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Lifestyle consultation plays an essential and constantly growing role in clinical settings. In this review, we highlight the usability of lifestyle medicine as a framework for both well-established and novel roles of environmental triggers and non-pharmacological prevention and treatment in Parkinson\u2019s Disease (PD). We summarize the current understanding of the modulation of PD risk and progression by lifestyle-related domains and provide a review of recent insights from approaches targeting physical activity and stress management as well as dietary interventions, including general dietary patterns, individual food groups, supplements, and microbiota-directed strategies in the context of PD. 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