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Moreover, adults with elevated ADHD symptoms report increased perceived stress. Despite this, it has rarely been examined whether and how child and maternal ADHD symptoms may affect maternal perceived stress and the stress-sensitive hypothalamic\u2013pituitary\u2013adrenal axis. This study therefore investigated the possible impact of child and maternal ADHD symptoms on mothers' perceived chronic stress and hair cortisol concentration (HCC), while simultaneously considering the effects of child oppositional defiant\/conduct disorder (ODD\/CD) and maternal depressive symptomatology. In total, 124 mothers (35.96\u2009\u00b1\u20095.21\u00a0years) of preschool children were included. Maternal perceived stress, ADHD and depressive symptoms were assessed using self-report measures. Child ADHD symptoms were assessed using an interview and questionnaires completed by mothers and teachers. Additionally, mothers provided information about their children\u2019s ODD\/CD symptoms. Hair samples were taken from mothers to assess HCC. Child and maternal ADHD, child ODD\/CD, and maternal depressive symptoms accounted for 50% of the variance in perceived chronic stress (<jats:italic>F<\/jats:italic>(4, 119)\u2009=\u200930.24; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), with only maternal ADHD (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.52, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) and depressive symptoms (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.49, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) being uniquely significant. Maternal ADHD symptoms did not moderate the relationship between child ADHD symptoms and maternal perceived chronic stress (<jats:italic>b<\/jats:italic>\u2009=\u2009\u2212\u20090.01; SE<jats:italic> b<\/jats:italic>\u2009=\u20090.17; <jats:italic>t<\/jats:italic>(5, 118)\u2009=\u2009\u2212\u20090.05; <jats:italic>p<\/jats:italic>\u2009=\u20090.96). Mother\u2019s age became the only significant predictor of maternal HCC (<jats:italic>\u03b2<\/jats:italic>\u2009=\u20090.29; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01). Based on these findings, practitioners are advised to be aware of and take into account possible maternal ADHD and depressive symptomatology and perceived chronic stress when treating children diagnosed with ADHD.<\/jats:p>","DOI":"10.1007\/s00702-021-02377-1","type":"journal-article","created":{"date-parts":[[2021,7,6]],"date-time":"2021-07-06T10:05:42Z","timestamp":1625565942000},"page":"1311-1324","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["The impact of preschool child and maternal attention-deficit\/hyperactivity disorder (ADHD) symptoms on mothers\u2019 perceived chronic stress and hair cortisol"],"prefix":"10.1007","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3435-7935","authenticated-orcid":false,"given":"Anna","family":"Sz\u00e9p","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Skoluda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Schlo\u00df","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja","family":"Becker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Pauli-Pott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urs M.","family":"Nater","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,6]]},"reference":[{"key":"2377_CR1","volume-title":"Parenting stress index","author":"RR Abidin","year":"1995","unstructured":"Abidin RR (1995) Parenting stress index. 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