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The available epidemiological data on parvovirus infection in cats in Egypt is limited. Therefore, the aim of the current study was to provide data concerning the epidemiological profile of cats infected with parvovirus, including the prevalence of parvovirus infection in cats in three Egyptian provinces (Sohag, Assiut, and Cairo) and the associated risk factors. Using rapid antigen tests of fecal samples and conventional PCR, the overall prevalence of parvovirus infection in cats was found to be 35% (35\/100) and 43% (43\/100), respectively. Anorexia, bloody diarrhea, severe dehydration, hypothermia, and vomiting were the most common clinical findings significantly associated with parvovirus-infected cats. The geographical location (Sohag) and the season (winter) were both statistically significant risk factors for parvovirus infection. These findings indicate that parvoviruses are circulating in different regions of Egypt. Our study provides baseline epidemiological data for future preventive and control measures against parvovirus infection, as well as highlighting the need for future genomic surveillance studies involving a large study population from various parts of Egypt in order to better shape the epidemiological picture of parvovirus infection.<\/jats:p>","DOI":"10.1007\/s00705-023-05751-4","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T23:42:51Z","timestamp":1680133371000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Clinico-epidemiological survey of feline parvovirus circulating in three Egyptian provinces from 2020 to 2021"],"prefix":"10.1007","volume":"168","author":[{"given":"Mohamed M.M.","family":"Abdel-Baky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled A.S.","family":"El-Khabaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelbaset E.","family":"Abdelbaset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6020-6540","authenticated-orcid":false,"given":"Maha I.","family":"Hamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"key":"5751_CR1","doi-asserted-by":"publisher","first-page":"667","DOI":"10.7589\/0090-3558-42.3.667","volume":"42","author":"M Driciru","year":"2006","unstructured":"Driciru M, Siefert L, Prager KC et al (2006) A serosurvey of viral infections in lions (Panthera leo), from Queen Elizabeth National Park, Uganda. 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