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These women, residing in urban areas of Thailand such as Bangkok, Nonthaburi, Nakhon Pathom, Pathum Thani, Samut Prakan, and Samut Sakhon, completed a survey questionnaire with the assistance of health volunteers during the COVID-19 pandemic, between October 2021 and April 2022. The study revealed that 55.85% of participants reported experiencing poor quality of life (QOL) during the pandemic. Stepwise logistic regression analysis identified several significant associations with QOL. Factors linked to a poorer QOL included lower levels of well-being index (odds ratio [OR] 7.89, 95% confidence interval [CI] 3.16\u201319.75, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), reduced physical activity (OR 2.72, 95% CI 1.62\u20134.54, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), and the severity of menopausal symptoms (OR 1.94, 95% CI 1.42\u20132.66, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Conversely, higher education (OR 0.28, 95% CI 0.10\u20130.75, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), an earlier onset of menopause (OR 0.55, 95% CI 0.39\u20130.78, <jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01), and occasional social alcohol consumption (OR 0.56, 95% CI 0.33\u20130.94, <jats:italic>P<\/jats:italic>\u2009=\u20090.03) were identified as protective factors for QOL.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>These findings highlight the importance of comprehensive menopausal care, addressing both physical and mental well-being, and providing specific care for menopausal symptoms during challenging times of the COVID-19 pandemic.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00737-025-01581-2","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T12:05:06Z","timestamp":1743768306000},"page":"1181-1190","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Quality of life and the associated factors among postmenopausal women during the COVID-19 pandemic: a cross-sectional study"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5343-3297","authenticated-orcid":false,"given":"Sakda Arj-Ong","family":"Vallibhakara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nichakorn","family":"Piyatham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9980-007X","authenticated-orcid":false,"given":"Orawin","family":"Vallibhakara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5302-4370","authenticated-orcid":false,"given":"Jittima","family":"Manonai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,3]]},"reference":[{"issue":"1","key":"1581_CR1","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1186\/s12905-021-01361-x","volume":"21","author":"M Barati","year":"2021","unstructured":"Barati M, Akbari-Heidari H, Samadi-Yaghin E, Jenabi E, Jormand H, Kamyari N (2021) The factors associated with the quality of life among postmenopausal women. 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