezequiel","family":"Uribe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dulce","family":"Pacheco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nieves","family":"Nayadoleni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Eblen-Zajjur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,5,2]]},"reference":[{"issue":"5","key":"2007_CR1","doi-asserted-by":"publisher","first-page":"e804","DOI":"10.1038\/tp.2016.63","volume":"6","author":"GN Andrade","year":"2016","unstructured":"Andrade GN, Butler JS, Peters GA, Molholm S, Foxe JJ (2016) Atypical visual and somatosensory adaptation in schizophrenia-spectrum disorders. Transl Psychiatry 6(5):e804","journal-title":"Transl Psychiatry"},{"key":"2007_CR2","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1016\/j.nbd.2011.10.006","volume":"45","author":"DT Balu","year":"2012","unstructured":"Balu DT, Basu AC, Corradi JP, Cacace AM, Coyle JT (2012) The NMDA receptor coagonists, d-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex. Neurobiol Dis 45:671\u2013682","journal-title":"Neurobiol Dis"},{"key":"2007_CR3","doi-asserted-by":"publisher","first-page":"1896","DOI":"10.3389\/fpsyg.2016.01896","volume":"7","author":"J Balz","year":"2016","unstructured":"Balz J, Romero YR, Keil J, Krebber M, Niedeggen M, Gallinat J, Senkowski D (2016) Beta\/gamma oscillations and event-related potentials indicate aberrant multisensory processing in schizophrenia. Front Psychol 7:1896","journal-title":"Front Psychol"},{"key":"2007_CR4","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1007\/s00429-014-0955-x","volume":"221","author":"CS Barz","year":"2014","unstructured":"Barz CS, Bessaih T, Abel T, Feldmeyer D, Contreras D (2014) Sensory encoding in Neuregulin 1 mutants. Brain Struct Funct 221:1067\u20131081","journal-title":"Brain Struct Funct"},{"key":"2007_CR5","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/s002130051015","volume":"144","author":"A Becker","year":"1999","unstructured":"Becker A, Grecksch G, Bernstein HG, Hollt V, Bogerts B (1999) Social behavior in rats lesioned with ibotenic acid in the hippocampus: quantitative and qualitative analysis. Psychopharmacology 144:333\u2013338","journal-title":"Psychopharmacology"},{"key":"2007_CR6","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.schres.2016.03.025","volume":"175","author":"S Bergh","year":"2016","unstructured":"Bergh S, Hjorthoj C, Sorensen HJ, Fagerlund B, Austin S, Secher RG, Jepsen JR, Nordentoft M (2016) Predictors and longitudinal course of cognitive functioning in schizophrenia spectrum disorders, 10\u00a0years after baseline: the OPUS study. Schizophr Res 175:57\u201363","journal-title":"Schizophr Res"},{"issue":"2","key":"2007_CR7","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1016\/j.brainresrev.2008.12.023","volume":"60","author":"M Butz","year":"2009","unstructured":"Butz M, W\u00f6rg\u00f6tter F, Van Ooyen A (2009) Activity-dependent structural plasticity. Brain Res Rev 60(2):287\u2013305","journal-title":"Brain Res Rev"},{"key":"2007_CR8","first-page":"352","volume":"21","author":"B Cabuk","year":"2011","unstructured":"Cabuk B, Etus V, Bozkurt SU, Sav A, Ceylan S (2011) Neuroprotective effect of memantine on hippocampal neurons in infantile rat hydrocephalus. Turk Neurosurg 21:352\u2013358","journal-title":"Turk Neurosurg"},{"issue":"4","key":"2007_CR9","doi-asserted-by":"publisher","first-page":"1458","DOI":"10.1002\/hbm.22715","volume":"36","author":"MM Chakravarty","year":"2015","unstructured":"Chakravarty MM, Rapoport JL, Giedd JN, Raznahan A, Shaw P, Collins DL, Gogtay N (2015) Striatal shape abnormalities as novel neurodevelopmental endophenotypes in schizophrenia: a longitudinal study. Hum Brain Map\u00a036(4):1458\u20131469","journal-title":"Hum Brain Map"},{"key":"2007_CR10","first-page":"107","volume":"46","author":"HW Clement","year":"1995","unstructured":"Clement HW, Grote C, Svensson L, Engel J, Zofel P, Wesemann W (1995) In vivo studies on the effects of memantine on dopamine metabolism in the striatum and n. accumbens of the rat. J Neural Transm Suppl 46:107\u2013115","journal-title":"J Neural Transm Suppl"},{"issue":"1","key":"2007_CR11","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1038\/nprot.2006.2","volume":"1","author":"R Deacon","year":"2006","unstructured":"Deacon R, Rawlins N (2006) T-maze alternation in the rodent. Nat Protoc J 1(1):7\u201312","journal-title":"Nat Protoc J"},{"key":"2007_CR12","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1097\/YCO.0000000000000154","volume":"28","author":"D Dodell-Feder","year":"2015","unstructured":"Dodell-Feder D, Tully LM, Hooker CI (2015) Social impairment in schizophrenia: new approaches for treating a persistent problem. Curr Opin Psychiatry 28:236\u2013242","journal-title":"Curr Opin Psychiatry"},{"issue":"1","key":"2007_CR13","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.neuron.2017.03.019","volume":"94","author":"JP Hamm","year":"2017","unstructured":"Hamm JP, Peterka DS, Gogos JA, Yuste R (2017) Altered cortical ensembles in mouse models of schizophrenia. Neuron 94(1):153\u2013167","journal-title":"Neuron"},{"issue":"1","key":"2007_CR14","first-page":"A1","volume":"6","author":"WJ Heitler","year":"2007","unstructured":"Heitler WJ (2007) DataView: a tutorial tool for data analysis. Template-based spike sorting and frequency analysis. J Undergrad Neurosci Educ 6(1):A1","journal-title":"J Undergrad Neurosci Educ"},{"key":"2007_CR15","volume-title":"Guide for the care and use of laboratory animals","author":"Institute of Laboratory Animal Resources (US)","year":"2011","unstructured":"Institute of Laboratory Animal Resources (US) (2011) Guide for the care and use of laboratory animals, 11th edn. National Academies Press, Washington","edition":"11"},{"key":"2007_CR16","doi-asserted-by":"publisher","first-page":"1117","DOI":"10.1093\/cercor\/bhu293","volume":"26","author":"V Jeevakumar","year":"2016","unstructured":"Jeevakumar V, Kroener S (2016) Ketamine administration during the second postnatal week alters synaptic properties of fast-spiking interneurons in the medial prefrontal cortex of adult mice. Cereb Cortex 26:1117\u20131129","journal-title":"Cereb Cortex"},{"key":"2007_CR17","first-page":"e2473","volume":"48","author":"O Kaidanovich-Beilin","year":"2011","unstructured":"Kaidanovich-Beilin O, Lipina T, Vukobradovic I, Roder J, Woodgett JR (2011) Assessment of social interaction behaviors. J Vis Exp 48:e2473","journal-title":"J Vis Exp"},{"key":"2007_CR18","first-page":"104","volume":"10","author":"J Keil","year":"2016","unstructured":"Keil J, Romero YR, Balz J, Henjes M, Senkowski D (2016) Positive and negative symptoms in schizophrenia relate to distinct oscillatory signatures of sensory gating. Front Hum Neurosci 10:104","journal-title":"Front Hum Neurosci"},{"key":"2007_CR19","volume-title":"Electrodiagnosis in diseases of nerve and muscle: principles and practice","author":"J Kimura","year":"2001","unstructured":"Kimura J (2001) Electrodiagnosis in diseases of nerve and muscle: principles and practice. Oxford University Press, Oxford"},{"issue":"4","key":"2007_CR20","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1093\/schbul\/sbv228","volume":"42","author":"NV Kraguljac","year":"2016","unstructured":"Kraguljac NV, White DM, Hadley N, Hadley JA, Ver HL, Davis E, Lahti AC (2016) Aberrant hippocampal connectivity in unmedicated patients with schizophrenia and effects of antipsychotic medication: a longitudinal resting state functional MRI study. Schizophr Bull 42(4):1046\u20131055","journal-title":"Schizophr Bull"},{"issue":"2","key":"2007_CR21","first-page":"1","volume":"161","author":"AF Lehman","year":"2004","unstructured":"Lehman AF, Lieberman JA, Dixon LB, McGlashan TH, Miller AL, Perkins DO, Kreyenbuhl J (2004) Practice guideline for the treatment of patients with schizophrenia. Am J Psychiatry 161(2):1\u201356","journal-title":"Am J Psychiatry"},{"key":"2007_CR22","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1038\/nrd.2016.28","volume":"15","author":"MJ Millan","year":"2016","unstructured":"Millan MJ, Andrieux A, Bartzokis G, Cadenhead K, Dazzan P, Fusar-Poli P, Gallinat J, Giedd J, Grayson DR, Heinrichs M, Kahn R, Krebs MO, Leboyer M, Lewis D, Marin O, Marin P, Meyer-Lindenberg A, McGorry P, McGuire P, Owen MJ, Patterson P, Sawa A, Spedding M, Uhlhaas P, Vaccarino F, Wahlestedt C, Weinberger D (2016) Altering the course of schizophrenia: progress and perspectives. Nat Rev Drug Discov 15:485\u2013515","journal-title":"Nat Rev Drug Discov"},{"key":"2007_CR23","volume-title":"The rat brain in stereotaxic coordinates: hard cover edition","author":"G Paxinos","year":"2006","unstructured":"Paxinos G, Watson C (2006) The rat brain in stereotaxic coordinates: hard cover edition. Elsevier, Amsterdam"},{"issue":"1","key":"2007_CR24","first-page":"55","volume":"69","author":"G Rammes","year":"2008","unstructured":"Rammes G, Danysz W, Parsons CG (2008) Pharmacodynamics of memantine: an update. Curr Neuropharmacol 69(1):55\u201378","journal-title":"Curr Neuropharmacol"},{"issue":"1","key":"2007_CR25","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.neuron.2006.09.015","volume":"52","author":"CA Ross","year":"2006","unstructured":"Ross CA, Russell LM, Reading S, Pletnikov M, Coyle J (2006) Neurobiology of schizophrenia. Neuron 52(1):139\u2013153","journal-title":"Neuron"},{"issue":"1\u20132","key":"2007_CR26","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/0014-2999(94)90023-X","volume":"262","author":"R Spanagel","year":"1994","unstructured":"Spanagel R, Eilbacher B, Wilke R (1994) Memantine-induced dopamine release in the prefrontal cortex and striatum of the rat\u2014a pharmacokinetic microdialysis study. Eur J Pharmacol 262(1\u20132):21\u201326","journal-title":"Eur J Pharmacol"},{"key":"2007_CR27","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1146\/annurev-neuro-060909-153238","volume":"34","author":"G Turrigiano","year":"2011","unstructured":"Turrigiano G (2011) Too many cooks? Intrinsic and synaptic homeostatic mechanisms in cortical circuit refinement. Annu Rev Neurosci 34:89\u2013103","journal-title":"Annu Rev Neurosci"},{"issue":"15","key":"2007_CR28","first-page":"280516","volume":"7","author":"E Uribe","year":"2016","unstructured":"Uribe E (2016) Neuropsychological subtypes of schizophrenia and prefrontal circuits. Rev eNeurobiol 7(15):280516","journal-title":"Rev eNeurobiol"},{"issue":"21","key":"2007_CR29","first-page":"240918","volume":"9","author":"E Uribe","year":"2018","unstructured":"Uribe E, Torres M (2018) Neuropsychological screening for schizophrenia: a brief tool to assess subtypes of schizophrenia. Rev eNeurobiol 9(21):240918","journal-title":"Rev eNeurobiol"},{"key":"2007_CR30","first-page":"45","volume":"17","author":"E Uribe","year":"2010","unstructured":"Uribe E, Wix R (2010) Migracion Neuronal y esquizofrenia. Neurociencias en Colombia 17:45\u201360","journal-title":"Neurociencias en Colombia"},{"key":"2007_CR31","first-page":"310811","volume":"2","author":"E Uribe","year":"2011","unstructured":"Uribe E, Wix R (2011a) Epigenetic control of the GABAergic interneurons migration and NMDA receptor functioning in schizophrenia. eNeurobiologia 2:310811","journal-title":"eNeurobiologia"},{"issue":"3","key":"2007_CR32","first-page":"258","volume":"18","author":"E Uribe","year":"2011","unstructured":"Uribe E, Wix R (2011b) Synapticconnection and schizophrenia. Neurociencias en Colombia 18(3):258\u2013271","journal-title":"Neurociencias en Colombia"},{"key":"2007_CR33","doi-asserted-by":"publisher","first-page":"18","DOI":"10.5607\/en.2013.22.1.18","volume":"22","author":"E Uribe","year":"2013","unstructured":"Uribe E, Landaeta J, Wix R, Eblen-Zajjur A (2013) Memantine reverses social withdrawal induced by ketamine in rats. Exp Neurobiol 22:18\u201322","journal-title":"Exp Neurobiol"},{"issue":"6","key":"2007_CR34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.5607\/en.2016.25.6.328","volume":"25","author":"E Uribe","year":"2016","unstructured":"Uribe E, S\u00e1nchez-Mendoza E, Nieves N, Merchor G (2016) Neonatal administration of memantine enhances social cognition in adult rats subjected to early maternal deprivation. Exp Neurobiol 25(6):1\u20135","journal-title":"Exp Neurobiol"},{"key":"2007_CR35","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.psc.2007.04.010","volume":"30","author":"PJ Weiden","year":"2007","unstructured":"Weiden PJ, Buckley PF, Grody M (2007) Understanding and treating \u201cfirst-episode\u201d schizophrenia. Psychiatr Clin N Am 30:481\u2013510","journal-title":"Psychiatr Clin N Am"},{"issue":"1","key":"2007_CR36","doi-asserted-by":"publisher","first-page":"48","DOI":"10.9758\/cpn.2014.12.1.48","volume":"12","author":"R Wix","year":"2014","unstructured":"Wix R, Moreno X, Capote E, Gonz\u00e1lez G, Uribe E, Eblen-Zajjur A (2014) Drug treated schizophrenia, schizoaffective and bipolar disorder patients evaluated by qEEG absolute spectral power and mean frequency analysis. Clin Psychopharmacol Neurosci 12(1):48\u201353","journal-title":"Clin Psychopharmacol Neurosci"},{"key":"2007_CR37","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1007\/978-3-662-45758-0_243","volume":"16","author":"TU Woo","year":"2014","unstructured":"Woo TU (2014) Neurobiology of schizophrenia onset. Curr Top Behav Neurosci 16:267\u2013295","journal-title":"Curr Top Behav Neurosci"}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-019-02007-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00702-019-02007-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-019-02007-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T23:31:40Z","timestamp":1588289500000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00702-019-02007-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,2]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["2007"],"URL":"https:\/\/doi.org\/10.1007\/s00702-019-02007-x","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,2]]},"assertion":[{"value":"23 July 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 April 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 May 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}