{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:59:23Z","timestamp":1783990763274,"version":"3.55.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2008,2,27]],"date-time":"2008-02-27T00:00:00Z","timestamp":1204070400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Bone Miner Metab"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1007\/s00774-007-0802-8","type":"journal-article","created":{"date-parts":[[2008,2,26]],"date-time":"2008-02-26T18:41:57Z","timestamp":1204051317000},"page":"115-122","source":"Crossref","is-referenced-by-count":34,"title":["Present status of and future direction for articular cartilage repair"],"prefix":"10.1007","volume":"26","author":[{"given":"Shigeyuki","family":"Wakitani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amu","family":"Kawaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshio","family":"Tokuhara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunio","family":"Takaoka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,2,27]]},"reference":[{"key":"802_CR1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1056\/NEJM199410063311401","volume":"331","author":"M. Brittberg","year":"1994","unstructured":"Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L (1994) Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331:889\u2013895","journal-title":"N Engl J Med"},{"key":"802_CR2","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1053\/jars.2003.50112","volume":"19","author":"J.R. Steadman","year":"2003","unstructured":"Steadman JR, Briggs KK, Rodrigo JJ, Kocher MS, Gill TJ, Rodkey WG (2003) Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy 19:477\u2013484","journal-title":"Arthroscopy"},{"key":"802_CR3","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0749-8063(05)80428-1","volume":"9","author":"Y. Matsusue","year":"1993","unstructured":"Matsusue Y, Yamamuro T, Hama H (1993) Arthroscopic multiple osteochondral transplantation to the chondral defect in the knee associated with anterior cruciate ligament disruption. Arthroscopy 9:318\u2013321","journal-title":"Arthroscopy"},{"key":"802_CR4","doi-asserted-by":"crossref","first-page":"65","DOI":"10.2106\/00004623-200400001-00009","volume":"86","author":"L. Hangody","year":"2004","unstructured":"Hangody L, Rathonyi GK, Duska Z, Vasarhelyi G, Fules P, Modis L (2004) Autologous osteochondral mosaicplasty. Surgical technique. J Bone Joint Surg [Am] 86:65\u201372","journal-title":"J Bone Joint Surg [Am]"},{"key":"802_CR5","doi-asserted-by":"crossref","first-page":"579","DOI":"10.2106\/00004623-199404000-00013","volume":"76","author":"S. Wakitani","year":"1994","unstructured":"Wakitani S, Goto T, Pineda SJ, Young RG, Mansour JM, Caplan AI, Goldberg VM (1994) Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage. J Bone Joint Surg [Am] 76:579\u2013592","journal-title":"J Bone Joint Surg [Am]"},{"key":"802_CR6","doi-asserted-by":"crossref","first-page":"595","DOI":"10.3727\/000000004783983747","volume":"13","author":"S. Wakitani","year":"2004","unstructured":"Wakitani S, Mitsuoka T, Nakamura N, Toritsuka Y, Nakamura Y, Horibe S (2004) Autologous bone marrow stromal cell transplantation for repair of full-thickness articular cartilage defects in human patellae: two case reports. Cell Transplant 13:595\u2013600","journal-title":"Cell Transplant"},{"key":"802_CR7","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1053\/joca.2001.0504","volume":"10","author":"S. Wakitani","year":"2002","unstructured":"Wakitani S, Imoto K, Yamamoto T, Saito M, Murata N, Yoneda M (2002) Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthritis Cartilage 10:199\u2013206","journal-title":"Osteoarthritis Cartilage"},{"key":"802_CR8","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1002\/term.8","volume":"1","author":"S. Wakitani","year":"2997","unstructured":"Wakitani S, Nawata M, Tensho K, Okabe Y, Machida H, Ohgushi H (2997) Repair of articular cartilage defects in the patello-femoral joint with autologous bone marrow mesenchymal cell transplantation: three case reports involving 9 defects in 5 knees. J Tissue Eng Regen Med 1:74\u201379","journal-title":"J Tissue Eng Regen Med"},{"key":"802_CR9","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S0092-8674(01)00222-7","volume":"104","author":"C. Hartmann","year":"2001","unstructured":"Hartmann C, Tabin CJ (2001) Wnt-14 plays a pivotal role in inducing synovial joint formation in the developing appendicular skeleton. Cell 104:341\u2013351","journal-title":"Cell"},{"key":"802_CR10","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1098\/rstl.1742.0079","volume":"42","author":"W. Hunter","year":"1743","unstructured":"Hunter W (1743) Of the structure and disease of articular cartilages. Philos Trans Lond 42:514\u2013521","journal-title":"Philos Trans Lond"},{"key":"802_CR11","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1053\/joca.2002.0801","volume":"10","author":"E.B. Hunziker","year":"2002","unstructured":"Hunziker EB (2002) Articular cartilage repair: basic science and clinical progress. A review of the current status and prospective. Osteoarthritis Cartilage 10:432\u2013463","journal-title":"Osteoarthritis Cartilage"},{"key":"802_CR12","doi-asserted-by":"crossref","first-page":"523","DOI":"10.3109\/17453679608996682","volume":"67","author":"K. Messner","year":"1996","unstructured":"Messner K, Gillquist J (1996) Cartilage repair. A critical review. Acta Orthop Scand 67:523\u2013529","journal-title":"Acta Orthop Scand"},{"issue":"suppl2","key":"802_CR13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.2106\/00004623-200300002-00002","volume":"85","author":"K.D. Shelbourne","year":"2003","unstructured":"Shelbourne KD, Jari S, Gray T (2003) Outcome of untreated traumatic articular cartilage defects of the knee: a natural history study. J. Bone Joint Surg [Am] 85(suppl 2):8\u201316","journal-title":"J. Bone Joint Surg [Am]"},{"key":"802_CR14","first-page":"618","volume":"41","author":"K.H. Pridie","year":"1959","unstructured":"Pridie KH (1959) A method of resurfacing osteoarthritic knee joints. J Bone Joint Surg [Br] 41:618\u2013619","journal-title":"J Bone Joint Surg [Br]"},{"key":"802_CR15","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0749-8063(86)80012-3","volume":"2","author":"L.L. Johnson","year":"1986","unstructured":"Johnson LL (1986) Arthroscopic abrasion arthroplasty historical and pathologic perspective: present status. Arthroscopy 2:54\u201369","journal-title":"Arthroscopy"},{"key":"802_CR16","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1302\/0301-620X.50B1.184","volume":"50","author":"P.J. Chesterman","year":"1968","unstructured":"Chesterman PJ, Smith AU (1968) Homotransplantation of articular cartilage and isolated chondrocytes. J Bone Joint Surg [Br] 50:184\u2013197","journal-title":"J Bone Joint Surg [Br]"},{"key":"802_CR17","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1038\/230385a0","volume":"230","author":"G. Bentley","year":"1971","unstructured":"Bentley G, Greer RBI (1971) Homotransplantation of isolated epiphyseal articular cartilage chondrocytes into joint surfaces of rabbits. Nature (Lond) 230:385\u2013388","journal-title":"Nature (Lond)"},{"key":"802_CR18","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1302\/0301-620X.68B1.3941138","volume":"68","author":"J.E. Aston","year":"1986","unstructured":"Aston JE, Bentley G (1986) Repair of articular surfaces by allografts of articular and growth-plate cartilage. J Bone Joint Surg [Br] 68:29\u201335","journal-title":"J Bone Joint Surg [Br]"},{"key":"802_CR19","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1302\/0301-620X.71B1.2915011","volume":"71","author":"S. Wakitani","year":"1989","unstructured":"Wakitani S, Kimura T, Hirooka A, Ochi T, Yoneda M, Yasui N, Owaki H, Ono K (1989) Repair of rabbit articular surfaces with allograft chondrocytes embedded in collagen gel. J Bone Joint Surg Br 71:74\u201380","journal-title":"J Bone Joint Surg Br"},{"key":"802_CR20","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1089\/ten.1998.4.429","volume":"4","author":"S. Wakitani","year":"1998","unstructured":"Wakitani S, Goto T, Young RG, Mansour JM, Goldberg VM, Caplan AI (1998) Repair of large full-thickness articular cartilage defects with allograft articular chondrocytes embedded in a collagen gel. Tissue Eng 4:429\u2013444","journal-title":"Tissue Eng"},{"key":"802_CR21","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3109\/17453679809002358","volume":"69","author":"S. Kawamura","year":"1998","unstructured":"Kawamura S, Wakitani S, Kimura T, Maeda A, Caplan AI, Shino K, Ochi T (1998) Articular cartilage repair. Rabbit experiments with a collagen gel-biomatrix and chondrocytes cultured in it. Acta Orthop Scand 69:56\u201362","journal-title":"Acta Orthop Scand"},{"key":"802_CR22","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1002\/jor.1100070208","volume":"7","author":"D.A. Grande","year":"1989","unstructured":"Grande DA, Pitman MI, Peterson L, Menche D, Klein M. (1989) The repair of experimentally produced defects in rabbit articular cartilage by autologous chondrocyte transplantation. J Orthop Res 7:208\u2013218","journal-title":"J Orthop Res"},{"key":"802_CR23","doi-asserted-by":"crossref","first-page":"185","DOI":"10.2106\/00004623-200302000-00001","volume":"85","author":"U. Horas","year":"2003","unstructured":"Horas U, Pelinkovic D, Herr G, Aigner T, Schnettler R (2003) Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint. A prospective, comparative trial. J Bone Joint Surg [Am] 85:185\u2013192","journal-title":"J Bone Joint Surg [Am]"},{"key":"802_CR24","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.2106\/00004623-200312000-00044","volume":"85","author":"G.D. Smith","year":"2003","unstructured":"Smith GD, Richardson JB, Brittberg M, Erggelet C, Verdonk R, Knutsen G, Ashton BA, Ashton IK, Harrison PE (2003) Letter to the editor. J Bone Joint Surg [Am] 85:2487\u20132488","journal-title":"J Bone Joint Surg [Am]"},{"key":"802_CR25","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1302\/0301-620X.85B2.13543","volume":"85","author":"G. Bentley","year":"2003","unstructured":"Bentley G, Biant LC, Carrington RWJ, Akmal M, Goldberg M, Williams AM, Skinner JA, Pringle J (2003) A prospective, randomized comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee. J Bone Joint Surg [Br] 85:223\u2013230","journal-title":"J Bone Joint Surg [Br]"},{"key":"802_CR26","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1302\/0301-620X.86B4.15329","volume":"86","author":"G. Kish","year":"2004","unstructured":"Kish G, Hangody L (2004) Letter to the editor. J Bone Joint Surg [Br] 86:619","journal-title":"J Bone Joint Surg [Br]"},{"key":"802_CR27","doi-asserted-by":"crossref","first-page":"455","DOI":"10.2106\/00004623-200403000-00001","volume":"86","author":"G. Knutsen","year":"2004","unstructured":"Knutsen G, Engebretsen L, Ludvigsen TC, Drogset JO, Grontvedt T, Solheim E, Strand T, Roberts S, Isaksen V, Johansen O (2004) Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial. J Bone Joint Surg [Am] 86:455\u2013464","journal-title":"J Bone Joint Surg [Am]"},{"key":"802_CR28","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1302\/0301-620X.84B4.11947","volume":"84","author":"M. Ochi","year":"2002","unstructured":"Ochi M, Uchio Y, Kawasaki K, Wakitani S, Iwasa J (2002) Transplantation of cartilage-like tissue made by tissue engineering in the treatment of cartilage defects of the knee. J Bone Joint Surg [Br] 84:571\u2013578","journal-title":"J Bone Joint Surg [Br]"},{"key":"802_CR29","first-page":"294","volume":"151","author":"B.A. Ashton","year":"1980","unstructured":"Ashton BA, Allen TD, Howlett CR, Eaglesom CC, Hattori A, Owen M (1980) Formation of bone and cartilage by marrow stromal cells in diffusion chambers in vivo. Clin Orthop 151: 294\u2013307","journal-title":"Clin Orthop"},{"key":"802_CR30","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1097\/00003086-199101000-00038","volume":"262","author":"J. Goshima","year":"1991","unstructured":"Goshima J, Goldberg VM, Caplan AI (1991) The osteogenic potential of culture-expanded rat marrow mesenchymal cells assayed in vivo in calcium phosphate ceramic blocks. Clin Orthop 262:298\u2013311","journal-title":"Clin Orthop"},{"key":"802_CR31","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1006\/excr.1997.3858","volume":"238","author":"B. Johnstone","year":"1998","unstructured":"Johnstone B, Hering TM, Caplan AI, Goldberg VM, Yoo JU (1998) In vitro chondrogenesis of bone marrow mesenchymal progenitor cells. Exp Cell Res 238:265\u2013272","journal-title":"Exp Cell Res"},{"key":"802_CR32","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1126\/science.284.5411.143","volume":"284","author":"M.F. Pittenger","year":"1999","unstructured":"Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284:143\u2013147","journal-title":"Science"},{"key":"802_CR33","doi-asserted-by":"crossref","first-page":"10711","DOI":"10.1073\/pnas.96.19.10711","volume":"96","author":"G.C. Kopen","year":"1999","unstructured":"Kopen GC, Prockop DJ, Phinney DG (1999) Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brain. Proc Natl Acad Sci U S A 96:10711\u201310716","journal-title":"Proc Natl Acad Sci U S A"},{"key":"802_CR34","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1126\/science.284.5417.1168","volume":"284","author":"B.E. Petersen","year":"1999","unstructured":"Petersen BE, Bowen WC, Patrene KD, Mars WM, Sullivan AK, Murase N, Boggs SS, Greenberger JS, Goff JP (1999) Bone marrow as a potential source of hepatic oval cells. Science 284:1168\u20131170","journal-title":"Science"},{"key":"802_CR35","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S0030-5898(20)30753-7","volume":"10","author":"Y. Fujisawa","year":"1979","unstructured":"Fujisawa Y, Masuhara K, Shiomi S (1979) The effect of high tibial osteotomy on osteoarthritis of the knee. An arthroscopic study of 54 knee joints. Orthop Clin N Am 10:585\u2013608","journal-title":"Orthop Clin N Am"},{"key":"802_CR36","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0749-8063(97)90204-8","volume":"13","author":"S. Akizuki","year":"1997","unstructured":"Akizuki S, Yasukawa Y, Takizawa T (1997) Does arthroscopic abrasion arthroplasty promote cartilage regeneration in osteoarthritic knees with eburnation. A prospective study of high tibial osteotomy with abrasion arthroplasty versus high tibial osteotomy alone. Arthroscopy 13:9\u201317","journal-title":"Arthroscopy"},{"key":"802_CR37","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1006\/bbrc.2001.4898","volume":"284","author":"I. Sekiya","year":"2001","unstructured":"Sekiya I, Colter DC, Prockop DJ (2001) BMP-6 enhances chondrogenesis in a subpopulation of human marrow stromal cells. Biochem Biophys Res Commun 284:411\u2013418","journal-title":"Biochem Biophys Res Commun"},{"key":"802_CR38","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.joca.2004.04.007","volume":"12","author":"T. Yamamoto","year":"2004","unstructured":"Yamamoto T, Wakitani S, Imoto K, Hattori T, Nakaya H, Saito M, Yonenobu K (2004) Fibroblast growth factor-2 promotes repair of partial thickness defects of immature rabbits. Osteoarthritis Cartilage 12:636\u2013641","journal-title":"Osteoarthritis Cartilage"},{"key":"802_CR39","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.bone.2004.11.010","volume":"36","author":"Y. Nakamura","year":"2005","unstructured":"Nakamura Y, Tensho K, Nakaya H, Okabe T, Wakitani S (2005) Biphasic effects of fibroblast growth factor-2 during bone morphogenetic protein-2 induced ectopic bone formation. Bone (NY) 36:399\u2013407","journal-title":"Bone (NY)"},{"key":"802_CR40","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1093\/rheumatology\/keh240","volume":"43","author":"R. Katayama","year":"2004","unstructured":"Katayama R, Wakitani S, Tsumaki N, Morita Y, Matsushita I, Gejo R, Kimura T (2004) Repair of articular cartilage defects in rabbits using CDMP1 gene-transfected autologous mesenchymal cells derived from bone marrow. Rheumatology (Oxf) 43:390\u2013395","journal-title":"Rheumatology (Oxf)"},{"key":"802_CR41","doi-asserted-by":"crossref","first-page":"3561","DOI":"10.1002\/art.20611","volume":"50","author":"T. Ikeda","year":"2004","unstructured":"Ikeda T, Kamekura S, Mabuchi A, Kou I, Seki S, Takato T, Nakamura K, Kawaguchi H, Ikegawa S, Chung U (2004) The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Arthritis Rheum 50:3561\u20133573","journal-title":"Arthritis Rheum"},{"key":"802_CR42","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1002\/art.21212","volume":"52","author":"Y. Sakaguchi","year":"2005","unstructured":"Sakaguchi Y, Sekiya I, Yagishita K, Muneta T (2005) Comparison of human stem cells derived from various mesenchymal tissues: superiority of synovium as a cell source. Arthritis Rheum 52: 2521\u20132529","journal-title":"Arthritis Rheum"},{"key":"802_CR43","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/art.21651","volume":"54","author":"T. Mochizuki","year":"2006","unstructured":"Mochizuki T, Muneta T, Sakaguchi Y, Nimura A, Yokoyama A, Koga H, Sekiya I (2006) Higher chondrogenic potential of fibrous synovium-and adipose synovium-derived cells compared with subcutaneous fat-derived cells: distinguishing properties of mesenchymal stem cells in humans. Arthritis Rheum 54:843\u2013853","journal-title":"Arthritis Rheum"},{"key":"802_CR44","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1002\/art.20713","volume":"52","author":"M. Nawata","year":"2005","unstructured":"Nawata M, Wakitani S, Nakaya H, Tanigami A, Seki T, Nakamura Y, Saito N, Sano K, Hidaka E, Takaoka K (2005) Use of bone morphogenetic protein-2 and diffusion chambers to engineer cartilage tissue for the repair of defects in articular cartilage. Arthritis Rheum 52:155\u2013163","journal-title":"Arthritis Rheum"},{"key":"802_CR45","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1093\/rheumatology\/keg024","volume":"42","author":"S. Wakitani","year":"2003","unstructured":"Wakitani S, Takaoka K, Hattori T, Miyazawa N, Iwanaga T, Takeda S, Watanabe TK, Tanigami A (2003) Embryonic stem cells injected into the mouse knee joint form teratomas and subsequently destroy the joint. Rheumatology (Oxf) 42:162\u2013165","journal-title":"Rheumatology (Oxf)"},{"key":"802_CR46","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3727\/000000004783983891","volume":"13","author":"S. Wakitani","year":"2004","unstructured":"Wakitani S, Aoki H, Harada Y, Sonobe M, Morita Y, Mu Y, Tomita N, Nakamura Y, Takeda S, Watanabe T, Tanigami A (2004) Embryonic stem cells form articular cartilage, not teratomas, in osteochondral defects of rat joints. Cell Transplant 13:331\u2013336","journal-title":"Cell Transplant"},{"key":"802_CR47","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1093\/rheumatology\/kem220","volume":"46","author":"S. Wakitani","year":"2007","unstructured":"Wakitani S, Nawata M, Kawaguchi A, Okabe T, Takaoka K, Tsuchiya T, Nakaoka R, Masuda H, Miyazaki K (2007) Serum keratan sulfate is a promising marker of early articular cartilage breakdown. Rheumatology (Oxf) 46:1652\u20131656","journal-title":"Rheumatology (Oxf)"},{"key":"802_CR48","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/nm1181","volume":"11","author":"M.J. Martin","year":"2005","unstructured":"Martin MJ, Muotri A, Gage F, Varki A (2005) Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 11:228\u2013232","journal-title":"Nat Med"},{"key":"802_CR49","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1158\/0008-5472.CAN-04-4194","volume":"65","author":"D. Rubio","year":"2005","unstructured":"Rubio D, Garcia-Castro J, Martin MC, de la Fuente R, Cigudosa JC, Lloyd AC, Bernard A (2005) Spontaneous human adult stem cell transformation. Cancer Res 65:3035\u20133039","journal-title":"Cancer Res"}],"container-title":["Journal of Bone and Mineral Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-007-0802-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00774-007-0802-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-007-0802-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,16]],"date-time":"2023-05-16T17:42:58Z","timestamp":1684258978000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00774-007-0802-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,27]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["802"],"URL":"https:\/\/doi.org\/10.1007\/s00774-007-0802-8","relation":{},"ISSN":["0914-8779","1435-5604"],"issn-type":[{"value":"0914-8779","type":"print"},{"value":"1435-5604","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2,27]]}}}