{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T13:54:13Z","timestamp":1774965253007,"version":"3.50.1"},"reference-count":76,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Virol"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1007\/s00705-026-06556-x","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T06:53:34Z","timestamp":1772175214000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Prophylactic and Immunomodulatory potential of gooseberry (Phyllanthus acidus) and oregano (Coleus amboinicus) extracts against tilapia lake virus (TiLV) in tilapia"],"prefix":"10.1007","volume":"171","author":[{"given":"Sekar","family":"Gobinath","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1056-6513","authenticated-orcid":false,"given":"Bagthasingh","family":"Chrisolite","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panchavarnam","family":"Sivasankar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. Senthil","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anix Vivek","family":"Santhiya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Palaniappan","family":"Subash","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Mohamed","family":"Mansoor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muthumariappan","family":"Selvamagheswaran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulraj Magesh","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"6556_CR1","volume-title":"The state of world fisheries and aquaculture 2022. Towards blue transformation, the state of world fisheries and aquaculture (SOFIA)","author":"FAO","year":"2022","unstructured":"FAO (2022) The state of world fisheries and aquaculture 2022. Towards blue transformation, the state of world fisheries and aquaculture (SOFIA). Food and Agriculture Organization of the United Nations, Rome, Italy"},{"key":"6556_CR2","doi-asserted-by":"publisher","first-page":"1115","DOI":"10.1111\/jfd.13237","volume":"43","author":"W Surachetpong","year":"2020","unstructured":"Surachetpong W, Roy SRK, Nicholson P (2020) Tilapia lake virus: the story so Far. J Fish Dis 43:1115\u20131132","journal-title":"J Fish Dis"},{"key":"6556_CR3","doi-asserted-by":"publisher","first-page":"4137","DOI":"10.1128\/JCM.00827-14","volume":"52","author":"M Eyngor","year":"2014","unstructured":"Eyngor M, Zamostiano R, Kembou Tsofack JE, Berkowitz A, Bercovier H, Tinman S, Eldar A (2014) Identification of a novel RNA virus lethal to tilapia. J Clin Microbiol 52:4137\u20134146","journal-title":"J Clin Microbiol"},{"key":"6556_CR4","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1111\/jfd.12142","volume":"37","author":"HW Ferguson","year":"2014","unstructured":"Ferguson HW, Kabuusu R, Beltran S, Reyes E, Lince JA, del Pozo J (2014) Syncytial hepatitis of farmed tilapia, Oreochromis niloticus (L.): a case report. J Fish Dis 37:583\u2013589","journal-title":"J Fish Dis"},{"key":"6556_CR5","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1128\/JCM.01808-16","volume":"55","author":"JEK Tsofack","year":"2017","unstructured":"Tsofack JEK, Zamostiano R, Watted S, Berkowitz A, Rosenbluth E, Mishra N, Briese T, Lipkin WI, Kabuusu RM, Ferguson H, Del Pozo J (2017) Detection of tilapia lake virus in clinical samples by culturing and nested reverse transcription-PCR. J Clin Microbiol 55:759\u2013767","journal-title":"J Clin Microbiol"},{"key":"6556_CR6","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1016\/j.aquaculture.2017.03.014","volume":"473","author":"M Fathi","year":"2017","unstructured":"Fathi M, Dickson C, Dickson M, Leschen W, Baily J, Muir F, Ulrich K, Weidmann M (2017) Identification of tilapia lake virus in Egypt in nile tilapia affected by \u2018summer mortality\u2019 syndrome. Aquaculture 473:430\u2013432","journal-title":"Aquaculture"},{"key":"6556_CR7","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.3201\/eid2306.161278","volume":"23","author":"W Surachetpong","year":"2017","unstructured":"Surachetpong W, Janetanakit T, Nonthabenjawan N, Tattiyapong P, Sirikanchana K, Amonsin A (2017) Outbreaks of tilapia lake virus infection, Thailand, 2015\u20132016. Emerg Infect Dis 23:1031\u20131033","journal-title":"Emerg Infect Dis"},{"key":"6556_CR8","unstructured":"OIE (2017b) Immediate notifications and follow-ups. Tilapia lake virus, Chinese Taipei"},{"key":"6556_CR9","doi-asserted-by":"crossref","unstructured":"Behera BK, Pradhan PK, Swaminathan TR, Sood N, Paria P, Das A, Verma DK, Kumar R, Yadav MK, Dev AK (2018) Emergence of tilapia lake virus associated with mortalities of farmed Nile tilapia Oreochromis niloticus (Linnaeus 1758) in India. Aquaculture 484:168\u2013174","DOI":"10.1016\/j.aquaculture.2017.11.025"},{"key":"6556_CR10","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.aquaculture.2017.11.019","volume":"485","author":"MNA Amal","year":"2018","unstructured":"Amal MNA, Koh CB, Nurliyana M, Suhaiba M, Nor-Amalina Z, Santha S, Zamri-Saad M (2018) A case of natural co-infection of tilapia lake virus and Aeromonas veronii in a Malaysian red hybrid tilapia (Oreochromis niloticus \u00d7 O. mossambicus) farm experiencing high mortality. Aquaculture 485:12\u201316","journal-title":"Aquaculture"},{"key":"6556_CR11","doi-asserted-by":"publisher","first-page":"1381","DOI":"10.1111\/jfd.13235","volume":"43","author":"PP Debnath","year":"2020","unstructured":"Debnath PP, Delamare-Deboutteville J, Jansen MD, Phiwsaiya K, Dalia A, Hasan MA, Senapin S, Mohan CV, Dong HT, Rodkhum C (2020) Two-year surveillance of tilapia lake virus (TiLV) reveals its wide circulation in tilapia farms and hatcheries from multiple districts of Bangladesh. J Fish Dis 43:1381\u20131389","journal-title":"J Fish Dis"},{"key":"6556_CR12","doi-asserted-by":"publisher","first-page":"1181","DOI":"10.1111\/jfd.12790","volume":"41","author":"KK Mugimba","year":"2018","unstructured":"Mugimba KK, Chengula AA, Wamala S, Mwega ED, Kasanga CJ, Byarugaba DK, Mdegela RH, Tal S, Bornstein B, Dishon A (2018) Detection of tilapia lake virus (TiLV) infection by PCR in farmed and wild nile tilapia (Oreochromis niloticus) from lake Victoria. J Fish Dis 41:1181\u20131189","journal-title":"J Fish Dis"},{"key":"6556_CR13","unstructured":"OIE (2018c) Immediate notification. Tilapia lake virus, Peru"},{"key":"6556_CR14","unstructured":"OIE (2018b) Immediate notification. Tilapia lake virus, Mexico"},{"key":"6556_CR15","unstructured":"OIE (2017a) Immediate notifications and follow-ups. Tilapia lake virus, the Philippines"},{"key":"6556_CR16","doi-asserted-by":"publisher","first-page":"85","DOI":"10.15578\/jra.13.1.2018.85-92","volume":"13","author":"I Koesharyani","year":"2018","unstructured":"Koesharyani I, Gardenia L, Widowati Z, Khumaira K, Rustianti D (2018) Studi Kasus Infeksi tilapia lake virus (TiLV) Pada Ikan Nila (Oreochromis niloticus). J Ris Akuakultur 13:85\u201392","journal-title":"J Ris Akuakultur"},{"key":"6556_CR17","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1128\/MRA.01368-19","volume":"9","author":"MS Ahasan","year":"2020","unstructured":"Ahasan MS, Keleher W, Giray C, Perry B, Surachetpong W, Nicholson P, Al-Hussinee L, Subramaniam K, Waltzek TB (2020) Genomic characterization of tilapia lake virus isolates recovered from moribund nile tilapia (Oreochromis niloticus) on a farm in the united States. Microbiol Resour Announc 9:10\u2013128","journal-title":"Microbiol Resour Announc"},{"key":"6556_CR18","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.aaf.2021.04.007","volume":"7","author":"N Aich","year":"2022","unstructured":"Aich N, Paul A, Choudhury TG, Saha H (2022) Tilapia lake virus (TiLV) disease: current status of Understanding. Aquac Fish 7:7\u201317","journal-title":"Aquac Fish"},{"key":"6556_CR19","doi-asserted-by":"publisher","first-page":"2097","DOI":"10.1111\/jfd.13523","volume":"44","author":"TT Mai","year":"2021","unstructured":"Mai TT, Kayansamruaj P, Taengphu S, Senapin S, Costa JZ, del-Pozo J, Thompson KD, Rodkhum C, Dong HT (2021) Efficacy of heat-killed and formalin-killed vaccines against tilapia tilapinevirus in juvenile nile tilapia (Oreochromis niloticus). J Fish Dis 44:2097\u20132109","journal-title":"J Fish Dis"},{"key":"6556_CR20","doi-asserted-by":"publisher","first-page":"86","DOI":"10.3390\/vaccines9020086","volume":"9","author":"W Zeng","year":"2021","unstructured":"Zeng W, Wang Y, Hu H, Wang Q, Bergmann SM, Wang Y, Li BO, Lv Y, Li H, Yin J (2021) Cell culture-derived tilapia lake virus-inactivated vaccine containing Montanide adjuvant provides high protection against viral challenge for tilapia. Vaccines 9:86","journal-title":"Vaccines"},{"key":"6556_CR21","doi-asserted-by":"publisher","first-page":"101166","DOI":"10.1016\/j.aqrep.2022.101166","volume":"24","author":"N Yu","year":"2022","unstructured":"Yu N, Zeng W, Xiong Z, Liu Z (2022) A high efficacy DNA vaccine against tilapia lake virus in nile tilapia (Oreochromis niloticus). Aquac Rep 24:101166","journal-title":"Aquac Rep"},{"key":"6556_CR22","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1111\/j.1365-2761.2009.01100.x","volume":"32","author":"EJ Nya","year":"2009","unstructured":"Nya EJ, Austin B (2009) Use of Garlic (Allium sativum) to control Aeromonas hydrophila infection in rainbow trout (Oncorhynchus Mykiss (Walbaum)). J Fish Dis 32:963\u2013970","journal-title":"J Fish Dis"},{"key":"6556_CR23","doi-asserted-by":"publisher","first-page":"469","DOI":"10.3390\/antibiotics11040469","volume":"11","author":"MN Nik","year":"2022","unstructured":"Nik MN, Rahimi N, Natrah I, Loh JY, Ervin Ranzil FK, Gina M, Lim SHE, Chong CM (2022) Phytocompounds as an alternative antimicrobial approach in aquaculture. Antibiotics 11:469","journal-title":"Antibiotics"},{"key":"6556_CR24","unstructured":"Direkbusarakom S, Herunsalee A, Boonyaratpalin S, Danayadol Y, Aekpanithanpong (1993) The virucidal activity of Clinacanthus nutans (Lindau) against yellow head baculovirus of black tiger Prawn (Penaeus monodon), vol 8. National Institute of Coastal Aquaculture Technical paper No, p 7"},{"key":"6556_CR25","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13065-018-0412-7","volume":"12","author":"C Sowmya","year":"2018","unstructured":"Sowmya C, Lavakumar V, Venkateshan N, Ravichandiran V, Saigopal DVR (2018) Exploration of Phyllanthus acidus mediated silver nanoparticles and their activity against infectious bacterial pathogens. Chem Cent J 12:1\u20139","journal-title":"Chem Cent J"},{"key":"6556_CR26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2020\/3827912","volume":"2020","author":"K Wang","year":"2020","unstructured":"Wang K, Pan S, Qi Z, Xia P, Xu H, Kong W, Li H, Xue P, Yang X, Fu C (2020) Recent advances in chitosan-based metal nanocomposites for wound healing applications. Adv Mater Sci Eng 2020:1\u201313","journal-title":"Adv Mater Sci Eng"},{"key":"6556_CR27","unstructured":"Praveena B, Pradeep SN (2012) Antioxidant and antibacterial activities in the leaf extracts of Indian borage (Plectranthus amboinicus). Food Nutr Sci 3(2)"},{"key":"6556_CR28","doi-asserted-by":"crossref","unstructured":"J\u00f8rgensen JB (2014) The innate immune response in fish. Fish Vaccination, 85\u2013103","DOI":"10.1002\/9781118806913.ch8"},{"issue":"3","key":"6556_CR29","doi-asserted-by":"publisher","first-page":"361","DOI":"10.22159\/ajpcr.2018.v11i3.22614","volume":"11","author":"S Chigurupati","year":"2018","unstructured":"Chigurupati S, Kwang Yiik EW, Islam Mohammad J, Vijayabalan S, Krishnan Selvarajan K, Ramana Reddy MV, Sekhar Nanda S (2018) Screening antimicrobial potential for Malaysian originated Tamarindus indica ethanolic leaves extract. Asian J Pharm Clin Res 11(3):361\u2013363","journal-title":"Asian J Pharm Clin Res"},{"key":"6556_CR30","first-page":"171","volume":"4","author":"MA Mir","year":"2016","unstructured":"Mir MA, Parihar K, Tabasum U, Kumari EJJMPS (2016) Estimation of alkaloid, saponin and flavonoid content in various extracts of Crocus sativa. J Med Plants Stud 4:171\u2013174","journal-title":"J Med Plants Stud"},{"key":"6556_CR31","unstructured":"Batara DCR (2016) Cytotoxic effect and antioxidant activity of ethanolic extract derived from Dictyota dichotoma (Hudson) J.V. Lamouroux, 1809. M.Sc. thesis submitted to Mariano Marcos State University"},{"key":"6556_CR32","first-page":"4159","volume":"13","author":"S Packirisamy","year":"2022","unstructured":"Packirisamy S, Magdaline BL, Dhanavel A, Rajendiran D, Vijayashree RJ (2022) Preliminary screening and evaluation of Commiphora caudata leaf extract on cariogenic pathogens. Int J Pharm Sci Res 13:4159\u20134165","journal-title":"Int J Pharm Sci Res"},{"key":"6556_CR33","first-page":"81","volume":"4","author":"RK Shah","year":"2015","unstructured":"Shah RK, Yadav RNS (2015) Qualitative phytochemical analysis and Estimation of total phenols and flavonoids in leaf extract of Sarcochlamys pulcherrima Wedd. Glob J Biosci Biotechnol 4:81\u201384","journal-title":"Glob J Biosci Biotechnol"},{"key":"6556_CR34","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.fsi.2012.10.020","volume":"34","author":"YR Wu","year":"2013","unstructured":"Wu YR, Gong QF, Fang H, Liang WW, Chen M, He RJ (2013) Effect of sophora flavescens on non-specific immune response of tilapia (GIFT Oreochromis niloticus) and disease resistance against Streptococcus agalactiae. Fish Shellfish Immunol 34:220\u2013227","journal-title":"Fish Shellfish Immunol"},{"key":"6556_CR35","doi-asserted-by":"publisher","unstructured":"Periyannan K, Panchavarnam S, Bagthasingh C et al (2025) Protective and haemato-immunological effect of seaweed crude extracts against Tilapia Lake Virus (TiLV) in Nile tilapia, Oreochromis niloticus. Aquaculture International 2024 33:2 33:1\u201332. https:\/\/doi.org\/10.1007\/S10499-024-01795-8","DOI":"10.1007\/S10499-024-01795-8"},{"key":"6556_CR36","doi-asserted-by":"publisher","first-page":"109577","DOI":"10.1016\/j.fsi.2024.109577","volume":"149","author":"P Michael","year":"2024","unstructured":"Michael P, Panchavarnam S, Bagthasingh C et al (2024) Innate immune response of Snakehead fish to Indian strain of Snakehead rhabdovirus (SHRV-In) infection and the infectivity potential of the virus to other freshwater fishes. Fish Shellfish Immunol 149:109577","journal-title":"Fish Shellfish Immunol"},{"key":"6556_CR37","doi-asserted-by":"publisher","first-page":"738962","DOI":"10.1016\/j.aquaculture.2022.738962","volume":"563","author":"L Haridas","year":"2023","unstructured":"Haridas L, George MR, John KR et al (2023) Early innate immune responses of nile tilapia (Oreochromis niloticus) during tilapia lake virus (TiLV) infection. Aquaculture 563:738962","journal-title":"Aquaculture"},{"key":"6556_CR38","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1093\/nar\/29.9.e45","volume":"29","author":"MW Pfaffl","year":"2001","unstructured":"Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:2002\u20132007","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"6556_CR39","first-page":"75","volume":"3","author":"P Sivasankar","year":"2015","unstructured":"Sivasankar P, Santhiya AV, Kanaga V (2015) A review on plants and herbal extracts against viral diseases in aquaculture. J Med Plants Stud 3(2):75\u201379","journal-title":"J Med Plants Stud"},{"key":"6556_CR40","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/j.virusres.2018.06.002","volume":"255","author":"C Cheng","year":"2018","unstructured":"Cheng C, Yu-Feng S, Yang H, Lei L, Wei-Chao C, Gao-Xue W, Bin Z (2018) Highly efficient Inhibition of spring viraemia of carp virus replication in vitro mediated by bavachin, a major constituent of Psoralea Corylifolia Lynn. Virus Res 255:24\u201335","journal-title":"Virus Res"},{"key":"6556_CR41","unstructured":"Burgos-Aceves MA, Lionetti L, Faggio C (2019) Multidisciplinary haematology"},{"issue":"1","key":"6556_CR42","first-page":"83","volume":"18","author":"KR Grant","year":"2015","unstructured":"Grant KR (2015) Fish hematology and associated disorders. Veterinary Clinics: Exotic Anim Pract 18(1):83\u2013103","journal-title":"Veterinary Clinics: Exotic Anim Pract"},{"key":"6556_CR43","first-page":"633","volume":"1","author":"SM Hegazi","year":"2014","unstructured":"Hegazi SM, Fadl SE, Gad DM, Abeerd EKM (2014) Effect of Spirulina incorporated in diets of tilapia Nilotica freshwater fish exposed to lead toxicity. J Vet Sci 1:633\u2013649","journal-title":"J Vet Sci"},{"key":"6556_CR44","doi-asserted-by":"crossref","unstructured":"Vonshak A (ed) (1997) Spirulina platensis arthrospira: physiology, cell-biology and biotechnology. CRC","DOI":"10.1201\/9781482272970"},{"key":"6556_CR45","doi-asserted-by":"publisher","first-page":"1817","DOI":"10.1007\/s00204-016-1744-5","volume":"90","author":"Q Wu","year":"2016","unstructured":"Wu Q, Liu L, Miron A, Kl\u00edmov\u00e1 B, Wan D, Ku\u010da K (2016) The antioxidant, immunomodulatory, and anti-inflammatory activities of spirulina: an overview. Arch Toxicol 90:1817\u20131840","journal-title":"Arch Toxicol"},{"issue":"1","key":"6556_CR46","first-page":"53","volume":"3","author":"MA El Gammal","year":"2010","unstructured":"El Gammal MA, Shalaby AM, Ramadan AA (2010) The use of Spirulina platensis (microalgae) as a food additive to stimulate growth and immunity modulation for nile tilapia (Oreochromus niloticus) challenged with pathogenic bacteria (Pseudomonas fluorescence). Abbassa Int J Aquaculture 3(1):53\u201383","journal-title":"Abbassa Int J Aquaculture"},{"issue":"1","key":"6556_CR47","doi-asserted-by":"publisher","first-page":"27","DOI":"10.33899\/ijvs.2019.125527.1049","volume":"33","author":"NM Abdulrahman","year":"2019","unstructured":"Abdulrahman NM, Hama Ameen HJ, Hama SR, Hassan BR, Nader PJ (2019) Effect of microalgae Spirulina spp. As food additive on some biological and blood parameters of common carp Cyprinus Carpio L. Iraqi J Veterinary Sci 33(1):27\u201331","journal-title":"Iraqi J Veterinary Sci"},{"key":"6556_CR48","doi-asserted-by":"crossref","unstructured":"Fawole FJ, Yisa RO, Jayeoba OO, Adeshina I, Ahmed AO, Emikpe BO (2022) Effect of dietary polyherbal mixture on growth performance, haemato-immunological indices, antioxidant responses, and intestinal morphometry of African catfish, Clarias gariepinus","DOI":"10.1155\/2022\/5502796"},{"issue":"2","key":"6556_CR49","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1242\/jeb.46.2.297","volume":"46","author":"GF Holeton","year":"1967","unstructured":"Holeton GF, Randall DJ (1967) Changes in blood pressure in the rainbow trout during hypoxia. J Exp Biol 46(2):297\u2013305","journal-title":"J Exp Biol"},{"key":"6556_CR50","first-page":"203","volume":"11","author":"A Pathiratne","year":"1998","unstructured":"Pathiratne A, Rajapakshe W (1998) Hematological changes associated with epizootic ulcerative syndrome in the Asian cichlid Sh Etroplus suratensis. Asian Fish Sci 11:203\u2013211","journal-title":"Asian Fish Sci"},{"key":"6556_CR51","doi-asserted-by":"crossref","unstructured":"Chaklader et al (2024) Silybum marianum promotes growth, hepatic antioxidative activity, and splenic immunity but does not influence the intestinal barrier function of Nile tilapia, Oreochromis niloticus","DOI":"10.1016\/j.aquaculture.2024.740554"},{"key":"6556_CR52","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1111\/j.1095-8649.1988.tb05361.x","volume":"32","author":"L Tort","year":"1988","unstructured":"Tort L, Torres P, Hidalgo J (1988) The effects of sublethal concentrations of cadmium on haematological parameters in the dog Sh Scyliorhinus canicula. J Fish Biol 32:277\u2013282","journal-title":"J Fish Biol"},{"key":"6556_CR53","first-page":"49","volume":"49","author":"A Soivio","year":"1981","unstructured":"Soivio A, Nikinmaa M (1981) Kirjolohen fysiologisesta Tilasto Kuljetuksen Ja Sita Seuraavan Toipumisen Aikana (The physiological condition of rainbow trout during transport and the subsequent recovery period). Suomen Kalatalous 49:49\u201356","journal-title":"Suomen Kalatalous"},{"issue":"4\u20135","key":"6556_CR54","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1111\/j.1751-1097.1978.tb06969.x","volume":"28","author":"JF Rabek","year":"1978","unstructured":"Rabek JF, R\u00e5nby B (1978) The role of singlet oxygen in the photooxidation of polymers. Photochem Photobiol 28(4\u20135):557\u2013569","journal-title":"Photochem Photobiol"},{"issue":"1\u20133","key":"6556_CR55","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/S0044-8486(00)00420-8","volume":"191","author":"M Mu\u00f1oz","year":"2000","unstructured":"Mu\u00f1oz M, Cedeno R, Rodr\u00edguez J, van der Knaap WP, Mialhe E, Bachere E (2000) Measurement of reactive oxygen intermediate production in haemocytes of the Penaeid shrimp, Penaeus vannamei. Aquaculture 191(1\u20133):89\u2013107","journal-title":"Aquaculture"},{"key":"6556_CR56","doi-asserted-by":"crossref","unstructured":"Forman HJ, Torres M (2001) Redox signaling in macrophages. Molecular Aspects","DOI":"10.1007\/978-1-4615-1087-1_6"},{"issue":"12","key":"6556_CR57","doi-asserted-by":"publisher","first-page":"1505","DOI":"10.1111\/jfd.13251","volume":"43","author":"MA El-Son","year":"2020","unstructured":"El-Son MA, Elbahnaswy S, Ibrahim I (2020) Molecular and histopathological characterization of Photobacterium damselae in naturally and experimentally infected nile tilapia (Oreochromis niloticus). J Fish Dis 43(12):1505\u20131517","journal-title":"J Fish Dis"},{"issue":"7","key":"6556_CR58","doi-asserted-by":"publisher","first-page":"1249","DOI":"10.1016\/j.tiv.2009.07.031","volume":"23","author":"S Misra","year":"2009","unstructured":"Misra S, Niyogi S (2009) Selenite causes cytotoxicity in rainbow trout (Oncorhynchus mykiss) hepatocytes by inducing oxidative stress. Toxicol Vitro 23(7):1249\u20131258","journal-title":"Toxicol Vitro"},{"key":"6556_CR59","doi-asserted-by":"crossref","unstructured":"Fridovich I (1998) Oxygen toxicity: a radical explanation. J Experimental","DOI":"10.1242\/jeb.201.8.1203"},{"key":"6556_CR60","doi-asserted-by":"publisher","first-page":"827","DOI":"10.5012\/bkcs.2007.28.5.827","volume":"28","author":"MAA Rahman","year":"2007","unstructured":"Rahman MAA, Moon SS (2007) Antioxidant polyphenol glycosides from the plant Draba Nemorosa. Bull Korean Chem Soc 28:827\u2013831","journal-title":"Bull Korean Chem Soc"},{"key":"6556_CR61","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.fsi.2018.05.009","volume":"79","author":"G Ashouri","year":"2018","unstructured":"Ashouri G, Soofiani NM, Hoseinifar SH, Jalali SAH, Morshedi V, Van Doan H, Mozanzadeh MT (2018) Combined effects of dietary low molecular weight sodium alginate and Pediococcus acidilactici MA18\/5\u00a0M on growth performance, haematological and innate immune responses of Asian sea bass (Lates calcalifer) juveniles. Fish Shellfish Immunol 79:34\u201341","journal-title":"Fish Shellfish Immunol"},{"key":"6556_CR62","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1016\/j.fsi.2019.03.038","volume":"89","author":"ME Yonar","year":"2019","unstructured":"Yonar ME, Yonar SM, \u0130spir \u00dc, Ural M\u015e (2019) Effects of Curcumin on haematological values, immunity, antioxidant status and resistance of rainbow trout (Oncorhynchus mykiss) against Aeromonas salmonicida subsp. Achromogenes. Fish Shellfish Immunol 89:83\u201390","journal-title":"Fish Shellfish Immunol"},{"key":"6556_CR63","doi-asserted-by":"publisher","first-page":"100353","DOI":"10.1016\/j.aqrep.2020.100353","volume":"17","author":"G Sattanathan","year":"2020","unstructured":"Sattanathan G, Palanisamy T, Padmapriya S, Arumugam VA, Park S, Kim IH, Balasubramanian B (2020) Influences of dietary inclusion of algae Chaetomorpha aerea enhanced growth performance, immunity, haematological response and disease resistance of Labeo Rohita challenged with Aeromonas hydrophila. Aquac Rep 17:100353","journal-title":"Aquac Rep"},{"issue":"2","key":"6556_CR64","doi-asserted-by":"publisher","first-page":"354","DOI":"10.3390\/antiox12020354","volume":"12","author":"F Chen","year":"2023","unstructured":"Chen F, Chen L, Liang J, Chen Z, Zhang C, Zhang Z, Yang J (2023) Potential role of superoxide dismutase 3 (SOD3) in resistance to influenza A virus infection. Antioxidants 12(2):354","journal-title":"Antioxidants"},{"issue":"4","key":"6556_CR65","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.aquatox.2006.04.005","volume":"78","author":"TV Bagnyukova","year":"2006","unstructured":"Bagnyukova TV, Chahrak OI, Lushchak VI (2006) Coordinated response of goldfish antioxidant defenses to environmental stress. Aquat Toxicol 78(4):325\u2013331","journal-title":"Aquat Toxicol"},{"issue":"4","key":"6556_CR66","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1006\/fsim.1998.0192","volume":"9","author":"AE Ellis","year":"1999","unstructured":"Ellis AE (1999) Immunity to bacteria in fish. Fish Shellfish Immunol 9(4):291\u2013308","journal-title":"Fish Shellfish Immunol"},{"key":"6556_CR67","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1007\/BF02778986","volume":"56","author":"E Peterhans","year":"1997","unstructured":"Peterhans E (1997) Reactive oxygen species and nitric oxide in viral diseases. Biol Trace Elem Res 56:107\u2013116","journal-title":"Biol Trace Elem Res"},{"key":"6556_CR68","doi-asserted-by":"crossref","unstructured":"Kim SS, Lee KJ (2008) Effects of dietary Kelp (Ecklonia cava) on growth and innate immunity in juvenile Olive flounder Paralichthys Olivaceus (Temminck et Schlegel). Aquac Res, 39(15)","DOI":"10.1111\/j.1365-2109.2008.02046.x"},{"issue":"2","key":"6556_CR69","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.fsi.2012.05.018","volume":"33","author":"R Harikrishnan","year":"2012","unstructured":"Harikrishnan R, Kim DH, Hong SH, Mariappan P, Balasundaram C, Heo MS (2012) Non-specific immune response and disease resistance induced by siegesbeckia glabrescens against vibrio parahaemolyticus in epinephelus Bruneus. Fish Shellfish Immunol 33(2):359\u2013364","journal-title":"Fish Shellfish Immunol"},{"issue":"1","key":"6556_CR70","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.fsi.2015.01.038","volume":"44","author":"K Wang","year":"2015","unstructured":"Wang K, Fang X, Ma N, Lin Q, Huang Z, Liu W, Xu M, Chen X, Zhang W, Zhang Y (2015) Myeloperoxidase-deficient zebrafish show an augmented inflammatory response to challenge with Candida albicans. Fish Shellfish Immunol 44(1):109\u2013116","journal-title":"Fish Shellfish Immunol"},{"issue":"15","key":"6556_CR71","doi-asserted-by":"publisher","first-page":"5598","DOI":"10.1073\/pnas.0400937101","volume":"101","author":"JM Lund","year":"2004","unstructured":"Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, Iwasaki A, Flavell RA (2004) Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci 101(15):5598\u20135603","journal-title":"Proc Natl Acad Sci"},{"issue":"6","key":"6556_CR72","doi-asserted-by":"publisher","first-page":"1127","DOI":"10.1016\/j.fsi.2007.06.005","volume":"23","author":"SK Whyte","year":"2007","unstructured":"Whyte SK (2007) The innate immune response of finfish\u2013a review of current knowledge. Fish Shellfish Immunol 23(6):1127\u20131151","journal-title":"Fish Shellfish Immunol"},{"issue":"1\u20134","key":"6556_CR73","first-page":"1","volume":"317","author":"R Harikrishnan","year":"2011","unstructured":"Harikrishnan R, Balasundaram C, Heo MS (2011) Impact of plant products on innate and adaptive immune system of cultured finfish and shellfish. Aquaculture 317(1\u20134):1\u201315","journal-title":"Aquaculture"},{"key":"6556_CR74","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/j.fsi.2021.02.005","volume":"111","author":"N Sood","year":"2021","unstructured":"Sood N, Verma DK, Paria A, Yadav SC, Yadav MK, Bedekar MK, Kumar S, Swaminathan TR, Mohan CV, Rajendran KV (2021) Transcriptome analysis of liver elucidates key immune-related pathways in nile tilapia Oreochromis niloticus following infection with tilapia lake virus. Fish Shellfish Immunol 111:208\u2013219","journal-title":"Fish Shellfish Immunol"},{"issue":"12","key":"6556_CR75","doi-asserted-by":"publisher","first-page":"1336","DOI":"10.1016\/j.dci.2011.05.001","volume":"35","author":"CJ Secombes","year":"2011","unstructured":"Secombes CJ, Wang T, Bird S (2011) The interleukins of fish. Dev Comp Immunol 35(12):1336\u20131345","journal-title":"Dev Comp Immunol"},{"issue":"12","key":"6556_CR76","doi-asserted-by":"publisher","first-page":"1376","DOI":"10.1016\/j.dci.2011.07.001","volume":"35","author":"J Zou","year":"2011","unstructured":"Zou J, Secombes CJ (2011) Teleost fish interferons and their role in immunity. Dev Comp Immunol 35(12):1376\u20131387","journal-title":"Dev Comp Immunol"}],"container-title":["Archives of Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-026-06556-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00705-026-06556-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00705-026-06556-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T13:02:24Z","timestamp":1774962144000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00705-026-06556-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":76,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["6556"],"URL":"https:\/\/doi.org\/10.1007\/s00705-026-06556-x","relation":{},"ISSN":["0304-8608","1432-8798"],"issn-type":[{"value":"0304-8608","type":"print"},{"value":"1432-8798","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,27]]},"assertion":[{"value":"15 May 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 January 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"\u201cThe manuscript has been read, understood, and has complied as applicable with the statement on \u2018Ethical responsibilities of Authors\u2019 as found in the Instructions for Authors and the authors are aware that with minor exceptions, no changes can be made to authorship once the paper is submitted.\u201d","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}},{"value":"The authors declare no competing interest.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"105"}}