{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:12:48Z","timestamp":1791216768480,"version":"4.1.0"},"reference-count":77,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T00:00:00Z","timestamp":1736553600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2022\/05775-0"],"award-info":[{"award-number":["2022\/05775-0"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["001"],"award-info":[{"award-number":["001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1007\/s00702-024-02872-1","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T11:28:39Z","timestamp":1736594919000},"page":"537-546","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["A new vision of the role of the cerebellum in pain processing"],"prefix":"10.1007","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7077-0161","authenticated-orcid":false,"given":"Jos\u00e9 M\u00e1rio","family":"Prati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Carolyna","family":"Gianloren\u00e7o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,1,11]]},"reference":[{"issue":"3","key":"2872_CR1","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1152\/jn.1987.58.3.480","volume":"58","author":"WS Ammons","year":"1987","unstructured":"Ammons WS (1987) Characteristics of spinoreticular and spinothalamic neurons with renal input. J Neurophysiol Sep 58(3):480\u2013495. https:\/\/doi.org\/10.1152\/jn.1987.58.3.480","journal-title":"J Neurophysiol Sep"},{"issue":"2","key":"2872_CR2","doi-asserted-by":"publisher","first-page":"e0193413","DOI":"10.1371\/journal.pone.0193413","volume":"13","author":"JK Baarb\u00e9","year":"2018","unstructured":"Baarb\u00e9 JK, Yielder P, Haavik H, Holmes MWR, Murphy BA (2018) Subclinical recurrent Neck Pain and its treatment impacts Motor Training-Induced plasticity of the Cerebellum and Motor Cortex. PLoS ONE 13(2):e0193413. https:\/\/doi.org\/10.1371\/journal.pone.0193413","journal-title":"PLoS ONE"},{"issue":"2","key":"2872_CR3","doi-asserted-by":"publisher","first-page":"e310","DOI":"10.1097\/j.pain.0000000000002287","volume":"163","author":"A Barke","year":"2022","unstructured":"Barke A, Korwisi B, Jakob R, Konstanjsek N, Rief W, Treede RD (2022) Classification of chronic pain for the International classification of diseases (ICD-11): results of the 2017 international World Health Organization field testing. PAIN Feb 163(2):e310. https:\/\/doi.org\/10.1097\/j.pain.0000000000002287","journal-title":"PAIN Feb"},{"issue":"5","key":"2872_CR4","doi-asserted-by":"publisher","first-page":"719","DOI":"10.1002\/ejp.2212","volume":"28","author":"H Basedau","year":"2024","unstructured":"Basedau H, May A, Mehnert J (2024) Cerebellar Somatotopy of the trigemino-cervical complex during Nociception. Eur J Pain 28(5):719\u2013728. https:\/\/doi.org\/10.1002\/ejp.2212","journal-title":"Eur J Pain"},{"issue":"4","key":"2872_CR5","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1016\/j.neuroimage.2012.03.044","volume":"61","author":"O Baumann","year":"2012","unstructured":"Baumann O, Mattingley JB (2012) Functional topography of primary emotion Processing in the human cerebellum. NeuroImage 61(4):805\u2013811. https:\/\/doi.org\/10.1016\/j.neuroimage.2012.03.044","journal-title":"NeuroImage"},{"issue":"6","key":"2872_CR6","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1111\/jon.12759","volume":"30","author":"MS Bermo","year":"2020","unstructured":"Bermo MS, Zacharias C, Patterson D, Wilson A, Sharar S, Minoshima S, Hoffman H, Lewis DH (2020) The role of the Cerebellum in Pain Perception: a brain SPECT perfusion study in patients with burn injuries. J Neuroimaging 30(6):815\u2013821. https:\/\/doi.org\/10.1111\/jon.12759","journal-title":"J Neuroimaging"},{"key":"2872_CR7","doi-asserted-by":"publisher","unstructured":"Bhatt RR, Haddad E, Zhu AH, Thompson PM, Gupta A, Emeran, Mayer A, Jahanshad N (2024) Mapping Brain structure variability in Chronic Pain: the role of Widespreadness and Pain Type and its mediating relationship with suicide attempt. Biological Psychiatry, BPS 95\/5Mood disorder biomarkers. 95(5):473\u2013481. https:\/\/doi.org\/10.1016\/j.biopsych.2023.07.016","DOI":"10.1016\/j.biopsych.2023.07.016"},{"issue":"8","key":"2872_CR8","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1002\/ar.23587","volume":"300","author":"P Boadas-Vaello","year":"2017","unstructured":"Boadas-Vaello P, Homs J, Reina F, Carrera A, Verd\u00fa E (2017) Neuroplasticity of Supraspinal Structures Associated with Pathological Pain. Anat Rec 300(8):1481\u20131501. https:\/\/doi.org\/10.1002\/ar.23587","journal-title":"Anat Rec"},{"issue":"5","key":"2872_CR9","doi-asserted-by":"publisher","first-page":"597","DOI":"10.3233\/RNN-140453","volume":"33","author":"T Bocci","year":"2015","unstructured":"Bocci T, Santarcangelo E, Vannini B, Tozini A, Carli G, Ferrucci R, Priori A, Valeriani M, Sartucci F (2015) Cerebellar Direct Current Stimulation modulates Pain Perception in humans. Restor Neurol Neurosci 33(5):597\u2013609. https:\/\/doi.org\/10.3233\/RNN-140453","journal-title":"Restor Neurol Neurosci"},{"key":"2872_CR10","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s12311-019-01020-w","volume":"18","author":"T Bocci","year":"2019","unstructured":"Bocci T, De Carolis G, Ferrucci R, Paroli M, Mansani F, Priori A, Valeriani M, Sartucci F (2019) Cerebellar Transcranial Direct Current Stimulation (ctDCS) ameliorates Phantom Limb Pain and Non-painfull Phantom Limb sensations. Cerebellum 18:527\u2013535. https:\/\/doi.org\/10.1007\/s12311-019-01020-w","journal-title":"Cerebellum"},{"key":"2872_CR11","doi-asserted-by":"publisher","unstructured":"Bordeleau M, Vincenot M, Lefevre S, Duport A, Seggio L, Breton T, Lelard T et al (2022) Treatments for Kinesiophobia in people with Chronic Pain: a scoping review. Front Behav Neurosci 16(September). https:\/\/doi.org\/10.3389\/fnbeh.2022.933483","DOI":"10.3389\/fnbeh.2022.933483"},{"issue":"3","key":"2872_CR12","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1007\/s12311-008-0011-6","volume":"7","author":"D Borsook","year":"2008","unstructured":"Borsook D, Moulton EA, Tully S, Schmahmann JD, Becerra L (2008) Human cerebellar responses to Brush and Heat Stimuli in Healthy and Neuropathic Pain subjects. Cerebellum 7(3):252\u2013272. https:\/\/doi.org\/10.1007\/s12311-008-0011-6","journal-title":"Cerebellum"},{"issue":"2","key":"2872_CR13","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/0006-8993(90)90179-f","volume":"19","author":"R Burstein","year":"1990","unstructured":"Burstein R, Dado RJ, Giesler GJ (1990) The cells of origin of the spinothalamic tract of the rat: a quantitative reexamination. Brain Res Mar 19(2):329\u2013337. https:\/\/doi.org\/10.1016\/0006-8993(90)90179-f","journal-title":"Brain Res Mar"},{"key":"2872_CR14","doi-asserted-by":"publisher","unstructured":"Cacciola A, Bertino S, Basile GA, Di Mauro D, Calamuneri A, Chillemi G et al (2019) Mapping the structural connectivity between the periaqueductal gray and the cerebellum in humans. Brain Struct Funct. Jul 1;224(6):2153\u201365. https:\/\/doi.org\/10.1007\/s00429-019-01893-x","DOI":"10.1007\/s00429-019-01893-x"},{"issue":"1","key":"2872_CR15","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1002\/cne.901820110","volume":"182","author":"E Carstens","year":"1978","unstructured":"Carstens E, Trevino DL (1978) Laminar origins of spinothalamic projections in the cat as determined by the retrograde transport of horseradish peroxidase. J Comp Neurol 182(1):151\u2013165. https:\/\/doi.org\/10.1002\/cne.901820110","journal-title":"J Comp Neurol"},{"issue":"5","key":"2872_CR16","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1007\/s12311-018-0938-1","volume":"17","author":"S \u00c7avdar","year":"2018","unstructured":"\u00c7avdar S, \u00d6zgur M, Kuvvet Y, Bay HH (2018) The Cerebello-Hypothalamic and Hypothalamo-Cerebellar Pathways via Superior and Middle Cerebellar Peduncle in the rat. Cerebellum 17(5):517\u2013524. https:\/\/doi.org\/10.1007\/s12311-018-0938-1","journal-title":"Cerebellum"},{"key":"2872_CR17","doi-asserted-by":"publisher","first-page":"110794","DOI":"10.1016\/j.brainresbull.2023.110794","volume":"1","author":"Y Chen","year":"2023","unstructured":"Chen Y, Yang Y, Gong Z, Kang Y, Zhang Y, Chen H et al (2023) Altered effective connectivity from cerebellum to motor cortex in chronic low back pain: a multivariate pattern analysis and spectral dynamic causal modeling study. Brain Res Bull Nov 1:204:110794. https:\/\/doi.org\/10.1016\/j.brainresbull.2023.110794","journal-title":"Brain Res Bull Nov"},{"issue":"2","key":"2872_CR19","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1007\/s12311-016-0832-7","volume":"16","author":"J Claassen","year":"2017","unstructured":"Claassen J, Labrenz F, Ernst TM, Icenhour A, Langhorst J, Forsting M, Timmann D, Elsenbruch S (2017) Altered cerebellar activity in Visceral Pain-related fear conditioning in irritable bowel syndrome. Cerebellum 16(2):508\u2013517. https:\/\/doi.org\/10.1007\/s12311-016-0832-7","journal-title":"Cerebellum"},{"issue":"2","key":"2872_CR18","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1136\/jnnp-2019-321025","volume":"91","author":"J Claassen","year":"2020","unstructured":"Claassen J, Koenen LR, Ernst TM, Labrenz F, Theysohn N, Forsting M, Bingel U, Timmann D, Elsenbruch S (2020) Cerebellum is more concerned about visceral than somatic Pain. J Neurol Neurosurg Psychiatry 91(2):218\u2013219. https:\/\/doi.org\/10.1136\/jnnp-2019-321025","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"1","key":"2872_CR20","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1097\/j.pain.0000000000000337","volume":"157","author":"SA Coombes","year":"2016","unstructured":"Coombes SA, Misra G (2016) Pain and Motor Processing in the human cerebellum. Pain 157(1):117. https:\/\/doi.org\/10.1097\/j.pain.0000000000000337","journal-title":"Pain"},{"issue":"1","key":"2872_CR21","doi-asserted-by":"publisher","first-page":"63","DOI":"10.3390\/biomedicines11010063","volume":"11","author":"Y Cui","year":"2023","unstructured":"Cui Y, Neyama H, Hu D, Huang T, Hayashinaka E, Wada Y, Watanabe Y (2023) FDG PET Imaging of the Pain Matrix in Neuropathic Pain Model rats. Biomedicines 11(1):63. https:\/\/doi.org\/10.3390\/biomedicines11010063","journal-title":"Biomedicines"},{"issue":"10","key":"2872_CR22","doi-asserted-by":"publisher","first-page":"1881","DOI":"10.1016\/j.cub.2020.03.028","volume":"30","author":"AM D\u2019Mello","year":"2020","unstructured":"D\u2019Mello AM, Gabrieli JDE, Nee DE (2020) Evidence for hierarchical cognitive control in the human cerebellum. Curr Biol 30(10):1881\u20131892e3. https:\/\/doi.org\/10.1016\/j.cub.2020.03.028","journal-title":"Curr Biol"},{"key":"2872_CR23","doi-asserted-by":"publisher","unstructured":"Diano M, D\u2019Agata F, Cauda F, Costa T, Geda E, Sacco K et al (2016) Cerebellar clustering and functional Connectivity during Pain Processing. Cerebellum Jun 1153(343\u201356). https:\/\/doi.org\/10.1007\/s12311-015-0706-4","DOI":"10.1007\/s12311-015-0706-4"},{"key":"2872_CR24","doi-asserted-by":"publisher","unstructured":"Doetsch GS (1997) Progressive changes in cutaneous trigger zones for sensation referred to a phantom hand: a case report and review with implications for cortical reorganization. Somatosensory & Motor Research Jan 1;14(1):6\u201316. https:\/\/doi.org\/10.1080\/08990229771178","DOI":"10.1080\/08990229771178"},{"issue":"4","key":"2872_CR25","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1111\/j.2044-8260.1994.tb01150.x","volume":"33","author":"C Eccleston","year":"1994","unstructured":"Eccleston C (1994) Chronic Pain and attention: a Cognitive Approach. Br J Clin Psychol 33(4):535\u2013547. https:\/\/doi.org\/10.1111\/j.2044-8260.1994.tb01150.x","journal-title":"Br J Clin Psychol"},{"issue":"1","key":"2872_CR26","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1113\/jphysiol.1987.sp016549","volume":"386","author":"CF Ekerot","year":"1987","unstructured":"Ekerot CF, Gustavsson P, Oscarsson O, Schouenborg J (1987a) Climbing fibres projecting to cat cerebellar anterior lobe activated by cutaneous A and C fibres. J Physiol 386(1):529\u2013538. https:\/\/doi.org\/10.1113\/jphysiol.1987.sp016549","journal-title":"J Physiol"},{"issue":"1","key":"2872_CR27","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1113\/jphysiol.1987.sp016550","volume":"386","author":"CF Ekerot","year":"1987","unstructured":"Ekerot CF, Oscarsson O, Schouenborg J (1987b) Stimulation of cat cutaneous nociceptive C fibres causing tonic and synchronous activity in climbing fibres. J Physiol 386(1):539\u2013546. https:\/\/doi.org\/10.1113\/jphysiol.1987.sp016550","journal-title":"J Physiol"},{"issue":"5","key":"2872_CR28","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1123\/jsr.2021-0236","volume":"31","author":"KDB Foss","year":"2022","unstructured":"Foss KDB, Slutsky-Ganesh AB, Diekfuss JA, Grooms DR, Simon JE, Schneider DK, Jayanthi N et al (2022) Brain activity during experimental knee Pain and its relationship with Kinesiophobia in patients with Patellofemoral Pain: a preliminary functional magnetic resonance Imaging Investigation. J Sport Rehabilitation 31(5):589\u2013598. https:\/\/doi.org\/10.1123\/jsr.2021-0236","journal-title":"J Sport Rehabilitation"},{"issue":"1","key":"2872_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s12311-019-01083-9","volume":"19","author":"X Guell","year":"2020","unstructured":"Guell X, Schmahmann JD (2020) Cerebellar functional anatomy: a didactic Summary based on human fMRI evidence. Cerebellum 19(1):1\u20135. https:\/\/doi.org\/10.1007\/s12311-019-01083-9","journal-title":"Cerebellum"},{"key":"2872_CR30","doi-asserted-by":"publisher","unstructured":"Han JS, Neugebauer V (2004) Synaptic Plasticity in the Amygdala in a Visceral Pain Model in Rats. Neuroscience Letters, Festschrift dedicated to Prof. Manfred Zimmermann on the occasion of his 70th birthday, 361 (1): 254\u201357. https:\/\/doi.org\/10.1016\/j.neulet.2003.12.027","DOI":"10.1016\/j.neulet.2003.12.027"},{"issue":"3","key":"2872_CR31","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1016\/S0304-3940(02)01164-3","volume":"335","author":"C Helmchen","year":"2003","unstructured":"Helmchen C, Mohr C, Erdmann C, Petersen D, Nitschke MF (2003) Differential Cerebellar Activation related to Perceived Pain Intensity during noxious thermal stimulation in humans: a functional magnetic resonance imaging study. Neurosci Lett 335(3):202\u2013206. https:\/\/doi.org\/10.1016\/S0304-3940(02)01164-3","journal-title":"Neurosci Lett"},{"issue":"2","key":"2872_CR32","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/0304-3959(95)00129-8","volume":"64","author":"JC Hsieh","year":"1996","unstructured":"Hsieh JC, St\u00e5hle-B\u00e4ckdahl M, H\u00e4germark O, Stone-Elander S, Rosenquist G, Ingvar M (1996) Traumatic nociceptive Pain activates the Hypothalamus and the Periaqueductal Gray: a Positron Emission Tomography Study. Pain 64(2):303. https:\/\/doi.org\/10.1016\/0304-3959(95)00129-8","journal-title":"Pain"},{"issue":"2","key":"2872_CR33","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/S0304-3940(01)01952-8","volume":"307","author":"JC Hsieh","year":"2001","unstructured":"Hsieh JC, Tu CH, Chen FP, Chen MC, Yeh TC, Cheng HC, Wu YT, Liu RS, Ho LT (2001) Activation of the Hypothalamus characterizes the acupuncture stimulation at the Analgesic Point in Human: a Positron Emission Tomography Study. Neurosci Lett 307(2):105\u2013108. https:\/\/doi.org\/10.1016\/S0304-3940(01)01952-8","journal-title":"Neurosci Lett"},{"key":"2872_CR34","doi-asserted-by":"publisher","unstructured":"Hubbard CS, Karpowicz JM, Furman AJ, Silva JT, Seminowicz DA, Traub RJ (2016) Estrogen-dependent visceral hypersensitivity following stress in rats. An fMRI study Mol Pain 12:1744806916654145. https:\/\/doi.org\/10.1177\/1744806916654145","DOI":"10.1177\/1744806916654145"},{"issue":"1","key":"2872_CR36","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/0306-4522(89)90229-7","volume":"28","author":"JL Hylden","year":"1989","unstructured":"Hylden JL, Anton F, Nahin RL (1989) Spinal lamina I projection neurons in the rat: collateral innervation of parabrachial area and thalamus. Neuroscience 28(1):27\u201337. https:\/\/doi.org\/10.1016\/0306-4522(89)90229-7","journal-title":"Neuroscience"},{"issue":"2","key":"2872_CR37","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1016\/0006-8993(92)90717-N","volume":"581","author":"W Jie","year":"1992","unstructured":"Jie W, Pei-Xi C (1992) Discharge response of cerebellar Purkinje cells to stimulation of C-fiber in cat saphenous nerve. Brain Res 581(2):269\u2013272. https:\/\/doi.org\/10.1016\/0006-8993(92)90717-N","journal-title":"Brain Res"},{"key":"2872_CR38","doi-asserted-by":"publisher","unstructured":"Kim H, Kim J, Loggia ML, Cahalan C, Garcia RG, Vangel MG, Wasan AD, Edwards RR, Napadow V (2015a) Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks. NeuroImage: clinical 7. January667\u2013677. https:\/\/doi.org\/10.1016\/j.nicl.2015.02.022","DOI":"10.1016\/j.nicl.2015.02.022"},{"issue":"6","key":"2872_CR39","doi-asserted-by":"publisher","first-page":"1051","DOI":"10.1007\/s00701-015-2415-7","volume":"157","author":"J Kim","year":"2015","unstructured":"Kim J, Shin J, Oh JH, Jung HH, Kim YB, Cho ZH, Chang JW (2015b) Longitudinal FDG microPET imaging of Neuropathic Pain: does cerebellar activity correlate with neuropathic Pain Development in a rat model? Acta Neurochir 157(6):1051\u20131057. https:\/\/doi.org\/10.1007\/s00701-015-2415-7","journal-title":"Acta Neurochir"},{"key":"2872_CR40","doi-asserted-by":"publisher","unstructured":"Kim J, Ryu SB, Lee SE, Shin J, Jung HH, Kim SJ, Kim KH, Chag JH (2016) Motor cortex stimulation and neuropathic pain: how does motor cortex stimulation affect pain-signaling pathways? J Neurosurg 124(3). https:\/\/doi.org\/10.3171\/2015.1.JNS14891","DOI":"10.3171\/2015.1.JNS14891"},{"issue":"8","key":"2872_CR41","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1038\/s41593-019-0436-x","volume":"22","author":"M King","year":"2019","unstructured":"King M, Hernandez-Castillo CR, Poldrack RA, Ivry RB, Diedrichsen J (2019) Functional boundaries in the human cerebellum revealed by a Multi-domain Task Battery. Nat Neurosci 22(8):1371\u20131378. https:\/\/doi.org\/10.1038\/s41593-019-0436-x","journal-title":"Nat Neurosci"},{"issue":"1","key":"2872_CR42","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/0006-8993(83)91111-3","volume":"22","author":"Y Lamour","year":"1983","unstructured":"Lamour Y, Guilbaud G, Willer JC (1983) Altered properties and laminar distribution of neuronal responses to peripheral stimulation in the Sml cortex of the arthritic rat. Brain Res Aug 22(1):183\u2013187. https:\/\/doi.org\/10.1016\/0006-8993(83)91111-3","journal-title":"Brain Res Aug"},{"issue":"2","key":"2872_CR43","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1002\/cne.901860203","volume":"15","author":"AR Light","year":"1979","unstructured":"Light AR, Perl ER (1979) Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers. J Comp Neurol Jul 15(2):133\u2013150. https:\/\/doi.org\/10.1002\/cne.901860203","journal-title":"J Comp Neurol Jul"},{"key":"2872_CR44","doi-asserted-by":"publisher","first-page":"111773","DOI":"10.1016\/j.exger.2022.111773","volume":"15","author":"AL Lipat","year":"2022","unstructured":"Lipat AL, Clark DJ, Hass CJ, Cruz-Almeida Y (2022) Gait subgroups among older adults with chronic pain differ in cerebellum and basal ganglia gray matter volumes. Experimental Gerontol Jun 15:163:111773. https:\/\/doi.org\/10.1016\/j.exger.2022.111773","journal-title":"Experimental Gerontol Jun"},{"issue":"9","key":"2872_CR45","doi-asserted-by":"publisher","first-page":"5028","DOI":"10.3390\/ijms22095028","volume":"10","author":"B Lottering","year":"2021","unstructured":"Lottering B, Lin YW (2021) TRPV1 responses in the Cerebellum lobules VI, VII, VIII using Electroacupuncture Treatment for Chronic Pain and Depression Comorbidity in a murine model. Int J Mol Sci May 10(9):5028. https:\/\/doi.org\/10.3390\/ijms22095028","journal-title":"Int J Mol Sci May"},{"issue":"3","key":"2872_CR46","doi-asserted-by":"publisher","first-page":"241","DOI":"10.1038\/nrn1347","volume":"5","author":"E Manni","year":"2004","unstructured":"Manni E, Petrosini L (2004) A Century of Cerebellar Somatotopy: a debated representation. Nat Rev Neurosci 5(3):241\u2013249. https:\/\/doi.org\/10.1038\/nrn1347","journal-title":"Nat Rev Neurosci"},{"issue":"1","key":"2872_CR47","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1002\/cne.902970106","volume":"297","author":"CA Mason","year":"1990","unstructured":"Mason CA, Christakos S, Catalano SM (1990) Early climbing fiber interactions with Purkinje cells in the postnatal mouse cerebellum. J Comp Neurol 297(1):77\u201390","journal-title":"J Comp Neurol"},{"issue":"4","key":"2872_CR48","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1177\/0271678X17722109","volume":"39","author":"J Mehnert","year":"2019","unstructured":"Mehnert J, May A (2019) Functional and structural alterations in the Migraine Cerebellum. J Cereb Blood Flow Metabolism 39(4):730\u2013739. https:\/\/doi.org\/10.1177\/0271678X17722109","journal-title":"J Cereb Blood Flow Metabolism"},{"key":"2872_CR49","unstructured":"Melzack R, Casey K (1968) Sensory, Motivational, and Central Control Determinants of Pain. Kenshalo DR, Editor. The Skin Senses: Proceedings. Springfield (Illinois): Charles C. Thomas, January, 423\u201343"},{"issue":"3","key":"2872_CR50","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1080\/17470218.2011.626865","volume":"65","author":"DJ Moore","year":"2012","unstructured":"Moore DJ, Keogh E, Eccleston C (2012) The Interruptive Effect of Pain on attention. Q J Experimental Psychol 65(3):565\u2013586. https:\/\/doi.org\/10.1080\/17470218.2011.626865","journal-title":"Q J Experimental Psychol"},{"issue":"1","key":"2872_CR51","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.brainresrev.2010.05.005","volume":"65","author":"EA Moulton","year":"2010","unstructured":"Moulton EA, Schmahmann JD, Becerra L, Borsook D (2010) The cerebellum and pain: Passive integrator or active participator? Brain Res Rev 65(1):14\u201327. https:\/\/doi.org\/10.1016\/j.brainresrev.2010.05.005","journal-title":"Brain Res Rev"},{"key":"2872_CR52","doi-asserted-by":"publisher","first-page":"444","DOI":"10.1016\/j.rvsc.2017.07.024","volume":"114","author":"D Nagakubo","year":"2017","unstructured":"Nagakubo D, Hamamoto Y, Hasegawa D, Kamata M, Iizuka T, Muta K, Fujita N, Nakagawa T, Nishimura R (2017) Functional MRI-based identification of brain regions activated by mechanical noxious stimulation and modulatory effect of remifentanil in cats. Res Vet Sci 114:444\u2013449. https:\/\/doi.org\/10.1016\/j.rvsc.2017.07.024","journal-title":"Res Vet Sci"},{"issue":"4","key":"2872_CR53","doi-asserted-by":"publisher","first-page":"e745","DOI":"10.1097\/PR9.0000000000000745","volume":"4","author":"V Napadow","year":"2019","unstructured":"Napadow V, Sclocco R, Henderson LA (2019) Brainstem neuroimaging of Nociception and Pain circuitries. PAIN Rep 4(4):e745. https:\/\/doi.org\/10.1097\/PR9.0000000000000745","journal-title":"PAIN Rep"},{"issue":"2","key":"2872_CR54","doi-asserted-by":"publisher","first-page":"195","DOI":"10.3233\/NRE-161404","volume":"40","author":"M Pereira","year":"2017","unstructured":"Pereira M, Rafiq B, Chowdhury E, Babayev J, Boo H, Metwaly R, Sandilya P, Chusid E, Battaglia F (2017) Anodal cerebellar tDCS modulates lower extremity pain perception. NeuroRehabilitation 40(2):195\u2013200. https:\/\/doi.org\/10.3233\/NRE-161404","journal-title":"NeuroRehabilitation"},{"issue":"46","key":"2872_CR55","doi-asserted-by":"publisher","first-page":"12067","DOI":"10.1523\/JNEUROSCI.2905-06.2006","volume":"26","author":"A Pjipers","year":"2006","unstructured":"Pjipers A, Apps R, Pardoe J et al (2006) Precise spatial relationships between Mossy fibers and climbing fibers in rat cerebellar cortical zones. J Neurosci 26(46):12067\u201312080. https:\/\/doi.org\/10.1523\/JNEUROSCI.2905-06.2006","journal-title":"J Neurosci"},{"issue":"16","key":"2872_CR56","doi-asserted-by":"publisher","first-page":"3345","DOI":"10.1113\/jphysiol.2013.270280","volume":"592","author":"A Priori","year":"2014","unstructured":"Priori A, Ciocca M, Parazzini M, Vergari M, Ferrucci R (2014) Transcranial cerebellar direct current stimulation and transcutaneous spinal cord direct current stimulation as innovative tools for neuroscientists. J Physiol 592(16):3345\u20133369. https:\/\/doi.org\/10.1113\/jphysiol.2013.270280","journal-title":"J Physiol"},{"issue":"1","key":"2872_CR57","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1186\/s10194-019-1045-5","volume":"20","author":"Z Qin","year":"2019","unstructured":"Qin Z, He XW, Zhang J, Xu S, Li GF, Su J, Shi YH et al (2019) Structural changes of Cerebellum and Brainstem in Migraine without Aura. J Headache Pain 20(1):93. https:\/\/doi.org\/10.1186\/s10194-019-1045-5","journal-title":"J Headache Pain"},{"issue":"9","key":"2872_CR58","doi-asserted-by":"publisher","first-page":"1976","DOI":"10.1097\/j.pain.0000000000001939","volume":"161","author":"SN Raja","year":"2020","unstructured":"Raja SN, Carr DB, Cohen M, Finnerup NB, Flor H, Gibson S, Keefe FJ, Mogil JS, Ringkamp M, Sluka KA, Song XJ, Stevens B, Sullivan MD, Tutelman PR, Ushida T, Vader K (2020) The revised International Association for the study of Pain definition of pain: concepts, challenges, and compromises. Pain 161(9):1976\u20131982. https:\/\/doi.org\/10.1097\/j.pain.0000000000001939","journal-title":"Pain"},{"issue":"5","key":"2872_CR59","doi-asserted-by":"publisher","first-page":"794","DOI":"10.1080\/10790268.2020.1786321","volume":"44","author":"EJ Richardson","year":"2021","unstructured":"Richardson EJ, Deutsch G, Deshpande HD, Richards JS (2021) Differences in resting cerebellar and prefrontal cortical blood Flow in spinal cord Injury-Related Neuropathic Pain: a brief report. J Spinal Cord Med 44(5):794\u2013799. https:\/\/doi.org\/10.1080\/10790268.2020.1786321","journal-title":"J Spinal Cord Med"},{"issue":"2","key":"2872_CR60","doi-asserted-by":"publisher","first-page":"194","DOI":"10.1007\/s12311-012-0413-3","volume":"12","author":"C Rosenberger","year":"2013","unstructured":"Rosenberger C, Th\u00fcrling M, Forsting M, Elsenbruch S, Timmann D, Gizewski ER (2013) Contributions of the Cerebellum to Disturbed Central Processing of visceral stimuli in irritable bowel syndrome. Cerebellum 12(2):194\u2013198. https:\/\/doi.org\/10.1007\/s12311-012-0413-3","journal-title":"Cerebellum"},{"issue":"7","key":"2872_CR61","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1016\/j.pain.2014.04.006","volume":"155","author":"R Ruscheweyh","year":"2014","unstructured":"Ruscheweyh R, K\u00fchnel M, Filippopulos F, Blum B, Eggert T, Straube A (2014) Altered Experimental Pain Perception after cerebellar infarction. Pain 155(7):1303\u20131312. https:\/\/doi.org\/10.1016\/j.pain.2014.04.006","journal-title":"Pain"},{"key":"2872_CR62","doi-asserted-by":"publisher","unstructured":"Saab CY, Willis WD (2003) The cerebellum: organization, functions and its role in nociception. Brain Research Reviews Apr 1;42(1):85\u201395. https:\/\/doi.org\/10.1016\/S0165-0173(03)00151-6","DOI":"10.1016\/S0165-0173(03)00151-6"},{"issue":"4","key":"2872_CR63","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1097\/j.pain.0000000000000830","volume":"158","author":"KE Sadler","year":"2017","unstructured":"Sadler KE, McQuaid NA, Cox AC, Behun MN, Trouten AM, Kolber BJ (2017) Divergent functions of the Left and Right Central Amygdala in Visceral Nociception. Pain 158(4):747. https:\/\/doi.org\/10.1097\/j.pain.0000000000000830","journal-title":"Pain"},{"issue":"1","key":"2872_CR64","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1186\/s41747-023-00378-1","volume":"7","author":"V Sanchis-Alfonso","year":"2023","unstructured":"Sanchis-Alfonso V, Beser-Robles M, Ten-Esteve A, Ram\u00edrez-Fuentes C, Alberich-Bayarri A, Espert R, Garc\u00eda-Larrea L, Mart\u00ed-Bonmat\u00ed L (2023) Brain Network Functional Connectivity Changes in patients with anterior knee Pain: a resting-state fMRI exploratory study. Eur Radiol Experimental 7(1):60. https:\/\/doi.org\/10.1186\/s41747-023-00378-1","journal-title":"Eur Radiol Experimental"},{"issue":"688 January","key":"2872_CR65","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.neulet.2018.07.005","volume":"The Cerebellum","author":"JD Schmahmann","year":"2019","unstructured":"Schmahmann JD (2019) The Cerebellum and Cognition. Neurosci Lett The Cerebellum in Health and Disease(688 January):62\u201375. https:\/\/doi.org\/10.1016\/j.neulet.2018.07.005","journal-title":"Neurosci Lett"},{"issue":"3","key":"2872_CR66","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1006\/nimg.1999.0459","volume":"10","author":"JD Schmahmann","year":"1999","unstructured":"Schmahmann JD, Doyon J, McDonald D et al (1999) Three-dimensional MRI Atlas of the human cerebellum in Proportional Stereotaxic Space. NeuroImage 10(3):233\u2013260. https:\/\/doi.org\/10.1006\/nimg.1999.0459","journal-title":"NeuroImage"},{"key":"2872_CR67","doi-asserted-by":"publisher","unstructured":"Siegel P, Wepsic JG (1974) Alteration of nociception by stimulation of cerebellar structures in the monkey. Physiology & Behavior. Aug 1;13(2):189\u201394. https:\/\/doi.org\/10.1016\/0031-9384(74)90033-X","DOI":"10.1016\/0031-9384(74)90033-X"},{"issue":"2","key":"2872_CR68","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1002\/acn3.709","volume":"6","author":"KE Silva","year":"2019","unstructured":"Silva KE, Rosner J, Ullrich NJ, Chordas C, Manley PE, Moulton EA (2019) Pain Affect disrupted in children with posterior cerebellar Tumor Resection. Ann Clin Transl Neurol 6(2):344\u2013354. https:\/\/doi.org\/10.1002\/acn3.709","journal-title":"Ann Clin Transl Neurol"},{"issue":"5661","key":"2872_CR69","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1126\/science.1093535","volume":"303","author":"T Singer","year":"2004","unstructured":"Singer T, Seymour B, O\u2019Doherty et al (2004) Empathy for Pain involves the affective but not sensory components of Pain. Science 303(5661):1157\u20131162. https:\/\/doi.org\/10.1126\/science.1093535","journal-title":"Science"},{"issue":"9","key":"2872_CR71","doi-asserted-by":"publisher","first-page":"2433","DOI":"10.1046\/j.1460-9568.2003.02981.x","volume":"18","author":"RC Spike","year":"2003","unstructured":"Spike RC, Pusk\u00e1r Z, Andrew D, Todd AJ (2003) A quantitative and morphological study of projection neurons in lamina I of the rat lumbar spinal cord. Eur J Neurosci Nov 18(9):2433\u20132448. https:\/\/doi.org\/10.1046\/j.1460-9568.2003.02981.x","journal-title":"Eur J Neurosci Nov"},{"key":"2872_CR72","doi-asserted-by":"publisher","unstructured":"Stacheneder R, Alt L, Straube A, Ruscheweyh R (2023) Effects of Transcranial Direct Current Stimulation (t-DCS) of the Cerebellum on Pain Perception and Endogenous Pain Modulation: a Randomized, Monocentric, Double-Blind, Sham-Controlled Crossover Study. The Cerebellum 22, 1234\u20131242 (2023). https:\/\/doi.org\/10.1007\/s12311-022-01498-x","DOI":"10.1007\/s12311-022-01498-x"},{"issue":"2","key":"2872_CR73","doi-asserted-by":"publisher","first-page":"1560","DOI":"10.1016\/j.neuroimage.2011.08.065","volume":"59","author":"CJ Stoodley","year":"2012","unstructured":"Stoodley CJ, Valera EM, Schmahmann JD (2012) Functional topography of the Cerebellum for Motor and Cognitive tasks: an fMRI study. NeuroImage 59(2):1560\u20131570. https:\/\/doi.org\/10.1016\/j.neuroimage.2011.08.065","journal-title":"NeuroImage"},{"key":"2872_CR74","doi-asserted-by":"publisher","unstructured":"Sultan F, Glickstein M (2007) The cerebellum: Comparative and animal studies. Cerebellum Sep 1;6(3):168\u201376. https:\/\/doi.org\/10.1080\/14734220701332486","DOI":"10.1080\/14734220701332486"},{"key":"2872_CR75","doi-asserted-by":"publisher","DOI":"10.1002\/ejp.4734","author":"VS Vasiliou","year":"2024","unstructured":"Vasiliou VS, Konstantinou N, Christou Y, Papacostas S, Constantinidou F, Heracleous E, Seimenis I, Karekla M (2024) Neural correlates of pain acceptance and the role of the cerebellum: functional connectivity and anatomical differences in individuals with headaches versus matched controls. Eur J Pain. https:\/\/doi.org\/10.1002\/ejp.4734","journal-title":"Eur J Pain"},{"key":"2872_CR76","doi-asserted-by":"publisher","unstructured":"Wang M, Duong TL, Rea BJ, Waite JS, Huebner MW, Flinn HC, Russo AF, Sowers LP (2022) CGRP Administration into the Cerebellum evokes light aversion, Tactile Hypersensitivity, and nociceptive squint in mice. Front Pain Res Vol 3. https:\/\/doi.org\/10.3389\/fpain.2022.861598","DOI":"10.3389\/fpain.2022.861598"},{"issue":"5944","key":"2872_CR77","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1038\/306686a0","volume":"15","author":"CJ Woolf","year":"1983","unstructured":"Woolf CJ (1983) Evidence for a central component of post-injury pain hypersensitivity. Nat Dec 15(5944):686\u2013688. https:\/\/doi.org\/10.1038\/306686a0","journal-title":"Nat Dec"},{"issue":"5472","key":"2872_CR78","doi-asserted-by":"publisher","first-page":"1765","DOI":"10.1126\/science.288.5472.1765","volume":"9","author":"CJ Woolf","year":"2000","unstructured":"Woolf CJ, Salter MW (2000) Neuronal plasticity: increasing the Gain in Pain. Sci Jun 9(5472):1765\u20131768. https:\/\/doi.org\/10.1126\/science.288.5472.1765","journal-title":"Sci Jun"},{"issue":"33","key":"2872_CR79","doi-asserted-by":"publisher","first-page":"10264","DOI":"10.1523\/JNEUROSCI.4648-08.2009","volume":"19","author":"MD Yelle","year":"2009","unstructured":"Yelle MD, Oshiro Y, Kraft RA, Coghill RC (2009) Temporal filtering of nociceptive information by dynamic activation of Endogenous Pain Modulatory systems. J Neurosci Aug 19(33):10264\u201310271. https:\/\/doi.org\/10.1523\/JNEUROSCI.4648-08.2009","journal-title":"J Neurosci Aug"}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-024-02872-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00702-024-02872-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-024-02872-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T15:14:32Z","timestamp":1741965272000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00702-024-02872-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,11]]},"references-count":77,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["2872"],"URL":"https:\/\/doi.org\/10.1007\/s00702-024-02872-1","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,11]]},"assertion":[{"value":"2 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 January 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}