{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T19:48:27Z","timestamp":1785527307576,"version":"3.56.0"},"reference-count":57,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T00:00:00Z","timestamp":1785196800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Postgraduate Science and Technology Innovation Program of Chongqing University of Science and Technology","award":["No. YKJCX2520613"],"award-info":[{"award-number":["No. YKJCX2520613"]}]},{"name":"Natural Science Foundation of Chongqing, China","award":["CSTB2022NSCQ-MSX1587"],"award-info":[{"award-number":["CSTB2022NSCQ-MSX1587"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Protoplasma"],"DOI":"10.1007\/s00709-026-02252-4","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:23:07Z","timestamp":1785208987000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exogenous sodium nitroprusside alleviates cadmium toxicity in Solanum nigrum via antioxidant activation, metal redistribution, and gene expression modulation"],"prefix":"10.1007","author":[{"given":"Fang","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinqun","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunqin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5026-8123","authenticated-orcid":false,"given":"Rui","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,28]]},"reference":[{"key":"2252_CR1","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s00709-017-1132-x","volume":"255","author":"P Ahmad","year":"2018","unstructured":"Ahmad P, Ahanger MA, Alyemeni MN et al (2018) Exogenous application of nitric oxide modulates osmolyte metabolism, antioxidants, enzymes of ascorbate-glutathione cycle and promotes growth under cadmium stress in tomato. Protoplasma 255:79\u201393. https:\/\/doi.org\/10.1007\/s00709-017-1132-x","journal-title":"Protoplasma"},{"key":"2252_CR2","doi-asserted-by":"publisher","first-page":"42","DOI":"10.3390\/toxics9030042","volume":"9","author":"A Alengebawy","year":"2021","unstructured":"Alengebawy A, Abdelkhalek ST, Qureshi SR, Wang M-Q (2021) Heavy metals and pesticides toxicity in agricultural soil and plants: ecological risks and human health implications. Toxics 9:42. https:\/\/doi.org\/10.3390\/toxics9030042","journal-title":"Toxics"},{"key":"2252_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2023.138081","volume":"417","author":"L Bai","year":"2023","unstructured":"Bai L, Ding S, Huang X et al (2023) Prediction of the cadmium content in grains of low-accumulating wheat cultivars and soil cadmium threshold for safe production. J Clean Prod 417:138081. https:\/\/doi.org\/10.1016\/j.jclepro.2023.138081","journal-title":"J Clean Prod"},{"key":"2252_CR4","doi-asserted-by":"publisher","first-page":"4319","DOI":"10.1093\/jxb\/erz352","volume":"70","author":"R Brouquisse","year":"2019","unstructured":"Brouquisse R (2019) Multifaceted roles of nitric oxide in plants. J Exp Bot 70:4319\u20134322. https:\/\/doi.org\/10.1093\/jxb\/erz352","journal-title":"J Exp Bot"},{"key":"2252_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.indcrop.2024.119359","volume":"221","author":"S Cao","year":"2024","unstructured":"Cao S, Pan J, Rehman M et al (2024) Exogenous nitric oxide alleviates cadmium toxicity in kenaf (Hibiscus cannabinus L.) through modulating Cd deposition and regulating key genes and involved pathways. Ind Crops Prod 221:119359. https:\/\/doi.org\/10.1016\/j.indcrop.2024.119359","journal-title":"Ind Crops Prod"},{"key":"2252_CR6","doi-asserted-by":"publisher","DOI":"10.3390\/plants14213264","volume":"14","author":"Y Chen","year":"2025","unstructured":"Chen Y, Sun Y, Cao B et al (2025) Exogenous nitric oxide promotes the growth and cadmium accumulation of alfalfa (Medicago sativa) seedlings under cadmium stress. Plants (Basel) 14:3264. https:\/\/doi.org\/10.3390\/plants14213264","journal-title":"Plants (Basel)"},{"key":"2252_CR7","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1080\/07352689.2014.903747","volume":"33","author":"G Choppala","year":"2014","unstructured":"Choppala G, Saifullah BN et al (2014) Cellular mechanisms in higher plants governing tolerance to cadmium toxicity. Crit Rev Plant Sci 33:374\u2013391. https:\/\/doi.org\/10.1080\/07352689.2014.903747","journal-title":"Crit Rev Plant Sci"},{"key":"2252_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2022.115878","volume":"320","author":"H Dai","year":"2022","unstructured":"Dai H, Wei S, Twardowska I et al (2022) Cosmopolitan cadmium hyperaccumulator Solanum nigrum: exploring cadmium uptake, transport and physiological mechanisms of accumulation in different ecotypes as a way of enhancing its hyperaccumulative capacity. J Environ Manage 320:115878. https:\/\/doi.org\/10.1016\/j.jenvman.2022.115878","journal-title":"J Environ Manage"},{"key":"2252_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2020.127564","volume":"260","author":"X Dou","year":"2020","unstructured":"Dou X, Dai H, Skuza L, Wei S (2020) Strong accumulation capacity of hyperaccumulator Solanum nigrum L. for low or insoluble Cd compounds in soil and its implication for phytoremediation. Chemosphere 260:127564. https:\/\/doi.org\/10.1016\/j.chemosphere.2020.127564","journal-title":"Chemosphere"},{"key":"2252_CR10","doi-asserted-by":"publisher","first-page":"675","DOI":"10.1080\/10643389.2020.1835435","volume":"52","author":"T El Rasafi","year":"2022","unstructured":"El Rasafi T, Oukarroum A, Haddioui A et al (2022) Cadmium stress in plants: a critical review of the effects, mechanisms, and tolerance strategies. Crit Rev Environ Sci Technol 52:675\u2013726. https:\/\/doi.org\/10.1080\/10643389.2020.1835435","journal-title":"Crit Rev Environ Sci Technol"},{"key":"2252_CR11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.131008","volume":"450","author":"P Fan","year":"2023","unstructured":"Fan P, Wu L, Wang Q et al (2023) Physiological and molecular mechanisms of medicinal plants in response to cadmium stress: current status and future perspective. J Hazard Mater 450:131008. https:\/\/doi.org\/10.1016\/j.jhazmat.2023.131008","journal-title":"J Hazard Mater"},{"key":"2252_CR12","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1016\/j.foodchem.2019.05.160","volume":"295","author":"Y Ge","year":"2019","unstructured":"Ge Y, Li X, Li C et al (2019) Effect of sodium nitroprusside on antioxidative enzymes and the phenylpropanoid pathway in blueberry fruit. Food Chem 295:607\u2013612. https:\/\/doi.org\/10.1016\/j.foodchem.2019.05.160","journal-title":"Food Chem"},{"key":"2252_CR13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.131039","volume":"450","author":"SA Ghuge","year":"2023","unstructured":"Ghuge SA, Nikalje GC, Kadam US et al (2023) Comprehensive mechanisms of heavy metal toxicity in plants, detoxification, and remediation. J Hazard Mater 450:131039. https:\/\/doi.org\/10.1016\/j.jhazmat.2023.131039","journal-title":"J Hazard Mater"},{"key":"2252_CR14","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28093921","volume":"28","author":"EA Goncharuk","year":"2023","unstructured":"Goncharuk EA, Zagoskina NV (2023) Heavy metals, their phytotoxicity, and the role of phenolic antioxidants in plant stress responses with focus on cadmium: review. Molecules 28:3921. https:\/\/doi.org\/10.3390\/molecules28093921","journal-title":"Molecules"},{"key":"2252_CR15","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1007\/s11104-019-04014-z","volume":"438","author":"MY Guan","year":"2019","unstructured":"Guan MY, Zhu YX, Liu XX, Jin CW (2019) Induction of S-nitrosoglutathione reductase reduces root cadmium uptake by inhibiting Iron-regulated transporter 1. Plant Soil 438:251\u2013262. https:\/\/doi.org\/10.1007\/s11104-019-04014-z","journal-title":"Plant Soil"},{"key":"2252_CR16","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/j.molp.2024.04.001","volume":"17","author":"KJ Gupta","year":"2024","unstructured":"Gupta KJ, Yadav N, Kumari A, Loake GJ (2024) New insights into nitric oxide biosynthesis underpin lateral root development. Mol Plant 17:691\u2013693. https:\/\/doi.org\/10.1016\/j.molp.2024.04.001","journal-title":"Mol Plant"},{"key":"2252_CR17","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/j.ecoenv.2014.05.021","volume":"108","author":"J He","year":"2014","unstructured":"He J, Ren Y, Chen X, Chen H (2014) Protective roles of nitric oxide on seed germination and seedling growth of rice (Oryza sativa L.) under cadmium stress. Ecotoxicol Environ Saf 108:114\u2013119. https:\/\/doi.org\/10.1016\/j.ecoenv.2014.05.021","journal-title":"Ecotoxicol Environ Saf"},{"key":"2252_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jenvman.2023.117259","volume":"334","author":"D He","year":"2023","unstructured":"He D, Guo T, Peng C et al (2023) Foliar application of lanthanum promotes growth and phytoremediation potential Solanum nigrum L. J Environ Manage 334:117259. https:\/\/doi.org\/10.1016\/j.jenvman.2023.117259","journal-title":"J Environ Manage"},{"key":"2252_CR19","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1080\/15226514.2017.1365344","volume":"20","author":"R-Z Huang","year":"2018","unstructured":"Huang R-Z, Jiang Y-B, Jia C-H et al (2018) Subcellular distribution and chemical forms of cadmium in Morus alba L. Int J Phytoremediation 20:448\u2013453. https:\/\/doi.org\/10.1080\/15226514.2017.1365344","journal-title":"Int J Phytoremediation"},{"key":"2252_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.172812","volume":"931","author":"D Huang","year":"2024","unstructured":"Huang D, Chen X, Yun F et al (2024) Nitric oxide alleviates programmed cell death induced by cadmium in Solanum lycopersicum seedlings through protein S-nitrosylation. Sci Total Environ 931:172812. https:\/\/doi.org\/10.1016\/j.scitotenv.2024.172812","journal-title":"Sci Total Environ"},{"key":"2252_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/agronomy14081857","volume":"14","author":"M Imran","year":"2024","unstructured":"Imran M, Hussain S, Rana MS et al (2024) Exogenously applied sodium nitroprusside alleviated cadmium toxicity in different aromatic rice cultivars by improving nitric oxide accumulation and modulating oxidative metabolism. Agronomy 14:1857. https:\/\/doi.org\/10.3390\/agronomy14081857","journal-title":"Agronomy"},{"key":"2252_CR22","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1016\/j.envpol.2010.11.029","volume":"159","author":"P Ji","year":"2011","unstructured":"Ji P, Sun T, Song Y et al (2011) Strategies for enhancing the phytoremediation of cadmium-contaminated agricultural soils by Solanum nigrum L. Environ Pollut 159:762\u2013768. https:\/\/doi.org\/10.1016\/j.envpol.2010.11.029","journal-title":"Environ Pollut"},{"key":"2252_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2021.112097","volume":"214","author":"Y Jiang","year":"2021","unstructured":"Jiang Y, Han J, Xue W et al (2021) Overexpression of SmZIP plays important roles in Cd accumulation and translocation, subcellular distribution, and chemical forms in transgenic tobacco under Cd stress. Ecotoxicol Environ Saf 214:112097. https:\/\/doi.org\/10.1016\/j.ecoenv.2021.112097","journal-title":"Ecotoxicol Environ Saf"},{"key":"2252_CR24","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1016\/j.jplph.2016.01.017","volume":"193","author":"Q Kan","year":"2016","unstructured":"Kan Q, Wu W, Yu W et al (2016) Nitrate reductase-mediated NO production enhances Cd accumulation in Panax notoginseng roots by affecting root cell wall properties. J Plant Physiol 193:64\u201370. https:\/\/doi.org\/10.1016\/j.jplph.2016.01.017","journal-title":"J Plant Physiol"},{"key":"2252_CR25","doi-asserted-by":"publisher","first-page":"786","DOI":"10.1111\/nph.20085","volume":"244","author":"Z Kolbert","year":"2024","unstructured":"Kolbert Z, Barroso JB, Boscari A et al (2024) Interorgan, intraorgan and interplant communication mediated by nitric oxide and related species. New Phytol 244:786\u2013797. https:\/\/doi.org\/10.1111\/nph.20085","journal-title":"New Phytol"},{"key":"2252_CR26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2019.121874","volume":"389","author":"X Li","year":"2020","unstructured":"Li X, Cui X, Zhang X et al (2020) Combined toxicity and detoxification of lead, cadmium and arsenic in Solanum nigrum L. J Hazard Mater 389:121874. https:\/\/doi.org\/10.1016\/j.jhazmat.2019.121874","journal-title":"J Hazard Mater"},{"key":"2252_CR27","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2023.121433","volume":"325","author":"Y Li","year":"2023","unstructured":"Li Y, Rahman SU, Qiu Z et al (2023) Toxic effects of cadmium on the physiological and biochemical attributes of plants, and phytoremediation strategies: a review. Environ Pollut 325:121433. https:\/\/doi.org\/10.1016\/j.envpol.2023.121433","journal-title":"Environ Pollut"},{"key":"2252_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2024.108401","volume":"207","author":"L Li","year":"2024","unstructured":"Li L, Wu W, Lin H et al (2024) Amino acid application inhibits root-to-shoot cadmium translocation in Chinese cabbage by modulating pectin methyl-esterification. Plant Physiol Biochem 207:108401. https:\/\/doi.org\/10.1016\/j.plaphy.2024.108401","journal-title":"Plant Physiol Biochem"},{"key":"2252_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.plaphy.2013.03.018","volume":"68","author":"J Liu","year":"2013","unstructured":"Liu J, Zhang H, Zhang Y, Chai T (2013) Silicon attenuates cadmium toxicity in Solanum nigrum L. by reducing cadmium uptake and oxidative stress. Plant Physiol Biochem 68:1\u20137. https:\/\/doi.org\/10.1016\/j.plaphy.2013.03.018","journal-title":"Plant Physiol Biochem"},{"key":"2252_CR56","doi-asserted-by":"publisher","DOI":"10.3321\/j.issn:1671-3877.2005.02.013","author":"T Ling","year":"2005","unstructured":"Ling T, Xuan W, Fan Y, et al (2005) The Effect of Exogenous Glucose, Fructose and NO Donor Sodium Nitroprusside (SNP) on Rice Seed Germination Under Salt Stress. Journal of Plant Physiology and Molecular Biology 31 (2):205-212. https:\/\/doi.org\/10.3321\/j.issn:1671-3877.2005.02.013","journal-title":"Journal of Plant Physiology and Molecular Biology"},{"key":"2252_CR30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2020.122679","volume":"395","author":"X Liu","year":"2020","unstructured":"Liu X, Yin L, Deng X et al (2020) Combined application of silicon and nitric oxide jointly alleviated cadmium accumulation and toxicity in maize. J Hazard Mater 395:122679. https:\/\/doi.org\/10.1016\/j.jhazmat.2020.122679","journal-title":"J Hazard Mater"},{"key":"2252_CR31","doi-asserted-by":"publisher","first-page":"3823","DOI":"10.1007\/s42729-023-01302-7","volume":"23","author":"W Liu","year":"2023","unstructured":"Liu W, Yu T, Cao H et al (2023a) Effects of EDTA and organic acids on physiological processes, gene expression levels, and cadmium accumulation in Solanum nigrum under cadmium stress. J Soil Sci Plant Nutr 23:3823\u20133833. https:\/\/doi.org\/10.1007\/s42729-023-01302-7","journal-title":"J Soil Sci Plant Nutr"},{"key":"2252_CR32","doi-asserted-by":"publisher","DOI":"10.3390\/plants12071494","volume":"12","author":"X Liu","year":"2023","unstructured":"Liu X, Gong D, Ke Q et al (2023b) Meta-analysis of the effect of nitric oxide application on heavy metal stress tolerance in plants. Plants 12:1494. https:\/\/doi.org\/10.3390\/plants12071494","journal-title":"Plants"},{"key":"2252_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2024.117588","volume":"290","author":"M Liu","year":"2025","unstructured":"Liu M, Feng Y, Wang M et al (2025a) Sedum alfredii Hance: a cadmium and zinc hyperaccumulating plant. Ecotoxicol Environ Saf 290:117588. https:\/\/doi.org\/10.1016\/j.ecoenv.2024.117588","journal-title":"Ecotoxicol Environ Saf"},{"key":"2252_CR34","doi-asserted-by":"publisher","DOI":"10.1016\/j.xplc.2025.101459","volume":"6","author":"Z Liu","year":"2025","unstructured":"Liu Z, Zhao Y, Mao L et al (2025b) A bHLH7\u2013PDF2 module mediates transcriptional regulation to repress seed oil accumulation in Arabidopsis thaliana. Plant Commun 6:101459. https:\/\/doi.org\/10.1016\/j.xplc.2025.101459","journal-title":"Plant Commun"},{"key":"2252_CR35","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1111\/pce.14007","volume":"44","author":"C L\u00f3pez\u2010Hidalgo","year":"2021","unstructured":"L\u00f3pez\u2010Hidalgo C, Meij\u00f3n M, Lamelas L, Valledor L (2021) The rainbow protocol: a sequential method for quantifying pigments, sugars, free amino acids, phenolics, flavonoids and MDA from a small amount of sample. Plant Cell Environ 44:1977\u20131986. https:\/\/doi.org\/10.1111\/pce.14007","journal-title":"Plant Cell Environ"},{"key":"2252_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.envpol.2025.125664","volume":"367","author":"Y Luo","year":"2025","unstructured":"Luo Y, Huang X, Sha A et al (2025) Analysis of growth physiological changes and metabolome of highland barley seedlings under cadmium (II) stress. Environ Pollut 367:125664. https:\/\/doi.org\/10.1016\/j.envpol.2025.125664","journal-title":"Environ Pollut"},{"key":"2252_CR37","doi-asserted-by":"publisher","DOI":"10.3390\/plants12112123","volume":"12","author":"D Maslennikova","year":"2023","unstructured":"Maslennikova D, Ivanov S, Petrova S et al (2023) Components of the phenylpropanoid pathway in the implementation of the protective effect of sodium nitroprusside on wheat under salinity. Plants (Basel) 12:2123. https:\/\/doi.org\/10.3390\/plants12112123","journal-title":"Plants (Basel)"},{"key":"2252_CR38","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23136901","volume":"23","author":"Y Meng","year":"2022","unstructured":"Meng Y, Jing H, Huang J et al (2022) The role of nitric oxide signaling in plant responses to cadmium stress. Int J Mol Sci 23:6901. https:\/\/doi.org\/10.3390\/ijms23136901","journal-title":"Int J Mol Sci"},{"key":"2252_CR39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0327497","volume":"20","author":"Z Meng","year":"2025","unstructured":"Meng Z, Zhang W, Guo Z et al (2025) Metabolomics analysis of mechanism of improving quality of Schisandrae chinensis fructus by NO combining with high-temperature stress. PLoS ONE 20:e0327497. https:\/\/doi.org\/10.1371\/journal.pone.0327497","journal-title":"PLoS ONE"},{"key":"2252_CR40","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s10534-012-9597-8","volume":"26","author":"P Mishra","year":"2013","unstructured":"Mishra P, Dubey RS (2013) Excess nickel modulates activities of carbohydrate metabolizing enzymes and induces accumulation of sugars by upregulating acid invertase and sucrose synthase in rice seedlings. Biometals 26:97\u2013111. https:\/\/doi.org\/10.1007\/s10534-012-9597-8","journal-title":"Biometals"},{"key":"2252_CR41","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S0013-9351(02)00012-9","volume":"91","author":"Z Prokop","year":"2003","unstructured":"Prokop Z, Cupr P, Zlevorova-Zlamalikova V et al (2003) Mobility, bioavailability, and toxic effects of cadmium in soil samples. Environ Res 91:119\u2013126. https:\/\/doi.org\/10.1016\/S0013-9351(02)00012-9","journal-title":"Environ Res"},{"key":"2252_CR42","doi-asserted-by":"publisher","DOI":"10.1186\/s12870-024-05551-1","volume":"24","author":"T Ran","year":"2024","unstructured":"Ran T, Cao G, Xiao L et al (2024) Effects of cadmium stress on the growth and physiological characteristics of sweet potato. BMC Plant Biol 24:850. https:\/\/doi.org\/10.1186\/s12870-024-05551-1","journal-title":"BMC Plant Biol"},{"key":"2252_CR43","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.172695","volume":"930","author":"X Shi","year":"2024","unstructured":"Shi X, Du J, Wang X et al (2024) NtGCN2 confers cadmium tolerance in Nicotiana tabacum L. by regulating cadmium uptake, efflux, and subcellular distribution. Sci Total Environ 930:172695. https:\/\/doi.org\/10.1016\/j.scitotenv.2024.172695","journal-title":"Sci Total Environ"},{"key":"2252_CR44","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.niox.2024.11.002","volume":"154","author":"K Song","year":"2025","unstructured":"Song K, Li H, Yang K et al (2025) Exogenous sodium nitroprusside exhibits multiple positive roles in alleviating cadmium toxicity in tobacco (Nicotiana tabacum L.). Nitric Oxide 154:8\u201318. https:\/\/doi.org\/10.1016\/j.niox.2024.11.002","journal-title":"Nitric Oxide"},{"key":"2252_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.plaphy.2025.110016","volume":"225","author":"Y Teng","year":"2025","unstructured":"Teng Y, Xiao Y, Sun H et al (2025) Cadmium-induced mitochondrial dysfunction and oxidative damage in leaves of Solanum nigrum L. Plant Physiol Biochem 225:110016. https:\/\/doi.org\/10.1016\/j.plaphy.2025.110016","journal-title":"Plant Physiol Biochem"},{"key":"2252_CR46","doi-asserted-by":"publisher","first-page":"3489","DOI":"10.1007\/s11356-014-3581-5","volume":"22","author":"D Wang","year":"2015","unstructured":"Wang D, Liu Y, Tan X et al (2015) Effect of exogenous nitric oxide on antioxidative system and S-nitrosylation in leaves of Boehmeria nivea (L.) Gaud under cadmium stress. Environ Sci Pollut Res 22:3489\u20133497. https:\/\/doi.org\/10.1007\/s11356-014-3581-5","journal-title":"Environ Sci Pollut Res"},{"key":"2252_CR47","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2025.112664","volume":"359","author":"M Wang","year":"2025","unstructured":"Wang M, Haris M, Zhang C et al (2025) Cell wall polysaccharides response to cadmium stress and transcriptome analysis in tomato (Solanum lycopersicum). Plant Sci 359:112664. https:\/\/doi.org\/10.1016\/j.plantsci.2025.112664","journal-title":"Plant Sci"},{"key":"2252_CR48","doi-asserted-by":"publisher","DOI":"10.1016\/j.plantsci.2023.111754","volume":"334","author":"KI Wani","year":"2023","unstructured":"Wani KI, Naeem M, Khan MMA, Aftab T (2023) Nitric oxide induces antioxidant machinery, PSII functioning and artemisinin biosynthesis in Artemisia annua under cadmium stress. Plant Sci 334:111754. https:\/\/doi.org\/10.1016\/j.plantsci.2023.111754","journal-title":"Plant Sci"},{"key":"2252_CR49","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.scitotenv.2006.06.014","volume":"369","author":"S Wei","year":"2006","unstructured":"Wei S, Zhou Q, Koval PV (2006) Flowering stage characteristics of cadmium hyperaccumulator Solanum nigrum L. and their significance to phytoremediation. Sci Total Environ 369:441\u2013446. https:\/\/doi.org\/10.1016\/j.scitotenv.2006.06.014","journal-title":"Sci Total Environ"},{"key":"2252_CR50","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1007\/s11368-013-0687-1","volume":"13","author":"S Wei","year":"2013","unstructured":"Wei S, Wang S, Li Y, Zhu J (2013) Root system responses of hyperaccumulator Solanum nigrum L. to Cd. J Soils Sediments 13:1069\u20131074. https:\/\/doi.org\/10.1007\/s11368-013-0687-1","journal-title":"J Soils Sediments"},{"key":"2252_CR51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.131214","volume":"452","author":"Z Wei","year":"2023","unstructured":"Wei Z, Zhongbing C, Xiuqin Y et al (2023) Integrated transcriptomics and metabolomics reveal key metabolic pathway responses in Pistia stratiotes under Cd stress. J Hazard Mater 452:131214. https:\/\/doi.org\/10.1016\/j.jhazmat.2023.131214","journal-title":"J Hazard Mater"},{"key":"2252_CR52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2022.113404","volume":"234","author":"H Yang","year":"2022","unstructured":"Yang H, Yu H, Wu Y et al (2022) Nitric oxide amplifies cadmium binding in root cell wall of a high cadmium-accumulating rice (Oryza sativa L.) line by promoting hemicellulose synthesis and pectin demethylesterification. Ecotoxicol Environ Saf 234:113404. https:\/\/doi.org\/10.1016\/j.ecoenv.2022.113404","journal-title":"Ecotoxicol Environ Saf"},{"key":"2252_CR53","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1016\/j.cj.2022.09.013","volume":"11","author":"W Yang","year":"2023","unstructured":"Yang W, Chen L, Ma Y et al (2023) OsNRAMP2 facilitates Cd efflux from vacuoles and contributes to the difference in grain Cd accumulation between japonica and indica rice. Crop J 11:417\u2013426. https:\/\/doi.org\/10.1016\/j.cj.2022.09.013","journal-title":"Crop J"},{"key":"2252_CR54","doi-asserted-by":"publisher","unstructured":"Yu Z, Huang X, Xiang J, et al (2025) PSI-mediated NADPH production and enzyme regulation are critical for carbon assimilation in pepper seedlings under cadmium stress. Hortic Plant J S246801412500055X. https:\/\/doi.org\/10.1016\/j.hpj.2025.01.005","DOI":"10.1016\/j.hpj.2025.01.005"},{"key":"2252_CR55","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1016\/j.envexpbot.2017.06.011","volume":"141","author":"S Zafari","year":"2017","unstructured":"Zafari S, Sharifi M, Chashmi NA (2017) Nitric oxide production shifts metabolic pathways toward lignification to alleviate Pb stress in Prosopis farcta. Environ Exp Bot 141:41\u201349. https:\/\/doi.org\/10.1016\/j.envexpbot.2017.06.011","journal-title":"Environ Exp Bot"},{"key":"2252_CR57","doi-asserted-by":"publisher","unstructured":"Zheng M-M, Feng D, Liu H-J, Yang G-L (2023) Subcellular distribution, chemical forms of cadmium and rhizosphere microbial community in the process of cadmium hyperaccumulation in duckweed. Science of The Total Environment 859:160389. https:\/\/doi.org\/10.1016\/j.scitotenv.2022.160389","DOI":"10.1016\/j.scitotenv.2022.160389"}],"container-title":["Protoplasma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00709-026-02252-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00709-026-02252-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00709-026-02252-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T18:11:16Z","timestamp":1785521476000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00709-026-02252-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,28]]},"references-count":57,"alternative-id":["2252"],"URL":"https:\/\/doi.org\/10.1007\/s00709-026-02252-4","relation":{},"ISSN":["0033-183X","1615-6102"],"issn-type":[{"value":"0033-183X","type":"print"},{"value":"1615-6102","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,28]]},"assertion":[{"value":"1 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}