{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T05:40:45Z","timestamp":1790487645769,"version":"4.1.0"},"reference-count":67,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2006,10,10]],"date-time":"2006-10-10T00:00:00Z","timestamp":1160438400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amino Acids"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1007\/s00726-006-0409-8","type":"journal-article","created":{"date-parts":[[2006,10,7]],"date-time":"2006-10-07T11:34:24Z","timestamp":1160220864000},"page":"213-224","source":"Crossref","is-referenced-by-count":230,"title":["Free amino acid and dipeptide changes in the body fluids from Alzheimer\u2019s disease subjects"],"prefix":"10.1007","volume":"32","author":[{"given":"A. N.","family":"Fonteh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. J.","family":"Harrington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. G.","family":"Harrington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,10,10]]},"reference":[{"key":"409_CR1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0149-7634(05)80046-6","volume":"16","author":"C Advokat","year":"1992","journal-title":"Neurosci Biobehav Rev"},{"key":"409_CR2","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S0140-6736(79)91003-1","volume":"1","author":"Y Agid","year":"1979","journal-title":"Lancet"},{"key":"409_CR3","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0047-6374(00)00183-4","volume":"120","author":"P Barbanti","year":"2000","journal-title":"Mech Ageing Dev"},{"key":"409_CR4","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0165-5728(96)00127-0","volume":"71","author":"P Barili","year":"1996","journal-title":"J Neuroimmunol"},{"key":"409_CR5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1471-4159.1958.tb12623.x","volume":"3","author":"S Berl","year":"1958","journal-title":"J Neurochem"},{"key":"409_CR6","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1023\/A:1020271013277","volume":"19","author":"AA Boldyrev","year":"1999","journal-title":"Biosci Rep"},{"key":"409_CR7","first-page":"281","volume":"16","author":"P Bolme","year":"1977","journal-title":"Adv Biochem Psychopharmacol"},{"key":"409_CR8","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0301-0082(99)00010-6","volume":"59","author":"L Bonfanti","year":"1999","journal-title":"Prog Neurobiol"},{"key":"409_CR9","first-page":"15","volume":"129","author":"D Bowen","year":"1990","journal-title":"Acta Neurol Scand [Suppl]"},{"key":"409_CR10","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1097\/00001756-199909290-00006","volume":"10","author":"B Caronti","year":"1999","journal-title":"Neuroreport"},{"key":"409_CR11","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0168-9525(01)02285-5","volume":"17","author":"PF Chapman","year":"2001","journal-title":"Trends Genet"},{"key":"409_CR12","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S0031-6989(80)80108-1","volume":"12","author":"GU Corsini","year":"1980","journal-title":"Pharmacol Res Commun"},{"key":"409_CR13","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1212\/WNL.46.6.1715","volume":"46","author":"JG Csernansky","year":"1996","journal-title":"Neurology"},{"key":"409_CR14","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1176\/ps.50.9.1173","volume":"50","author":"JL Cummings","year":"1999","journal-title":"Psychiatr Serv"},{"key":"409_CR15","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1212\/WNL.53.5.899","volume":"53","author":"JL Cummings","year":"1999","journal-title":"Neurology"},{"key":"409_CR16","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1212\/WNL.51.1_Suppl_1.S2","volume":"51","author":"JL Cummings","year":"1998","journal-title":"Neurology"},{"key":"409_CR17","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1046\/j.1468-2982.1991.1104197.x","volume":"11","author":"G D\u2019Andrea","year":"1991","journal-title":"Cephalalgia"},{"key":"409_CR18","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1006\/exnr.1996.0034","volume":"137","author":"I Date","year":"1996","journal-title":"Exp Neurol"},{"key":"409_CR19","doi-asserted-by":"crossref","first-page":"M173","DOI":"10.1093\/gerona\/57.3.M173","volume":"57","author":"PM Doraiswamy","year":"2002","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"409_CR20","doi-asserted-by":"crossref","first-page":"6386","DOI":"10.1021\/bi00240a006","volume":"30","author":"PF Fitzpatrick","year":"1991","journal-title":"Biochemistry"},{"key":"409_CR21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.1984.tb09689.x","volume":"42","author":"F Fonnum","year":"1984","journal-title":"J Neurochem"},{"key":"409_CR22","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/s00726-006-0370-6","volume":"32","author":"AN Fonteh","year":"2007","journal-title":"Amino Acids"},{"key":"409_CR23","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1046\/j.1468-2982.2003.00552.x","volume":"23","author":"V Gallai","year":"2003","journal-title":"Cephalalgia"},{"key":"409_CR24","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1016\/0306-3623(95)00009-P","volume":"26","author":"GB Glavin","year":"1995","journal-title":"Gen Pharmacol"},{"issue":"[Suppl 1]","key":"409_CR25","doi-asserted-by":"crossref","first-page":"S93","DOI":"10.1291\/hypres.18.SupplementI_S93","volume":"18","author":"DS Goldstein","year":"1995","journal-title":"Hypertens Res"},{"key":"409_CR26","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0021-9258(18)64830-6","volume":"226","author":"BS Gould","year":"1957","journal-title":"J Biol Chem"},{"key":"409_CR27","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0197-4580(89)90143-7","volume":"10","author":"JT Greenamyre","year":"1989","journal-title":"Neurobiol Aging"},{"key":"409_CR28","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/j.1749-6632.2000.tb06192.x","volume":"899","author":"E Grunblatt","year":"2000","journal-title":"Ann NY Acad Sci"},{"key":"409_CR29","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1016\/S0197-4580(02)00006-4","volume":"23","author":"AR Hipkiss","year":"2002","journal-title":"Neurobiol Aging"},{"key":"409_CR30","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0378-4347(98)00136-4","volume":"717","author":"P Husek","year":"1998","journal-title":"J Chromatogr B Biomed Sci Appl"},{"key":"409_CR31","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1212\/WNL.56.9.1143","volume":"56","author":"DS Knopman","year":"2001","journal-title":"Neurology"},{"key":"409_CR32","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1073\/pnas.85.9.3175","volume":"85","author":"R Kohen","year":"1988","journal-title":"Proc Natl Acad Sci USA"},{"key":"409_CR33","doi-asserted-by":"crossref","first-page":"25S","DOI":"10.1093\/ajh\/3.6.25S","volume":"3","author":"JD Kohli","year":"1990","journal-title":"Am J Hypertens"},{"key":"409_CR34","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1161\/01.HYP.17.5.700","volume":"17","author":"JD Kohli","year":"1991","journal-title":"Hypertension"},{"key":"409_CR35","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/sj.jhh.1000870","volume":"13","author":"O Kuchel","year":"1999","journal-title":"J Hum Hypertens"},{"key":"409_CR36","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1111\/j.1471-4159.1982.tb07925.x","volume":"38","author":"Z Lackovic","year":"1982","journal-title":"J Neurochem"},{"key":"409_CR37","doi-asserted-by":"crossref","first-page":"C1101","DOI":"10.1152\/ajpcell.1998.274.4.C1101","volume":"274","author":"WJ Lee","year":"1998","journal-title":"Am J Physiol"},{"key":"409_CR38","doi-asserted-by":"crossref","first-page":"3293","DOI":"10.1097\/00001756-200110290-00029","volume":"12","author":"Z Liu","year":"2001","journal-title":"Neuroreport"},{"key":"409_CR39","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0165-1781(92)90037-4","volume":"42","author":"D Marazziti","year":"1992","journal-title":"Psychiatry Res"},{"key":"409_CR40","first-page":"824","volume":"65","author":"SD Marchis","year":"2000","journal-title":"Biochemistry (Mosc.)"},{"key":"409_CR41","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1750-3639.1999.tb00215.x","volume":"9","author":"WR Markesbery","year":"1999","journal-title":"Brain Pathol"},{"key":"409_CR42","first-page":"257","volume":"84","author":"A Mayerhofer","year":"1999","journal-title":"J Clin Endocrinol Metab"},{"key":"409_CR43","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1212\/WNL.34.7.939","volume":"34","author":"G McKhann","year":"1984","journal-title":"Neurology"},{"key":"409_CR44","first-page":"19","volume":"22","author":"M Memo","year":"1986","journal-title":"J Neural Transm [Suppl]"},{"key":"409_CR45","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1002\/(SICI)1097-0258(20000615\/30)19:11\/12<1607::AID-SIM449>3.0.CO;2-O","volume":"19","author":"MS Mendiondo","year":"2000","journal-title":"Stat Med"},{"key":"409_CR46","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s007020050057","volume":"105","author":"JA Molina","year":"1998","journal-title":"J Neural Transm"},{"key":"409_CR47","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1056\/NEJMra010253","volume":"345","author":"MB Murphy","year":"2001","journal-title":"N Engl J Med"},{"key":"409_CR48","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1038\/nrn916","volume":"3","author":"M Nedergaard","year":"2002","journal-title":"Nat Rev Neurosci"},{"key":"409_CR49","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/ana.410210403","volume":"21","author":"TL Perry","year":"1987","journal-title":"Ann Neurol"},{"key":"409_CR50","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1176\/ajp.149.2.251","volume":"149","author":"N Pomara","year":"1992","journal-title":"Am J Psychiatry"},{"key":"409_CR51","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0304-3940(98)00058-5","volume":"242","author":"JE Preston","year":"1998","journal-title":"Neurosci Lett"},{"key":"409_CR52","first-page":"27","volume":"1","author":"R Sandbrink","year":"1996","journal-title":"Mol Psychiatry"},{"key":"409_CR53","doi-asserted-by":"crossref","first-page":"219A","DOI":"10.1111\/j.1530-0277.1996.tb01780.x","volume":"20","author":"P Schofield","year":"1996","journal-title":"Alcohol Clin Exp Res"},{"key":"409_CR54","first-page":"39","volume":"28","author":"AN Singh","year":"2003","journal-title":"J Psychiatry Neurosci"},{"key":"409_CR55","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/S0140-6736(75)90256-1","volume":"2","author":"SR Snider","year":"1975","journal-title":"Lancet"},{"key":"409_CR56","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/0304-3940(95)12256-7","volume":"203","author":"D Storga","year":"1996","journal-title":"Neurosci Lett"},{"key":"409_CR57","first-page":"862","volume":"65","author":"HJ Stuerenburg","year":"2000","journal-title":"Biochemistry (Mosc.)"},{"key":"409_CR58","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1023\/A:1023855428130","volume":"135","author":"SL Stvolinskii","year":"2003","journal-title":"Bull Exp Biol Med"},{"key":"409_CR59","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0006-8993(75)90960-9","volume":"88","author":"WH Vogel","year":"1975","journal-title":"Brain Res"},{"key":"409_CR60","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1021\/cr020634j","volume":"104","author":"FA Walker","year":"2004","journal-title":"Chem Rev"},{"key":"409_CR61","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0730-725X(02)00472-1","volume":"20","author":"D Wang","year":"2002","journal-title":"Magn Reson Imaging"},{"key":"409_CR62","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0361-9230(99)00102-1","volume":"50","author":"RJ Weinberg","year":"1999","journal-title":"Brain Res Bull"},{"key":"409_CR63","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1017\/S1041610297004298","volume":"9","author":"G Weyer","year":"1997","journal-title":"Int Psychogeriatr"},{"key":"409_CR64","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/0163-1047(93)90998-W","volume":"59","author":"NM White","year":"1993","journal-title":"Behav Neural Biol"},{"key":"409_CR65","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1253\/jcj.49.1028","volume":"49","author":"S Yoneda","year":"1985","journal-title":"Jpn Circ J"},{"key":"409_CR66","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1046\/j.1471-4159.2000.0740970.x","volume":"74","author":"J Zhang","year":"2000","journal-title":"J Neurochem"},{"key":"409_CR67","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/abio.2000.4676","volume":"284","author":"SS Zuo","year":"2000","journal-title":"Anal Biochem"}],"container-title":["Amino Acids"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-006-0409-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00726-006-0409-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-006-0409-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T23:23:07Z","timestamp":1627860187000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00726-006-0409-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,10,10]]},"references-count":67,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["409"],"URL":"https:\/\/doi.org\/10.1007\/s00726-006-0409-8","relation":{},"ISSN":["0939-4451","1438-2199"],"issn-type":[{"value":"0939-4451","type":"print"},{"value":"1438-2199","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,10,10]]}}}