{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:33:32Z","timestamp":1762508012963},"reference-count":64,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T00:00:00Z","timestamp":1583193600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T00:00:00Z","timestamp":1583193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Protoplasma"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1007\/s00709-020-01495-z","type":"journal-article","created":{"date-parts":[[2020,3,3]],"date-time":"2020-03-03T11:02:46Z","timestamp":1583233366000},"page":"1049-1067","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Plasmodium falciparum DDX55 is a nucleocytoplasmic protein and a 3\u2032-5\u2032 direction-specific DNA helicase"],"prefix":"10.1007","volume":"257","author":[{"given":"Rahena","family":"Yasmin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inderjeet","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renu","family":"Tuteja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,3,3]]},"reference":[{"key":"1495_CR1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0049385","volume":"7","author":"M Ahmad","year":"2012","unstructured":"Ahmad M, Ansari A, Tarique M, Satsangi AT, Tuteja R (2012) Plasmodium falciparum UvrD helicase translocates in 3\u2032 to 5\u2032 direction, colocalizes with MLH and modulates its activity through physical interaction. PLoS One 7:1\u201321. https:\/\/doi.org\/10.1371\/journal.pone.0049385","journal-title":"PLoS One"},{"key":"1495_CR2","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1093\/bioinformatics\/bti770","volume":"22","author":"K Arnold","year":"2006","unstructured":"Arnold K, Bordoli L, Kopp J, Schwede T (2006) The SWISS-MODEL workspace: a web based environment for protein structure homology modeling. Bioinformatics 22:195\u2013201. https:\/\/doi.org\/10.1093\/bioinformatics\/bti770","journal-title":"Bioinformatics"},{"key":"1495_CR3","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1093\/nar\/gkl198","volume":"34","author":"TL Bailey","year":"2006","unstructured":"Bailey TL, Williams N, Misleh C, Li WW (2006) MEME: discovering and analyzing DNA and protein sequence motifs. Nucleic Acids Res 34:369\u2013373. https:\/\/doi.org\/10.1093\/nar\/gkl198","journal-title":"Nucleic Acids Res"},{"key":"1495_CR4","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1111\/cmi.12604","volume":"18","author":"S Bennink","year":"2016","unstructured":"Bennink S, Kiesowand MJ, Pradel G (2016) The development of malaria parasites in the mosquito midgut. Cell Microbiol 18:905\u2013918. https:\/\/doi.org\/10.1111\/cmi.12604","journal-title":"Cell Microbiol"},{"key":"1495_CR5","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1038\/nm.4381","volume":"23","author":"B Blasco","year":"2017","unstructured":"Blasco B, Leroy D, Fidock DA (2017) Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic. Nat Med 23:917\u2013928. https:\/\/doi.org\/10.1038\/nm.4381","journal-title":"Nat Med"},{"key":"1495_CR6","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1016\/s0035-9203(02)90346-9","volume":"96","author":"F Checchi","year":"2002","unstructured":"Checchi F, Durand R, Balkan S, Vonhm BT, Kollie JZ, Biberson P, Baron E, Le Bras J, Guthmann JP (2002) High Plasmodium falciparum resistance to chloroquine and sulfadoxine-pyrimethamine in Harper, Liberia: results in vivo and analysis of point mutations. Trans R Soc Trop Med Hyg 96:664\u2013669. https:\/\/doi.org\/10.1016\/s0035-9203(02)90346-9","journal-title":"Trans R Soc Trop Med Hyg"},{"key":"1495_CR7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.gene.2005.10.019","volume":"367","author":"O Cordin","year":"2006","unstructured":"Cordin O, Banroques J, Tanner NK, Linder P (2006) The DEAD box protein family of RNA helicases. Gene 367:17\u201337. https:\/\/doi.org\/10.1016\/j.gene.2005.10.019","journal-title":"Gene"},{"key":"1495_CR8","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1016\/j.cell.2016.07.055","volume":"167","author":"AF Cowman","year":"2016","unstructured":"Cowman AF, Healer J, Marapana D, Marsh K (2016) Malaria: biology and disease. Cell 167:610\u2013624. https:\/\/doi.org\/10.1016\/j.cell.2016.07.055","journal-title":"Cell"},{"key":"1495_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmolb.2018.00059","volume":"5","author":"A Datta","year":"2018","unstructured":"Datta A, Brosh RM (2018) New insights in to DNA helicases as druggable targets for cancer therapy. Front Mol Biosci 5:1\u201329. https:\/\/doi.org\/10.3389\/fmolb.2018.00059","journal-title":"Front Mol Biosci"},{"key":"1495_CR10","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1017\/s1355838298981158","volume":"4","author":"J De la Cruz","year":"1998","unstructured":"De la Cruz J, Kressler D, Rojo M, Tollervey D, Linder P (1998) Spb4p, an essential putative RNA helicase, is required for a late step in the assembly of 60S ribosomal subunits in Saccharomyces cerevisiae. RNA 4:1268\u20131281. https:\/\/doi.org\/10.1017\/s1355838298981158","journal-title":"RNA"},{"key":"1495_CR11","doi-asserted-by":"publisher","first-page":"7889","DOI":"10.1093\/nar\/gkt545","volume":"41","author":"JA Dembowski","year":"2013","unstructured":"Dembowski JA, Kuo B, Woolford JL (2013) Has1 regulates consecutive maturation and processing steps for assembly of 60S ribosomal subunits. Nucleic Acids Res 41:7889\u20137904. https:\/\/doi.org\/10.1093\/nar\/gkt545","journal-title":"Nucleic Acids Res"},{"key":"1495_CR12","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1093\/nar\/gkn180","volume":"36","author":"A Dereeper","year":"2008","unstructured":"Dereeper A, Guignon V, Blanc G, Audic S, Buffet S, Chevenet F, Dufayard JF, Guindon S, Lefort V, Lescot M, Claverie JM, Gascuel O (2008) Phylogeny.fr: robust phylogenetic analysis for the non-specialist. Nucleic Acids Res 36:465\u2013469","journal-title":"Nucleic Acids Res"},{"key":"1495_CR13","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1056\/NEJMoa0808859","volume":"361","author":"AM Dondorp","year":"2009","unstructured":"Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, Lwin KM, Ariey F, Hanpithakpong W, Lee SJ (2009) Artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med 361:455\u2013467. https:\/\/doi.org\/10.1056\/NEJMoa0808859","journal-title":"N Engl J Med"},{"key":"1495_CR14","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1002\/med.20082","volume":"26","author":"K Ersmark","year":"2006","unstructured":"Ersmark K, Samuelsson B, Hallberg A (2006) Plasmepsins as potential targets for new antimalarial therapy. Med Res Rev 26:626\u2013666. https:\/\/doi.org\/10.1002\/med.20082","journal-title":"Med Res Rev"},{"key":"1495_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3791\/2359","volume":"44","author":"A Eslami","year":"2010","unstructured":"Eslami A, Lujan J (2010) Western blotting: sample preparation to detection. J Vis Exp 44:1\u20132. https:\/\/doi.org\/10.3791\/2359","journal-title":"J Vis Exp"},{"key":"1495_CR16","doi-asserted-by":"publisher","first-page":"3695","DOI":"10.1093\/emboj\/20.14.3695","volume":"20","author":"O Gadal","year":"2001","unstructured":"Gadal O, Strauss D, Braspenning J, Hoepfner D, Petfalski E, Philippsen P, Tollervey D, Hurt E (2001) A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits. EMBO J 20:3695\u20133704. https:\/\/doi.org\/10.1093\/emboj\/20.14.3695","journal-title":"EMBO J"},{"key":"1495_CR17","doi-asserted-by":"publisher","first-page":"4156","DOI":"10.1128\/MCB.05436-11","volume":"31","author":"JJ Garc\u00eda-G\u00f3mez","year":"2011","unstructured":"Garc\u00eda-G\u00f3mez JJ, Lebaron S, Froment C, Monsarrat B, Henry Y, de la Cruz J (2011) Dynamics of the putative RNA helicase Spb4 during ribosome assembly in Saccharomyces cerevisiae. Mol Cell Biol 31:4156\u20134164. https:\/\/doi.org\/10.1128\/MCB.05436-11","journal-title":"Mol Cell Biol"},{"key":"1495_CR18","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1038\/nature01097","volume":"419","author":"MJ Gardner","year":"2002","unstructured":"Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden G, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419:498\u2013511. https:\/\/doi.org\/10.1038\/nature01097","journal-title":"Nature"},{"key":"1495_CR19","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1016\/S0959-440X(05)80116-2","volume":"3","author":"AE Gorbalenya","year":"1993","unstructured":"Gorbalenya AE, Koonin EV (1993) Helicases: amino acid sequence comparisons and structure-function relationships. Curr Opin Struct Biol 3:419\u2013429. https:\/\/doi.org\/10.1016\/S0959-440X(05)80116-2","journal-title":"Curr Opin Struct Biol"},{"key":"1495_CR20","doi-asserted-by":"publisher","unstructured":"Heerma van Voss MR, Vesuna F, Trumpi K, Brilliant J, Berlinicke C, de Leng W, Kranenburg O, Offerhaus GJ, B\u00fcrger H, van der Wall E, van Diest PJ, Raman V (2015) Identification of the DEAD box RNA helicase DDX3 as a therapeutic target in colorectal cancer. Oncotarget 6:28312\u201328326. https:\/\/doi.org\/10.18632\/oncotarget.4873","DOI":"10.18632\/oncotarget.4873"},{"key":"1495_CR21","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12936-019-2730-1","volume":"88","author":"DS Ishengoma","year":"2019","unstructured":"Ishengoma DS, Mandara CI, Francis F, Talundzic E, Lucchi NW, Ngasala B, Kabanywanyi AM, Mahende MK, Kamugisha E, Kavishe RA, Muro F, Mohamed A, Mandike R, Mkude S, Chacky F, Paxton L, Greer G, Kitojo CA, Njau R, Martin T, Venkatesan M, Warsame M, Halsey ES, Udhayakumar V (2019) Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria and prevalence of Pfk13 and Pfmdr1 polymorphisms after a decade of using artemisinin-based combination therapy in mainland Tanzania. Malar J 88:1\u201313. https:\/\/doi.org\/10.1186\/s12936-019-2730-1","journal-title":"Malar J"},{"key":"1495_CR22","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.tibs.2010.07.008","volume":"36","author":"E Jankowsky","year":"2011","unstructured":"Jankowsky E (2011) RNA helicases at work: binding and rearranging. Trends Biochem Sci 36:19\u201329. https:\/\/doi.org\/10.1016\/j.tibs.2010.07.008","journal-title":"Trends Biochem Sci"},{"key":"1495_CR23","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.sbi.2007.05.007","volume":"17","author":"E Jankowsky","year":"2007","unstructured":"Jankowsky E, Fairman ME (2007) RNA helicases- one-fold for many functions. Curr Opin Struct Biol 17:316\u2013324. https:\/\/doi.org\/10.1016\/j.sbi.2007.05.007","journal-title":"Curr Opin Struct Biol"},{"key":"1495_CR24","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1021\/bi701048a","volume":"47","author":"TA Jennings","year":"2008","unstructured":"Jennings TA, Chen Y, Sikora D, Harrison MK, Sikora B, Huang L, Jankowsky E, Fairman ME, Cameron CE, Raney KD (2008) RNA unwinding activity of the hepatitis C virus NS3 helicase is modulated by the NS5B polymerase. Biochemistry 47:1126\u20131135. https:\/\/doi.org\/10.1021\/bi701048a","journal-title":"Biochemistry"},{"key":"1495_CR25","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1016\/0092-8674(84)90457-4","volume":"39","author":"D Kalderon","year":"1984","unstructured":"Kalderon D, Roberts BL, Richardson WD, Smith AE (1984) A short amino acid sequence able to specify nuclear location. Cell 39:499\u2013509. https:\/\/doi.org\/10.1016\/0092-8674(84)90457-4","journal-title":"Cell"},{"key":"1495_CR26","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.ijantimicag.2012.12.007","volume":"41","author":"EY Klein","year":"2013","unstructured":"Klein EY (2013) Antimalarial drug resistance: a review of the biology and strategies to delay emergence and spread. Int J Antimicrob Agents 41:311\u2013317. https:\/\/doi.org\/10.1016\/j.ijantimicag.2012.12.007","journal-title":"Int J Antimicrob Agents"},{"key":"1495_CR27","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1006\/abbi.1999.1248","volume":"367","author":"K Kusano","year":"1999","unstructured":"Kusano K, Waterman MR, Sakaguchi M, Omura T, Kagawa N (1999) Protein synthesis inhibitors and ethanol selectively enhance heterologous expression of P450s and related proteins in Escherichia coli. Arch Biochem Biophys 367:129\u2013136. https:\/\/doi.org\/10.1006\/abbi.1999.1248","journal-title":"Arch Biochem Biophys"},{"key":"1495_CR28","doi-asserted-by":"publisher","first-page":"418","DOI":"10.2307\/3280287","volume":"65","author":"C Lambros","year":"1979","unstructured":"Lambros C, Vanderberg JP (1979) Synchronization of Plasmodium falciparum. J Parasitol 65:418\u2013420. https:\/\/doi.org\/10.2307\/3280287","journal-title":"J Parasitol"},{"key":"1495_CR29","doi-asserted-by":"publisher","first-page":"39679","DOI":"10.1074\/jbc.C200337200","volume":"277","author":"CG Lee","year":"2002","unstructured":"Lee CG (2002) RH70, a bidirectional RNA helicase, co-purifies with U1snRNP*. J Biol Chem 277:39679\u201339683. https:\/\/doi.org\/10.1074\/jbc.C200337200","journal-title":"J Biol Chem"},{"key":"1495_CR30","doi-asserted-by":"publisher","first-page":"4374","DOI":"10.1128\/AAC.00666-08","volume":"52","author":"AM Lehane","year":"2008","unstructured":"Lehane AM, Kirk K (2008) Chloroquine resistance-conferring mutations in pfcrt give rise to a chloroquine-associated H+ leak from the malaria parasite\u2019s digestive vacuole. Antimicrob Agents Chemother 52:4374\u20134380. https:\/\/doi.org\/10.1128\/AAC.00666-08","journal-title":"Antimicrob Agents Chemother"},{"key":"1495_CR31","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.brainres.2016.02.047","volume":"1647","author":"Y Li","year":"2016","unstructured":"Li Y, Collins M, An J, Geiser R, Tegeler T, Tsantilas K, Garcia K, Pirrotte P, Bowser R (2016) Immunoprecipitation and mass spectrometry defines an extensive RBM45 protein\u2013protein interaction network. Brain Res 1647:79\u201393. https:\/\/doi.org\/10.1016\/j.brainres.2016.02.047","journal-title":"Brain Res"},{"key":"1495_CR32","doi-asserted-by":"publisher","first-page":"1","DOI":"10.7554\/eLife.04630","volume":"3","author":"AL Mallam","year":"2014","unstructured":"Mallam AL, Sidote DJ, Lambowitz AM (2014) Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife 3:1\u201318. https:\/\/doi.org\/10.7554\/eLife.04630","journal-title":"Elife"},{"key":"1495_CR33","doi-asserted-by":"publisher","first-page":"583","DOI":"10.3347\/kjp.2015.53.5.583","volume":"53","author":"LA Marchat","year":"2015","unstructured":"Marchat LA, Arzola-Rodr\u00edguez SI, Hernandez-de la Cruz O, Lopez-Rosas I, Lopez-Camarillo C (2015) DEAD\/DExH-box RNA helicases in selected human parasites. Korean J Parasitol 53:583\u2013595. https:\/\/doi.org\/10.3347\/kjp.2015.53.5.583","journal-title":"Korean J Parasitol"},{"key":"1495_CR34","doi-asserted-by":"publisher","first-page":"181","DOI":"10.4269\/ajtmh.2007.77.181","volume":"77","author":"F Nosten","year":"2007","unstructured":"Nosten F, White NJ (2007) Artemisinin-based combination treatment of falciparum malaria. Am J Trop Med Hyg 77:181\u2013192. https:\/\/doi.org\/10.4269\/ajtmh.2007.77.181","journal-title":"Am J Trop Med Hyg"},{"key":"1495_CR35","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1002\/jcc.20084","volume":"25","author":"EF Pettersen","year":"2004","unstructured":"Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, Ferrin TE (2004) UCSF Chimera\u2014a visualization system for exploratory research and analysis. J Comput Chem 25:1605\u20131612. https:\/\/doi.org\/10.1002\/jcc.20084","journal-title":"J Comput Chem"},{"key":"1495_CR36","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1016\/j.molbiopara.2005.08.006","volume":"144","author":"A Pradhan","year":"2005","unstructured":"Pradhan A, Chauhan VS, Tuteja R (2005) Plasmodium falciparum DNA helicase 60 is a schizont stage specific, bipolar and dual helicase stimulated by PKC phosphorylation. Mol Biochem Parasitol 144:133\u2013141. https:\/\/doi.org\/10.1016\/j.molbiopara.2005.08.006","journal-title":"Mol Biochem Parasitol"},{"key":"1495_CR37","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1016\/j.parint.2010.02.003","volume":"59","author":"K Prakash","year":"2010","unstructured":"Prakash K, Tuteja R (2010) A novel DEAD box helicase Has1p from Plasmodium falciparum: N-terminal is essential for activity. Parasitol Int 59:271\u2013277. https:\/\/doi.org\/10.1016\/j.parint.2010.02.003","journal-title":"Parasitol Int"},{"key":"1495_CR38","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1016\/j.bbagrm.2013.02.002","volume":"1829","author":"AA Putnam","year":"2013","unstructured":"Putnam AA, Jankowsky E (2013) DEAD-box helicases as integrators of RNA, nucleotide and protein binding. Biochim Biophys Acta 1829:884\u2013893. https:\/\/doi.org\/10.1016\/j.bbagrm.2013.02.002","journal-title":"Biochim Biophys Acta"},{"key":"1495_CR39","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1146\/annurev.biophys.37.032807.125908","volume":"37","author":"AM Pyle","year":"2008","unstructured":"Pyle AM (2008) Translocation and unwinding mechanisms of RNA and DNA helicases. Annu Rev Biophys 37:317\u2013336. https:\/\/doi.org\/10.1146\/annurev.biophys.37.032807.125908","journal-title":"Annu Rev Biophys"},{"key":"1495_CR40","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.cbpa.2011.07.019","volume":"15","author":"AM Pyle","year":"2011","unstructured":"Pyle AM (2011) RNA helicases and remodeling proteins. Curr Opin Chem Biol 15:636\u2013642. https:\/\/doi.org\/10.1016\/j.cbpa.2011.07.019","journal-title":"Curr Opin Chem Biol"},{"key":"1495_CR41","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1007\/s00709-015-0785-6","volume":"253","author":"F Rahman","year":"2015","unstructured":"Rahman F, Tarique M, Ahmad M, Tuteja R (2015) Plasmodium falciparum Werner homologue is a nuclear protein and its biochemical activities reside in the N-terminal region. Protoplasma 253:45\u201360. https:\/\/doi.org\/10.1007\/s00709-015-0785-6","journal-title":"Protoplasma"},{"key":"1495_CR42","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/978-1-4614-5037-5_2","volume":"767","author":"KD Raney","year":"2013","unstructured":"Raney KD, Byrd AK, Aarattuthodiyil S (2013) Structure and mechanisms of SF1 DNA helicases. Adv Exp Med Biol 767:17\u201346. https:\/\/doi.org\/10.1007\/978-1-4614-5037-5_2","journal-title":"Adv Exp Med Biol"},{"key":"1495_CR43","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1093\/nar\/gki244","volume":"33","author":"S Rocak","year":"2005","unstructured":"Rocak S, Emery B, Tanner NK, Linder P (2005) Characterization of the ATPase and unwinding activities of the yeast DEAD-box protein Has1p and the analysis of the roles of the conserved motifs. Nucleic Acids Res 33:999\u20131009. https:\/\/doi.org\/10.1093\/nar\/gki244","journal-title":"Nucleic Acids Res"},{"key":"1495_CR44","doi-asserted-by":"publisher","unstructured":"Rout S, Mahapatra RK (2019) Plasmodium falciparum: multidrug resistance. Chem Biol Drug Des:1\u201323. https:\/\/doi.org\/10.1111\/cbdd.13484","DOI":"10.1111\/cbdd.13484"},{"key":"1495_CR45","doi-asserted-by":"publisher","first-page":"4061","DOI":"10.1128\/mcb.9.9.4061","volume":"9","author":"F Rozen","year":"1989","unstructured":"Rozen F, Pelletier J, Trachsel H, Sonenberg N (1989) A lysine substitution in the ATP-binding site of eukaryotic initiation factor 4A abrogates nucleotide-binding activity. Mol Cell Biol 9:4061\u20134063. https:\/\/doi.org\/10.1128\/mcb.9.9.4061","journal-title":"Mol Cell Biol"},{"key":"1495_CR46","volume-title":"Molecular cloning: a laboratory manual","author":"J Sambrook","year":"1989","unstructured":"Sambrook J, Fritsch E, Maniatis TI (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor","edition":"2"},{"key":"1495_CR47","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1038\/nature26156","volume":"556","author":"Z Sanghai","year":"2018","unstructured":"Sanghai Z, Miller L, Molloy K, Barandun J, Hunziker M, Chaker-Margot M, Wang J, Chait BT, Klinge S (2018) Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature 556:126\u2013129. https:\/\/doi.org\/10.1038\/nature26156","journal-title":"Nature"},{"key":"1495_CR48","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1038\/nmeth.2089","volume":"9","author":"CA Schneider","year":"2012","unstructured":"Schneider CA, Rasband WS, Eliceiri KW (2012) NIH image to ImageJ: 25 years of image analysis. Nat Methods 9:671\u2013675. https:\/\/doi.org\/10.1038\/nmeth.2089","journal-title":"Nat Methods"},{"key":"1495_CR49","doi-asserted-by":"publisher","first-page":"9564","DOI":"10.1073\/pnas.0800418105","volume":"105","author":"P Sch\u00fctz","year":"2008","unstructured":"Sch\u00fctz P, Bumann M, Oberholzer AE, Bieniossek C, Trachsel H, Altmann M, Baumann U (2008) Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein\u2013protein interactions. Proc Natl Acad Sci 105:9564\u20139569. https:\/\/doi.org\/10.1073\/pnas.0800418105","journal-title":"Proc Natl Acad Sci"},{"key":"1495_CR50","doi-asserted-by":"publisher","first-page":"1819","DOI":"10.1128\/jb.184.7.1819-1826.2002","volume":"184","author":"MR Singleton","year":"2002","unstructured":"Singleton MR, Wigley DB (2002) Modularity and specialization in superfamily 1 and 2 helicases. J Bacteriol 184:1819\u20131826. https:\/\/doi.org\/10.1128\/jb.184.7.1819-1826.2002","journal-title":"J Bacteriol"},{"key":"1495_CR51","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1146\/annurev.biochem.76.052305.115300","volume":"76","author":"MR Singleton","year":"2007","unstructured":"Singleton MR, Dillingham MS, Wigley DB (2007) Structure and mechanism of helicases and nucleic acid translocases. Annu Rev Biochem 76:23\u201350. https:\/\/doi.org\/10.1146\/annurev.biochem.76.052305.115300","journal-title":"Annu Rev Biochem"},{"key":"1495_CR52","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1093\/nar\/gkw937","volume":"45","author":"D Szklarczyk","year":"2017","unstructured":"Szklarczyk D, Morris JH, Cook H, Kuhn M, Wyder S, Simonovic M, Santos A, Doncheva NT, Roth A, Bork P, Jensen LJ, von Mering C (2017) The STRING database in 2017: quality-controlled protein-protein association networks, made broadly accessible. Nucleic Acids Res 45:362\u2013368. https:\/\/doi.org\/10.1093\/nar\/gkw937","journal-title":"Nucleic Acids Res"},{"key":"1495_CR53","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1093\/infdis\/jiu491","volume":"211","author":"S Takala-Harrison","year":"2015","unstructured":"Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, Fukuda MM, Hien TT, Mayxay M, Noedl H (2015) Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia. J Infect Dis 211:670\u2013679. https:\/\/doi.org\/10.1093\/infdis\/jiu491","journal-title":"J Infect Dis"},{"key":"1495_CR54","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/S1097-2765(01)00329-X","volume":"8","author":"NK Tanner","year":"2001","unstructured":"Tanner NK, Linder P (2001) DExD\/ H box RNA helicases: from generic motors to specific dissociation functions. Mol Cell 8:251\u2013262. https:\/\/doi.org\/10.1016\/S1097-2765(01)00329-X","journal-title":"Mol Cell"},{"key":"1495_CR55","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1126\/science.781840","volume":"193","author":"W Trager","year":"1976","unstructured":"Trager W, Jensen JB (1976) Human malaria parasites in continuous culture. Science 193:673\u2013675. https:\/\/doi.org\/10.1126\/science.781840","journal-title":"Science"},{"key":"1495_CR56","doi-asserted-by":"publisher","first-page":"4699","DOI":"10.1111\/j.1742-4658.2007.06000.x","volume":"274","author":"R Tuteja","year":"2007","unstructured":"Tuteja R (2007) Helicases\u2014feasible antimalarial drug target for Plasmodium falciparum. FEBS J 274:4699\u20134704. https:\/\/doi.org\/10.1111\/j.1742-4658.2007.06000.x","journal-title":"FEBS J"},{"key":"1495_CR57","doi-asserted-by":"publisher","first-page":"104","DOI":"10.4161\/cc.9.1.10241","volume":"9","author":"R Tuteja","year":"2010","unstructured":"Tuteja R (2010) Genome wide identification of Plasmodium falciparum helicases: a comparison with human host. Cell Cycle 9:104\u2013120. https:\/\/doi.org\/10.4161\/cc.9.1.10241","journal-title":"Cell Cycle"},{"key":"1495_CR58","doi-asserted-by":"publisher","first-page":"2592","DOI":"10.1111\/febs.14109","volume":"284","author":"R Tuteja","year":"2017","unstructured":"Tuteja R (2017) Unraveling the importance of the malaria parasite helicases. FEBS J 284:2592\u20132603. https:\/\/doi.org\/10.1111\/febs.14109","journal-title":"FEBS J"},{"key":"1495_CR59","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.gene.2006.03.007","volume":"376","author":"R Tuteja","year":"2006","unstructured":"Tuteja R, Pradhan A (2006) Unraveling the \u2018DEAD-box\u2019 helicases of Plasmodium falciparum. Gene 376:1\u201312. https:\/\/doi.org\/10.1016\/j.gene.2006.03.007","journal-title":"Gene"},{"key":"1495_CR60","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1086\/322858","volume":"184","author":"TE Wellems","year":"2001","unstructured":"Wellems TE, Plowe CV (2001) Chloroquine-resistant malaria. J Infect Dis 184:770\u2013776. https:\/\/doi.org\/10.1086\/322858","journal-title":"J Infect Dis"},{"key":"1495_CR61","doi-asserted-by":"publisher","first-page":"793","DOI":"10.1016\/0140-6736(93)90565-X","volume":"341","author":"NJ White","year":"1993","unstructured":"White NJ (1993) Malaria parasites go ape. Lancet 341:793. https:\/\/doi.org\/10.1016\/0140-6736(93)90565-X","journal-title":"Lancet"},{"key":"1495_CR62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12936-017-1731-1","volume":"16","author":"NJ White","year":"2017","unstructured":"White NJ (2017) Malaria parasite clearance. Malar J 16:1\u201314. https:\/\/doi.org\/10.1186\/s12936-017-1731-1","journal-title":"Malar J"},{"key":"1495_CR63","unstructured":"WHO (2018) World malaria report 2018. https:\/\/www.who.int\/malaria\/publications\/world-malaria-report-2018\/en\/"},{"key":"1495_CR64","doi-asserted-by":"publisher","unstructured":"Yasmin R, Chauhan M, Sourabh S, Tuteja R (2019) Plasmodium falciparum DDX31 is DNA helicase localized in nucleolus. Heliyon 5. https:\/\/doi.org\/10.1016\/j.heliyon.2019.e02905","DOI":"10.1016\/j.heliyon.2019.e02905"}],"container-title":["Protoplasma"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00709-020-01495-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00709-020-01495-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00709-020-01495-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T01:14:47Z","timestamp":1614734087000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00709-020-01495-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,3]]},"references-count":64,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["1495"],"URL":"https:\/\/doi.org\/10.1007\/s00709-020-01495-z","relation":{},"ISSN":["0033-183X","1615-6102"],"issn-type":[{"value":"0033-183X","type":"print"},{"value":"1615-6102","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,3]]},"assertion":[{"value":"3 January 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 March 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}