{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:59:13Z","timestamp":1790643553505,"version":"4.1.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T00:00:00Z","timestamp":1552953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T00:00:00Z","timestamp":1552953600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Virol"],"published-print":{"date-parts":[[2019,5,1]]},"DOI":"10.1007\/s00705-019-04201-4","type":"journal-article","created":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T09:03:04Z","timestamp":1552986184000},"page":"1371-1382","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["TLR-5 agonist Salmonella abortus equi flagellin FliC enhances FliC-gD-based DNA vaccination against equine herpesvirus 1 infection"],"prefix":"10.1007","volume":"164","author":[{"given":"Yanan","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxin","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baojiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panpan","family":"Tong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caidie","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duoliang","family":"Ran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,3,19]]},"reference":[{"key":"4201_CR1","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/S0065-3527(08)60060-3","volume":"45","author":"BS Crabb","year":"1995","unstructured":"Crabb BS, Studdert MJ (1995) Equine herpesviruses 4 (equine rhinopneumonitis virus) and 1 (equine abortion virus). Adv Virus Res 45:153\u2013190","journal-title":"Adv Virus Res"},{"key":"4201_CR2","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1016\/j.cveq.2004.09.001","volume":"20","author":"SM Reed","year":"2004","unstructured":"Reed SM, Toribo RE (2004) Equine herpesvirus 1 and 4. Vet Clin Am Equine Pract 20:631\u2013642","journal-title":"Vet Clin Am Equine Pract"},{"key":"4201_CR3","doi-asserted-by":"publisher","first-page":"105","DOI":"10.2746\/042516408X253127","volume":"40","author":"GP Allen","year":"2008","unstructured":"Allen GP, Bolin DC, Bryant U, Carter CN, Giles RC, Harrison LR, Hong CB, Jackson CB, Poonacha K, Wharton R, Williams NM (2008) Prevalence of latent, neuropathogenic equine herpesvirus-1 in the thoroughbred broodmare population of central kentucky. Equine Vet J 40:105\u2013110","journal-title":"Equine Vet J"},{"key":"4201_CR4","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1038\/icb.1996.84","volume":"74","author":"NJ Davis-Poynter","year":"1996","unstructured":"Davis-Poynter NJ, Farrell HE (1996) Masters of deception:a review of herpesvirus immune evasion strategies. Immunol Cell Biol 74:513\u2013522","journal-title":"Immunol Cell Biol"},{"key":"4201_CR5","first-page":"128","volume":"15","author":"JR Gilkerson","year":"1997","unstructured":"Gilkerson JR, Love DN, Whalley JM (1997) Serological evidence of equineherpesvirus 1 (EHV-1) infection in thoroughbred foals 30\u2013120\u00a0days of age. Aust Vet J 15:128\u2013134","journal-title":"Aust Vet J"},{"key":"4201_CR6","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.tvjl.2004.04.018","volume":"170","author":"JR Patel","year":"2005","unstructured":"Patel JR, Heldens J (2005) Equine herpesviruses 1 (EHV-1) and 4 (EHV-4)-epidemiology, disease and immunoprophylaxis: a brief review. Vet J 170:14\u201323","journal-title":"Vet J"},{"key":"4201_CR7","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1080\/01652176.2000.9695030","volume":"22","author":"MC Van","year":"2000","unstructured":"Van MC, Willink DL, Smeenk LA, Brinkhof J, Terpstra C (2000) An equine herpesvirus 1 (EHV1) abortion storm at a riding school. Vet Q 22:83\u201387","journal-title":"Vet Q"},{"key":"4201_CR8","doi-asserted-by":"publisher","first-page":"2371","DOI":"10.1007\/s007050070027","volume":"145","author":"H Csellner","year":"2000","unstructured":"Csellner H, Walker C, Wellington JE, Mclure LE, Love DN, Whalley JM (2000) EHV-1 glycoprotein D (EHV-1 gD) is required for virus entry and cell-cell fusion, and an EHV-1 gD deletion mutant induces a protective immune response in mice. Arch Virol 145:2371\u20132385","journal-title":"Arch Virol"},{"key":"4201_CR9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.vetimm.2004.12.012","volume":"105","author":"CE Foote","year":"2005","unstructured":"Foote CE, Love DN, Gilkerson JR, Rota J, Trevor-Jones P, Ruitenberg KM, Wellington JE, Whalley JM (2005) Serum antibody responses to equine herpesvirus 1 glycoprotein d in horses, pregnant mares and young foals. Vet Immunol Immunopathol 105:47\u201357","journal-title":"Vet Immunol Immunopathol"},{"key":"4201_CR10","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1016\/j.vetimm.2006.01.009","volume":"111","author":"CU Weerasinghe","year":"2006","unstructured":"Weerasinghe CU, Learmonth GS, Gilkerson JR, Foote CE, Wellington JE, Whalley JM (2006) Equine herpesvirus 1 glycoprotein d expressed in E. coli provides partial protection against equine herpesvirus infection in mice and elicits virus-neutralizing antibodies in the horse. Vet Immunol Immunopathol 111:59\u201366","journal-title":"Vet Immunol Immunopathol"},{"key":"4201_CR11","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1016\/S0264-410X(98)00192-3","volume":"17","author":"KM Ruitenberg","year":"1999","unstructured":"Ruitenberg KM, Walker C, Wellington JE, Love DN, Whalley JM (1999) Dna-mediated immunization with glycoprotein d of equine herpesvirus 1 (EHV-1) in a murine model of EHV-1 respiratory infection. Vaccine 17:237\u2013244","journal-title":"Vaccine"},{"key":"4201_CR12","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/S0378-1135(00)00262-5","volume":"76","author":"C Walker","year":"2000","unstructured":"Walker C, Ruitenberg KM, Love DN, Whalley JM (2000) Immunization of BALB\/c mice with DNA encoding equine herpesvirus 1 (EHV-1) glycoprotein D affords partial protection in a model of EHV-1-induced abortion. Vet Microbiol 76:211\u2013220","journal-title":"Vet Microbiol"},{"key":"4201_CR13","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.vetimm.2006.01.008","volume":"111","author":"JM Minke","year":"2006","unstructured":"Minke JM, Fischer L, Baudu P, Guigal PM, Sindle T, Mumford JA, Audonnet JC (2006) Use of DNA and recombinant canarypox viral (ALVAC) vectors for equine herpes virus vaccination. Vet Immunol Immunopathol 111:47\u201357","journal-title":"Vet Immunol Immunopathol"},{"key":"4201_CR14","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.rvsc.2014.05.010","volume":"97","author":"D Xiong","year":"2014","unstructured":"Xiong D, Pan Z, Kang X, Wang J, Song L, Jiao X (2014) Molecular cloning and functional analysis of duck Toll-like receptor 5. Res Vet Sci 97:43\u201345","journal-title":"Res Vet Sci"},{"key":"4201_CR15","doi-asserted-by":"publisher","first-page":"5677","DOI":"10.4049\/jimmunol.1002156","volume":"185","author":"SB Mizel","year":"2010","unstructured":"Mizel SB, Bates JT (2010) Flagellin as an adjuvant: cellular mechanisms and potential. J Immunol 185:5677\u20135682","journal-title":"J Immunol"},{"key":"4201_CR16","doi-asserted-by":"publisher","first-page":"160","DOI":"10.1089\/vim.2013.0129","volume":"27","author":"PM St","year":"2014","unstructured":"St PM, Brisbin JT, Barjesteh N, Villaneueva AI, Parvizi P, Read LR, Nagy E, Sharif S (2014) Avian influenza virus vaccines containing toll-like receptors 2 and 5 ligand adjuvants promote protective immune responses in chickens. Viral Immunol 27:160\u2013166","journal-title":"Viral Immunol"},{"key":"4201_CR17","doi-asserted-by":"publisher","first-page":"388","DOI":"10.4049\/jimmunol.175.6.3882","volume":"175","author":"SE Applequist","year":"2005","unstructured":"Applequist SE, Rollman E, Wareing MD, Lid\u00e9n M, Rozell B, Hinkula J, Ljunggren HG (2005) Activation of innate immunity, inflammation, and potentiation of DNA vaccination through mammalian expression of the TLR5 agonist flagellin. J Immunol 175:388\u2013391","journal-title":"J Immunol"},{"key":"4201_CR18","doi-asserted-by":"publisher","first-page":"3341","DOI":"10.1016\/j.vaccine.2010.08.002","volume":"29","author":"F Steinhagen","year":"2011","unstructured":"Steinhagen F, Kinjo T, Bode C, Klinman DM (2011) Tlr-based immune adjuvants. Vaccine 29:3341\u20133355","journal-title":"Vaccine"},{"key":"4201_CR19","doi-asserted-by":"publisher","first-page":"e20928","DOI":"10.1371\/journal.pone.0020928","volume":"6","author":"G Liu","year":"2011","unstructured":"Liu G, Tarbet B, Song L, Reiserova L, Weaver B, Chen Y, Li H, Hou F, Liu X, Parent J, Umlauf S, Shaw A, Tussey L (2011) Immunogenicity and efficacy of flagellin-fused vaccine candidates targeting 2009 pandemic H1N1 influenza in mice. PLoS One 6:e20928","journal-title":"PLoS One"},{"key":"4201_CR20","doi-asserted-by":"publisher","first-page":"e2257","DOI":"10.1371\/journal.pone.0002257","volume":"3","author":"L Song","year":"2008","unstructured":"Song L, Nakaar V, Kavita U, Price A, Huleatt J, Tang J, Jacobs A, Liu G, Huang Y, Desai P, Maksymiuk G, Takahashi V, Umlauf S, Reiserova L, Bell R, Li H, Zhang Y, McDonald WF, Powell TJ, Tussey L (2008) Efficacious recombinant influenza vaccines produced by high yield bacterial expression: a solution to global pandemic and seasonal needs. PLoS One 3:e2257","journal-title":"PLoS One"},{"key":"4201_CR21","doi-asserted-by":"publisher","first-page":"5145","DOI":"10.1016\/j.vaccine.2011.05.041","volume":"29","author":"CB Turley","year":"2011","unstructured":"Turley CB, Rupp RE, Johnson C, Taylor DN, Wolfson J, Tussey L, Kavita U, Stanberry L, Shaw A (2011) Safety and immunogenicity of a recombinant M2e-flagellin influenza vaccine (STF2.4xM2e) in healthy adults. Vaccine 29:5145\u20135152","journal-title":"Vaccine"},{"key":"4201_CR22","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.1016\/j.vaccine.2012.12.059","volume":"31","author":"MR Asadi-Karam","year":"2013","unstructured":"Asadi-Karam MR, Oloomi M, Mahdavi M, Habibi M, Bouzari S (2013) Vaccination with recombinant fimH fused with flagellin enhances cellular and humoral immunity against urinary tract infection in mice. Vaccine 31:1210\u20131216","journal-title":"Vaccine"},{"key":"4201_CR23","doi-asserted-by":"publisher","first-page":"2499","DOI":"10.1016\/j.molimm.2008.01.005","volume":"45","author":"MV Le","year":"2008","unstructured":"Le MV, Robreau G, Mahana W (2008) Flagellin as a good carrier and potent adjuvant for Th1 response: study of mice immune response to the p27 (Rv2108) Mycobacterium tuberculosis antigen. Mol Immunol 45:2499\u20132507","journal-title":"Mol Immunol"},{"key":"4201_CR24","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1016\/j.bbrc.2013.09.088","volume":"440","author":"G Yin","year":"2013","unstructured":"Yin G, Qin M, Liu X, Suo J, Tang X, Tao G, Han Q, Suo X, Wu W (2013) An Eimeria vaccine candidate based on Eimeria tenella immune mapped protein 1 and the TLR-5 agonist Salmonella typhimurium, FliC flagellin. Biochem Biophys Res Commun 440:437\u2013442","journal-title":"Biochem Biophys Res Commun"},{"key":"4201_CR25","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1128\/IAI.02811-14","volume":"83","author":"E Ramos-Sevillano","year":"2015","unstructured":"Ramos-Sevillano E, Urzainqui A, Campuzano S, Moscoso M, Gonz\u00e1lez-Camacho F, Domenech M, Rodr\u00edguez de C\u00f3rdoba S, S\u00e1nchez-Madrid F, Brown JS, Garc\u00eda E, Yuste J (2015) Pleiotropic effects of cell wall amidase LytA on Streptococcus pneumoniae sensitivity to the host immune response. Infect Immun 83:591\u2013603","journal-title":"Infect Immun"},{"key":"4201_CR26","doi-asserted-by":"publisher","first-page":"5761","DOI":"10.1016\/j.vaccine.2012.06.086","volume":"30","author":"DN Taylor","year":"2012","unstructured":"Taylor DN, Treanor JJ, Sheldon EA, Johnson C, Umlauf S, Song L, Kavita U, Liu G, Tussey L, Ozer K, Hofstaetter T, Shaw A (2012) Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response. Vaccine 30:5761\u20135769","journal-title":"Vaccine"},{"key":"4201_CR27","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1089\/vim.2009.0107","volume":"23","author":"KN Delaney","year":"2010","unstructured":"Delaney KN, Phipps JP, Johnson JB, Mizel SB (2010) A recombinant flagellin-poxvirus fusion protein vaccine elicits complement-dependent protection against respiratory challenge with vaccinia virus in mice. Viral Immunol 23:201\u2013210","journal-title":"Viral Immunol"},{"key":"4201_CR28","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1006\/cimm.2000.1703","volume":"204","author":"CY Koh","year":"2000","unstructured":"Koh CY, Yuan D (2000) The functional relevance of NK-cell-mediated upregulation of antigen-specific IgG2a responses. Cell Immunol 204:135\u2013142","journal-title":"Cell Immunol"},{"key":"4201_CR29","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.cellimm.2014.09.003","volume":"292","author":"C Wang","year":"2014","unstructured":"Wang C, Li X, Wu T, Li D, Niu M, Wang Y, Zhang C, Cheng X, Chen P (2014) Bursin-like peptide (BLP) enhances H9N2 influenza vaccine induced humoral and cell mediated immune responses. Cell Immunol 292:57\u201364","journal-title":"Cell Immunol"},{"key":"4201_CR30","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1128\/CVI.00156-06","volume":"13","author":"VC Huber","year":"2006","unstructured":"Huber VC, Mckeon RM, Brackin MN, Miller LA, Keating R, Brown SA, Makarova N, Perez DR, Macdonald GH, McCullers JA (2006) Distinct contributions of vaccine-induced immunoglobulin G1 (IgG1) and IgG2a antibodies to protective immunity against Influenza. Clin Vaccine Immunol 13:981\u2013990","journal-title":"Clin Vaccine Immunol"},{"key":"4201_CR31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12896-015-0195-z","volume":"15","author":"L Song","year":"2015","unstructured":"Song L, Xiong D, Kang X, Yang Y, Wang J, Guo Y, Xu H, Chen S, Peng D, Pan Z, Jiao X (2015) An avian influenza A (H7N9) virus vaccine candidate based on the fusion protein of hemagglutinin globular head and salmonella typhimurium, flagellin. BMC Biotechnol 15:1\u20138","journal-title":"BMC Biotechnol"},{"key":"4201_CR32","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.vaccine.2010.11.002","volume":"29","author":"B Dziadek","year":"2011","unstructured":"Dziadek B, Gatkowska J, Brzostek A, Dziadek J, Dzitko K, Grzybowski M, Dlugonska H (2011) Evaluation of three recombinant multi-antigenic vaccines composed of surface and secretory antigens of Toxoplasma gondii in murine models of experimental toxoplasmosis. Vaccine 29:821\u2013830","journal-title":"Vaccine"},{"key":"4201_CR33","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1111\/hae.12522","volume":"21","author":"BK Sack","year":"2015","unstructured":"Sack BK, Wang X, Sherman A, Rogers GL, Markusic DM (2015) Immune responses to human factor IX in haemophilia B mice of different genetic backgrounds are distinct and modified by TLR4. Haemophilia 21:133\u2013139","journal-title":"Haemophilia"},{"key":"4201_CR34","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1007\/s00262-007-0384-2","volume":"57","author":"MC Labarthe","year":"2008","unstructured":"Labarthe MC, Theocharous P, Russell N, Todryk S, Bangma C, Thraves P, Dalgleish AG, Whelan MA (2008) A novel murine model of allogeneic vaccination against prostate cancer. Cancer Immunol Immunother 57:453\u2013465","journal-title":"Cancer Immunol Immunother"},{"key":"4201_CR35","doi-asserted-by":"publisher","first-page":"2356","DOI":"10.1128\/IAI.00054-09","volume":"77","author":"ET Weimer","year":"2009","unstructured":"Weimer ET, Lu H, Kock ND, Wozniak DJ, Mizel SB (2009) A fusion protein vaccine containing OprF epitope 8, OprI and type A and B flagellins promotes enhanced clearance of nonmucoid pseudomonas aeruginosa. Infect Immun 77:2356\u20132366","journal-title":"Infect Immun"},{"key":"4201_CR36","doi-asserted-by":"publisher","first-page":"6833","DOI":"10.1016\/j.vaccine.2012.09.013","volume":"30","author":"G Liu","year":"2012","unstructured":"Liu G, Song L, Reiserova L, Trivedi U, Li H, Liu X, Noah D, Hou F, Weaver B, Tussey L (2012) Flagellin-HA vaccines protect ferrets and mice against H5N1 highly pathogenic avian influenza virus (HPAIV) infections. Vaccine 30:6833\u20136838","journal-title":"Vaccine"},{"key":"4201_CR37","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1099\/0022-1317-75-7-1735","volume":"75","author":"D Tewari","year":"1994","unstructured":"Tewari D, Whalley JM, Love DN, Field HJ (1994) Characterization of immune responses to baculovirus-expressed equine herpesvirus type 1 glycoproteins D and H in a murine model. J Gen Virol 75:1735\u20131741","journal-title":"J Gen Virol"},{"key":"4201_CR38","doi-asserted-by":"publisher","first-page":"482","DOI":"10.1006\/viro.2000.0197","volume":"268","author":"Y Zhang","year":"2000","unstructured":"Zhang Y, Smith PM, Jennings SR, O\u2019Callaghan DJ (2000) Quantitation of virus-specific classes of antibodies following immunization of mice with attenuated equine herpesvirus 1 and viral glycoprotein D. Virology 268:482\u2013492","journal-title":"Virology"},{"key":"4201_CR39","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S0378-1135(00)00237-6","volume":"76","author":"KM Ruitenberg","year":"2000","unstructured":"Ruitenberg KM, Love DN, Gilkerson JR, Wellington JE, Whalley JM (2000) Equine herpesvirus 1 (EHV-1) glycoprotein D DNA inoculation in horses with pre-existing EHV-1\/EHV-4 antibody. Vet Microbiol 76:117\u2013127","journal-title":"Vet Microbiol"},{"key":"4201_CR40","doi-asserted-by":"publisher","first-page":"1367","DOI":"10.1016\/S0264-410X(99)00400-4","volume":"18","author":"KM Ruitenberg","year":"2000","unstructured":"Ruitenberg KM, Walker C, Love DN, Wellington JE, Whalley JM (2000) A prime-boost immunization strategy with DNA and recombinant baculovirus-expressed protein enhances protective immunogenicity of glycoprotein D of equine herpesvirus 1 in naive and infection-primed mice. Vaccine 18:1367\u20131373","journal-title":"Vaccine"},{"key":"4201_CR41","unstructured":"Allen GP, Kydd JH, Slater JD, Smith KC (1999) Recent advances in understanding the pathogenesis, latency and immunology of EHV-1 abortion (invited review). In: Proceedings of the 8th international conference on equine infectious diseases, Newmarket, pp\u00a0129\u2013146"},{"key":"4201_CR42","doi-asserted-by":"publisher","first-page":"54","DOI":"10.3201\/eid0501.990107","volume":"5","author":"L Zeitlin","year":"1999","unstructured":"Zeitlin L, Cone RA, Whaley KJ (1999) Using monoclonal antibodies to prevent mucosal transmission of epidemic infectious diseases. Emerg Infect Dis 5:54","journal-title":"Emerg Infect Dis"},{"key":"4201_CR43","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1016\/0042-6822(92)90755-E","volume":"188","author":"BA Israel","year":"1992","unstructured":"Israel BA, Herber R, Gao Y (1992) Induction of a mucosal barrier to bovine herpesvirus 1 replication in cattle. Virology 188:256\u2013264","journal-title":"Virology"},{"key":"4201_CR44","doi-asserted-by":"publisher","first-page":"651","DOI":"10.2746\/042516401776249318","volume":"33","author":"CC Breathnach","year":"2001","unstructured":"Breathnach CC, Yeargan MR, Sheoran AS, Allen GP (2001) The mucosal humoral immune response of the horse to infective challenge and vaccination with equine herpesvirus-1 antigens. Equine Vet J 33:651\u2013657","journal-title":"Equine Vet J"},{"key":"4201_CR45","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1016\/j.jcpa.2014.06.003","volume":"151","author":"NA Fuentealba","year":"2014","unstructured":"Fuentealba NA, Zanuzzi CN, Scrochi MR, Sguazza GH, Bravi ME, Paz VCDL, Corva SG, Portiansky EL, Gimeno EJ, Barbeito CG, Galosi CM (2014) Protective effects of intranasal immunization with recombinant glycoprotein d in pregnant BALB\/c mice challenged with different strains of equine herpesvirus 1. J Comp Pathol 151:384\u2013393","journal-title":"J Comp Pathol"},{"key":"4201_CR46","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1128\/IAI.74.1.694-702.2006","volume":"74","author":"SE Lee","year":"2006","unstructured":"Lee SE, Kim SY, Jeong BC, Kim YR, Bae SJ, Ahn OS, Lee JJ, Song HC, Kim JM, Choy HE, Chung SS, Kweon MN, Rhee JH (2006) A bacterial flagellin, vibrio vulnificus FlaB, has a strong mucosal adjuvant activity to induce protective immunity. Infect Immun 74:694\u2013702","journal-title":"Infect Immun"},{"key":"4201_CR47","doi-asserted-by":"publisher","first-page":"4350","DOI":"10.1128\/IAI.00263-13","volume":"81","author":"D Carapau","year":"2013","unstructured":"Carapau D, Mitchell R, Nacer A, Shaw A, Othoro C, Frevert U, Nardin E (2013) Protective humoral immunity elicited by a needle-free malaria vaccine comprised of a chimeric plasmodium falciparum circumsporozoite protein and a Toll-like receptor 5 agonist, flagellin. Infect Immun 81:4350\u20134362","journal-title":"Infect Immun"}],"container-title":["Archives of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-019-04201-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00705-019-04201-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-019-04201-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T16:41:55Z","timestamp":1684860115000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00705-019-04201-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,19]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2019,5,1]]}},"alternative-id":["4201"],"URL":"https:\/\/doi.org\/10.1007\/s00705-019-04201-4","relation":{},"ISSN":["0304-8608","1432-8798"],"issn-type":[{"value":"0304-8608","type":"print"},{"value":"1432-8798","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,19]]},"assertion":[{"value":"18 June 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 March 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no competing financial interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures involving animals were approved by the Ethics Committee for Animal Experiments at the Xinjiang Agricultural University. All animal experiments were conducted in strict accordance with international, national, and institutional guidelines for the use and care of animals. All authors contributed to this work and agreed to its publication.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}