{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T21:32:57Z","timestamp":1769549577220,"version":"3.49.0"},"reference-count":74,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T00:00:00Z","timestamp":1586131200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T00:00:00Z","timestamp":1586131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Virol"],"published-print":{"date-parts":[[2020,6]]},"DOI":"10.1007\/s00705-020-04617-3","type":"journal-article","created":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T19:03:46Z","timestamp":1586199826000},"page":"1321-1331","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Canine distemper virus induces downregulation of GABAA,GABAB, and GAT1 expression in brain tissue of dogs"],"prefix":"10.1007","volume":"165","author":[{"given":"Selim","family":"\u00c7omakli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sel\u00e7uk","family":"\u00d6zdemir","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015e\u00fckr\u00fc","family":"De\u011firmen\u00e7ay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,4,6]]},"reference":[{"issue":"3","key":"4617_CR1","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/j.pharmthera.2006.03.006","volume":"110","author":"B Bettler","year":"2006","unstructured":"Bettler B, Tiao JY (2006) Molecular diversity, trafficking and subcellular localization of GABAB receptors. Pharmacol Therap 110(3):533\u2013543. https:\/\/doi.org\/10.1016\/j.pharmthera.2006.03.006","journal-title":"Pharmacol Therap"},{"issue":"1","key":"4617_CR2","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.coph.2005.10.002","volume":"6","author":"NG Bowery","year":"2006","unstructured":"Bowery NG (2006) GABAB receptor: a site of therapeutic benefit. Curr Opin Pharmacol 6(1):37\u201343. https:\/\/doi.org\/10.1016\/j.coph.2005.10.002","journal-title":"Curr Opin Pharmacol"},{"issue":"4","key":"4617_CR3","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1006\/mcne.2000.0908","volume":"16","author":"A Couve","year":"2000","unstructured":"Couve A, Moss SJ, Pangalos MN (2000) GABAB receptors: a new paradigm in G protein signaling. Mol Cell Neurosci 16(4):296\u2013312. https:\/\/doi.org\/10.1006\/mcne.2000.0908","journal-title":"Mol Cell Neurosci"},{"issue":"3","key":"4617_CR4","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/j.conb.2007.04.001","volume":"17","author":"D Ulrich","year":"2007","unstructured":"Ulrich D, Bettler B (2007) GABA(B) receptors: synaptic functions and mechanisms of diversity. Curr Opin Neurobiol 17(3):298\u2013303. https:\/\/doi.org\/10.1016\/j.conb.2007.04.001","journal-title":"Curr Opin Neurobiol"},{"issue":"2\u20133","key":"4617_CR5","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/S0165-0173(98)00052-6","volume":"29","author":"AK Mehta","year":"1999","unstructured":"Mehta AK, Ticku MK (1999) An update on GABAA receptors. Brain Res Brain Res Rev 29(2\u20133):196\u2013217","journal-title":"Brain Res Brain Res Rev"},{"issue":"3","key":"4617_CR6","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1124\/pr.108.00505","volume":"60","author":"RW Olsen","year":"2008","unstructured":"Olsen RW, Sieghart W (2008) International Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. Update. Pharmacol Rev 60(3):243\u2013260. https:\/\/doi.org\/10.1124\/pr.108.00505","journal-title":"Pharmacol Rev"},{"issue":"7","key":"4617_CR7","doi-asserted-by":"publisher","first-page":"836","DOI":"10.1002\/hipo.10221","volume":"14","author":"G Lopez-Bendito","year":"2004","unstructured":"Lopez-Bendito G, Shigemoto R, Kulik A, Vida I, Fairen A, Lujan R (2004) Distribution of metabotropic GABA receptor subunits GABAB1a\/b and GABAB2 in the rat hippocampus during prenatal and postnatal development. Hippocampus 14(7):836\u2013848. https:\/\/doi.org\/10.1002\/hipo.10221","journal-title":"Hippocampus"},{"issue":"6","key":"4617_CR8","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1006\/mcne.2001.0995","volume":"17","author":"HM Prosser","year":"2001","unstructured":"Prosser HM, Gill CH, Hirst WD, Grau E, Robbins M, Calver A, Soffin EM, Farmer CE, Lanneau C, Gray J, Schenck E, Warmerdam BS, Clapham C, Reavill C, Rogers DC, Stean T, Upton N, Humphreys K, Randall A, Geppert M, Davies CH, Pangalos MN (2001) Epileptogenesis and enhanced prepulse inhibition in GABA(B1)-deficient mice. Mol Cell Neurosci 17(6):1059\u20131070. https:\/\/doi.org\/10.1006\/mcne.2001.0995","journal-title":"Mol Cell Neurosci"},{"issue":"1","key":"4617_CR9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/s0896-6273(01)00345-2","volume":"31","author":"V Schuler","year":"2001","unstructured":"Schuler V, Luscher C, Blanchet C, Klix N, Sansig G, Klebs K, Schmutz M, Heid J, Gentry C, Urban L, Fox A, Spooren W, Jaton AL, Vigouret J, Pozza M, Kelly PH, Mosbacher J, Froestl W, Kaslin E, Korn R, Bischoff S, Kaupmann K, van der Putten H, Bettler B (2001) Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron 31(1):47\u201358. https:\/\/doi.org\/10.1016\/s0896-6273(01)00345-2","journal-title":"Neuron"},{"issue":"4","key":"4617_CR10","doi-asserted-by":"publisher","first-page":"1189","DOI":"10.1523\/JNEUROSCI.21-04-01189.2001","volume":"21","author":"A Pagano","year":"2001","unstructured":"Pagano A, Rovelli G, Mosbacher J, Lohmann T, Duthey B, Stauffer D, Ristig D, Schuler V, Meigel I, Lampert C, Stein T, Prezeau L, Blahos J, Pin J, Froestl W, Kuhn R, Heid J, Kaupmann K, Bettler B (2001) C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors. J Neurosci 21(4):1189\u20131202","journal-title":"J Neurosci"},{"issue":"10","key":"4617_CR11","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/S0165-6147(99)01383-8","volume":"20","author":"FH Marshall","year":"1999","unstructured":"Marshall FH, Jones KA, Kaupmann K, Bettler B (1999) GABAB receptors\u2014the first 7TM heterodimers. Trends Pharmacol Sci 20(10):396\u2013399","journal-title":"Trends Pharmacol Sci"},{"issue":"6","key":"4617_CR12","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1001\/archneur.1980.00500550054006","volume":"37","author":"NB Manyam","year":"1980","unstructured":"Manyam NB, Katz L, Hare TA, Gerber JC, Grossman MH (1980) Levels of \u03b3-aminobutyric acid in cerebrospinal fluid in various neurologic disorders. Arch Neurol 37(6):352\u2013355","journal-title":"Arch Neurol"},{"issue":"4","key":"4617_CR13","doi-asserted-by":"publisher","first-page":"249","DOI":"10.3109\/13550289609146888","volume":"2","author":"VJ Sanders","year":"1996","unstructured":"Sanders VJ, Felisan S, Waddell A, Tourtellotte WW (1996) Detection of herpesviridae in postmortem multiple sclerosis brain tissue and controls by polymerase chain reaction. J Neurovirol 2(4):249\u2013258","journal-title":"J Neurovirol"},{"issue":"4","key":"4617_CR14","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1001\/archneur.55.4.513","volume":"55","author":"R Gade-Andavolu","year":"1998","unstructured":"Gade-Andavolu R, MacMurray JP, Blake H, Muhleman D, Tourtellotte W, Comings DE (1998) Association between the gamma-aminobutyric acid A3 receptor gene and multiple sclerosis. Arch Neurol 55(4):513\u2013516. https:\/\/doi.org\/10.1001\/archneur.55.4.513","journal-title":"Arch Neurol"},{"key":"4617_CR15","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.eplepsyres.2017.08.013","volume":"137","author":"JQ Kang","year":"2017","unstructured":"Kang JQ (2017) Defects at the crossroads of GABAergic signaling in generalized genetic epilepsies. Epilepsy Res 137:9\u201318. https:\/\/doi.org\/10.1016\/j.eplepsyres.2017.08.013","journal-title":"Epilepsy Res"},{"key":"4617_CR16","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1007\/978-3-319-55769-4_7","volume":"16","author":"MEK Lie","year":"2017","unstructured":"Lie MEK, Al-Khawaja A, Damgaard M, Haugaard AS, Schousboe A, Clarkson AN, Wellendorph P (2017) Glial GABA transporters as modulators of \u0131nhibitory signalling in epilepsy and stroke. Adv Neurobiol 16:137\u2013167. https:\/\/doi.org\/10.1007\/978-3-319-55769-4_7","journal-title":"Adv Neurobiol"},{"key":"4617_CR17","doi-asserted-by":"publisher","first-page":"4159","DOI":"10.1038\/ncomms5159","volume":"5","author":"Z Wu","year":"2014","unstructured":"Wu Z, Guo Z, Gearing M, Chen G (2014) Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer\u2019s [corrected] disease model. Nat Commun 5:4159. https:\/\/doi.org\/10.1038\/ncomms5159","journal-title":"Nat Commun"},{"issue":"5","key":"4617_CR18","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1016\/j.ajhg.2015.02.016","volume":"96","author":"GL Carvill","year":"2015","unstructured":"Carvill GL, McMahon JM, Schneider A, Zemel M, Myers CT, Saykally J, Nguyen J, Robbiano A, Zara F, Specchio N, Mecarelli O, Smith RL, Leventer RJ, Moller RS, Nikanorova M, Dimova P, Jordanova A, Petrou S, Helbig I, Striano P, Weckhuysen S, Berkovic SF, Scheffer IE, Mefford HC (2015) Mutations in the GABA transporter SLC6A1 cause epilepsy with myoclonic\u2013atonic seizures. Am J Hum Genet 96(5):808\u2013815. https:\/\/doi.org\/10.1016\/j.ajhg.2015.02.016","journal-title":"Am J Hum Genet"},{"issue":"2","key":"4617_CR19","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1111\/epi.13986","volume":"59","author":"KM Johannesen","year":"2018","unstructured":"Johannesen KM, Gardella E, Linnankivi T, Courage C, de Saint Martin A, Lehesjoki AE, Mignot C, Afenjar A, Lesca G, Abi-Warde MT, Chelly J, Piton A, Merritt JL 2nd, Rodan LH, Tan WH, Bird LM, Nespeca M, Gleeson JG, Yoo Y, Choi M, Chae JH, Czapansky-Beilman D, Reichert SC, Pendziwiat M, Verhoeven JS, Schelhaas HJ, Devinsky O, Christensen J, Specchio N, Trivisano M, Weber YG, Nava C, Keren B, Doummar D, Schaefer E, Hopkins S, Dubbs H, Shaw JE, Pisani L, Myers CT, Tang S, Tang S, Pal DK, Millichap JJ, Carvill GL, Helbig KL, Mecarelli O, Striano P, Helbig I, Rubboli G, Mefford HC, Moller RS (2018) Defining the phenotypic spectrum of SLC6A1 mutations. Epilepsia 59(2):389\u2013402. https:\/\/doi.org\/10.1111\/epi.13986","journal-title":"Epilepsia"},{"issue":"12","key":"4617_CR20","doi-asserted-by":"publisher","first-page":"6279","DOI":"10.1128\/jvi.00050-09","volume":"83","author":"S Pillet","year":"2009","unstructured":"Pillet S, von Messling V (2009) Canine distemper virus selectively inhibits apoptosis progression in infected immune cells. J Virol 83(12):6279\u20136287. https:\/\/doi.org\/10.1128\/jvi.00050-09","journal-title":"J Virol"},{"issue":"18","key":"4617_CR21","doi-asserted-by":"publisher","first-page":"10207","DOI":"10.1128\/jvi.00824-12","volume":"86","author":"W Pratakpiriya","year":"2012","unstructured":"Pratakpiriya W, Seki F, Otsuki N, Sakai K, Fukuhara H, Katamoto H, Hirai T, Maenaka K, Techangamsuwan S, Lan NT, Takeda M, Yamaguchi R (2012) Nectin4 is an epithelial cell receptor for canine distemper virus and involved in neurovirulence. J Virol 86(18):10207\u201310210. https:\/\/doi.org\/10.1128\/jvi.00824-12","journal-title":"J Virol"},{"issue":"1","key":"4617_CR22","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1556\/avet.56.2008.1.12","volume":"56","author":"T Guvenc","year":"2008","unstructured":"Guvenc T, Yarim M, Gulbahar M, Kabak Y (2008) Immunohistochemical distribution of alpha B-crystallin in the cerebellum of dogs infected with canine distemper virus. Acta Vet Hung 56(1):117\u2013123","journal-title":"Acta Vet Hung"},{"issue":"7\u20138","key":"4617_CR23","first-page":"301","volume":"123","author":"M Yarim","year":"2010","unstructured":"Yarim M, Gulbahar MY, Guvenc T, Karahan S, Harada N, Kabak YB, Karayigit MO (2010) Aromatase expression in the cerebellum of the dog infected with canine distemper virus. Berl Munch Tierarztl Wochenschr 123(7\u20138):301\u2013306","journal-title":"Berl Munch Tierarztl Wochenschr"},{"key":"4617_CR24","doi-asserted-by":"publisher","first-page":"39954","DOI":"10.1038\/srep39954","volume":"7","author":"N Zhao","year":"2017","unstructured":"Zhao N, Li M, Luo J, Wang S, Liu S, Wang S, Lyu W, Chen L, Su W, Ding H, He H (2017) Impacts of canine distemper virus infection on the giant panda population from the perspective of gut microbiota. Sci Rep 7:39954. https:\/\/doi.org\/10.1038\/srep39954","journal-title":"Sci Rep"},{"key":"4617_CR25","doi-asserted-by":"publisher","first-page":"27518","DOI":"10.1038\/srep27518","volume":"6","author":"N Feng","year":"2016","unstructured":"Feng N, Yu Y, Wang T, Wilker P, Wang J, Li Y, Sun Z, Gao Y, Xia X (2016) Fatal canine distemper virus infection of giant pandas in China. Sci Rep 6:27518. https:\/\/doi.org\/10.1038\/srep27518","journal-title":"Sci Rep"},{"issue":"1\u20132","key":"4617_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.vetimm.2008.09.023","volume":"127","author":"A Beineke","year":"2009","unstructured":"Beineke A, Puff C, Seehusen F, Baumgartner W (2009) Pathogenesis and immunopathology of systemic and nervous canine distemper. Vet Immunol Immunopathol 127(1\u20132):1\u201318. https:\/\/doi.org\/10.1016\/j.vetimm.2008.09.023","journal-title":"Vet Immunol Immunopathol"},{"issue":"8","key":"4617_CR27","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.3201\/eid1708.101153","volume":"17","author":"W Qiu","year":"2011","unstructured":"Qiu W, Zheng Y, Zhang S, Fan Q, Liu H, Zhang F, Wang W, Liao G, Hu R (2011) Canine distemper outbreak in rhesus monkeys, China. Emerg \u0130nfect Dis 17(8):1541\u20131543. https:\/\/doi.org\/10.3201\/eid1708.101153","journal-title":"Emerg \u0130nfect Dis"},{"issue":"6564","key":"4617_CR28","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1038\/379441a0","volume":"379","author":"ME Roelke-Parker","year":"1996","unstructured":"Roelke-Parker ME, Munson L, Packer C, Kock R, Cleaveland S, Carpenter M, O\u2019Brien SJ, Pospischil A, Hofmann-Lehmann R, Lutz H, Mwamengele GL, Mgasa MN, Machange GA, Summers BA, Appel MJ (1996) A canine distemper virus epidemic in Serengeti lions (Panthera leo). Nature 379(6564):441\u2013445. https:\/\/doi.org\/10.1038\/379441a0","journal-title":"Nature"},{"issue":"15","key":"4617_CR29","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1136\/vr.141.15.380","volume":"141","author":"C Ek-Kommonen","year":"1997","unstructured":"Ek-Kommonen C, Sihvonen L, Pekkanen K, Rikula U, Nuotio L (1997) Outbreak off canine distemper in vaccinated dogs in Finland. Vet Rec 141(15):380\u2013383. https:\/\/doi.org\/10.1136\/vr.141.15.380","journal-title":"Vet Rec"},{"issue":"3","key":"4617_CR30","doi-asserted-by":"publisher","first-page":"385","DOI":"10.7589\/0090-3558-24.3.385","volume":"24","author":"ES Williams","year":"1988","unstructured":"Williams ES, Thorne ET, Appel MJ, Belitsky DW (1988) Canine distemper in black-footed ferrets (Mustela nigripes) from Wyoming. J Wildl Dis 24(3):385\u2013398. https:\/\/doi.org\/10.7589\/0090-3558-24.3.385","journal-title":"J Wildl Dis"},{"issue":"9","key":"4617_CR31","first-page":"1616","volume":"50","author":"M Blixenkrone-Moller","year":"1989","unstructured":"Blixenkrone-Moller M (1989) Detection of intracellular canine distemper virus antigen in mink inoculated with an attenuated or a virulent strain of canine distemper virus. Am J Vet Res 50(9):1616\u20131620","journal-title":"Am J Vet Res"},{"issue":"1\u20132","key":"4617_CR32","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/s0378-1135(99)00080-2","volume":"69","author":"T Barrett","year":"1999","unstructured":"Barrett T (1999) Morbillivirus infections, with special emphasis on morbilliviruses of carnivores. Vet Microbiol 69(1\u20132):3\u201313. https:\/\/doi.org\/10.1016\/s0378-1135(99)00080-2","journal-title":"Vet Microbiol"},{"key":"4617_CR33","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1007\/0-387-25518-4_51","volume-title":"Experimental models of multiple sclerosis","author":"W Baumg\u00e4rtner","year":"2005","unstructured":"Baumg\u00e4rtner W, Alldinger S (2005) The pathogenesis of canine distemper virus induced demyelination a biphasic process. In: Lavi LE, Constantinescu CS (eds) Experimental models of multiple sclerosis. Springer, New York, pp 871\u2013888"},{"issue":"1","key":"4617_CR34","doi-asserted-by":"publisher","first-page":"16555","DOI":"10.1038\/s41598-018-32733-3","volume":"8","author":"J Tian","year":"2018","unstructured":"Tian J, Dang H, Wallner M, Olsen R, Kaufman DL (2018) Homotaurine, a safe blood-brain barrier permeable GABAA-R-specific agonist, ameliorates disease in mouse models of multiple sclerosis. Sci Rep 8(1):16555. https:\/\/doi.org\/10.1038\/s41598-018-32733-3","journal-title":"Sci Rep"},{"key":"4617_CR35","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24737","author":"J Van Schependom","year":"2019","unstructured":"Van Schependom J, Vidaurre D, Costers L, Sjogard M, D\u2019Hooghe MB, D\u2019Haeseleer M, Wens V, De Tiege X, Goldman S, Woolrich M, Nagels G (2019) Altered transient brain dynamics in multiple sclerosis: treatment or pathology? Hum Brain Mapp. https:\/\/doi.org\/10.1002\/hbm.24737","journal-title":"Hum Brain Mapp"},{"issue":"1","key":"4617_CR36","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1186\/s13148-019-0678-1","volume":"11","author":"L Kular","year":"2019","unstructured":"Kular L, Needhamsen M, Adzemovic MZ, Kramarova T, Gomez-Cabrero D, Ewing E, Piket E, Tegner J, Beck S, Piehl F, Brundin L, Jagodic M (2019) Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis. Clin Epigenet 11(1):86. https:\/\/doi.org\/10.1186\/s13148-019-0678-1","journal-title":"Clin Epigenet"},{"issue":"6","key":"4617_CR37","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1093\/jnen\/nlz028","volume":"78","author":"S Kiljan","year":"2019","unstructured":"Kiljan S, Prins M, Baselmans BM, Bol J, Schenk GJ, van Dam AM (2019) Enhanced GABAergic \u0131mmunoreactivity in hippocampal neurons and astroglia of multiple sclerosis patients. J Neuropathol Exp Neurol 78(6):480\u2013491. https:\/\/doi.org\/10.1093\/jnen\/nlz028","journal-title":"J Neuropathol Exp Neurol"},{"key":"4617_CR38","doi-asserted-by":"publisher","DOI":"10.1002\/glia.23618","author":"C Habermacher","year":"2019","unstructured":"Habermacher C, Angulo MC, Benamer N (2019) Glutamate versus GABA in neuron-oligodendroglia communication. Glia. https:\/\/doi.org\/10.1002\/glia.23618","journal-title":"Glia"},{"issue":"1","key":"4617_CR39","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1159\/000495425","volume":"26","author":"P Hundehege","year":"2018","unstructured":"Hundehege P, Fernandez-Orth J, Romer P, Ruck T, Muntefering T, Eichler S, Cerina M, Epping L, Albrecht S, Menke AF, Birkner K, Gobel K, Budde T, Zipp F, Wiendl H, Gorji A, Bittner S, Meuth SG (2018) Targeting voltage-dependent calcium channels with pregabalin exerts a direct neuroprotective effect in an animal model of multiple sclerosis. Neuro-Signals 26(1):77\u201393. https:\/\/doi.org\/10.1159\/000495425","journal-title":"Neuro-Signals"},{"key":"4617_CR40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/pathogens8010026","volume":"8","author":"S Comakli","year":"2019","unstructured":"Comakli S, Ozdemir S (2019) Comparative evaluation of the \u0131mmune responses in cattle mammary tissues naturally \u0131nfected with bovine parainfluenza virus Type 3 and bovine alphaherpesvirus-1. Pathogens (Basel, Switzerland) 8:1. https:\/\/doi.org\/10.3390\/pathogens8010026","journal-title":"Pathogens (Basel, Switzerland)"},{"issue":"3","key":"4617_CR41","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/j.repbio.2018.06.006","volume":"18","author":"S Ozdemir","year":"2018","unstructured":"Ozdemir S, Comakli S (2018) Investigation of the interaction between bta-miR-222 and the estrogen receptor alpha gene in the bovine ovarium. Reprod Biol 18(3):259\u2013266. https:\/\/doi.org\/10.1016\/j.repbio.2018.06.006","journal-title":"Reprod Biol"},{"key":"4617_CR42","first-page":"211","volume":"34","author":"DF Liu","year":"2011","unstructured":"Liu DF, Jiang YT, Yang TK, Lin H, Liu CG, Chai HL,\u00a0Wang C, Cui Y, Jiang XF, Ma XQ, Liu DC, Hua YP, Qu LD, Zhang HY\u00a0(2011) Establishment of the duplex PCR for the detection of canine distemper virus and canine parvovirus. Chin Pre Vet Med 34:211\u2013213","journal-title":"Chin Pre Vet Med"},{"issue":"7","key":"4617_CR43","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1292\/jvms.17-0442","volume":"81","author":"D Liu","year":"2019","unstructured":"Liu D, Liu F, Guo D, Hu X, Li Z, Li Z, Ma J, Liu C (2019) One-step triplex PCR\/RT-PCR to detect canine distemper virus, canine parvovirus and canine kobuvirus. J Vet Med Sci 81(7):1040\u20131042. https:\/\/doi.org\/10.1292\/jvms.17-0442","journal-title":"J Vet Med Sci"},{"issue":"4","key":"4617_CR44","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (San Diego, Calif) 25(4):402\u2013408. https:\/\/doi.org\/10.1006\/meth.2001.1262","journal-title":"Methods (San Diego, Calif)"},{"issue":"3","key":"4617_CR45","doi-asserted-by":"publisher","first-page":"306","DOI":"10.3906\/vet-1812-85","volume":"43","author":"S \u00c7omakl\u0131","year":"2019","unstructured":"\u00c7omakl\u0131 S, Sa\u011flam YS, Timurkan M\u00d6 (2019) Comparative detection of bovine herpesvirus-1 using antigen ELISA, immunohistochemistry and immunofluorescence methods in cattle with pneumonia. Turk J Vet Anim Sci 43(3):306\u2013313","journal-title":"Turk J Vet Anim Sci"},{"issue":"1","key":"4617_CR46","doi-asserted-by":"publisher","first-page":"11689","DOI":"10.1038\/s41598-019-48146-9","volume":"9","author":"J Klemens","year":"2019","unstructured":"Klemens J, Ciurkiewicz M, Chludzinski E, Iseringhausen M, Klotz D, Pfankuche VM, Ulrich R, Herder V, Puff C, Baumgartner W, Beineke A (2019) Neurotoxic potential of reactive astrocytes in canine distemper demyelinating leukoencephalitis. Sci Rep 9(1):11689. https:\/\/doi.org\/10.1038\/s41598-019-48146-9","journal-title":"Sci Rep"},{"issue":"3","key":"4617_CR47","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1111\/j.1750-3639.2009.00332.x","volume":"20","author":"F Seehusen","year":"2010","unstructured":"Seehusen F, Baumgartner W (2010) Axonal pathology and loss precede demyelination and accompany chronic lesions in a spontaneously occurring animal model of multiple sclerosis. Brain Pathol (Zurich, Switzerland) 20(3):551\u2013559. https:\/\/doi.org\/10.1111\/j.1750-3639.2009.00332.x","journal-title":"Brain Pathol (Zurich, Switzerland)"},{"issue":"1\u20132","key":"4617_CR48","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.vetimm.2012.04.005","volume":"147","author":"I Spitzbarth","year":"2012","unstructured":"Spitzbarth I, Baumgartner W, Beineke A (2012) The role of pro- and anti-inflammatory cytokines in the pathogenesis of spontaneous canine CNS diseases. Vet Immunol Immunopathol 147(1\u20132):6\u201324. https:\/\/doi.org\/10.1016\/j.vetimm.2012.04.005","journal-title":"Vet Immunol Immunopathol"},{"issue":"3","key":"4617_CR49","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1002\/glia.22270","volume":"60","author":"I Imbschweiler","year":"2012","unstructured":"Imbschweiler I, Seehusen F, Peck CT, Omar M, Baumgartner W, Wewetzer K (2012) Increased p75 neurotrophin receptor expression in the canine distemper virus model of multiple sclerosis identifies aldynoglial Schwann cells that emerge in response to axonal damage. Glia 60(3):358\u2013371. https:\/\/doi.org\/10.1002\/glia.22270","journal-title":"Glia"},{"issue":"6","key":"4617_CR50","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1002\/glia.20958","volume":"58","author":"M Domercq","year":"2010","unstructured":"Domercq M, Perez-Samartin A, Aparicio D, Alberdi E, Pampliega O, Matute C (2010) P2X7 receptors mediate ischemic damage to oligodendrocytes. Glia 58(6):730\u2013740. https:\/\/doi.org\/10.1002\/glia.20958","journal-title":"Glia"},{"issue":"5","key":"4617_CR51","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1002\/glia.22469","volume":"61","author":"C Li","year":"2013","unstructured":"Li C, Xiao L, Liu X, Yang W, Shen W, Hu C, Yang G, He C (2013) A functional role of NMDA receptor in regulating the differentiation of oligodendrocyte precursor cells and remyelination. Glia 61(5):732\u2013749. https:\/\/doi.org\/10.1002\/glia.22469","journal-title":"Glia"},{"issue":"6","key":"4617_CR52","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1002\/glia.22799","volume":"63","author":"J Fannon","year":"2015","unstructured":"Fannon J, Tarmier W, Fulton D (2015) Neuronal activity and AMPA-type glutamate receptor activation regulates the morphological development of oligodendrocyte precursor cells. Glia 63(6):1021\u20131035. https:\/\/doi.org\/10.1002\/glia.22799","journal-title":"Glia"},{"issue":"2","key":"4617_CR53","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1002\/glia.23093","volume":"65","author":"NB Hamilton","year":"2017","unstructured":"Hamilton NB, Clarke LE, Arancibia-Carcamo IL, Kougioumtzidou E, Matthey M, Karadottir R, Whiteley L, Bergersen LH, Richardson WD, Attwell D (2017) Endogenous GABA controls oligodendrocyte lineage cell number, myelination, and CNS internode length. Glia 65(2):309\u2013321. https:\/\/doi.org\/10.1002\/glia.23093","journal-title":"Glia"},{"key":"4617_CR54","doi-asserted-by":"publisher","first-page":"78","DOI":"10.3389\/fnmol.2018.00078","volume":"11","author":"JJ Miguel-Hidalgo","year":"2018","unstructured":"Miguel-Hidalgo JJ (2018) Molecular neuropathology of astrocytes and oligodendrocytes in alcohol use disorders. Front Mol Neurosci 11:78. https:\/\/doi.org\/10.3389\/fnmol.2018.00078","journal-title":"Front Mol Neurosci"},{"issue":"25","key":"4617_CR55","doi-asserted-by":"publisher","first-page":"16273","DOI":"10.1073\/pnas.232586699","volume":"99","author":"SY Yung","year":"2002","unstructured":"Yung SY, Gokhan S, Jurcsak J, Molero AE, Abrajano JJ, Mehler MF (2002) Differential modulation of BMP signaling promotes the elaboration of cerebral cortical GABAergic neurons or oligodendrocytes from a common sonic hedgehog-responsive ventral forebrain progenitor species. Proc Natl Acad Sci USA 99(25):16273\u201316278. https:\/\/doi.org\/10.1073\/pnas.232586699","journal-title":"Proc Natl Acad Sci USA"},{"key":"4617_CR56","doi-asserted-by":"publisher","first-page":"371","DOI":"10.3389\/fncel.2015.00371","volume":"9","author":"M Watanabe","year":"2015","unstructured":"Watanabe M, Fukuda A (2015) Development and regulation of chloride homeostasis in the central nervous system. Front Cell Neurosci 9:371. https:\/\/doi.org\/10.3389\/fncel.2015.00371","journal-title":"Front Cell Neurosci"},{"issue":"9","key":"4617_CR57","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1038\/nrd3502","volume":"10","author":"U Rudolph","year":"2011","unstructured":"Rudolph U, Knoflach F (2011) Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes. Nat Rev Drug Discovery 10(9):685\u2013697. https:\/\/doi.org\/10.1038\/nrd3502","journal-title":"Nat Rev Drug Discovery"},{"issue":"10","key":"4617_CR58","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1038\/nrn3819","volume":"15","author":"K Kaila","year":"2014","unstructured":"Kaila K, Price TJ, Payne JA, Puskarjov M, Voipio J (2014) Cation-chloride cotransporters in neuronal development, plasticity and disease. Nat Rev Neurosci 15(10):637\u2013654. https:\/\/doi.org\/10.1038\/nrn3819","journal-title":"Nat Rev Neurosci"},{"key":"4617_CR59","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.neuroscience.2011.04.010","volume":"191","author":"S Luchetti","year":"2011","unstructured":"Luchetti S, Huitinga I, Swaab DF (2011) Neurosteroid and GABA-A receptor alterations in Alzheimer\u2019s disease, Parkinson\u2019s disease and multiple sclerosis. Neuroscience 191:6\u201321. https:\/\/doi.org\/10.1016\/j.neuroscience.2011.04.010","journal-title":"Neuroscience"},{"issue":"1","key":"4617_CR60","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/0165-3806(93)90155-4","volume":"72","author":"JY Lim","year":"1993","unstructured":"Lim JY, Utzschneider DA, Sakatani K, Kocsis JD (1993) The attenuation of GABA sensitivity in the maturing myelin-deficient rat optic nerve. Brain Res Dev Brain Res 72(1):15\u201320. https:\/\/doi.org\/10.1016\/0165-3806(93)90155-4","journal-title":"Brain Res Dev Brain Res"},{"issue":"2","key":"4617_CR61","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1007\/s11481-016-9652-2","volume":"11","author":"T Buzhdygan","year":"2016","unstructured":"Buzhdygan T, Lisinicchia J, Patel V, Johnson K, Neugebauer V, Paessler S, Jennings K, Gelman B (2016) Neuropsychological, neurovirological and neuroimmune aspects of abnormal GABAergic transmission in HIV \u0131nfection. J Neuroimmune Pharmacol 11(2):279\u2013293. https:\/\/doi.org\/10.1007\/s11481-016-9652-2","journal-title":"J Neuroimmune Pharmacol"},{"key":"4617_CR62","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/j.jneuroim.2015.04.001","volume":"282","author":"RD Sanders","year":"2015","unstructured":"Sanders RD, Grover V, Goulding J, Godlee A, Gurney S, Snelgrove R, Ma D, Singh S, Maze M, Hussell T (2015) Immune cell expression of GABAA receptors and the effects of diazepam on influenza infection. J Neuroimmunol 282:97\u2013103. https:\/\/doi.org\/10.1016\/j.jneuroim.2015.04.001","journal-title":"J Neuroimmunol"},{"issue":"7","key":"4617_CR63","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1007\/s10096-011-1475-8","volume":"31","author":"M Sidorkiewicz","year":"2012","unstructured":"Sidorkiewicz M, Brocka M, Bronis M, Grek M, Jozwiak B, Piekarska A, Bartkowiak J (2012) The altered expression of alpha1 and beta3 subunits of the gamma-aminobutyric acid A receptor is related to the hepatitis C virus infection. Eur J Clin Microbiol \u0130nfect Dis 31(7):1537\u20131542. https:\/\/doi.org\/10.1007\/s10096-011-1475-8","journal-title":"Eur J Clin Microbiol \u0130nfect Dis"},{"issue":"3","key":"4617_CR64","doi-asserted-by":"publisher","first-page":"599","DOI":"10.1016\/j.mcn.2007.12.009","volume":"37","author":"V Magnaghi","year":"2008","unstructured":"Magnaghi V, Ballabio M, Camozzi F, Colleoni M, Consoli A, Gassmann M, Lauria G, Motta M, Procacci P, Trovato AE, Bettler B (2008) Altered peripheral myelination in mice lacking GABAB receptors. Mol Cell Neurosci 37(3):599\u2013609. https:\/\/doi.org\/10.1016\/j.mcn.2007.12.009","journal-title":"Mol Cell Neurosci"},{"issue":"2","key":"4617_CR65","doi-asserted-by":"publisher","first-page":"1461","DOI":"10.1007\/s12035-018-1158-x","volume":"56","author":"A Faroni","year":"2019","unstructured":"Faroni A, Melfi S, Castelnovo LF, Bonalume V, Colleoni D, Magni P, Arauzo-Bravo MJ, Reinbold R, Magnaghi V (2019) GABA-B1 receptor-null Schwann cells exhibit compromised \u0131n vitro myelination. Mol Neurobiol 56(2):1461\u20131474. https:\/\/doi.org\/10.1007\/s12035-018-1158-x","journal-title":"Mol Neurobiol"},{"issue":"4","key":"4617_CR66","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1002\/glia.22625","volume":"62","author":"A Faroni","year":"2014","unstructured":"Faroni A, Castelnovo LF, Procacci P, Caffino L, Fumagalli F, Melfi S, Gambarotta G, Bettler B, Wrabetz L, Magnaghi V (2014) Deletion of GABA-B receptor in Schwann cells regulates remak bundles and small nociceptive C-fibers. Glia 62(4):548\u2013565. https:\/\/doi.org\/10.1002\/glia.22625","journal-title":"Glia"},{"issue":"1","key":"4617_CR67","doi-asserted-by":"publisher","first-page":"47","DOI":"10.2174\/157015907780077132","volume":"5","author":"V Magnaghi","year":"2007","unstructured":"Magnaghi V (2007) GABA and neuroactive steroid interactions in glia: new roles for old players? Curr Neuropharmacol 5(1):47\u201364","journal-title":"Curr Neuropharmacol"},{"issue":"10","key":"4617_CR68","doi-asserted-by":"publisher","first-page":"2641","DOI":"10.1111\/j.0953-816X.2004.03368.x","volume":"19","author":"V Magnaghi","year":"2004","unstructured":"Magnaghi V, Ballabio M, Cavarretta IT, Froestl W, Lambert JJ, Zucchi I, Melcangi RC (2004) GABAB receptors in Schwann cells influence proliferation and myelin protein expression. Eur J Neurosci 19(10):2641\u20132649. https:\/\/doi.org\/10.1111\/j.0953-816X.2004.03368.x","journal-title":"Eur J Neurosci"},{"issue":"3","key":"4617_CR69","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.ejpain.2004.06.004","volume":"9","author":"TL Jones","year":"2005","unstructured":"Jones TL, Sweitzer SM, Peters MC, Wilson SP, Yeomans DC (2005) GABAB receptors on central terminals of C-afferents mediate intersegmental Adelta-afferent evoked hypoalgesia. Eur J Pain (London, England) 9(3):233\u2013242. https:\/\/doi.org\/10.1016\/j.ejpain.2004.06.004","journal-title":"Eur J Pain (London, England)"},{"issue":"2","key":"4617_CR70","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s00232-006-0877-5","volume":"213","author":"BI Kanner","year":"2006","unstructured":"Kanner BI (2006) Structure and function of sodium-coupled GABA and glutamate transporters. J Membr Biol 213(2):89\u2013100. https:\/\/doi.org\/10.1007\/s00232-006-0877-5","journal-title":"J Membr Biol"},{"issue":"3","key":"4617_CR71","doi-asserted-by":"crossref","first-page":"2106","DOI":"10.1016\/S0021-9258(18)53968-5","volume":"268","author":"QR Liu","year":"1993","unstructured":"Liu QR, Lopez-Corcuera B, Mandiyan S, Nelson H, Nelson N (1993) Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected]. The Biol Chem 268(3):2106\u20132112","journal-title":"The Biol Chem"},{"issue":"23","key":"4617_CR72","doi-asserted-by":"publisher","first-page":"10251","DOI":"10.1523\/JNEUROSCI.22-23-10251.2002","volume":"22","author":"CS Chiu","year":"2002","unstructured":"Chiu CS, Jensen K, Sokolova I, Wang D, Li M, Deshpande P, Davidson N, Mody I, Quick MW, Quake SR, Lester HA (2002) Number, density, and surface\/cytoplasmic distribution of GABA transporters at presynaptic structures of knock-in mice carrying GABA transporter subtype 1-green fluorescent protein fusions. J Neurosci 22(23):10251\u201310266","journal-title":"J Neurosci"},{"issue":"4974","key":"4617_CR73","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1126\/science.1975955","volume":"249","author":"J Guastella","year":"1990","unstructured":"Guastella J, Nelson N, Nelson H, Czyzyk L, Keynan S, Miedel MC, Davidson N, Lester HA, Kanner BI (1990) Cloning and expression of a rat brain GABA transporter. Science (New York, NY) 249(4974):1303\u20131306. https:\/\/doi.org\/10.1126\/science.1975955","journal-title":"Science (New York, NY)"},{"issue":"3","key":"4617_CR74","doi-asserted-by":"publisher","first-page":"2073","DOI":"10.1152\/jn.00520.2005","volume":"94","author":"S Keros","year":"2005","unstructured":"Keros S, Hablitz JJ (2005) Subtype-specific GABA transporter antagonists synergistically modulate phasic and tonic GABAA conductances in rat neocortex. J Neurophysiol 94(3):2073\u20132085. https:\/\/doi.org\/10.1152\/jn.00520.2005","journal-title":"J Neurophysiol"}],"container-title":["Archives of Virology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-020-04617-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00705-020-04617-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-020-04617-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,5]],"date-time":"2021-04-05T23:43:04Z","timestamp":1617666184000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00705-020-04617-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,6]]},"references-count":74,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["4617"],"URL":"https:\/\/doi.org\/10.1007\/s00705-020-04617-3","relation":{},"ISSN":["0304-8608","1432-8798"],"issn-type":[{"value":"0304-8608","type":"print"},{"value":"1432-8798","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,6]]},"assertion":[{"value":"2 January 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 March 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 April 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}