{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T22:50:33Z","timestamp":1790895033857,"version":"4.1.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,9,25]],"date-time":"2011-09-25T00:00:00Z","timestamp":1316908800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2011,9,25]],"date-time":"2011-09-25T00:00:00Z","timestamp":1316908800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Virol"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1007\/s00705-011-1115-8","type":"journal-article","created":{"date-parts":[[2011,9,24]],"date-time":"2011-09-24T04:48:01Z","timestamp":1316839681000},"page":"121-127","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin"],"prefix":"10.1007","volume":"157","author":[{"given":"Andrey A.","family":"Kolokoltsov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shramika","family":"Adhikary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Garver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lela","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Davey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric M.","family":"Vela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2011,9,25]]},"reference":[{"key":"1115_CR1","doi-asserted-by":"publisher","first-page":"S205","DOI":"10.1086\/520601","volume":"196","author":"J Towner","year":"2007","unstructured":"Towner J, Sealy T, Ksiazek TG, Nichol ST (2007) High-throughput molecular detection of hemorrhagic fever virus threats with applications for outbreak settings. J Infect Dis 196:S205\u2013S212","journal-title":"J Infect Dis"},{"key":"1115_CR2","doi-asserted-by":"publisher","first-page":"e1000904","DOI":"10.1371\/journal.ppat.1000904","volume":"6","author":"LE Hensley","year":"2010","unstructured":"Hensley LE, Mulangu S, Asiedu C, Johnson J, Honko AN, Stanley D, Fabozzi G, Nichol ST, Ksiazek TG, Rollin PE, Wahl-Jensen V, Bailey M, Jahrling PB, Roederer M, Koup RA, Sullivan NJ (2010) Demonstration of cross-protective vaccine immunity against an emerging pathogenic Ebolavirus species. PLoS Pathog 6:e1000904","journal-title":"PLoS Pathog"},{"key":"1115_CR3","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1056\/NEJM198601023140104","volume":"314","author":"JB McCormick","year":"1986","unstructured":"McCormick JB, King I, Webb P, Johnson K, O\u2019Sullivan R, Smith E, Tripple S, Tong T (1986) Lassa fever: effective therapy with Ribavirin. N Engl J Med 314:20\u201326","journal-title":"N Engl J Med"},{"key":"1115_CR4","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.2460\/ajvr.2002.63.1124","volume":"63","author":"S Akula","year":"2002","unstructured":"Akula S, Hurley D, Wixon R, Wang C, Chase C (2002) Effect of genistein on replication of bovine herpes virus type 1. Am J Veter Res 63:1124\u20131128","journal-title":"Am J Veter Res"},{"issue":"9","key":"1115_CR5","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1093\/jn\/137.9.2068","volume":"137","author":"A Andres","year":"2007","unstructured":"Andres A, Donovan SM, Kuhlenschmidt TB, Kuhlenschmidt MS (2007) Isoflavones at concentrations present in soy infant formula inhibit Rotavirus infection in vitro. J Nutr 137(9):2068\u20132073","journal-title":"J Nutr"},{"key":"1115_CR6","doi-asserted-by":"publisher","first-page":"10826","DOI":"10.1128\/JVI.79.16.10826-10829.2005","volume":"79","author":"S Lecot","year":"2005","unstructured":"Lecot S, Belouzard S, Dubuisson J, Rouille Y (2005) Bovine viral diarrhea virus entry is dependent on clathrin-mediated endocytosis. J Virol 79:10826\u201310829","journal-title":"J Virol"},{"key":"1115_CR7","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1007\/BF01309554","volume":"132","author":"Y Yura","year":"1993","unstructured":"Yura Y, Yoshida H, Sato M (1993) Inhibition of herpes simplex virus replication by genistein, an inhibitor of protein-tyrosine kinase. Arch Virol 132:451\u2013461","journal-title":"Arch Virol"},{"key":"1115_CR8","doi-asserted-by":"publisher","first-page":"1391","DOI":"10.1007\/s00705-008-0129-3","volume":"153","author":"EM Vela","year":"2008","unstructured":"Vela EM, Colpitts T, Zhang L, Davey R, Aronson J (2008) Pichind\u00e9 virus is trafficked through a dynamin 2 endocytic pathway that is dependent on cellular Rab5- and Rab7-mediated endosomes. Arch Virol 153:1391\u20131396","journal-title":"Arch Virol"},{"key":"1115_CR9","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1016\/j.antiviral.2010.06.007","volume":"87","author":"EM Vela","year":"2010","unstructured":"Vela EM, Knostman KA, Mott JM, Warren RL, Garver JN, Vela LJ, Stammen RL (2010) Genistein, a general kinase inhibitor, as a potential antiviral for arenaviral hemorrhagic fever as described in the Pirital virus-Syrian golden hamster model. Antivir Res 87:318\u2013328","journal-title":"Antivir Res"},{"key":"1115_CR10","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.4269\/ajtmh.2006.74.1096","volume":"74","author":"E Sbrana","year":"2006","unstructured":"Sbrana E, Mateo RI, Xiao S-Y, Popov VL, Newman PC, Tesh RB (2006) Clinical laboratory, virologic, and pathologic changes in hamsters experimentally infected with Pirital virus (Arenaviridae): a rodent model of Lassa fever. Am J Trop Med Hyg 74:1096\u20131102","journal-title":"Am J Trop Med Hyg"},{"key":"1115_CR11","first-page":"15","volume":"2","author":"E Vela","year":"2010","unstructured":"Vela E, Knostman K, Warren R, Garver J, Stammen R (2010) The disease progression associated with Pirital virus infection in the Syrian golden hamster. J Infect Dis Immun 2:15\u201323","journal-title":"J Infect Dis Immun"},{"key":"1115_CR12","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4269\/ajtmh.2001.64.111","volume":"64","author":"S-Y Xiao","year":"2001","unstructured":"Xiao S-Y, Zhang H, Yang Y, Tesh RB (2001) Pirital virus (Arenaviridae) infection in the Syrian golden hamster, Mesocricetus auratus: a new animal model for arenaviral hemorrhagic fever. Am J Trop Med Hyg 64:111\u2013118","journal-title":"Am J Trop Med Hyg"},{"key":"1115_CR13","first-page":"3859","volume":"56","author":"Y Han","year":"1996","unstructured":"Han Y, Caday CG, Nanda A, Cavenee WK, Huang H-JS (1996) Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors. Cancer Res 56:3859\u20133861","journal-title":"Cancer Res"},{"key":"1115_CR14","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.antiviral.2007.09.005","volume":"77","author":"EM Vela","year":"2008","unstructured":"Vela EM, Bowick GC, Herzog NK, Aronson JF (2008) Genistein treatment of cells inhibits arenavirus infection. Antivir Res 77:153\u2013156","journal-title":"Antivir Res"},{"key":"1115_CR15","doi-asserted-by":"crossref","first-page":"8476","DOI":"10.1128\/JVI.73.10.8476-8484.1999","volume":"73","author":"JM Smit","year":"1999","unstructured":"Smit JM, Bittman R, Wilschut J (1999) Low-pH-dependent fusion of Sindbis virus with receptor-free cholesterol- and sphingolipid-containing liposomes. J Virol 73:8476\u20138484","journal-title":"J Virol"},{"key":"1115_CR16","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1093\/nar\/29.9.e45","volume":"29","author":"MW Pfaffl","year":"2001","unstructured":"Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:2002\u20132007","journal-title":"Nucleic Acids Res"},{"key":"1115_CR17","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.1128\/JVI.02199-06","volume":"81","author":"G Bowick","year":"2007","unstructured":"Bowick G, Fennewald S, Scott E, Zhang L, Elsom B, Aronson J, Spratt H, Luxon B, Gorenstein D, Herzog N (2007) Identification of differentially activated cell-signalling networks associated with Pichinde virus pathogenesis by using systems kinomics. J Virol 81:1923\u20131933","journal-title":"J Virol"},{"key":"1115_CR18","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/nature05539","volume":"446","author":"S Radoshitzky","year":"2007","unstructured":"Radoshitzky S, Abraham J, Spiropoulou C, Kuhn J, Nguyen D, Wenhui L, Nagel J, Schmidt P, Nunberg J, Andrews N, Farzan M, Choe H (2007) Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses. Nature 446:92\u201396","journal-title":"Nature"},{"key":"1115_CR19","doi-asserted-by":"publisher","first-page":"1776","DOI":"10.1099\/vir.0.82808-0","volume":"88","author":"M Martinez","year":"2007","unstructured":"Martinez M, Cordo S, Candurra N (2007) Characterization of Junin arenavirus cell entry. J Gen Virol 88:1776\u20131784","journal-title":"J Gen Virol"},{"key":"1115_CR20","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.virol.2007.07.014","volume":"369","author":"E Vela","year":"2007","unstructured":"Vela E, Zhang L, Colpitts T, Davey R, Aronson J (2007) Arenavirus entry occurs through a cholesterol-dependent, non-caveolar, clathrin-mediated endocytic mechanism. Virology 369:1\u201311","journal-title":"Virology"},{"key":"1115_CR21","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1007\/BF01718832","volume":"141","author":"V Castilla","year":"1996","unstructured":"Castilla V, Merisch S (1996) Low pH-induced fusion of Vero cells infected with Junin virus. Arch Virol 141:1307\u20131317","journal-title":"Arch Virol"},{"key":"1115_CR22","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1006\/viro.1994.1057","volume":"198","author":"C Di Simone","year":"1994","unstructured":"Di Simone C, Zandonatti M, Buchmeier M (1994) Acidic pH triggers LCMV membrane fusion activity and conformational change in the glycoprotein spike. Virology 198:455\u2013465","journal-title":"Virology"},{"key":"1115_CR23","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1006\/viro.1995.1225","volume":"209","author":"C Di Simone","year":"1995","unstructured":"Di Simone C, Buchmeier M (1995) Kinetics and pH dependence of acid-induced structural changes in the lymphoytic choriomeningitis virus glycoprotein complex. Virology 209:3\u20139","journal-title":"Virology"},{"key":"1115_CR24","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1242\/jcs.112.9.1303","volume":"112","author":"A Benmerah","year":"1999","unstructured":"Benmerah A, Bayrou M, Cerf-Bensussan N, Dautry-Varsat A (1999) Inhibition of clathrin-coated pit assembly by an Eps15 mutant. J Cell Sci 112:1303\u20131311","journal-title":"J Cell Sci"},{"key":"1115_CR25","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1038\/nature01451","volume":"422","author":"S Conner","year":"2003","unstructured":"Conner S, Schmid S (2003) Regulated portasl of entry into the cell. Nature 422:37\u201344","journal-title":"Nature"},{"key":"1115_CR26","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S0968-0004(99)01538-8","volume":"25","author":"M McNiven","year":"2000","unstructured":"McNiven M, Cao H, Pitts K, Yoon Y (2000) The dynamin family of mechanoenzymes: pinching in new places. TRENDS Biochem Sci 25:115\u2013120","journal-title":"TRENDS Biochem Sci"},{"key":"1115_CR27","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/1743-422X-7-24","volume":"7","author":"F Ang","year":"2010","unstructured":"Ang F, Wong A, Ng M, Chu J (2010) Small interference RNA profiling reveals the essential role of human membrane trafficking genes in mediating the infectious entry of dengue virus. Virol J 7:24","journal-title":"Virol J"},{"key":"1115_CR28","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.virol.2010.02.015","volume":"401","author":"S Bhattacharyya","year":"2010","unstructured":"Bhattacharyya S, Warfield KL, Ruthel G, Bavari S, Aman MJ, Hope TJ (2010) Ebola virus uses clathrin-mediated endocytosis as an entry pathway. Virology 401:18\u201328","journal-title":"Virology"},{"key":"1115_CR29","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1006\/viro.2001.1303","volume":"294","author":"M Jin","year":"2002","unstructured":"Jin M, Park J, Lee S, Park B, Shin J, Song KJ, Ahn TI, Hwang SY, Ahn BY, Ahn K (2002) Hantaan virus enters cells by clathrin-dependent receptor-mediated endocytosis. Virology 294:60\u201369","journal-title":"Virology"},{"key":"1115_CR30","doi-asserted-by":"publisher","first-page":"13433","DOI":"10.1128\/JVI.77.24.13433-13438.2003","volume":"77","author":"G Simmons","year":"2003","unstructured":"Simmons G, Rennekamp AJ, Chai N, Vandenberghe LH, Riley JL, Bates P (2003) Folate receptor alpha and Caveolae are not required for Ebola virus glycoprotein-mediated viral infection. J Virol 77:13433\u201313438","journal-title":"J Virol"}],"container-title":["Archives of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-011-1115-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00705-011-1115-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-011-1115-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-011-1115-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T16:23:25Z","timestamp":1659111805000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00705-011-1115-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,25]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["1115"],"URL":"https:\/\/doi.org\/10.1007\/s00705-011-1115-8","relation":{},"ISSN":["0304-8608","1432-8798"],"issn-type":[{"value":"0304-8608","type":"print"},{"value":"1432-8798","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,25]]},"assertion":[{"value":"19 May 2011","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 September 2011","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2011","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}