{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T11:20:52Z","timestamp":1725880852443},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2014,3,16]],"date-time":"2014-03-16T00:00:00Z","timestamp":1394928000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Amino Acids"],"published-print":{"date-parts":[[2014,6]]},"DOI":"10.1007\/s00726-014-1712-4","type":"journal-article","created":{"date-parts":[[2014,3,18]],"date-time":"2014-03-18T03:56:54Z","timestamp":1395115014000},"page":"1471-1480","source":"Crossref","is-referenced-by-count":13,"title":["Bleomycin hydrolase and hyperhomocysteinemia modulate the expression of mouse proteins involved in liver homeostasis"],"prefix":"10.1007","volume":"46","author":[{"given":"Joanna","family":"Suszy\u0144ska-Zajczyk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Wr\u00f3blewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olga","family":"Utyro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"\u0141uczak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0141ukasz","family":"Marczak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hieronim","family":"Jakubowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,3,16]]},"reference":[{"key":"1712_CR1","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1007\/s00726-011-1207-5","volume":"43","author":"K Borowczyk","year":"2012","unstructured":"Borowczyk K, Tisonczyk J, Jakubowski H (2012) Metabolism and neurotoxicity of homocysteine thiolactone in mice: protective role of bleomycin hydrolase. Amino Acids 43:1339\u20131348","journal-title":"Amino Acids"},{"key":"1712_CR2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.18388\/abp.2004_3580","volume":"51","author":"JT Brosnan","year":"2004","unstructured":"Brosnan JT, Jacobs RL, Stead LM, Brosnan ME (2004) Methylation demand: a key determinant of homocysteine metabolism. Acta Biochim Pol 51:405\u2013413","journal-title":"Acta Biochim Pol"},{"key":"1712_CR3","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1096\/fj.06-7435com","volume":"21","author":"G Chwatko","year":"2007","unstructured":"Chwatko G, Boers GH, Strauss KA, Shih DM, Jakubowski H (2007) Mutations in methylenetetrahydrofolate reductase or cystathionine beta-synthase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice. Faseb J 21:1707\u20131713","journal-title":"Faseb J"},{"key":"1712_CR4","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S1096-7192(03)00069-6","volume":"79","author":"AM Das","year":"2003","unstructured":"Das AM (2003) Regulation of the mitochondrial ATP-synthase in health and disease. Mol Genet Metab 79:71\u201382","journal-title":"Mol Genet Metab"},{"key":"1712_CR5","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.neulet.2009.11.014","volume":"468","author":"ML Bonis De","year":"2010","unstructured":"De Bonis ML, Tessitore A, Pellecchia MT, Longo K, Salvatore A, Russo A, Ingrosso D, Zappia V, Barone P, Galletti P, Tedeschi G (2010) Impaired transmethylation potential in Parkinson\u2019s disease patients treated with L-Dopa. Neurosci Lett 468:287\u2013291","journal-title":"Neurosci Lett"},{"key":"1712_CR6","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1074\/mcp.M900406-MCP200","volume":"9","author":"PM DiBello","year":"2010","unstructured":"DiBello PM, Dayal S, Kaveti S, Zhang D, Kinter M, Lentz SR, Jacobsen DW (2010) The nutrigenetics of hyperhomocysteinemia: quantitative proteomics reveals differences in the methionine cycle enzymes of gene-induced versus diet-induced hyperhomocysteinemia. Mol Cell Proteomics MCP 9:471\u2013485","journal-title":"Mol Cell Proteomics MCP"},{"key":"1712_CR7","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3389\/fgene.2012.00250","volume":"3","author":"MG Distler","year":"2012","unstructured":"Distler MG, Palmer AA (2012) Role of Glyoxalase 1 (Glo1) and methylglyoxal (MG) in behavior: recent advances and mechanistic insights. Front Genet 3:250","journal-title":"Front Genet"},{"key":"1712_CR8","doi-asserted-by":"crossref","unstructured":"Fleming TH, Theilen TM, Masania J, Wunderle M, Karimi J, Vittas S, Bernauer R, Bierhaus A, Rabbani N, Thornalley PJ, Kroll J, Tyedmers J, Nawrotzki R, Herzig S, Brownlee M, Nawroth PP (2013) Aging-dependent reduction in glyoxalase 1 delays wound healing. Gerontology 59:427\u2013437","DOI":"10.1159\/000351628"},{"key":"1712_CR9","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1007\/s00726-010-0627-y","volume":"39","author":"R Glowacki","year":"2010","unstructured":"Glowacki R, Bald E, Jakubowski H (2010) Identification and origin of Nepsilon\u2013homocysteinyl\u2013lysine isopeptide in humans and mice. Amino Acids 39:1563\u20131569","journal-title":"Amino Acids"},{"key":"1712_CR10","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.atherosclerosis.2010.11.031","volume":"214","author":"RM Gueant-Rodriguez","year":"2011","unstructured":"Gueant-Rodriguez RM, Spada R, Moreno-Garcia M, Anello G, Bosco P, Lagrost L, Romano A, Elia M, Gueant JL (2011) Homocysteine is a determinant of ApoA-I and both are associated with ankle brachial index, in an ambulatory elderly population. Atherosclerosis 214:480\u2013485","journal-title":"Atherosclerosis"},{"key":"1712_CR11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.jhep.2006.07.028","volume":"46","author":"J Hamelet","year":"2007","unstructured":"Hamelet J, Demuth K, Paul JL, Delabar JM, Janel N (2007) Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in mice. J Hepatol 46:151\u2013159","journal-title":"J Hepatol"},{"key":"1712_CR12","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.nut.2004.03.022","volume":"21","author":"S Hirsch","year":"2005","unstructured":"Hirsch S, Poniachick J, Avendano M, Csendes A, Burdiles P, Smok G, Diaz JC, de la Maza MP (2005) Serum folate and homocysteine levels in obese females with non-alcoholic fatty liver. Nutrition (Burbank, Los Angeles County, Calif) 21:137\u2013141","journal-title":"Nutrition (Burbank, Los Angeles County, Calif)"},{"key":"1712_CR13","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1172\/JCI10588","volume":"107","author":"MA Hofmann","year":"2001","unstructured":"Hofmann MA, Lalla E, Lu Y, Gleason MR, Wolf BM, Tanji N, Ferran LJ Jr, Kohl B, Rao V, Kisiel W, Stern DM, Schmidt AM (2001) Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model. J Clin Invest 107:675\u2013683","journal-title":"J Clin Invest"},{"key":"1712_CR14","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/ane.12106","volume":"128","author":"XW Hu","year":"2013","unstructured":"Hu XW, Qin SM, Li D, Hu LF, Liu CF (2013) Elevated homocysteine levels in levodopa-treated idiopathic Parkinson\u2019s disease: a meta-analysis. Acta Neurol Scand 128:73\u201382","journal-title":"Acta Neurol Scand"},{"key":"1712_CR15","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1258\/acb.2010.010035","volume":"47","author":"N Ishimine","year":"2010","unstructured":"Ishimine N, Usami Y, Nogi S, Sumida T, Kurihara Y, Matsuda K, Nakamura K, Yamauchi K, Okumura N, Tozuka M (2010) Identification of N-homocysteinylated apolipoprotein AI in normal human serum. Ann Clin Biochem 47:453\u2013459","journal-title":"Ann Clin Biochem"},{"key":"1712_CR16","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1016\/S0021-9258(19)67504-6","volume":"272","author":"H Jakubowski","year":"1997","unstructured":"Jakubowski H (1997) Metabolism of homocysteine thiolactone in human cell cultures. Possible mechanism for pathological consequences of elevated homocysteine levels. J Biol Chem 272:1935\u20131942","journal-title":"J Biol Chem"},{"key":"1712_CR17","doi-asserted-by":"crossref","first-page":"30425","DOI":"10.1074\/jbc.C200267200","volume":"277","author":"H Jakubowski","year":"2002","unstructured":"Jakubowski H (2002) Homocysteine is a protein amino acid in humans. Implications for homocysteine-linked disease. J Biol Chem 277:30425\u201330428","journal-title":"J Biol Chem"},{"key":"1712_CR18","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.ab.2008.05.049","volume":"380","author":"H Jakubowski","year":"2008","unstructured":"Jakubowski H (2008) New method for the determination of protein N-linked homocysteine. Anal Biochem 380:257\u2013261","journal-title":"Anal Biochem"},{"key":"1712_CR19","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-7091-1410-0","volume-title":"Homocysteine in protein structure\/function and human disease\u2014chemical biology of homocysteine-containing proteins","author":"H Jakubowski","year":"2013","unstructured":"Jakubowski H (2013) Homocysteine in protein structure\/function and human disease\u2014chemical biology of homocysteine-containing proteins. Springer, Wien"},{"key":"1712_CR20","doi-asserted-by":"crossref","first-page":"4071","DOI":"10.1096\/fj.08-112086","volume":"22","author":"H Jakubowski","year":"2008","unstructured":"Jakubowski H, Boers GH, Strauss KA (2008) Mutations in cystathionine {beta}-synthase or methylenetetrahydrofolate reductase gene increase N-homocysteinylated protein levels in humans. FASEB J 22:4071\u20134076","journal-title":"FASEB J"},{"key":"1712_CR21","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1096\/fj.08-127548","volume":"23","author":"H Jakubowski","year":"2009","unstructured":"Jakubowski H, Perla-Kajan J, Finnell RH, Cabrera RM, Wang H, Gupta S, Kruger WD, Kraus JP, Shih DM (2009) Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. Faseb J 23:1721\u20131727","journal-title":"Faseb J"},{"key":"1712_CR22","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/jb\/mvm005","volume":"141","author":"Y Kamata","year":"2007","unstructured":"Kamata Y, Itoh Y, Kajiya A, Karasawa S, Sakatani C, Takekoshi S, Osamura RY, Takeda A (2007) Quantification of neutral cysteine protease bleomycin hydrolase and its localization in rat tissues. J Biochem 141:69\u201376","journal-title":"J Biochem"},{"key":"1712_CR23","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1055\/s-2007-991513","volume":"27","author":"N Kaplowitz","year":"2007","unstructured":"Kaplowitz N, Than TA, Shinohara M, Ji C (2007) Endoplasmic reticulum stress and liver injury. Semin Liver Dis 27:367\u2013377","journal-title":"Semin Liver Dis"},{"key":"1712_CR24","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1161\/01.RES.0000242559.42077.22","volume":"99","author":"D Liao","year":"2006","unstructured":"Liao D, Tan H, Hui R, Li Z, Jiang X, Gaubatz J, Yang F, Durante W, Chan L, Schafer AI, Pownall HJ, Yang X, Wang H (2006) Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A\u2013I protein synthesis and enhancing HDL cholesterol clearance. Circ Res 99:598\u2013606","journal-title":"Circ Res"},{"key":"1712_CR25","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1477-5956-9-25","volume":"9","author":"M Luczak","year":"2011","unstructured":"Luczak M, Formanowicz D, Pawliczak E, Wanic-Kossowska M, Wykretowicz A, Figlerowicz M (2011) Chronic kidney disease-related atherosclerosis\u2014proteomic studies of blood plasma. Proteome Sci 9:25","journal-title":"Proteome Sci"},{"key":"1712_CR26","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1161\/01.RES.0000204825.66410.0b","volume":"98","author":"LG Mikael","year":"2006","unstructured":"Mikael LG, Genest J Jr, Rozen R (2006) Elevated homocysteine reduces apolipoprotein A-I expression in hyperhomocysteinemic mice and in males with coronary artery disease. Circ Res 98:564\u2013571","journal-title":"Circ Res"},{"key":"1712_CR27","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/j.neuroscience.2007.02.027","volume":"146","author":"SE Montoya","year":"2007","unstructured":"Montoya SE, Thiels E, Card JP, Lazo JS (2007) Astrogliosis and behavioral changes in mice lacking the neutral cysteine protease bleomycin hydrolase. Neuroscience 146:890\u2013900","journal-title":"Neuroscience"},{"key":"1712_CR28","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/0026-0495(80)90192-4","volume":"29","author":"SH Mudd","year":"1980","unstructured":"Mudd SH, Ebert MH, Scriver CR (1980) Labile methyl group balances in the human: the role of sarcosine. Metabolism 29:707\u2013720","journal-title":"Metabolism"},{"key":"1712_CR29","unstructured":"Mudd SH, Levy HL, Kraus JP (2001) Disorders of transsulfuration. In: Scriver CR, Beaudet AL, Sly WS, et al (eds) The metabolic and molecular bases of inherited disease, vol 2. Mc Graw-Hill, New York, pp 2007\u20132056"},{"key":"1712_CR30","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/0006-291X(87)90929-6","volume":"148","author":"T Ogawa","year":"1987","unstructured":"Ogawa T, Kimoto M, Sasaoka K (1987) Occurrence of a new enzyme catalyzing the direct conversion of NG, NG-dimethyl-l-arginine to l-citrulline in rats. Biochem Biophys Res Commun 148:671\u2013677","journal-title":"Biochem Biophys Res Commun"},{"key":"1712_CR31","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/s007260170037","volume":"20","author":"M Rauh","year":"2001","unstructured":"Rauh M, Verwied S, Knerr I, Dorr HG, Sonnichsen A, Koletzko B (2001) Homocysteine concentrations in a German cohort of 500 individuals: reference ranges and determinants of plasma levels in healthy children and their parents. Amino Acids 20:409\u2013418","journal-title":"Amino Acids"},{"key":"1712_CR32","doi-asserted-by":"crossref","first-page":"4680","DOI":"10.1073\/pnas.96.8.4680","volume":"96","author":"DR Schwartz","year":"1999","unstructured":"Schwartz DR, Homanics GE, Hoyt DG, Klein E, Abernethy J, Lazo JS (1999) The neutral cysteine protease bleomycin hydrolase is essential for epidermal integrity and bleomycin resistance. Proc Natl Acad Sci USA 96:4680\u20134685","journal-title":"Proc Natl Acad Sci USA"},{"key":"1712_CR33","first-page":"698","volume":"37","author":"VA Spitsyn","year":"2001","unstructured":"Spitsyn VA, Nafikova A, Spitsyna N, Afanas\u2019eva IS (2001) Genetic predisposition to development of toxic liver cirrhosis caused by alcohol. Genetika 37:698\u2013707","journal-title":"Genetika"},{"key":"1712_CR34","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2174\/1389200052997393","volume":"6","author":"MC Stuhlinger","year":"2005","unstructured":"Stuhlinger MC, Stanger O (2005) Asymmetric dimethyl-l-arginine (ADMA): a possible link between homocyst(e)ine and endothelial dysfunction. Curr Drug Metab 6:3\u201314","journal-title":"Curr Drug Metab"},{"key":"1712_CR35","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/0098-2997(93)90002-U","volume":"14","author":"PJ Thornalley","year":"1993","unstructured":"Thornalley PJ (1993) The glyoxalase system in health and disease. Mol Aspects Med 14:287\u2013371","journal-title":"Mol Aspects Med"},{"key":"1712_CR36","doi-asserted-by":"crossref","first-page":"6923","DOI":"10.4049\/jimmunol.178.11.6923","volume":"178","author":"CF Towne","year":"2007","unstructured":"Towne CF, York IA, Watkin LB, Lazo JS, Rock KL (2007) Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses. J Immunol 178:6923\u20136930","journal-title":"J Immunol"},{"key":"1712_CR37","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.bbrc.2010.05.104","volume":"397","author":"F Vasuri","year":"2010","unstructured":"Vasuri F, Capizzi E, Bellavista E, Mishto M, Santoro A, Fiorentino M, Capri M, Cescon M, Grazi GL, Grigioni WF, D\u2019Errico-Grigioni A, Franceschi C (2010) Studies on immunoproteasome in human liver. Part I: absence in fetuses, presence in normal subjects, and increased levels in chronic active hepatitis and cirrhosis. Biochem Biophys Res Commun 397:301\u2013306","journal-title":"Biochem Biophys Res Commun"},{"key":"1712_CR38","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1016\/j.jnutbio.2007.05.005","volume":"19","author":"W Velez-Carrasco","year":"2008","unstructured":"Velez-Carrasco W, Merkel M, Twiss CO, Smith JD (2008) Dietary methionine effects on plasma homocysteine and HDL metabolism in mice. J Nutr Biochem 19:362\u2013370","journal-title":"J Nutr Biochem"},{"key":"1712_CR39","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1172\/JCI11596","volume":"107","author":"GH Werstuck","year":"2001","unstructured":"Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, Zhou J, Maeda N, Krisans SK, Malinow MR, Austin RC (2001) Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. J Clin Invest 107:1263\u20131273","journal-title":"J Clin Invest"},{"key":"1712_CR40","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1476-511X-10-137","volume":"10","author":"Y Xiao","year":"2011","unstructured":"Xiao Y, Zhang Y, Lv X, Su D, Li D, Xia M, Qiu J, Ling W, Ma J (2011) Relationship between lipid profiles and plasma total homocysteine, cysteine and the risk of coronary artery disease in coronary angiographic subjects. Lipids Health Dis 10:137","journal-title":"Lipids Health Dis"},{"key":"1712_CR41","doi-asserted-by":"crossref","unstructured":"Yalcin EB, More VR, Neira K, Lu ZJ, Cherrington NJ, Slitt AL, King RS (2013) Down-regulation of sulfotransferase expression and activity in diseased human livers. Drug Metab Dispos","DOI":"10.1124\/dmd.113.050930"},{"key":"1712_CR42","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1515\/CCLM.2011.107","volume":"49","author":"M Zaabczyk","year":"2011","unstructured":"Zaabczyk M, Glowacki R, Machnik A, Herod P, Kazek G, Jakubowski H, Undas A (2011) Elevated concentrations of Nvarepsilon\u2013homocysteinyl\u2013lysine isopeptide in acute myocardial infarction: links with ADMA formation. Clin Chem Lab Med CCLM\/FESCC 49:729\u2013735","journal-title":"Clin Chem Lab Med CCLM\/FESCC"},{"key":"1712_CR43","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1161\/hq0901.096582","volume":"21","author":"J Zhou","year":"2001","unstructured":"Zhou J, Moller J, Danielsen CC, Bentzon J, Ravn HB, Austin RC, Falk E (2001) Dietary supplementation with methionine and homocysteine promotes early atherosclerosis but not plaque rupture in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 21:1470\u20131476","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"1712_CR44","doi-asserted-by":"crossref","first-page":"22485","DOI":"10.1074\/jbc.M603656200","volume":"281","author":"J Zimny","year":"2006","unstructured":"Zimny J, Sikora M, Guranowski A, Jakubowski H (2006) Protective mechanisms against homocysteine toxicity: the role of bleomycin hydrolase. J Biol Chem 281:22485\u201322492","journal-title":"J Biol Chem"}],"container-title":["Amino Acids"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-014-1712-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00726-014-1712-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-014-1712-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,11]],"date-time":"2023-07-11T07:22:39Z","timestamp":1689060159000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00726-014-1712-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,16]]},"references-count":44,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["1712"],"URL":"https:\/\/doi.org\/10.1007\/s00726-014-1712-4","relation":{},"ISSN":["0939-4451","1438-2199"],"issn-type":[{"value":"0939-4451","type":"print"},{"value":"1438-2199","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,16]]}}}