{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T22:09:29Z","timestamp":1778278169453,"version":"3.51.4"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T00:00:00Z","timestamp":1753056000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T00:00:00Z","timestamp":1753056000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neural Transm"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s00702-025-02985-1","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T07:07:55Z","timestamp":1753081675000},"page":"65-74","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of blood pressure variability with white matter hyperintensities and nigrostriatal dopaminergic deficits in drug-na\u00efve Parkinson\u2019s disease"],"prefix":"10.1007","volume":"133","author":[{"given":"Hiromasa","family":"Matsuno","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4156-5617","authenticated-orcid":false,"given":"Tadashi","family":"Umehara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Mimori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masakazu","family":"Ozawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomotaka","family":"Shiraishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asako","family":"Onda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiko","family":"Bono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shusaku","family":"Omoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renpei","family":"Sengoku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidetomo","family":"Murakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Iguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,7,21]]},"reference":[{"key":"2985_CR1","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1136\/jnnp-2012-303135","volume":"84","author":"M Asahina","year":"2013","unstructured":"Asahina M, Vichayanrat E, Low DA et al (2013) Autonomic dysfunction in parkinsonian disorders: assessment and pathophysiology. J Neurol Neurosurg Psychiatry 84:674\u2013680. https:\/\/doi.org\/10.1136\/jnnp-2012-303135","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2985_CR2","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1016\/j.bbr.2009.12.048","volume":"221","author":"NI Bohnen","year":"2011","unstructured":"Bohnen NI, Albin RL (2011) The cholinergic system and Parkinson disease. Behav Brain Res 221:564\u2013573. https:\/\/doi.org\/10.1016\/j.bbr.2009.12.048","journal-title":"Behav Brain Res"},{"key":"2985_CR3","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/s00441-004-0956-9","volume":"318","author":"H Braak","year":"2004","unstructured":"Braak H, Ghebremedhin E, Rub U et al (2004) Stages in the development of Parkinson\u2019s disease-related pathology. Cell Tissue Res 318:121\u2013134. https:\/\/doi.org\/10.1007\/s00441-004-0956-9","journal-title":"Cell Tissue Res"},{"key":"2985_CR4","doi-asserted-by":"publisher","first-page":"21","DOI":"10.2967\/jnmt.118.222349","volume":"47","author":"JE Brogley","year":"2019","unstructured":"Brogley JE (2019) DaTQUANT: the future of diagnosing Parkinson disease. J Nucl Med Technol 47:21\u201326. https:\/\/doi.org\/10.2967\/jnmt.118.222349","journal-title":"J Nucl Med Technol"},{"key":"2985_CR5","doi-asserted-by":"publisher","DOI":"10.1111\/ene.16061","volume":"31","author":"I Cani","year":"2024","unstructured":"Cani I, Guaraldi P, Giannini G et al (2024) Levodopa-induced orthostatic hypotension in parkinsonism: a red flag of autonomic failure. Eur J Neurol 31:e16061. https:\/\/doi.org\/10.1111\/ene.16061","journal-title":"Eur J Neurol"},{"key":"2985_CR6","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/S1474-4422(06)70373-8","volume":"5","author":"KR Chaudhuri","year":"2006","unstructured":"Chaudhuri KR, Healy DG, Schapira AH (2006) Non-motor symptoms of Parkinson\u2019s disease: diagnosis and management. Lancet Neurol 5:235\u2013245. https:\/\/doi.org\/10.1016\/S1474-4422(06)70373-8","journal-title":"Lancet Neurol"},{"key":"2985_CR7","doi-asserted-by":"publisher","first-page":"23886","DOI":"10.1073\/pnas.2003963117","volume":"117","author":"Y Choi","year":"2020","unstructured":"Choi Y, Shin EY, Kim S (2020) Spatiotemporal dissociation of fMRI activity in the caudate nucleus underlies human de novo motor skill learning. Proc Natl Acad Sci USA 117:23886\u201323897. https:\/\/doi.org\/10.1073\/pnas.2003963117","journal-title":"Proc Natl Acad Sci USA"},{"key":"2985_CR8","doi-asserted-by":"crossref","unstructured":"Churchyard A, Mathias CJ, Lees AJ (1999) Selegiline-induced\u00a0postural\u00a0hypotension\u00a0in\u00a0Parkinson's\u00a0disease: a longitudinal study on the effects of drug withdrawal. Mov Disord 14:246\u201351. https:\/\/doi.org\/10.1002\/1531-8257(199903)14:2<246::aid-mds1008>3.0.co;2-p","DOI":"10.1002\/1531-8257(199903)14:2<246::AID-MDS1008>3.0.CO;2-P"},{"key":"2985_CR9","unstructured":"DaTQUANT, GE Healthcare Website. https:\/\/www.gehealthcare.com\/products\/molecular-imaging-agents\/datquant, Accessed March 4, 2025."},{"key":"2985_CR10","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.3233\/JPD-181474","volume":"8","author":"ER Dorsey","year":"2018","unstructured":"Dorsey ER, Sherer T, Okun MS, Bloem BR (2018) The emerging evidence of the Parkinson pandemic. J Parkinsons Dis 8:S3-8. https:\/\/doi.org\/10.3233\/JPD-181474","journal-title":"J Parkinsons Dis"},{"key":"2985_CR11","doi-asserted-by":"publisher","first-page":"1291","DOI":"10.1007\/s00415-014-7339-2","volume":"261","author":"A Fanciulli","year":"2014","unstructured":"Fanciulli A, Strano S, Ndayisaba JP et al (2014) Detecting nocturnal hypertension in Parkinson\u2019s disease and multiple system atrophy: proposal of a decision-support algorithm. J Neurol 261:1291\u20131299. https:\/\/doi.org\/10.1007\/s00415-014-7339-2","journal-title":"J Neurol"},{"key":"2985_CR12","doi-asserted-by":"publisher","first-page":"2414","DOI":"10.1177\/0271678X16667524","volume":"37","author":"C Fuente Mora","year":"2017","unstructured":"Fuente Mora C, Palma JA, Kaufmann H, Norcliffe-Kaufmann L (2017) Cerebral autoregulation and symptoms of orthostatic hypotension in familial dysautonomia. J Cereb Blood Flow Metab 37:2414\u20132422. https:\/\/doi.org\/10.1177\/0271678X16667524","journal-title":"J Cereb Blood Flow Metab"},{"key":"2985_CR13","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/S1474-4422(18)30295-3","volume":"17","author":"GBD","year":"2016","unstructured":"GBD (2016) Parkinson\u2019s Disease Collaborators (2018) Global, regional, and national burden of Parkinson\u2019s disease, 1990\u20132016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol 17:939\u2013953. https:\/\/doi.org\/10.1016\/S1474-4422(18)30295-3","journal-title":"Lancet Neurol"},{"key":"2985_CR14","doi-asserted-by":"publisher","first-page":"655","DOI":"10.1016\/s0149-7634(00)00028-2","volume":"24","author":"M Gesi","year":"2000","unstructured":"Gesi M, Soldani P, Giorgi FS et al (2000) The role of the locus coeruleus in the development of Parkinson\u2019s disease. Neurosci Biobehav Rev 24:655\u2013668. https:\/\/doi.org\/10.1016\/s0149-7634(00)00028-2","journal-title":"Neurosci Biobehav Rev"},{"key":"2985_CR15","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1212\/WNL.0000000000002086","volume":"85","author":"DS Goldstein","year":"2015","unstructured":"Goldstein DS, Holmes C, Sharabi Y et al (2015) Survival in synucleinopathies: a prospective cohort study. Neurology 85:1554\u20131561. https:\/\/doi.org\/10.1212\/WNL.0000000000002086","journal-title":"Neurology"},{"key":"2985_CR16","doi-asserted-by":"publisher","first-page":"523","DOI":"10.1111\/j.1468-1331.2007.01727.x","volume":"14","author":"M Guttman","year":"2007","unstructured":"Guttman M, Boileau I, Warsh J et al (2007) Brain serotonin transporter binding in non-depressed patients with Parkinson\u2019s disease. Eur J Neurol 14:523\u2013528. https:\/\/doi.org\/10.1111\/j.1468-1331.2007.01727.x","journal-title":"Eur J Neurol"},{"key":"2985_CR17","doi-asserted-by":"publisher","first-page":"1581","DOI":"10.1016\/j.ultrasmedbio.2010.06.016","volume":"36","author":"C Haubrich","year":"2010","unstructured":"Haubrich C, Pies K, Dafotakis M, Block F, Kloetzsch C, Diehl RR (2010) Transcranial doppler monitoring in Parkinson\u2019s disease: cerebrovascular compensation of orthostatic hypotension. Ultrasound Med Biol 36:1581\u20131587. https:\/\/doi.org\/10.1016\/j.ultrasmedbio.2010.06.016","journal-title":"Ultrasound Med Biol"},{"key":"2985_CR18","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1002\/ana.1006","volume":"49","author":"MJ Hilz","year":"2001","unstructured":"Hilz MJ, D\u00fctsch M, Perrine K, Nelson PK, Rauhut U, Devinsky O (2001) Hemispheric influence on autonomic modulation and baroreflex sensitivity. Ann Neurol 49:575\u2013584. https:\/\/doi.org\/10.1002\/ana.1006","journal-title":"Ann Neurol"},{"key":"2985_CR19","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","volume":"55","author":"AJ Hughes","year":"1992","unstructured":"Hughes AJ, Daniel SE, Kilford L, Lees AJ (1992) Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease. A clinico-pathological study of 100 cases. J Neurol Neurosurgery Psychiatry 55:181\u2013184. https:\/\/doi.org\/10.1136\/jnnp.55.3.181","journal-title":"J Neurol Neurosurgery Psychiatry"},{"key":"2985_CR20","doi-asserted-by":"publisher","first-page":"1289","DOI":"10.1161\/HYPERTENSIONAHA.120.14678","volume":"75","author":"LM Jenkins","year":"2020","unstructured":"Jenkins LM, Garner CR, Kurian S et al (2020) Cumulative blood pressure exposure, basal ganglia, and thalamic morphology in midlife. Hypertension 75:1289\u20131295. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.120.14678","journal-title":"Hypertension"},{"key":"2985_CR21","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1002\/mds.28510","volume":"36","author":"SH Jeong","year":"2021","unstructured":"Jeong SH, Lee HS, Jung JH et al (2021) White matter hyperintensities, dopamine loss, and motor deficits in de novo Parkinson\u2019s disease. Mov Disord 36:1411\u20131419. https:\/\/doi.org\/10.1002\/mds.28510","journal-title":"Mov Disord"},{"key":"2985_CR22","doi-asserted-by":"publisher","first-page":"1149615","DOI":"10.3389\/fneur.2023.1149615","volume":"14","author":"A Kakimoto","year":"2023","unstructured":"Kakimoto A, Kawazoe M, Kurihara K et al (2023) Impact of non-motor fluctuations on QOL in patients with Parkinson\u2019s disease. Front Neurol 14:1149615. https:\/\/doi.org\/10.3389\/fneur.2023.1149615","journal-title":"Front Neurol"},{"key":"2985_CR23","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1212\/WNL.0b013e31826c1acd","volume":"79","author":"JS Kim","year":"2012","unstructured":"Kim JS, Oh YS, Lee KS, Kim YI, Yang DW, Goldstein DS (2012) Association of cognitive dysfunction with neurocirculatory abnormalities in early Parkinson disease. Neurology 79:1323\u20131331. https:\/\/doi.org\/10.1212\/WNL.0b013e31826c1acd","journal-title":"Neurology"},{"key":"2985_CR24","doi-asserted-by":"publisher","first-page":"1835","DOI":"10.1007\/s00702-021-02418-9","volume":"128","author":"T Kitagawa","year":"2021","unstructured":"Kitagawa T, Umehara T, Oka H et al (2021) Association between heart rate variability and striatal dopamine depletion in Parkinson\u2019s disease. J Neural Transm (Vienna) 128:1835\u20131840. https:\/\/doi.org\/10.1007\/s00702-021-02418-9","journal-title":"J Neural Transm (Vienna)"},{"key":"2985_CR25","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1001\/archneur.57.10.1461","volume":"57","author":"K Kujawa","year":"2000","unstructured":"Kujawa K, Leurgans S, Raman R, Blasucci L, Goetz CG (2000) Acute orthostatic hypotension when starting dopamine agonists in Parkinson\u2019s disease. Arch Neurol 57:1461\u20131463. https:\/\/doi.org\/10.1001\/archneur.57.10.1461","journal-title":"Arch Neurol"},{"key":"2985_CR26","doi-asserted-by":"publisher","first-page":"546","DOI":"10.1111\/jch.13521","volume":"21","author":"N Magkas","year":"2019","unstructured":"Magkas N, Tsioufis C, Thomopoulos C et al (2019) Orthostatic hypotension: from pathophysiology to clinical applications and therapeutic considerations. J Clin Hypertens (Greenwich) 21:546\u2013554. https:\/\/doi.org\/10.1111\/jch.13521","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"2985_CR27","doi-asserted-by":"publisher","first-page":"2244","DOI":"10.1097\/HJH.0b013e328330a94f","volume":"27","author":"E Manios","year":"2009","unstructured":"Manios E, Tsagalis G, Tsivgoulis G et al (2009) Time rate of blood pressure variation is associated with impaired renal function in hypertensive patients. J Hypertens 27:2244\u20132248. https:\/\/doi.org\/10.1097\/HJH.0b013e328330a94f","journal-title":"J Hypertens"},{"key":"2985_CR28","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1002\/mds.23462","volume":"26","author":"P Martinez-Martin","year":"2011","unstructured":"Martinez-Martin P, Rodriguez-Blazquez C, Kurtis MM, Chaudhuri KR, NMSS Validation Group (2011) The impact of non-motor symptoms on health-related quality of life of patients with Parkinson\u2019s disease. Mov Disord 26:399\u2013406. https:\/\/doi.org\/10.1002\/mds.23462","journal-title":"Mov Disord"},{"key":"2985_CR29","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1002\/mds.26632","volume":"31","author":"C McDonald","year":"2016","unstructured":"McDonald C, Newton JL, Burn DJ (2016) Orthostatic hypotension and cognitive impairment in Parkinson\u2019s disease: causation or association? Mov Disord 31:937\u2013946. https:\/\/doi.org\/10.1002\/mds.26632","journal-title":"Mov Disord"},{"key":"2985_CR30","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1097\/HJH.0b013e328363e964","volume":"31","author":"E O\u2019Brien","year":"2013","unstructured":"O\u2019Brien E, Parati G, Stergiou G et al (2013) European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens 31:1731\u20131768. https:\/\/doi.org\/10.1097\/HJH.0b013e328363e964","journal-title":"J Hypertens"},{"key":"2985_CR31","doi-asserted-by":"publisher","first-page":"23","DOI":"10.14802\/jmd.13006","volume":"6","author":"YS Oh","year":"2013","unstructured":"Oh YS, Kim JS, Lee KS (2013) Orthostatic and supine blood pressures are associated with white matter hyperintensities in Parkinson disease. J Movement Disorders 6:23\u201327. https:\/\/doi.org\/10.14802\/jmd.13006","journal-title":"J Movement Disorders"},{"key":"2985_CR32","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1186\/s12883-020-01928-5","volume":"20","author":"H Oka","year":"2020","unstructured":"Oka H, Umehara T, Nakahara A et al (2020) Comparisons of cardiovascular dysautonomia and cognitive impairment between de novo Parkinson\u2019s disease and de novo dementia with Lewy bodies. BMC Neurol 20:350. https:\/\/doi.org\/10.1186\/s12883-020-01928-5","journal-title":"BMC Neurol"},{"key":"2985_CR33","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1212\/WNL.0000000000000605","volume":"83","author":"JA Palma","year":"2014","unstructured":"Palma JA, Benarroch EE (2014) Neural control of the heart: recent concepts and clinical correlations. Neurology 83:261\u2013271. https:\/\/doi.org\/10.1212\/WNL.0000000000000605","journal-title":"Neurology"},{"key":"2985_CR34","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1097\/HJH.0000000000003363","volume":"41","author":"G Parati","year":"2023","unstructured":"Parati G, Bilo G, Kollias A et al (2023) Blood pressure variability: methodological aspects, clinical relevance and practical indications for management\u2014a European Society of Hypertension position paper. J Hypertens 41:527\u2013544. https:\/\/doi.org\/10.1097\/HJH.0000000000003363","journal-title":"J Hypertens"},{"key":"2985_CR35","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1136\/jnnp-2018-320157","volume":"90","author":"J Pasquini","year":"2019","unstructured":"Pasquini J, Durcan R, Wiblin L et al (2019) Clinical implications of early caudate dysfunction in Parkinson\u2019s disease. J Neurol Neurosurg Psychiatry 90:1098\u20131104. https:\/\/doi.org\/10.1136\/jnnp-2018-320157","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2985_CR36","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1016\/0028-3908(83)90095-3","volume":"22","author":"JH Pazo","year":"1983","unstructured":"Pazo JH, Medina JH (1983) Cholinergic mechanisms within the caudate nucleus mediate changes in blood pressure. Neuropharmacology 22:717\u2013720. https:\/\/doi.org\/10.1016\/0028-3908(83)90095-3","journal-title":"Neuropharmacology"},{"key":"2985_CR37","doi-asserted-by":"publisher","first-page":"S119","DOI":"10.1016\/j.parkreldis.2015.09.004","volume":"22","author":"RF Pfeiffer","year":"2016","unstructured":"Pfeiffer RF (2016) Non-motor symptoms in Parkinson\u2019s disease. Parkinsonism Relat Disord 22:S119\u2013S122. https:\/\/doi.org\/10.1016\/j.parkreldis.2015.09.004","journal-title":"Parkinsonism Relat Disord"},{"key":"2985_CR38","doi-asserted-by":"publisher","first-page":"1257","DOI":"10.1136\/jnnp-2019-320846","volume":"90","author":"A Pilotto","year":"2019","unstructured":"Pilotto A, Romagnolo A, Tuazon JA et al (2019) Orthostatic hypotension and REM sleep behaviour disorder: impact on clinical outcomes in alpha-synucleinopathies. J Neurol Neurosurg Psychiatry 90:1257\u20131263. https:\/\/doi.org\/10.1136\/jnnp-2019-320846","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"2985_CR39","doi-asserted-by":"publisher","first-page":"e342","DOI":"10.1097\/RLU.0000000000003107","volume":"45","author":"HW Shin","year":"2020","unstructured":"Shin HW, Chung SJ, Lee S et al (2020) Dysautonomia is linked to striatal dopamine deficits and regional cerebral perfusion in early Parkinson disease. Clin Nucl Med 45:e342\u2013e348. https:\/\/doi.org\/10.1097\/RLU.0000000000003107","journal-title":"Clin Nucl Med"},{"key":"2985_CR40","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1159\/000104478","volume":"24","author":"Y Shinohara","year":"2007","unstructured":"Shinohara Y, Tohgi H, Hirai S et al (2007) Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA study). 1. Design and results at enrollment. Cerebrovasc Dis 24:202\u2013209. https:\/\/doi.org\/10.1159\/000104478","journal-title":"Cerebrovasc Dis"},{"key":"2985_CR41","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.parkreldis.2014.02.007","volume":"20","author":"T Umehara","year":"2014","unstructured":"Umehara T, Toyoda C, Oka H (2014) Postprandial hypotension in de novo Parkinson\u2019s disease: a comparison with orthostatic hypotension. Parkinsonism Relat Disord 20:573\u2013577. https:\/\/doi.org\/10.1016\/j.parkreldis.2014.02.007","journal-title":"Parkinsonism Relat Disord"},{"key":"2985_CR42","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s10286-015-0324-8","volume":"26","author":"T Umehara","year":"2016","unstructured":"Umehara T, Matsuno H, Toyoda C et al (2016a) Clinical characteristics of supine hypertension in de novo Parkinson disease. Clin Auton Res 26:15\u201321. https:\/\/doi.org\/10.1007\/s10286-015-0324-8","journal-title":"Clin Auton Res"},{"key":"2985_CR43","doi-asserted-by":"publisher","first-page":"1331","DOI":"10.1007\/s00702-016-1594-6","volume":"123","author":"T Umehara","year":"2016","unstructured":"Umehara T, Nakahara A, Matsuno H, Toyoda C, Oka H (2016b) Predictors of postprandial hypotension in elderly patients with de novo Parkinson\u2019s disease. J Neural Transm 123:1331\u20131339. https:\/\/doi.org\/10.1007\/s00702-016-1594-6","journal-title":"J Neural Transm"},{"key":"2985_CR44","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1038\/sj.jhh.1000808","volume":"13","author":"MS van der Steen","year":"1999","unstructured":"van der Steen MS, Lenders JW, Graafsma SJ et al (1999) Reproducibility of ambulatory blood pressure monitoring in daily practice. J Hum Hypertens 13:303\u2013308. https:\/\/doi.org\/10.1038\/sj.jhh.1000808","journal-title":"J Hum Hypertens"},{"key":"2985_CR45","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1007\/s00415-020-09785-5","volume":"267","author":"DN van Deursen","year":"2020","unstructured":"van Deursen DN, van den Heuvel OA, Booij J, Berendse HW, Vriend C (2020) Autonomic failure in Parkinson\u2019s disease is associated with striatal dopamine deficiencies. J Neurol 267:1922\u20131930. https:\/\/doi.org\/10.1007\/s00415-020-09785-5","journal-title":"J Neurol"},{"key":"2985_CR46","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.neuroimage.2005.05.026","volume":"27","author":"NJ van Osch","year":"2005","unstructured":"van Osch NJ, Jansen PA, Vingerhoets PW, van der Grond J (2005) Association between supine cerebral perfusion and symptomatic orthostatic hypotension. Neuroimage 27:789\u2013794. https:\/\/doi.org\/10.1016\/j.neuroimage.2005.05.026","journal-title":"Neuroimage"},{"key":"2985_CR47","doi-asserted-by":"publisher","first-page":"1046","DOI":"10.1093\/ajh\/hpw037","volume":"29","author":"P Veloudi","year":"2016","unstructured":"Veloudi P, Blizzard CL, Head GA, Abhayaratna WP, Stowasser M, Sharma JE (2016) Blood pressure variability and prediction of target organ damage in patients with uncomplicated hypertension. Am J Hypertens 29:1046\u20131054. https:\/\/doi.org\/10.1093\/ajh\/hpw037","journal-title":"Am J Hypertens"},{"key":"2985_CR48","doi-asserted-by":"publisher","first-page":"2043","DOI":"10.1097\/HJH.0000000000002505","volume":"38","author":"SW Yoo","year":"2020","unstructured":"Yoo SW, Yun E, Bang M et al (2020) Blood pressure lability is associated with subcortical atrophy in early Parkinson\u2019s disease. J Hypertens 38:2043\u20132049. https:\/\/doi.org\/10.1097\/HJH.0000000000002505","journal-title":"J Hypertens"},{"key":"2985_CR49","doi-asserted-by":"publisher","first-page":"22161","DOI":"10.1038\/s41598-022-26811-w","volume":"12","author":"SW Yoo","year":"2022","unstructured":"Yoo SW, Ha S, Oh YS et al (2022) Caudate-anchored cognitive connectivity pursuant to orthostatic hypotension in early Parkinson\u2019s disease. Sci Rep 12:22161. https:\/\/doi.org\/10.1038\/s41598-022-26811-w","journal-title":"Sci Rep"}],"container-title":["Journal of Neural Transmission"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-025-02985-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00702-025-02985-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00702-025-02985-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T14:34:14Z","timestamp":1769092454000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00702-025-02985-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,21]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["2985"],"URL":"https:\/\/doi.org\/10.1007\/s00702-025-02985-1","relation":{},"ISSN":["0300-9564","1435-1463"],"issn-type":[{"value":"0300-9564","type":"print"},{"value":"1435-1463","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,21]]},"assertion":[{"value":"3 April 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 July 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}