{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T03:24:56Z","timestamp":1740108296624,"version":"3.37.3"},"reference-count":62,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T00:00:00Z","timestamp":1681689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T00:00:00Z","timestamp":1681689600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Amino Acids"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1007\/s00726-023-03266-5","type":"journal-article","created":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T08:02:32Z","timestamp":1681718552000},"page":"757-767","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["In silico analysis of the possible crosstalk between O-linked \u03b2-GlcNAcylation and phosphorylation sites of Disabled 1 adaptor protein in vertebrates"],"prefix":"10.1007","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3367-9075","authenticated-orcid":false,"given":"Ramiz","family":"Demir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6435-7883","authenticated-orcid":false,"given":"Remziye","family":"Deveci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,4,17]]},"reference":[{"issue":"4","key":"3266_CR1","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1002\/PROT.20530","volume":"60","author":"RJ Anderson","year":"2005","unstructured":"Anderson RJ, Weng Z, Campbell RK, Jiang X (2005) Main-chain conformational tendencies of amino acids. Proteins: Struct, Funct, Bioinf 60(4):679\u2013689. https:\/\/doi.org\/10.1002\/PROT.20530","journal-title":"Proteins: Struct, Funct, Bioinf"},{"issue":"2","key":"3266_CR2","doi-asserted-by":"publisher","first-page":"271","DOI":"10.3892\/IJMM.2017.3036","volume":"40","author":"F Ardito","year":"2017","unstructured":"Ardito F, Giuliani M, Perrone D, Troiano G, Lo Muzio L (2017) The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review). Int J Mol Med 40(2):271. https:\/\/doi.org\/10.3892\/IJMM.2017.3036","journal-title":"Int J Mol Med"},{"issue":"3","key":"3266_CR3","doi-asserted-by":"publisher","first-page":"270","DOI":"10.1038\/ng1257","volume":"35","author":"AH Assadi","year":"2003","unstructured":"Assadi AH, Zhang G, Beffert U, McNeil RS, Renfro AL, Niu S, Quattrocchi CC, Antalffy BA, Sheldon M, Armstrong DD, Wynshaw-Boris A, Herz J, D\u2019Arcangelo G, Clark GD (2003) Interaction of reelin signaling and Lis1 in brain development. Nat Genet 35(3):270\u2013276. https:\/\/doi.org\/10.1038\/ng1257","journal-title":"Nat Genet"},{"issue":"7541","key":"3266_CR4","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1038\/nature13999","volume":"519","author":"A Bah","year":"2014","unstructured":"Bah A, Vernon RM, Siddiqui Z, Krzeminski M, Muhandiram R, Zhao C, Sonenberg N, Kay LE, Forman-Kay JD (2014) Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch. Nature 519(7541):106\u2013109. https:\/\/doi.org\/10.1038\/nature13999","journal-title":"Nature"},{"issue":"7","key":"3266_CR5","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1016\/J.CUB.2004.03.038","volume":"14","author":"BA Ballif","year":"2004","unstructured":"Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA (2004) Activation of a Dab1\/CrkL\/C3G\/Rap1 pathway in Reelin-stimulated neurons. Curr Biol 14(7):606\u2013610. https:\/\/doi.org\/10.1016\/J.CUB.2004.03.038","journal-title":"Curr Biol"},{"key":"3266_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/J.MAM.2016.05.005","volume":"51","author":"PS Banerjee","year":"2016","unstructured":"Banerjee PS, Lagerl\u00f6f O, Hart GW (2016) Roles of O-GlcNAc in chronic diseases of aging. Mol Aspects Med 51:1\u201315. https:\/\/doi.org\/10.1016\/J.MAM.2016.05.005","journal-title":"Mol Aspects Med"},{"issue":"1\u20132","key":"3266_CR7","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/S0169-328X(03)00032-9","volume":"112","author":"D Benhayon","year":"2003","unstructured":"Benhayon D, Magdaleno S, Curran T (2003) Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1. Mol Brain Res 112(1\u20132):33\u201345. https:\/\/doi.org\/10.1016\/S0169-328X(03)00032-9","journal-title":"Mol Brain Res"},{"key":"3266_CR8","doi-asserted-by":"publisher","first-page":"105467","DOI":"10.1016\/J.PHRS.2021.105467","volume":"165","author":"IO Bolanle","year":"2021","unstructured":"Bolanle IO, Riches-Suman K, Williamson R, Palmer TM (2021) Emerging roles of protein O-GlcNAcylation in cardiovascular diseases: insights and novel therapeutic targets. Pharmacol Res 165:105467. https:\/\/doi.org\/10.1016\/J.PHRS.2021.105467","journal-title":"Pharmacol Res"},{"issue":"19","key":"3266_CR9","doi-asserted-by":"publisher","first-page":"4527","DOI":"10.1242\/JCS.01320","volume":"117","author":"K Chen","year":"2004","unstructured":"Chen K, Ochalski PG, Tran TS, Sahir N, Schubert M, Pramatarova A, Howell BW (2004) Interaction between Dab1 and CrkII is promoted by Reelin signaling. J Cell Sci 117(19):4527\u20134536. https:\/\/doi.org\/10.1242\/JCS.01320","journal-title":"J Cell Sci"},{"issue":"32","key":"3266_CR10","doi-asserted-by":"publisher","first-page":"18961","DOI":"10.1074\/jbc.270.32.18961","volume":"270","author":"TY Chou","year":"1995","unstructured":"Chou TY, Hart GW, Dang CV (1995) c-Myc is glycosylated at threonine 58, a known phosphorylation site and a mutational hot spot in lymphomas. J Biol Chem 270(32):18961\u201318965. https:\/\/doi.org\/10.1074\/jbc.270.32.18961","journal-title":"J Biol Chem"},{"issue":"12","key":"3266_CR11","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/S0968-0004(00)01712-6","volume":"25","author":"P Cohen","year":"2000","unstructured":"Cohen P (2000) The regulation of protein function by multisite phosphorylation\u2014a 25 year update. Trends Biochem Sci 25(12):596\u2013601. https:\/\/doi.org\/10.1016\/S0968-0004(00)01712-6","journal-title":"Trends Biochem Sci"},{"issue":"6","key":"3266_CR12","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1007\/S00427-005-0052-5","volume":"216","author":"A Costagli","year":"2006","unstructured":"Costagli A, Felice B, Guffanti A, Wilson SW, Mione M (2006) Identification of alternatively spliced dab1 isoforms in zebrafish. Dev Genes Evol 216(6):291. https:\/\/doi.org\/10.1007\/S00427-005-0052-5","journal-title":"Dev Genes Evol"},{"issue":"17","key":"3266_CR13","doi-asserted-by":"publisher","first-page":"6580","DOI":"10.2741\/3175","volume":"13","author":"F Diella","year":"2008","unstructured":"Diella F, Haslam N, Chica C, Budd A, Michael S, Brown NP, Trav\u00e9 G, Gibson TJ (2008) Understanding eukaryotic linear motifs and their role in cell signaling and regulation. Front Biosci 13(17):6580\u20136603. https:\/\/doi.org\/10.2741\/3175","journal-title":"Front Biosci"},{"issue":"8","key":"3266_CR14","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1016\/S0969-2126(03)00134-5","volume":"11","author":"A Farooq","year":"2003","unstructured":"Farooq A, Zeng L, Yan KS, Ravichandran KS, Zhou MM (2003) Coupling of folding and binding in the PTB domain of the signaling protein Shc. Structure 11(8):905\u2013913. https:\/\/doi.org\/10.1016\/S0969-2126(03)00134-5","journal-title":"Structure"},{"key":"3266_CR15","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/J.NEUROPHARM.2012.08.015","volume":"68","author":"TD Folsom","year":"2013","unstructured":"Folsom TD, Fatemi SH (2013) The involvement of Reelin in neurodevelopmental disorders. Neuropharmacology 68:122\u2013135. https:\/\/doi.org\/10.1016\/J.NEUROPHARM.2012.08.015","journal-title":"Neuropharmacology"},{"issue":"13","key":"3266_CR16","doi-asserted-by":"publisher","first-page":"2319","DOI":"10.1007\/S00018-012-1171-6","volume":"70","author":"Z Gao","year":"2013","unstructured":"Gao Z, Godbout R (2013) Reelin-Disabled-1 signaling in neuronal migration: splicing takes the stage. Cell Mol Life Sci 70(13):2319. https:\/\/doi.org\/10.1007\/S00018-012-1171-6","journal-title":"Cell Mol Life Sci"},{"issue":"13","key":"3266_CR17","doi-asserted-by":"publisher","first-page":"9838","DOI":"10.1074\/JBC.M010420200","volume":"276","author":"Y Gao","year":"2001","unstructured":"Gao Y, Wells L, Comer FI, Parker GJ, Hart GW (2001) Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic \u03b2-N-acetylglucosaminidase from human brain. J Biol Chem 276(13):9838\u20139845. https:\/\/doi.org\/10.1074\/JBC.M010420200","journal-title":"J Biol Chem"},{"issue":"14","key":"3266_CR18","doi-asserted-by":"publisher","first-page":"2794","DOI":"10.1128\/MCB.00570-12","volume":"32","author":"Z Gao","year":"2012","unstructured":"Gao Z, Poon HY, Li L, Li X, Palmesino E, Glubrecht DD, Colwill K, Dutta I, Kania A, Pawson T, Godbout R (2012) Splice-mediated motif switching regulates disabled-1 phosphorylation and SH2 domain interactions. Mol Cell Biol 32(14):2794. https:\/\/doi.org\/10.1128\/MCB.00570-12","journal-title":"Mol Cell Biol"},{"issue":"4","key":"3266_CR19","doi-asserted-by":"publisher","first-page":"765","DOI":"10.1016\/J.BIOCEL.2004.12.001","volume":"37","author":"C Guinez","year":"2005","unstructured":"Guinez C, Morelle W, Michalski JC, Lefebvre T (2005) O-GlcNAc glycosylation: a signal for the nuclear transport of cytosolic proteins? Int J Biochem Cell Biol 37(4):765\u2013774. https:\/\/doi.org\/10.1016\/J.BIOCEL.2004.12.001","journal-title":"Int J Biochem Cell Biol"},{"doi-asserted-by":"crossref","unstructured":"Gupta R, Brunak S (2001) Prediction of glycosylation across the human proteome and the correlation to protein function","key":"3266_CR20","DOI":"10.1142\/9789812799623_0029"},{"issue":"2","key":"3266_CR21","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1016\/J.CMET.2014.07.014","volume":"20","author":"S Hardivill\u00e9","year":"2014","unstructured":"Hardivill\u00e9 S, Hart GW (2014) Nutrient regulation of signaling, transcription, and cell physiology by O-GlcNAcylation. Cell Metab 20(2):208\u2013213. https:\/\/doi.org\/10.1016\/J.CMET.2014.07.014","journal-title":"Cell Metab"},{"key":"3266_CR22","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1146\/ANNUREV.BIOCHEM.66.1.315","volume":"66","author":"GW Hart","year":"1997","unstructured":"Hart GW (1997) Dynamic O-linked glycosylation of nuclear and cytoskeletal proteins. Annu Rev Biochem 66:315\u2013335. https:\/\/doi.org\/10.1146\/ANNUREV.BIOCHEM.66.1.315","journal-title":"Annu Rev Biochem"},{"key":"3266_CR23","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1146\/ANNUREV-BIOCHEM-060608-102511","volume":"80","author":"GW Hart","year":"2011","unstructured":"Hart GW, Slawson C, Ramirez-Correa G, Lagerlof O (2011) Cross talk between O-GlcNAcylation and phosphorylation: roles in signaling, transcription, and chronic disease. Annu Rev Biochem 80:825. https:\/\/doi.org\/10.1146\/ANNUREV-BIOCHEM-060608-102511","journal-title":"Annu Rev Biochem"},{"issue":"2","key":"3266_CR24","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/S0896-6273(00)80861-2","volume":"24","author":"T Hiesberger","year":"1999","unstructured":"Hiesberger T, Trommsdorff M, Howell BW, Goffinet A, Mumby MC, Cooper JA, Herz J (1999) Direct binding of Reelin to VLDL receptor and ApoE receptor 2 induces tyrosine phosphorylation of disabled-1 and modulates tau phosphorylation. Neuron 24(2):481\u2013489. https:\/\/doi.org\/10.1016\/S0896-6273(00)80861-2","journal-title":"Neuron"},{"issue":"50","key":"3266_CR25","doi-asserted-by":"publisher","first-page":"38951","DOI":"10.1074\/JBC.M609061200","volume":"281","author":"T Honda","year":"2006","unstructured":"Honda T, Nakajima K (2006) Mouse disabled1 (DAB1) is a nucleocytoplasmic shuttling protein. J Biol Chem 281(50):38951\u201338965. https:\/\/doi.org\/10.1074\/JBC.M609061200","journal-title":"J Biol Chem"},{"issue":"1","key":"3266_CR26","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1016\/J.BBRC.2004.04.023","volume":"318","author":"Y Huang","year":"2004","unstructured":"Huang Y, Magdaleno S, Hopkins R, Slaughter C, Curran T, Keshvara L (2004) Tyrosine phosphorylated Disabled 1 recruits Crk family adapter proteins. Biochem Biophys Res Commun 318(1):204\u2013212. https:\/\/doi.org\/10.1016\/J.BBRC.2004.04.023","journal-title":"Biochem Biophys Res Commun"},{"issue":"6","key":"3266_CR27","doi-asserted-by":"publisher","first-page":"1635","DOI":"10.1093\/MOLBEV\/MSW046","volume":"33","author":"J Huerta-Cepas","year":"2016","unstructured":"Huerta-Cepas J, Serra F, Bork P (2016) ETE 3: reconstruction, analysis, and visualization of phylogenomic data. Mol Biol Evol 33(6):1635\u20131638. https:\/\/doi.org\/10.1093\/MOLBEV\/MSW046","journal-title":"Mol Biol Evol"},{"issue":"8","key":"3266_CR28","doi-asserted-by":"publisher","first-page":"1878","DOI":"10.1038\/SJ.EMBOJ.7600185","volume":"23","author":"S Katyal","year":"2004","unstructured":"Katyal S, Godbout R (2004) Alternative splicing modulates Disabled-1 (Dab1) function in the developing chick retina. EMBO J 23(8):1878\u20131888. https:\/\/doi.org\/10.1038\/SJ.EMBOJ.7600185","journal-title":"EMBO J"},{"issue":"2","key":"3266_CR29","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/J.JMB.2007.01.068","volume":"368","author":"S Katyal","year":"2007","unstructured":"Katyal S, Gao Z, Monckton E, Glubrecht D, Godbout R (2007) Hierarchical disabled-1 tyrosine phosphorylation in Src family kinase activation and neurite formation. J Mol Biol 368(2):349. https:\/\/doi.org\/10.1016\/J.JMB.2007.01.068","journal-title":"J Mol Biol"},{"issue":"19","key":"3266_CR30","doi-asserted-by":"publisher","first-page":"16008","DOI":"10.1074\/JBC.M101422200","volume":"276","author":"L Keshvara","year":"2001","unstructured":"Keshvara L, Benhayon D, Magdaleno S, Curran T (2001) Identification of Reelin-induced sites of tyrosyl phosphorylation on disabled 1. J Biol Chem 276(19):16008\u201316014. https:\/\/doi.org\/10.1074\/JBC.M101422200","journal-title":"J Biol Chem"},{"issue":"35","key":"3266_CR31","doi-asserted-by":"publisher","first-page":"E7255","DOI":"10.1073\/PNAS.1620529114\/SUPPL_FILE\/PNAS.1620529114.SAPP.PDF","volume":"114","author":"AC Leney","year":"2017","unstructured":"Leney AC, el Atmioui D, Wu W, Ovaa H, Heck AJR (2017) Elucidating crosstalk mechanisms between phosphorylation and O-GlcNAcylation. Proc Natl Acad Sci USA 114(35):E7255\u2013E7261. https:\/\/doi.org\/10.1073\/PNAS.1620529114\/SUPPL_FILE\/PNAS.1620529114.SAPP.PDF","journal-title":"Proc Natl Acad Sci USA"},{"key":"3266_CR32","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/1471-2202-12-17","volume":"12","author":"H Long","year":"2011","unstructured":"Long H, Bock HH, Lei T, Chai X, Yuan J, Herz J, Frotscher M, Yang Z (2011) Identification of alternatively spliced Dab1 and Fyn isoforms in pig. BMC Neurosci 12:17. https:\/\/doi.org\/10.1186\/1471-2202-12-17","journal-title":"BMC Neurosci"},{"issue":"W1","key":"3266_CR33","doi-asserted-by":"publisher","first-page":"W276","DOI":"10.1093\/NAR\/GKAC240","volume":"50","author":"F Madeira","year":"2022","unstructured":"Madeira F, Pearce M, Tivey ARN, Basutkar P, Lee J, Edbali O, Madhusoodanan N, Kolesnikov A, Lopez R (2022) Search and sequence analysis tools services from EMBL-EBI in 2022. Nucleic Acids Res 50(W1):W276\u2013W279. https:\/\/doi.org\/10.1093\/NAR\/GKAC240","journal-title":"Nucleic Acids Res"},{"issue":"34","key":"3266_CR34","doi-asserted-by":"publisher","first-page":"35313","DOI":"10.1074\/jbc.m404133200","volume":"279","author":"S Marshall","year":"2004","unstructured":"Marshall S, Nadeau O, Yamasaki K (2004) Dynamic actions of glucose and glucosamine on hexosamine biosynthesis in isolated adipocytes. J Biol Chem 279(34):35313\u201335319. https:\/\/doi.org\/10.1074\/jbc.m404133200","journal-title":"J Biol Chem"},{"key":"3266_CR35","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1002\/PROT.25360","volume":"86","author":"LJ McGuffin","year":"2018","unstructured":"McGuffin LJ, Shuid AN, Kempster R, Maghrabi AHA, Nealon JO, Salehe BR, Atkins JD, Roche DB (2018) Accurate template-based modeling in CASP12 using the IntFOLD4-TS, ModFOLD6, and ReFOLD methods. Proteins: Struct, Funct, Bioinf 86:335\u2013344. https:\/\/doi.org\/10.1002\/PROT.25360","journal-title":"Proteins: Struct, Funct, Bioinf"},{"issue":"1","key":"3266_CR36","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-021-25316-w","volume":"12","author":"SM Mortuza","year":"2021","unstructured":"Mortuza SM, Zheng W, Zhang C, Li Y, Pearce R, Zhang Y (2021) Improving fragment-based ab initio protein structure assembly using low-accuracy contact-map predictions. Nat Commun 12(1):1\u201312. https:\/\/doi.org\/10.1038\/s41467-021-25316-w","journal-title":"Nat Commun"},{"issue":"5","key":"3266_CR37","doi-asserted-by":"publisher","first-page":"437","DOI":"10.1631\/JZUS.B1900150","volume":"20","author":"H Nie","year":"2019","unstructured":"Nie H, Yi W (2019) O-GlcNAcylation, a sweet link to the pathology of diseases. J Zhejiang Univ Sci B 20(5):437\u2013448. https:\/\/doi.org\/10.1631\/JZUS.B1900150","journal-title":"J Zhejiang Univ Sci B"},{"key":"3266_CR38","doi-asserted-by":"publisher","DOI":"10.3389\/FGENE.2014.00270","author":"H Nishi","year":"2014","unstructured":"Nishi H, Shaytan A, Panchenko AR (2014) Physicochemical mechanisms of protein regulation by phosphorylation. Front Genet. https:\/\/doi.org\/10.3389\/FGENE.2014.00270","journal-title":"Front Genet"},{"issue":"2","key":"3266_CR39","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/S12017-019-08584-0","volume":"22","author":"J Park","year":"2020","unstructured":"Park J, Lai MKP, Arumugam TV, Jo DG (2020) O-GlcNAcylation as a therapeutic target for Alzheimer\u2019s disease. NeuroMol Med 22(2):171\u2013193. https:\/\/doi.org\/10.1007\/S12017-019-08584-0","journal-title":"NeuroMol Med"},{"issue":"15","key":"3266_CR40","doi-asserted-by":"publisher","first-page":"2460","DOI":"10.1093\/BIOINFORMATICS\/BTH248","volume":"20","author":"AA Porollo","year":"2004","unstructured":"Porollo AA, Adamczak R, Meller J (2004) POLYVIEW: a flexible visualization tool for structural and functional annotations of proteins. Bioinformatics (oxford, England) 20(15):2460\u20132462. https:\/\/doi.org\/10.1093\/BIOINFORMATICS\/BTH248","journal-title":"Bioinformatics (oxford, England)"},{"issue":"20","key":"3266_CR41","doi-asserted-by":"publisher","first-page":"7210","DOI":"10.1128\/MCB.23.20.7210-7221.2003\/FORMAT\/EPUB","volume":"23","author":"A Pramatarova","year":"2003","unstructured":"Pramatarova A, Ochalski PG, Chen K, Gropman A, Myers S, Min K-T, Howell BW (2003) Nck\u03b2 interacts with tyrosine-phosphorylated disabled 1 and redistributes in Reelin-stimulated neurons. Mol Cell Biol 23(20):7210\u20137221. https:\/\/doi.org\/10.1128\/MCB.23.20.7210-7221.2003\/FORMAT\/EPUB","journal-title":"Mol Cell Biol"},{"key":"3266_CR42","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1146\/ANNUREV.NEURO.24.1.1005","volume":"24","author":"DS Rice","year":"2003","unstructured":"Rice DS, Curran T (2003) Role of the Reelin signaling pathway in central nervous system development. Annu Rev Neurosci 24:1005\u20131039. https:\/\/doi.org\/10.1146\/ANNUREV.NEURO.24.1.1005","journal-title":"Annu Rev Neurosci"},{"unstructured":"Schrodinger LLC (2015) The PyMOL Molecular Graphics System, Version 1.8","key":"3266_CR43"},{"issue":"1","key":"3266_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/srep34614","volume":"6","author":"HG Seo","year":"2016","unstructured":"Seo HG, Kim HB, Kang MJ, Ryum JH, Yi EC, Cho JW (2016) Identification of the nuclear localisation signal of O-GlcNAc transferase and its nuclear import regulation. Sci Rep 6(1):1\u201312. https:\/\/doi.org\/10.1038\/srep34614","journal-title":"Sci Rep"},{"issue":"1","key":"3266_CR45","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1021\/acs.biochem.7b00871","volume":"57","author":"HJ Tarbet","year":"2018","unstructured":"Tarbet HJ, Toleman CA, Boyce M (2018) A sweet embrace: control of protein-protein interactions by O-linked \u03b2-N-Acetylglucosamine. Biochemistry 57(1):13\u201321. https:\/\/doi.org\/10.1021\/acs.biochem.7b00871","journal-title":"Biochemistry"},{"issue":"2","key":"3266_CR46","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.tibs.2010.09.006","volume":"36","author":"SS Taylor","year":"2011","unstructured":"Taylor SS, Kornev AP (2011) Protein kinases: evolution of dynamic regulatory proteins. Trends Biochem Sci 36(2):65\u201377. https:\/\/doi.org\/10.1016\/j.tibs.2010.09.006","journal-title":"Trends Biochem Sci"},{"issue":"6220","key":"3266_CR47","doi-asserted-by":"publisher","first-page":"1260419","DOI":"10.1126\/SCIENCE.1260419\/SUPPL_FILE\/1260419_UHLEN.SM.PDF","volume":"347","author":"M Uhl\u00e9n","year":"2015","unstructured":"Uhl\u00e9n M, Fagerberg L, Hallstr\u00f6m BM, Lindskog C, Oksvold P, Mardinoglu A, Sivertsson \u00c5, Kampf C, Sj\u00f6stedt E, Asplund A, Olsson IM, Edlund K, Lundberg E, Navani S, Szigyarto CAK, Odeberg J, Djureinovic D, Takanen JO, Hober S et al (2015) Tissue-based map of the human proteome. Science 347(6220):1260419. https:\/\/doi.org\/10.1126\/SCIENCE.1260419\/SUPPL_FILE\/1260419_UHLEN.SM.PDF","journal-title":"Science"},{"issue":"17","key":"3266_CR48","doi-asserted-by":"publisher","first-page":"3152","DOI":"10.1111\/FEBS.14491","volume":"285","author":"SAM van der Laarse","year":"2018","unstructured":"van der Laarse SAM, Leney AC, Heck AJR (2018) Crosstalk between phosphorylation and O-GlcNAcylation: friend or foe. FEBS J 285(17):3152\u20133167. https:\/\/doi.org\/10.1111\/FEBS.14491","journal-title":"FEBS J"},{"issue":"13","key":"3266_CR49","doi-asserted-by":"publisher","first-page":"4888","DOI":"10.1128\/MCB.20.13.4888-4899.2000","volume":"20","author":"E Vielhaber","year":"2000","unstructured":"Vielhaber E, Eide E, Rivers A, Gao Z-H, Virshup DM (2000) Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I \u025b. Mol Cell Biol 20(13):4888. https:\/\/doi.org\/10.1128\/MCB.20.13.4888-4899.2000","journal-title":"Mol Cell Biol"},{"doi-asserted-by":"crossref","unstructured":"Wang Z, Gucek M, Hart GW (2008) Cross-talk between GlcNAcylation and phosphorylation: site-specific phosphorylation dynamics in response to globally elevated O-GlcNAc. www.pnas.org\/cgi\/content\/full\/","key":"3266_CR50","DOI":"10.1073\/pnas.0806216105"},{"key":"3266_CR51","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1016\/J.BRAINRESBULL.2016.08.002","volume":"133","author":"WY Wani","year":"2017","unstructured":"Wani WY, Chatham JC, Darley-Usmar V, McMahon LL, Zhang J (2017) O-GlcNAcylation and neurodegeneration. Brain Res Bull 133:80\u201387. https:\/\/doi.org\/10.1016\/J.BRAINRESBULL.2016.08.002","journal-title":"Brain Res Bull"},{"issue":"5512","key":"3266_CR52","doi-asserted-by":"publisher","first-page":"2376","DOI":"10.1126\/SCIENCE.1058714","volume":"291","author":"L Wells","year":"2001","unstructured":"Wells L, Vosseller K, Hart GW (2001) Glycosylation of nucleocytoplasmic proteins: signal transduction and O-GlcNAc. Science 291(5512):2376\u20132378. https:\/\/doi.org\/10.1126\/SCIENCE.1058714","journal-title":"Science"},{"issue":"3","key":"3266_CR53","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1007\/S00726-010-0709-X\/FIGURES\/4","volume":"40","author":"L Wells","year":"2011","unstructured":"Wells L, Slawson C, Hart GW (2011) The E2F\u20131 associated retinoblastoma-susceptibility gene product is modified by O-GlcNAc. Amino Acids 40(3):877\u2013883. https:\/\/doi.org\/10.1007\/S00726-010-0709-X\/FIGURES\/4","journal-title":"Amino Acids"},{"issue":"7","key":"3266_CR54","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.1002\/PROT.24065","volume":"80","author":"D Xu","year":"2012","unstructured":"Xu D, Zhang Y (2012) Ab initio protein structure assembly using continuous structure fragments and optimized knowledge-based force field. Proteins: Struct, Funct, Bioinf 80(7):1715\u20131735. https:\/\/doi.org\/10.1002\/PROT.24065","journal-title":"Proteins: Struct, Funct, Bioinf"},{"issue":"7","key":"3266_CR55","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1038\/nrm.2017.22","volume":"18","author":"X Yang","year":"2017","unstructured":"Yang X, Qian K (2017) Protein O-GlcNAcylation: emerging mechanisms and functions. Nat Rev Mol Cell Biol 18(7):452\u2013465. https:\/\/doi.org\/10.1038\/nrm.2017.22","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"10","key":"3266_CR56","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.1038\/ncb1470","volume":"8","author":"WH Yang","year":"2006","unstructured":"Yang WH, Kim JE, Nam HW, Ju JW, Kim HS, Kim YS, Cho JW (2006) Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability. Nat Cell Biol 8(10):1074\u20131083. https:\/\/doi.org\/10.1038\/ncb1470","journal-title":"Nat Cell Biol"},{"issue":"38","key":"3266_CR57","doi-asserted-by":"publisher","first-page":"36572","DOI":"10.1074\/JBC.M304384200","volume":"278","author":"M Yun","year":"2003","unstructured":"Yun M, Keshvara L, Park CG, Zhang YM, Bradley Dickerson J, Zheng J, Rock CO, Curran T, Park HW (2003) Crystal structures of the dab homology domains of mouse disabled 1 and 2. J Biol Chem 278(38):36572\u201336581. https:\/\/doi.org\/10.1074\/JBC.M304384200","journal-title":"J Biol Chem"},{"issue":"4","key":"3266_CR58","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1038\/nchembio.797","volume":"8","author":"SA Yuzwa","year":"2012","unstructured":"Yuzwa SA, Shan X, MacAuley MS, Clark T, Skorobogatko Y, Vosseller K, Vocadlo DJ (2012) Increasing O-GlcNAc slows neurodegeneration and stabilizes tau against aggregation. Nat Chem Biol 8(4):393\u2013399. https:\/\/doi.org\/10.1038\/nchembio.797","journal-title":"Nat Chem Biol"},{"issue":"1\u20132","key":"3266_CR59","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/J.BBAGEN.2004.03.016","volume":"1673","author":"NE Zachara","year":"2004","unstructured":"Zachara NE, Hart GW (2004) O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress. Biochimica Et Biophysica Acta (BBA) - General Subjects 1673(1\u20132):13\u201328. https:\/\/doi.org\/10.1016\/J.BBAGEN.2004.03.016","journal-title":"Biochimica Et Biophysica Acta (BBA) - General Subjects"},{"issue":"10","key":"3266_CR60","doi-asserted-by":"publisher","first-page":"3457","DOI":"10.1093\/CERCOR\/BHX212","volume":"28","author":"B Zhang","year":"2018","unstructured":"Zhang B, Wang W, Zhang Z, Hu Y, Meng F, Wang F, Lou H, Zhu L, Godbout R, Duan S, Gao Z (2018) Alternative splicing of disabled-1 controls multipolar-to-bipolar transition of migrating neurons in the neocortex. Cereb Cortex 28(10):3457\u20133467. https:\/\/doi.org\/10.1093\/CERCOR\/BHX212","journal-title":"Cereb Cortex"},{"issue":"5","key":"3266_CR61","doi-asserted-by":"publisher","first-page":"767","DOI":"10.1016\/0092-8674(93)90404-E","volume":"72","author":"S Zhou","year":"1993","unstructured":"Zhou S, Shoelson SE, Chaudhuri M, Gish G, Pawson T, Haser WG, King F, Roberts T, Ratnofsky S, Lechleider RJ, Neel BG, Birge RB, Fajardo JE, Chou MM, Hanafusa H, Schaffhausen B, Cantley LC (1993) SH2 domains recognize specific phosphopeptide sequences. Cell 72(5):767\u2013778. https:\/\/doi.org\/10.1016\/0092-8674(93)90404-E","journal-title":"Cell"},{"key":"3266_CR62","doi-asserted-by":"publisher","first-page":"100885","DOI":"10.1016\/J.MAM.2020.100885","volume":"79","author":"Y Zhu","year":"2021","unstructured":"Zhu Y, Hart GW (2021) Targeting O-GlcNAcylation to develop novel therapeutics. Mol Aspects Med 79:100885. https:\/\/doi.org\/10.1016\/J.MAM.2020.100885","journal-title":"Mol Aspects Med"}],"container-title":["Amino Acids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-023-03266-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00726-023-03266-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00726-023-03266-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T06:01:00Z","timestamp":1687500060000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00726-023-03266-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,17]]},"references-count":62,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["3266"],"URL":"https:\/\/doi.org\/10.1007\/s00726-023-03266-5","relation":{},"ISSN":["0939-4451","1438-2199"],"issn-type":[{"type":"print","value":"0939-4451"},{"type":"electronic","value":"1438-2199"}],"subject":[],"published":{"date-parts":[[2023,4,17]]},"assertion":[{"value":"13 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 April 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 April 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflict of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}