{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T03:15:09Z","timestamp":1792984509035,"version":"4.5.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,3,21]],"date-time":"2025-03-21T00:00:00Z","timestamp":1742515200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Virol"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1007\/s00705-025-06270-0","type":"journal-article","created":{"date-parts":[[2025,3,22]],"date-time":"2025-03-22T23:29:20Z","timestamp":1742686160000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["The resurgence of monkeypox clade Ib: a global health emergency and concern"],"prefix":"10.1007","volume":"170","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5682-0938","authenticated-orcid":false,"given":"Suresh","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunasekaran","family":"Subramaniam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. J.","family":"Senthil Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,3,21]]},"reference":[{"key":"6270_CR1","doi-asserted-by":"publisher","first-page":"S146","DOI":"10.1093\/ofid\/ofae503","volume":"11","author":"K Abdullah","year":"2024","unstructured":"Abdullah K et al (2024) A review of evidence related to the zoonotic characteristics of the Monkeypox Virus. Open Forum Infect Dis 11:S146-s155. https:\/\/doi.org\/10.1093\/ofid\/ofae503","journal-title":"Open Forum Infect Dis"},{"key":"6270_CR2","doi-asserted-by":"publisher","first-page":"1360586","DOI":"10.3389\/fcimb.2024.1360586","volume":"14","author":"E Alakunle","year":"2024","unstructured":"Alakunle E et al (2024) A comprehensive review of monkeypox virus and mpox characteristics. Front Cell Infect Microbiol 14:1360586. https:\/\/doi.org\/10.3389\/fcimb.2024.1360586","journal-title":"Front Cell Infect Microbiol"},{"key":"6270_CR3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2220415120","volume":"120","author":"JL Americo","year":"2023","unstructured":"Americo JL, Earl PL, Moss B (2023) Virulence differences of mpox (monkeypox) virus clades I, IIa, and IIb.1 in a small animal model. Proc Natl Acad Sci U S A 120:e222. https:\/\/doi.org\/10.1073\/pnas.2220415120","journal-title":"Proc Natl Acad Sci U S A"},{"key":"6270_CR4","doi-asserted-by":"publisher","first-page":"269","DOI":"10.53854\/liim-3103-1","volume":"31","author":"S Antinori","year":"2023","unstructured":"Antinori S, Casalini G, Giacomelli A, Rodriguez-Morales AJ (2023) Update on Mpox: a brief narrative review. Infez Med 31:269\u2013276. https:\/\/doi.org\/10.53854\/liim-3103-1","journal-title":"Infez Med"},{"key":"6270_CR5","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.3390\/jcm13082234","volume":"13","author":"F Branda","year":"2024","unstructured":"Branda F et al (2024) Mpox: an overview of pathogenesis, diagnosis, and public health implications. J Clin Med 13:2234","journal-title":"J Clin Med"},{"key":"6270_CR6","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.2508","volume":"34","author":"W Cho","year":"2024","unstructured":"Cho W et al (2024) Clinical characteristics and outcomes of patients with mpox during the 2022 mpox outbreak compared with those before the outbreak: a systematic review and meta-analysis. Rev Med Virol 34:e2508. https:\/\/doi.org\/10.1002\/rmv.2508","journal-title":"Rev Med Virol"},{"key":"6270_CR7","unstructured":"Control ECfDPa (2024) Communicable disease threats report: 24\u201330 August 2024, week 35. In, Solna, Sweden"},{"key":"6270_CR8","unstructured":"Diseases NIfC (2024) Mpox outbreak alert: Africa\u2019s crisis and south Africa\u2019s response. In. National Institute for Communicable Diseases, South Africa"},{"key":"6270_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.microb.2024.100141","volume":"4","author":"PM Duarte","year":"2024","unstructured":"Duarte PM et al (2024) Unveiling the global surge of Mpox (Monkeypox): a comprehensive review of current evidence. Microbe 4:100141. https:\/\/doi.org\/10.1016\/j.microb.2024.100141","journal-title":"Microbe"},{"key":"6270_CR10","doi-asserted-by":"publisher","first-page":"9527","DOI":"10.1128\/jvi.00199-11","volume":"85","author":"RD Estep","year":"2011","unstructured":"Estep RD et al (2011) Deletion of the monkeypox virus inhibitor of complement enzymes locus impacts the adaptive immune response to monkeypox virus in a nonhuman primate model of infection. J Virol 85:9527\u20139542. https:\/\/doi.org\/10.1128\/jvi.00199-11","journal-title":"J Virol"},{"key":"6270_CR11","doi-asserted-by":"crossref","first-page":"2190","DOI":"10.3390\/ani12172190","volume":"12","author":"E Gomez-Lucia","year":"2022","unstructured":"Gomez-Lucia E (2022) Monkeypox: some keys to understand this emerging disease. Animals 12:2190","journal-title":"Animals"},{"key":"6270_CR12","doi-asserted-by":"publisher","first-page":"2600","DOI":"10.1080\/22221751.2022.2132882","volume":"11","author":"MM Hatmal","year":"2022","unstructured":"Hatmal MM et al (2022) Comprehensive literature review of monkeypox. Emerg Microbes Infect 11:2600\u20132631. https:\/\/doi.org\/10.1080\/22221751.2022.2132882","journal-title":"Emerg Microbes Infect"},{"key":"6270_CR13","doi-asserted-by":"publisher","first-page":"6778","DOI":"10.1038\/s41467-024-51074-6","volume":"15","author":"Y Huang","year":"2024","unstructured":"Huang Y et al (2024) Multiomics characterization of the monkeypox virus infection. Nat Commun 15:6778. https:\/\/doi.org\/10.1038\/s41467-024-51074-6","journal-title":"Nat Commun"},{"key":"6270_CR14","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.2522","volume":"34","author":"W Jiang","year":"2024","unstructured":"Jiang W et al (2024) Breakthrough infection and reinfection in patients with mpox. Rev Med Virol 34:e2522. https:\/\/doi.org\/10.1002\/rmv.2522","journal-title":"Rev Med Virol"},{"key":"6270_CR15","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1016\/j.jiph.2023.02.003","volume":"16","author":"A Karagoz","year":"2023","unstructured":"Karagoz A et al (2023) Monkeypox (mpox) virus: Classification, origin, transmission, genome organization, antiviral drugs, and molecular diagnosis. J Infect Publ Health 16:531\u2013541. https:\/\/doi.org\/10.1016\/j.jiph.2023.02.003","journal-title":"J Infect Publ Health"},{"key":"6270_CR16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgph.0002731","volume":"4","author":"R Kuehn","year":"2024","unstructured":"Kuehn R, Fox T, Guyatt G, Lutje V, Gould S (2024) Infection prevention and control measures to reduce the transmission of mpox: a systematic review. PLOS Glob Public Health 4:e0002731. https:\/\/doi.org\/10.1371\/journal.pgph.0002731","journal-title":"PLOS Glob Public Health"},{"key":"6270_CR17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/pathogens14010001","volume":"14","author":"S Kumar","year":"2025","unstructured":"Kumar S, Guruparan D, Karuppanan K, Kumar KJS (2025) Comprehensive insights into Monkeypox (mpox): recent advances in epidemiology, diagnostic approaches and therapeutic strategies. Pathogens 14:1","journal-title":"Pathogens"},{"key":"6270_CR18","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.27894","volume":"95","author":"S Kumar","year":"2023","unstructured":"Kumar S, Subramaniam G, Karuppanan K (2023) Human monkeypox outbreak in 2022. J Med Virol 95:e27894. https:\/\/doi.org\/10.1002\/jmv.27894","journal-title":"J Med Virol"},{"key":"6270_CR19","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/978-3-319-22246-2_24","volume-title":"Problematic wildlife: a cross-disciplinary approach","author":"LA Kurpiers","year":"2016","unstructured":"Kurpiers LA, Schulte-Herbr\u00fcggen B, Ejotre I, Reeder DM (2016) Bushmeat and emerging infectious diseases: lessons from Africa. In: Angelici FM (ed) Problematic wildlife: a cross-disciplinary approach. Springer International Publishing, Cham, pp 507\u2013551"},{"key":"6270_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.10.017","author":"E Lusamaki","year":"2024","unstructured":"Lusamaki E et al (2024) Clade I mpox virus genomic diversity in the Democratic Republic of the Congo, 2018\u20132024: predominance of zoonotic transmission. Cell. https:\/\/doi.org\/10.1016\/j.cell.2024.10.017","journal-title":"Cell"},{"key":"6270_CR21","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.67872","volume":"16","author":"S Mani","year":"2024","unstructured":"Mani S et al (2024) Epidemiology, virology, and mutation landscape of monkeypox virus from past to present. Cureus 16:e67872. https:\/\/doi.org\/10.7759\/cureus.67872","journal-title":"Cureus"},{"key":"6270_CR22","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3390\/pathogens12070947","volume":"12","author":"DE Mart\u00ednez-Fern\u00e1ndez","year":"2023","unstructured":"Mart\u00ednez-Fern\u00e1ndez DE et al (2023) Human monkeypox: a comprehensive overview of epidemiology, pathogenesis, diagnosis, treatment, and prevention strategies. Pathogens 12:8. https:\/\/doi.org\/10.3390\/pathogens12070947","journal-title":"Pathogens"},{"key":"6270_CR23","doi-asserted-by":"publisher","first-page":"3059","DOI":"10.1038\/s41467-024-46949-7","volume":"15","author":"S Monz\u00f3n","year":"2024","unstructured":"Monz\u00f3n S et al (2024) Monkeypox virus genomic accordion strategies. Nat Commun 15:3059. https:\/\/doi.org\/10.1038\/s41467-024-46949-7","journal-title":"Nat Commun"},{"key":"6270_CR24","doi-asserted-by":"publisher","DOI":"10.1016\/j.soh.2024.100085","volume":"3","author":"DB Olawade","year":"2024","unstructured":"Olawade DB et al (2024) Strengthening Africa\u2019s response to Mpox (monkeypox): insights from historical outbreaks and the present global spread. Sci One Health 3:100085. https:\/\/doi.org\/10.1016\/j.soh.2024.100085","journal-title":"Sci One Health"},{"key":"6270_CR25","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgast-2023-001266","volume":"11","author":"R Ramakrishnan","year":"2024","unstructured":"Ramakrishnan R, Shenoy A, Madhavan R, Meyer D (2024) Mpox gastrointestinal manifestations: a systematic review. BMJ Open Gastroenterol 11:e001266. https:\/\/doi.org\/10.1136\/bmjgast-2023-001266","journal-title":"BMJ Open Gastroenterol"},{"key":"6270_CR26","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.3390\/microorganisms12091874","volume":"12","author":"F Scarpa","year":"2024","unstructured":"Scarpa F et al (2024) Update of the genetic variability of monkeypox virus clade IIb lineage B1. Microorganisms 12:1874","journal-title":"Microorganisms"},{"key":"6270_CR27","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.3390\/v16071123","volume":"16","author":"DA Schwartz","year":"2024","unstructured":"Schwartz DA (2024) High rates of miscarriage and stillbirth among pregnant women with clade I Mpox (Monkeypox) are confirmed during 2023\u20132024 DR Congo outbreak in South Kivu Province. Viruses 16:1123","journal-title":"Viruses"},{"key":"6270_CR28","doi-asserted-by":"publisher","DOI":"10.3390\/v15081649","author":"DA Schwartz","year":"2023","unstructured":"Schwartz DA, Pittman PR (2023) Mpox (Monkeypox) in pregnancy: viral clade differences and their associations with varying obstetrical and fetal outcomes. Viruses. https:\/\/doi.org\/10.3390\/v15081649","journal-title":"Viruses"},{"key":"6270_CR29","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1504154","author":"S Srivastava","year":"2024","unstructured":"Srivastava S et al (2024) Clade Ib: a new emerging threat in the Mpox outbreak. Front Pharmacol. https:\/\/doi.org\/10.3389\/fphar.2024.1504154","journal-title":"Front Pharmacol"},{"key":"6270_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(23)00055-5","author":"D Ulaeto","year":"2023","unstructured":"Ulaeto D et al (2023) New nomenclature for mpox (monkeypox) and monkeypox virus clades. Lancet Infect Dis. https:\/\/doi.org\/10.1016\/S1473-3099(23)00055-5","journal-title":"Lancet Infect Dis"},{"key":"6270_CR31","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-024-03130-3","author":"EH Vakaniaki","year":"2024","unstructured":"Vakaniaki EH et al (2024) Sustained human outbreak of a new MPXV clade I lineage in eastern Democratic Republic of the Congo. Nat Med. https:\/\/doi.org\/10.1038\/s41591-024-03130-3","journal-title":"Nat Med"},{"key":"6270_CR32","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1111\/j.1600-065X.2008.00691.x","volume":"225","author":"JR Weaver","year":"2008","unstructured":"Weaver JR, Isaacs SN (2008) Monkeypox virus and insights into its immunomodulatory proteins. Immunol Rev 225:96\u2013113. https:\/\/doi.org\/10.1111\/j.1600-065X.2008.00691.x","journal-title":"Immunol Rev"},{"key":"6270_CR33","doi-asserted-by":"publisher","first-page":"e121","DOI":"10.1093\/infdis\/jiad414","volume":"230","author":"M Xiridou","year":"2023","unstructured":"Xiridou M, Miura F, Adam P, Op de Coul E, de Wit J, Wallinga J (2023) The fading of the mpox outbreak among men who have sex with men: a mathematical modelling study. J Infect Dis 230:e121\u2013e130. https:\/\/doi.org\/10.1093\/infdis\/jiad414","journal-title":"J Infect Dis"},{"key":"6270_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellin.2024.100185","volume":"3","author":"XM Yi","year":"2024","unstructured":"Yi XM, Lei YL, Li M, Zhong L, Li S (2024) The monkeypox virus-host interplays. Cell Insight 3:100185. https:\/\/doi.org\/10.1016\/j.cellin.2024.100185","journal-title":"Cell Insight"},{"key":"6270_CR35","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1186\/s12863-023-01171-0","volume":"24","author":"J Zhu","year":"2023","unstructured":"Zhu J et al (2023) Exploring the key genomic variation in monkeypox virus during the 2022 outbreak. BMC Genom Data 24:67. https:\/\/doi.org\/10.1186\/s12863-023-01171-0","journal-title":"BMC Genom Data"}],"container-title":["Archives of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-025-06270-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00705-025-06270-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-025-06270-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T20:36:33Z","timestamp":1743366993000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00705-025-06270-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,21]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["6270"],"URL":"https:\/\/doi.org\/10.1007\/s00705-025-06270-0","relation":{},"ISSN":["0304-8608","1432-8798"],"issn-type":[{"value":"0304-8608","type":"print"},{"value":"1432-8798","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,21]]},"assertion":[{"value":"20 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 January 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"84"}}