{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T05:15:52Z","timestamp":1761110152251,"version":"3.37.3"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,11,23]],"date-time":"2015-11-23T00:00:00Z","timestamp":1448236800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"the state education ministry","award":["[2014] 1685"],"award-info":[{"award-number":["[2014] 1685"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81101068","81471707"],"award-info":[{"award-number":["81101068","81471707"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Amino Acids"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1007\/s00726-015-2129-4","type":"journal-article","created":{"date-parts":[[2015,11,22]],"date-time":"2015-11-22T21:47:00Z","timestamp":1448228820000},"page":"811-820","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["PET monitoring angiogenesis of infarcted myocardium after treatment with vascular endothelial growth factor and bone marrow mesenchymal stem cells"],"prefix":"10.1007","volume":"48","author":[{"given":"Mengting","family":"Cai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoqin","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhide","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yesen","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongxiang","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tingting","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianzhong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuo","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,11,23]]},"reference":[{"issue":"7","key":"2129_CR1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/0092-8674(94)90007-8","volume":"79","author":"PC Brooks","year":"1994","unstructured":"Brooks PC, Montgomery AM, Rosenfeld M, Reisfeld RA, Hu T, Klier G, Cheresh DA (1994) Integrin \u03b1v\u03b23 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79(7):1157\u20131164","journal-title":"Cell"},{"issue":"4","key":"2129_CR2","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1007\/s00259-011-2052-1","volume":"39","author":"H Gao","year":"2012","unstructured":"Gao H, Lang L, Guo N, Cao F, Quan Q, Hu S, Kiesewetter DO, Niu G, Chen X (2012) PET imaging of angiogenesis after myocardial infarction\/reperfusion using a one-step labeled integrin-targeted tracer 18F-AlF-NOTA-PRGD2. Eur J Nucl Med Mol Imagin 39(4):683\u2013692","journal-title":"Eur J Nucl Med Mol Imagin"},{"issue":"2","key":"2129_CR3","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1007\/s11307-013-0668-1","volume":"16","author":"J Guo","year":"2014","unstructured":"Guo J, Lang L, Hu S, Guo N, Zhu L, Sun Z, Ma Y, Kiesewetter DO, Niu G, Xie Q, Chen X (2014) Comparison of three dimeric 18F-AlF-NOTA-RGD tracers. Mol Imagin Biol 16(2):274\u2013283","journal-title":"Mol Imagin Biol"},{"issue":"1","key":"2129_CR4","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ijcard.2008.12.108","volume":"142","author":"K Hagikura","year":"2010","unstructured":"Hagikura K, Fukuda N, Yokoyama S, Yuxin L, Kusumi Y, Matsumoto T, Ikeda Y, Kunimoto S, Takayama T, Jumabay M, Mitsumata M, Saito S, Hirayama A, Mugishima H (2010) Low invasive angiogenic therapy for myocardial infarction by retrograde transplantation of mononuclear cells expressing the VEGF gene. Int J Cardiol 142(1):56\u201364","journal-title":"Int J Cardiol"},{"issue":"6","key":"2129_CR5","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1007\/s00395-008-0741-0","volume":"103","author":"ME Halkos","year":"2008","unstructured":"Halkos ME, Zhao ZQ, Kerendi F, Wang NP, Jiang R, Schmarkey LS, Martin BJ, Quyyumi AA, Few WL, Kin H, Guyton RA, Vinten-Johansen J (2008) Intravenous infusion of mesenchymal stem cells enhances regional perfusion and improves ventricular function in a porcine model of myocardial infarction. Basic Res Cardiol 103(6):525\u2013536","journal-title":"Basic Res Cardiol"},{"issue":"5","key":"2129_CR6","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/gt.2009.4","volume":"16","author":"M Hedman","year":"2009","unstructured":"Hedman M, Muona K, Hedman A, Kivel\u00e4 A, Syv\u00e4nne M, Er\u00e4nen J, Rantala A, Stjernvall J, Nieminen MS, Hartikainen J, Yl\u00e4-Herttuala S (2009) Eight-year safety follow-up of coronary artery disease patients after local intracoronary VEGF gene transfer. Gene Ther 16(5):629\u2013634","journal-title":"Gene Ther"},{"issue":"2","key":"2129_CR7","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1093\/cvr\/cvn033","volume":"78","author":"T Higuchi","year":"2008","unstructured":"Higuchi T, Bengel FM, Seidl S, Watzlowik P, Kessler H, Hegenloh R, Reder S, Nekolla SG, Wester HJ, Schwaiger M (2008) Assessment of \u03b1v\u03b23 integrin expression after myocardial infarction by positron emission tomography. Cardiovasc Res 78(2):395\u2013403","journal-title":"Cardiovasc Res"},{"issue":"4","key":"2129_CR8","first-page":"227","volume":"10","author":"S Hu","year":"2011","unstructured":"Hu S, Cao W, Lan X, He Y, Lang J, Li C, Hu J, An R, Gao Z, Zhang Y (2011) Comparison of rNIS and hNIS as reporter genes for noninvasive imaging of bone mesenchymal stem cells transplanted into infarcted rat myocardium. Mol Imagin 10(4):227\u2013237","journal-title":"Mol Imagin"},{"issue":"4","key":"2129_CR9","doi-asserted-by":"crossref","first-page":"346","DOI":"10.7150\/thno.3694","volume":"2","author":"NF Huang","year":"2012","unstructured":"Huang NF, Okogbaa J, Babakhanyan A, Cooke JP (2012) Bioluminescence imaging of stem cell-based therapeutics for vascular regeneration. Theranostics 2(4):346\u2013354","journal-title":"Theranostics"},{"issue":"10A","key":"2129_CR10","doi-asserted-by":"crossref","first-page":"63S","DOI":"10.1016\/S0002-9149(98)90439-8","volume":"82","author":"JM Isner","year":"1998","unstructured":"Isner JM (1998) Vascular endothelial growth factor: gene therapy and therapeutic angiogenesis. Am J Cardiol 82(10A):63S\u201364S","journal-title":"Am J Cardiol"},{"issue":"3","key":"2129_CR11","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1021\/bc100437q","volume":"22","author":"O Jacobson","year":"2011","unstructured":"Jacobson O, Zhu L, Ma Y, Weiss ID, Sun X, Niu G, Kiesewetter DO, Chen X (2011) Rapid and simple one-step F-18 labeling of peptides. Bioconjug Chem 22(3):422\u2013428","journal-title":"Bioconjug Chem"},{"issue":"1","key":"2129_CR12","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/2191-219X-3-38","volume":"3","author":"I Laitinen","year":"2013","unstructured":"Laitinen I, Notni J, Pohle K, Rudelius M, Farrell E, Nekolla SG, Henriksen G, Neubauer S, Kessler H, Wester HJ, Schwaiger M (2013) Comparison of cyclic RGD peptides for \u03b1v\u03b23 integrin detection in a rat model of myocardial infarction. EJNMMI Res 3(1):38","journal-title":"EJNMMI Res"},{"issue":"7","key":"2129_CR13","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1097\/RLU.0000000000000426","volume":"39","author":"Y Luo","year":"2014","unstructured":"Luo Y, Sun Y, Zhu Z, Li F (2014) Is the change of integrin \u03b1v\u03b23 expression in the infarcted myocardium related to the clinical outcome? Clin Nucl Med 39(7):655\u2013657","journal-title":"Clin Nucl Med"},{"issue":"18","key":"2129_CR14","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1093\/eurheartj\/ehn129","volume":"29","author":"MR Makowski","year":"2008","unstructured":"Makowski MR, Ebersberger U, Nekolla S, Schwaiger M (2008) In vivo molecular imaging of angiogenesis, targeting \u03b1v\u03b23 integrin expression, in a patient after acute myocardial infarction. Eur Heart J 29(18):2201","journal-title":"Eur Heart J"},{"issue":"6","key":"2129_CR15","doi-asserted-by":"crossref","first-page":"991","DOI":"10.2967\/jnumed.108.060418","volume":"50","author":"WJ McBride","year":"2009","unstructured":"McBride WJ, Sharkey RM, Karacay H, D\u2019Souza CA, Rossi EA, Laverman P, Chang CH, Boerman OC, Goldenberg DM (2009) A novel method of 18F radiolabeling for PET. J Nucl Med 50(6):991\u2013998","journal-title":"J Nucl Med"},{"issue":"7","key":"2129_CR16","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1021\/bc100137x","volume":"21","author":"WJ McBride","year":"2010","unstructured":"McBride WJ, D\u2019Souza CA, Sharkey RM, Karacay H, Rossi EA, Chang CH, Goldenberg DM (2010) Improved 18F labeling of peptides with a fluoride-aluminum-chelate complex. Bioconjug Chem 21(7):1331\u20131340","journal-title":"Bioconjug Chem"},{"issue":"12","key":"2129_CR17","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1172\/JCI200420352","volume":"113","author":"DF Meoli","year":"2004","unstructured":"Meoli DF, Sadeghi MM, Krassilnikova S, Bourke BN, Giordano FJ, Dione DP, Su H, Edwards DS, Liu S, Harris TD, Madri JA, Zaret BL, Sinusas AJ (2004) Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction. J Clin Invest 113(12):1684\u20131691","journal-title":"J Clin Invest"},{"issue":"5","key":"2129_CR18","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1016\/j.biomaterials.2013.11.019","volume":"35","author":"HH Moon","year":"2014","unstructured":"Moon HH, Joo MK, Mok H, Lee M, Hwang KC, Kim SW, Jeong JH, Choi D, Kim SH (2014) MSC-based VEGF gene therapy in rat myocardial infarction model using facial amphipathic bile acid-conjugated polyethyleneimine. Biomaterials 35(5):1744\u20131754","journal-title":"Biomaterials"},{"key":"2129_CR19","doi-asserted-by":"crossref","first-page":"30","DOI":"10.7150\/thno\/v01p0030","volume":"1","author":"G Niu","year":"2011","unstructured":"Niu G, Chen X (2011) Why integrin as a primary target for imaging and therapy. Theranostics 1:30\u201347","journal-title":"Theranostics"},{"issue":"1","key":"2129_CR20","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1177\/107424840601100102","volume":"11","author":"MA Nordlie","year":"2006","unstructured":"Nordlie MA, Wold LE, Simkhovich BZ, Sesti C, Kloner RA (2006) Molecular aspects of ischemic heart disease: ischemia\/reperfusion-induced genetic changes and potential applications of gene and RNA interference therapy. J Cardiovasc Pharmacol Ther 11(1):17\u201330","journal-title":"J Cardiovasc Pharmacol Ther"},{"issue":"2","key":"2129_CR21","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.bbrc.2008.09.003","volume":"376","author":"J Pons","year":"2008","unstructured":"Pons J, Huang Y, Arakawa-Hoyt J, Washko D, Takagawa J, Ye J, Grossman W, Su H (2008) VEGF improves survival of mesenchymal stem cells in infarcted hearts. Biochem Biophys Res Commun 376(2):419\u2013422","journal-title":"Biochem Biophys Res Commun"},{"issue":"7181","key":"2129_CR22","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1038\/nature06800","volume":"451","author":"VF Segers","year":"2008","unstructured":"Segers VF, Lee RT (2008) Stem-cell therapy for cardiac disease. Nature 451(7181):937\u2013942","journal-title":"Nature"},{"issue":"2","key":"2129_CR23","doi-asserted-by":"crossref","first-page":"318","DOI":"10.2967\/jnumed.111.091652","volume":"53","author":"HM Sherif","year":"2012","unstructured":"Sherif HM, Saraste A, Nekolla SG, Weidl E, Reder S, Tapfer A, Rudelius M, Higuchi T, Botnar RM, Wester HJ, Schwaiger M (2012) Molecular imaging of early \u03b1v\u03b23 integrin expression predicts long-term left-ventricle remodeling after myocardial infarction in rats. J Nucl Med 53(2):318\u2013323","journal-title":"J Nucl Med"},{"issue":"8","key":"2129_CR24","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/nrcardio.2009.103","volume":"6","author":"AM Laan van der","year":"2009","unstructured":"van der Laan AM, Piek JJ, van Royen N (2009) Targeting angiogenesis to restore the microcirculation after reperfused MI. Nat Rev Cardiol 6(8):515\u2013523","journal-title":"Nat Rev Cardiol"},{"issue":"1","key":"2129_CR25","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.biomaterials.2013.09.080","volume":"35","author":"TS Yeh","year":"2014","unstructured":"Yeh TS, Fang YH, Lu CH, Chiu SC, Yeh CL, Yen TC, Parfyonova Y, Hu YC (2014) Baculovirus-transduced, VEGF-expressing adipose-derived stem cell sheet for the treatment of myocardium infarction. Biomaterials 35(1):174\u2013184","journal-title":"Biomaterials"},{"issue":"10","key":"2129_CR26","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.jacc.2006.09.053","volume":"49","author":"S Yl\u00e4-Herttuala","year":"2007","unstructured":"Yl\u00e4-Herttuala S, Rissanen TT, Vajanto I, Hartikainen J (2007) Vascular endothelial growth factors: biology and current status of clinical applications in cardiovascular medicine. J Am Coll Cardiol 49(10):1015\u20131026","journal-title":"J Am Coll Cardiol"}],"container-title":["Amino Acids"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-015-2129-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00726-015-2129-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-015-2129-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T01:42:11Z","timestamp":1559094131000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00726-015-2129-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,23]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["2129"],"URL":"https:\/\/doi.org\/10.1007\/s00726-015-2129-4","relation":{},"ISSN":["0939-4451","1438-2199"],"issn-type":[{"type":"print","value":"0939-4451"},{"type":"electronic","value":"1438-2199"}],"subject":[],"published":{"date-parts":[[2015,11,23]]}}}