{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T15:20:53Z","timestamp":1783524053084,"version":"3.55.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100009594","name":"University of P\u00e9cs","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009594","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Virol"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In this study, the presence of a betacoronavirus (species\n                    <jats:italic>Betacoronavirus erinacei<\/jats:italic>\n                    , genus\n                    <jats:italic>Betacoronavirus<\/jats:italic>\n                    , family\n                    <jats:italic>Coronaviridae<\/jats:italic>\n                    ) was investigated in faecal samples collected from northern white-breasted hedgehogs (\n                    <jats:italic>Erinaceus roumanicus<\/jats:italic>\n                    ) in different sampling areas in Hungary using reverse transcription PCR (RT-PCR) and sequencing methods. A total of 23 (27.4%) of the 84 specimens were positive for betacoronaviruses (PX460030-PX460052), and the region of the viral genome encoding the complete spike protein was sequenced for eight of the positive samples. The complete spike genes from these eight specimens showed 91\u201394% nucleotide (nt) and 92\u201394% amino acid (aa) sequence identity to each other and 86\u201391% nt and 87\u201392% aa sequence identity to the other European hedgehog coronavirus strains. Hedgehog betacoronavirus is a common and widespread infectious agent in the three hedgehog species (\n                    <jats:italic>E. europaeus, E. amurensis<\/jats:italic>\n                    , and, based on this study,\n                    <jats:italic>E. roumanicus<\/jats:italic>\n                    ) studied in Europe and Asia so far, with geographical and probably host-species-specific genetic lineages.\n                  <\/jats:p>","DOI":"10.1007\/s00705-025-06506-z","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T16:28:55Z","timestamp":1767803335000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Detection and molecular analysis of betacoronaviruses (family Coronaviridae) in hedgehogs (Erinaceus roumanicus) in Hungary"],"prefix":"10.1007","volume":"171","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5857-4934","authenticated-orcid":false,"given":"G\u00e1bor","family":"Reuter","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara Ester","family":"Cora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e1roly","family":"Tak\u00e1ts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1kos","family":"Boros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f3bert","family":"M\u00e1tics","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benigna","family":"Bal\u00e1zs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9419-2522","authenticated-orcid":false,"given":"P\u00e9ter","family":"Pankovics","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"6506_CR1","doi-asserted-by":"publisher","first-page":"100940","DOI":"10.1016\/j.onehlt.2024.100940","volume":"19","author":"AVS Cruz","year":"2024","unstructured":"Cruz AVS, Santos-Silva S, Queir\u00f3s-Reis L, Rodrigues C, Soeiro V, Tarlinton RE, Mesquita JR (2024) Genomic characterization and cross-species transmission potential of hedgehog coronavirus. One Health 19:100940","journal-title":"One Health"},{"key":"6506_CR2","doi-asserted-by":"publisher","first-page":"717","DOI":"10.1128\/JVI.01600-13","volume":"88","author":"VM Corman","year":"2014","unstructured":"Corman VM, Kollies R, Phillipps H, G\u00f6pner G, M\u00fcller MA, Eckerle I, Br\u00fcnink S, Drosten C, Drexler JF (2014) Characterization of a novel betecoronavirus related to Middle East respiratory syndrome coronavirus in European hedgehogs. J Virol 88:717\u2013724","journal-title":"J Virol"},{"key":"6506_CR3","doi-asserted-by":"publisher","first-page":"e169","DOI":"10.1017\/S0950268819000207","volume":"147","author":"IF Saldanha","year":"2019","unstructured":"Saldanha IF, Lawson B, Goharriz H, Rodriguez-Ramos Fernandez J, John SK, Fooks AR, Cunningham AA, Johnson N, Horton DL (2019) Extension of the known distribution of a novel clade C betacoronavirus in wildlife host. Epidemiol Infect 147:e169","journal-title":"Epidemiol Infect"},{"key":"6506_CR4","doi-asserted-by":"publisher","first-page":"1213990","DOI":"10.3389\/fvets.2023.1213990","volume":"10","author":"L De Sabato","year":"2023","unstructured":"De Sabato L, Laniro G, Manzia F, Monini M, Chiappini B, Di Bartolo I, Vaccari G (2023) Erinaceus coronavirus persistence in hedgehogs (Erinaceus europaeus) in a non-invasive, in vivo, experimental setting. Front Vet Sci 10:1213990","journal-title":"Front Vet Sci"},{"key":"6506_CR5","doi-asserted-by":"publisher","first-page":"2386","DOI":"10.1038\/s41598-022-06432-z","volume":"12","author":"M Pomorska-M\u00f3l","year":"2022","unstructured":"Pomorska-M\u00f3l M, Ruszkowski JJ, Gogulski M, Domanska-Blicharz K (2022) First detection of hedgehog coronavirus 1 in Poland. Sci Rep 12:2386","journal-title":"Sci Rep"},{"key":"6506_CR6","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1186\/s12917-024-04277-4","volume":"20","author":"K Domanska-Blicharz","year":"2024","unstructured":"Domanska-Blicharz K, Lisowska A, Opolska J, Ruszkowski JJ, Gogulski M, Pomorska-M\u00f3l M (2024) Whole genome characteristics of hedgehog coronaviruses from Poland and analysis of the evolution of the spike protein for its interspecies transmission potential. BMC Vet Res 20:424","journal-title":"BMC Vet Res"},{"key":"6506_CR7","doi-asserted-by":"publisher","first-page":"e0015725","DOI":"10.1128\/mra.00157-25","volume":"9","author":"K Beissat","year":"2025","unstructured":"Beissat K, Picard-Mexer E, Arn\u00e9 P, Chanteclair F, Le Berzic C, Hivert L, Le Loc\u2019h G, Puech MP, Bastien F, Schereffer JL, Wasniewski M (2025) Coding-complete genome sequences of hedgehog coronavirus isolated from Erinaceus europaeus in France. Microbiol Resour Announc 9:e0015725","journal-title":"Microbiol Resour Announc"},{"issue":"11","key":"6506_CR8","doi-asserted-by":"publisher","first-page":"980","DOI":"10.3390\/v11110980","volume":"11","author":"AKP Lau","year":"2019","unstructured":"Lau AKP, Luk HKH, Wong ACP, Fan RYY, Lam CSF, Li KSM, Ahmed SS, Chow FWN, Cai JP, Zhu X, Chan JFW, Lau TCK, Cao K, Li M, Woo PCY, Yuen KY (2019) Identification of a novel betacoronavirus (Merbecovirus) in Amur hedgehogs from China. Viruses 11(11):980","journal-title":"Viruses"},{"key":"6506_CR9","doi-asserted-by":"publisher","first-page":"100332","DOI":"10.1016\/j.onehlt.2021.100332","volume":"13","author":"D Li","year":"2021","unstructured":"Li D, Gong XQ, Xiao X, Han HJ, Yu H, Li ZM, Yan LN, Gu XI, Duan SH, JieYu X (2021) MERS-related CoVs in hedgehogs from Hubei province, China. 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