{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:27:01Z","timestamp":1786980421718,"version":"build-2736575974"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Amino Acids"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1007\/s00726-021-03074-9","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T12:03:06Z","timestamp":1631016186000},"page":"1533-1543","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Angiotensin-(3\u20137) alleviates isoprenaline-induced cardiac remodeling via attenuating cAMP-PKA and PI3K\/Akt signaling pathways"],"prefix":"10.1007","volume":"53","author":[{"given":"Yonglin","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenglu","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5526-7683","authenticated-orcid":false,"given":"Aijun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,7]]},"reference":[{"key":"3074_CR1","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1016\/j.vph.2015.05.008","volume":"74","author":"P Abeyrathna","year":"2015","unstructured":"Abeyrathna P, Su Y (2015) The critical role of Akt in cardiovascular function. Vascul Pharmacol 74:38\u201348. https:\/\/doi.org\/10.1016\/j.vph.2015.05.008","journal-title":"Vascul Pharmacol"},{"key":"3074_CR2","doi-asserted-by":"publisher","first-page":"170439","DOI":"10.1016\/j.peptides.2020.170439","volume":"136","author":"GMF Andrade-Franze","year":"2021","unstructured":"Andrade-Franze GMF, Pereira ED Jr, Yosten GLC, Samson WK, Menani JV, De Luca LA Jr, Andrade CAF (2021) Blockade of ERK1\/2 activation with U0126 or PEP7 reduces sodium appetite and angiotensin II-induced pressor responses in spontaneously hypertensive rats. Peptides 136:170439. https:\/\/doi.org\/10.1016\/j.peptides.2020.170439","journal-title":"Peptides"},{"issue":"9","key":"3074_CR3","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.1093\/jn\/nxaa144","volume":"150","author":"CY Asselin","year":"2020","unstructured":"Asselin CY, Lam A, Cheung DYC, Eekhoudt CR, Zhu A, Mittal I, Mayba A, Solati Z, Edel A, Austria JA, Aukema HM, Ravandi A, Thliveris J, Singal PK, Pierce GN, Niraula S, Jassal DS (2020) The cardioprotective role of flaxseed in the prevention of doxorubicin- and trastuzumab-mediated cardiotoxicity in C57BL\/6 mice. J Nutr 150(9):2353\u20132363. https:\/\/doi.org\/10.1093\/jn\/nxaa144","journal-title":"J Nutr"},{"key":"3074_CR4","doi-asserted-by":"publisher","DOI":"10.3390\/cells9010069","author":"M Delaunay","year":"2019","unstructured":"Delaunay M, Osman H, Kaiser S, Diviani D (2019) The role of cyclic AMP signaling in cardiac fibrosis. Cells. https:\/\/doi.org\/10.3390\/cells9010069","journal-title":"Cells"},{"issue":"17","key":"3074_CR5","doi-asserted-by":"publisher","first-page":"2204","DOI":"10.1016\/j.jacc.2020.03.019","volume":"75","author":"J Diez","year":"2020","unstructured":"Diez J, Gonzalez A, Kovacic JC (2020) Myocardial interstitial fibrosis in nonischemic heart disease, part 3\/4: JACC focus seminar. J Am Coll Cardiol 75(17):2204\u20132218. https:\/\/doi.org\/10.1016\/j.jacc.2020.03.019","journal-title":"J Am Coll Cardiol"},{"issue":"1\u20133","key":"3074_CR6","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1016\/j.regpep.2006.12.031","volume":"141","author":"PM Ferreira","year":"2007","unstructured":"Ferreira PM, Souza Dos Santos RA, Campagnole-Santos MJ (2007) Angiotensin-(3\u20137) pressor effect at the rostral ventrolateral medulla. Regul Pept 141(1\u20133):168\u2013174. https:\/\/doi.org\/10.1016\/j.regpep.2006.12.031","journal-title":"Regul Pept"},{"key":"3074_CR7","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20092164","author":"S Gallo","year":"2019","unstructured":"Gallo S, Vitacolonna A, Bonzano A, Comoglio P, Crepaldi T (2019) ERK: a key player in the pathophysiology of cardiac hypertrophy. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms20092164","journal-title":"Int J Mol Sci"},{"key":"3074_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.107133","volume":"90","author":"RF Gao","year":"2021","unstructured":"Gao RF, Li X, Xiang HY, Yang H, Lv CY, Sun XL, Chen HZ, Gao Y, Yang JS, Luo W, Yang YQ, Tang YH (2021) The covalent NLRP3-inflammasome inhibitor Oridonin relieves myocardial infarction induced myocardial fibrosis and cardiac remodeling in mice. Int Immunopharmacol 90:107133. https:\/\/doi.org\/10.1016\/j.intimp.2020.107133","journal-title":"Int Immunopharmacol"},{"key":"3074_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2019.170101","volume":"118","author":"J Gong","year":"2019","unstructured":"Gong J, Shen Y, Li P, Zhao K, Chen X, Li Y, Sheng Y, Zhou B, Kong X (2019) Superoxide anions mediate the effects of angiotensin (1\u20137) analog, alamandine, on blood pressure and sympathetic activity in the paraventricular nucleus. Peptides 118:170101. https:\/\/doi.org\/10.1016\/j.peptides.2019.170101","journal-title":"Peptides"},{"issue":"2","key":"3074_CR10","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1080\/00015385.2018.1559485","volume":"75","author":"RN Horodinschi","year":"2020","unstructured":"Horodinschi RN, Bratu OG, Dediu GN, Pantea Stoian A, Motofei I, Diaconu CC (2020) Heart failure and chronic obstructive pulmonary disease: a review. Acta Cardiol 75(2):97\u2013104. https:\/\/doi.org\/10.1080\/00015385.2018.1559485","journal-title":"Acta Cardiol"},{"issue":"1","key":"3074_CR11","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1111\/fcp.12318","volume":"32","author":"N Kittana","year":"2018","unstructured":"Kittana N (2018) Angiotensin-converting enzyme 2-Angiotensin 1\u20137\/1-9 system: novel promising targets for heart failure treatment. Fundam Clin Pharmacol 32(1):14\u201325. https:\/\/doi.org\/10.1111\/fcp.12318","journal-title":"Fundam Clin Pharmacol"},{"issue":"1","key":"3074_CR12","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1111\/jcmm.16052","volume":"25","author":"C Li","year":"2021","unstructured":"Li C, Miao X, Wang S, Liu Y, Sun J, Liu Q, Cai L, Wang Y (2021) Elabela may regulate SIRT3-mediated inhibition of oxidative stress through Foxo3a deacetylation preventing diabetic-induced myocardial injury. J Cell Mol Med 25(1):323\u2013332. https:\/\/doi.org\/10.1111\/jcmm.16052","journal-title":"J Cell Mol Med"},{"issue":"1","key":"3074_CR13","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1111\/j.1755-5922.2010.00205.x","volume":"30","author":"PJ Lijnen","year":"2012","unstructured":"Lijnen PJ, van Pelt JF, Fagard RH (2012) Stimulation of reactive oxygen species and collagen synthesis by angiotensin II in cardiac fibroblasts. Cardiovasc Ther 30(1):e1-8. https:\/\/doi.org\/10.1111\/j.1755-5922.2010.00205.x","journal-title":"Cardiovasc Ther"},{"issue":"8","key":"3074_CR14","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1007\/s00726-018-2583-x","volume":"50","author":"C Liu","year":"2018","unstructured":"Liu C, Yang CX, Chen XR, Liu BX, Li Y, Wang XZ, Sun W, Li P, Kong XQ (2018) Alamandine attenuates hypertension and cardiac hypertrophy in hypertensive rats. Amino Acids 50(8):1071\u20131081. https:\/\/doi.org\/10.1007\/s00726-018-2583-x","journal-title":"Amino Acids"},{"key":"3074_CR15","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.16304","author":"L Lyu","year":"2021","unstructured":"Lyu L, Chen J, Wang W, Yan T, Lin J, Gao H, Li H, Lv R, Xu F, Fang L, Chen Y (2021) Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress. J Cell Mol Med. https:\/\/doi.org\/10.1111\/jcmm.16304","journal-title":"J Cell Mol Med"},{"key":"3074_CR16","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd6020014","author":"A Nehme","year":"2019","unstructured":"Nehme A, Zouein FA, Zayeri ZD, Zibara K (2019) An update on the tissue renin angiotensin system and its role in physiology and pathology. J Cardiovasc Dev Dis. https:\/\/doi.org\/10.3390\/jcdd6020014","journal-title":"J Cardiovasc Dev Dis"},{"issue":"3","key":"3074_CR17","doi-asserted-by":"publisher","first-page":"895","DOI":"10.1007\/s00726-010-0728-7","volume":"40","author":"GA Ngoh","year":"2011","unstructured":"Ngoh GA, Watson LJ, Facundo HT, Jones SP (2011) Augmented O-GlcNAc signaling attenuates oxidative stress and calcium overload in cardiomyocytes. Amino Acids 40(3):895\u2013911. https:\/\/doi.org\/10.1007\/s00726-010-0728-7","journal-title":"Amino Acids"},{"issue":"3","key":"3074_CR18","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1093\/cvr\/cvy230","volume":"115","author":"SL Puhl","year":"2019","unstructured":"Puhl SL, Weeks KL, Guran A, Ranieri A, Boknik P, Kirchhefer U, Muller FU, Avkiran M (2019) Role of type 2A phosphatase regulatory subunit B56alpha in regulating cardiac responses to beta-adrenergic stimulation in vivo. Cardiovasc Res 115(3):519\u2013529. https:\/\/doi.org\/10.1093\/cvr\/cvy230","journal-title":"Cardiovasc Res"},{"issue":"1\u20132","key":"3074_CR19","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s11010-016-2849-0","volume":"424","author":"V Rai","year":"2017","unstructured":"Rai V, Sharma P, Agrawal S, Agrawal DK (2017) Relevance of mouse models of cardiac fibrosis and hypertrophy in cardiac research. Mol Cell Biochem 424(1\u20132):123\u2013145. https:\/\/doi.org\/10.1007\/s11010-016-2849-0","journal-title":"Mol Cell Biochem"},{"key":"3074_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2020.170384","volume":"133","author":"D Raupp","year":"2020","unstructured":"Raupp D, Fernandes RS, Antunes KH, Perin FA, Rigatto K (2020) Impact of angiotensin II type 1 and G-protein-coupled Mas receptor expression on the pulmonary performance of patients with idiopathic pulmonary fibrosis. Peptides 133:170384. https:\/\/doi.org\/10.1016\/j.peptides.2020.170384","journal-title":"Peptides"},{"issue":"6","key":"3074_CR21","doi-asserted-by":"publisher","first-page":"2523","DOI":"10.1159\/000480214","volume":"42","author":"X Ren","year":"2017","unstructured":"Ren X, Zhang F, Zhao M, Zhao Z, Sun S, Fraidenburg DR, Tang H, Han Y (2017) Angiotensin-(1\u20137) in paraventricular nucleus contributes to the enhanced cardiac sympathetic afferent reflex and sympathetic activity in chronic heart failure rats. Cell Physiol Biochem 42(6):2523\u20132539. https:\/\/doi.org\/10.1159\/000480214","journal-title":"Cell Physiol Biochem"},{"issue":"1\u20132","key":"3074_CR22","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s11010-017-3253-0","volume":"445","author":"N Saleem","year":"2018","unstructured":"Saleem N, Prasad A, Goswami SK (2018) Apocynin prevents isoproterenol-induced cardiac hypertrophy in rat. Mol Cell Biochem 445(1\u20132):79\u201388. https:\/\/doi.org\/10.1007\/s11010-017-3253-0","journal-title":"Mol Cell Biochem"},{"key":"3074_CR23","doi-asserted-by":"publisher","first-page":"75","DOI":"10.12659\/MSMBR.900437","volume":"22","author":"M Samak","year":"2016","unstructured":"Samak M, Fatullayev J, Sabashnikov A, Zeriouh M, Schmack B, Farag M, Popov AF, Dohmen PM, Choi YH, Wahlers T, Weymann A (2016) Cardiac hypertrophy: an introduction to molecular and cellular basis. Med Sci Monit Basic Res 22:75\u201379. https:\/\/doi.org\/10.12659\/MSMBR.900437","journal-title":"Med Sci Monit Basic Res"},{"issue":"5","key":"3074_CR24","doi-asserted-by":"publisher","first-page":"H1365","DOI":"10.1152\/ajpheart.00608.2009","volume":"298","author":"A Shah","year":"2010","unstructured":"Shah A, Gul R, Yuan K, Gao S, Oh YB, Kim UH, Kim SH (2010) Angiotensin-(1\u20137) stimulates high atrial pacing-induced ANP secretion via Mas\/PI3-kinase\/Akt axis and Na+\/H+ exchanger. Am J Physiol Heart Circ Physiol 298(5):H1365-1374. https:\/\/doi.org\/10.1152\/ajpheart.00608.2009","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"1","key":"3074_CR25","doi-asserted-by":"publisher","first-page":"H352","DOI":"10.1152\/ajpheart.00328.2020","volume":"320","author":"MM Silva","year":"2021","unstructured":"Silva MM, de Souza-Neto FP, Jesus ICG, Goncalves GK, Santuchi MC, Sanches BL, de Alcantara-Leonidio TC, Melo MB, Vieira MAR, Guatimosim S, Santos RAS, da Silva RF (2021) Alamandine improves cardiac remodeling induced by transverse aortic constriction in mice. Am J Physiol Heart Circ Physiol 320(1):H352\u2013H363. https:\/\/doi.org\/10.1152\/ajpheart.00328.2020","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"4","key":"3074_CR26","doi-asserted-by":"publisher","first-page":"209","DOI":"10.14744\/AnatolJCardiol.2019.40072","volume":"23","author":"A Soltani Hekmat","year":"2020","unstructured":"Soltani Hekmat A, Javanmardi K, Tavassoli A, Gholampour Y (2020) Angiotensin (1\u20137) and apelin co-therapy: new strategy for heart failure treatment of rats. Anatol J Cardiol 23(4):209\u2013217. https:\/\/doi.org\/10.14744\/AnatolJCardiol.2019.40072","journal-title":"Anatol J Cardiol"},{"issue":"7","key":"3074_CR27","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.14812","volume":"9","author":"FF Stoyell-Conti","year":"2021","unstructured":"Stoyell-Conti FF, Chabbra A, Puthentharayil J, Rigatto K, Speth RC (2021) Chronic administration of pharmacological doses of angiotensin 1\u20137 and iodoangiotensin 1\u20137 has minimal effects on blood pressure, heart rate, and cognitive function of spontaneously hypertensive rats. Physiol Rep 9(7):e14812. https:\/\/doi.org\/10.14814\/phy2.14812","journal-title":"Physiol Rep"},{"key":"3074_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2020.173690","volume":"891","author":"TL Sun","year":"2021","unstructured":"Sun TL, Li WQ, Tong XL, Liu XY, Zhou WH (2021a) Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN\/AKT\/mTOR pathway. Eur J Pharmacol 891:173690. https:\/\/doi.org\/10.1016\/j.ejphar.2020.173690","journal-title":"Eur J Pharmacol"},{"issue":"1","key":"3074_CR29","doi-asserted-by":"publisher","first-page":"H364","DOI":"10.1152\/ajpheart.00523.2020","volume":"320","author":"Z Sun","year":"2021","unstructured":"Sun Z, Zhang L, Li L, Shao C, Liu J, Zhou M, Wang Z (2021b) Galectin-3 mediates cardiac remodeling caused by impaired glucose and lipid metabolism through inhibiting two pathways of activating Akt. Am J Physiol Heart Circ Physiol 320(1):H364\u2013H380. https:\/\/doi.org\/10.1152\/ajpheart.00523.2020","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"4","key":"3074_CR30","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1291\/hypres.25.491","volume":"25","author":"H Takano","year":"2002","unstructured":"Takano H, Zou Y, Akazawa H, Toko H, Mizukami M, Hasegawa H, Asakawa M, Nagai T, Komuro I (2002) Inhibitory molecules in signal transduction pathways of cardiac hypertrophy. Hypertens Res 25(4):491\u2013498. https:\/\/doi.org\/10.1291\/hypres.25.491","journal-title":"Hypertens Res"},{"issue":"6","key":"3074_CR31","doi-asserted-by":"publisher","first-page":"4553","DOI":"10.3892\/mmr.2019.10167","volume":"19","author":"L Wang","year":"2019","unstructured":"Wang L, Liu C, Chen X, Li P (2019) Alamandine attenuates longterm hypertensioninduced cardiac fibrosis independent of blood pressure. Mol Med Rep 19(6):4553\u20134560. https:\/\/doi.org\/10.3892\/mmr.2019.10167","journal-title":"Mol Med Rep"},{"issue":"10","key":"3074_CR32","doi-asserted-by":"publisher","first-page":"165848","DOI":"10.1016\/j.bbadis.2020.165848","volume":"1866","author":"CN Xu","year":"2020","unstructured":"Xu CN, Kong LH, Ding P, Liu Y, Fan ZG, Gao EH, Yang J, Yang LF (2020) Melatonin ameliorates pressure overload-induced cardiac hypertrophy by attenuating Atg5-dependent autophagy and activating the Akt\/mTOR pathway. Biochim Biophys Acta Mol Basis Dis 1866(10):165848. https:\/\/doi.org\/10.1016\/j.bbadis.2020.165848","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"key":"3074_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2021.170612","volume":"144","author":"H Xu","year":"2021","unstructured":"Xu H, An X, Tian J, Fu M, Wang Q, Li C, He X, Niu L (2021) Angiotensin-(1\u20137) protects against sepsis-associated left ventricular dysfunction induced by lipopolysaccharide. Peptides 144:170612. https:\/\/doi.org\/10.1016\/j.peptides.2021.170612","journal-title":"Peptides"},{"issue":"11","key":"3074_CR34","doi-asserted-by":"publisher","first-page":"1425","DOI":"10.3760\/cma.j.issn.2095-4352.2019.11.022","volume":"31","author":"L Yang","year":"2019","unstructured":"Yang L, Huang Y, He Q (2019) Regulation of angiotensin-converting enzyme 2-angiotensin (1\u20137)-Mas axis provides a new target for the treatment of cardiac remodeling and heart failure. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 31(11):1425\u20131428. https:\/\/doi.org\/10.3760\/cma.j.issn.2095-4352.2019.11.022","journal-title":"Zhonghua Wei Zhong Bing Ji Jiu Yi Xue"},{"key":"3074_CR35","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2020.173384","volume":"883","author":"C Yang","year":"2020","unstructured":"Yang C, Wu X, Shen Y, Liu C, Kong X, Li P (2020) Alamandine attenuates angiotensin II-induced vascular fibrosis via inhibiting p38 MAPK pathway. Eur J Pharmacol 883:173384. https:\/\/doi.org\/10.1016\/j.ejphar.2020.173384","journal-title":"Eur J Pharmacol"},{"issue":"38","key":"3074_CR36","doi-asserted-by":"publisher","first-page":"26107","DOI":"10.1074\/jbc.M114.582809","volume":"289","author":"T Yoshida","year":"2014","unstructured":"Yoshida T, Yamashita M, Horimai C, Hayashi M (2014) Kruppel-like factor 4 protein regulates isoproterenol-induced cardiac hypertrophy by modulating myocardin expression and activity. J Biol Chem 289(38):26107\u201326118. https:\/\/doi.org\/10.1074\/jbc.M114.582809","journal-title":"J Biol Chem"},{"issue":"1","key":"3074_CR37","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCHEARTFAILURE.120.007684","volume":"14","author":"SR Yurista","year":"2021","unstructured":"Yurista SR, Matsuura TR, Sillje HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD (2021) Ketone ester treatment improves cardiac function and reduces pathologic remodeling in preclinical models of heart failure. Circ Heart Fail 14(1):e007684. https:\/\/doi.org\/10.1161\/CIRCHEARTFAILURE.120.007684","journal-title":"Circ Heart Fail"},{"key":"3074_CR38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2020.172941","volume":"872","author":"J Zhang","year":"2020","unstructured":"Zhang J, Wei X, Zhang W, Wang F, Li Q (2020) MiR-326 targets MDK to regulate the progression of cardiac hypertrophy through blocking JAK\/STAT and MAPK signaling pathways. Eur J Pharmacol 872:172941. https:\/\/doi.org\/10.1016\/j.ejphar.2020.172941","journal-title":"Eur J Pharmacol"},{"key":"3074_CR39","doi-asserted-by":"publisher","first-page":"8881843","DOI":"10.1155\/2021\/8881843","volume":"2021","author":"X Zhang","year":"2021","unstructured":"Zhang X, Ke PX, Yuan X, Zhang GP, Chen WL, Zhang GS (2021) Forskolin protected against streptozotocin-induced diabetic cardiomyopathy via inhibition of oxidative stress and cardiac fibrosis in mice. Biomed Res Int 2021:8881843. https:\/\/doi.org\/10.1155\/2021\/8881843","journal-title":"Biomed Res Int"},{"key":"3074_CR40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2020.173386","volume":"883","author":"J Zheng","year":"2020","unstructured":"Zheng J, Tian J, Wang S, Hu P, Wu Q, Shan X, Zhao P, Zhang C, Guo W, Xu M, Chen H, Lu R (2020) Stachydrine hydrochloride suppresses phenylephrine-induced pathological cardiac hypertrophy by inhibiting the calcineurin\/nuclear factor of activated T-cell signalling pathway. Eur J Pharmacol 883:173386. https:\/\/doi.org\/10.1016\/j.ejphar.2020.173386","journal-title":"Eur J Pharmacol"},{"issue":"4","key":"3074_CR41","doi-asserted-by":"publisher","first-page":"R143","DOI":"10.1530\/JME-16-0086","volume":"57","author":"L Zhou","year":"2016","unstructured":"Zhou L, Ma B, Han X (2016) The role of autophagy in angiotensin II-induced pathological cardiac hypertrophy. J Mol Endocrinol 57(4):R143\u2013R152. https:\/\/doi.org\/10.1530\/JME-16-0086","journal-title":"J Mol Endocrinol"}],"container-title":["Amino Acids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-021-03074-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00726-021-03074-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-021-03074-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,15]],"date-time":"2021-10-15T06:25:52Z","timestamp":1634279152000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00726-021-03074-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,7]]},"references-count":41,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["3074"],"URL":"https:\/\/doi.org\/10.1007\/s00726-021-03074-9","relation":{},"ISSN":["0939-4451","1438-2199"],"issn-type":[{"value":"0939-4451","type":"print"},{"value":"1438-2199","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,7]]},"assertion":[{"value":"10 May 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 September 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare that no competing financial interests exist.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving animals were in accordance with the ethical standards of Binhai County People's Hospital in which the studies were conducted.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}