{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:04:23Z","timestamp":1791475463721,"version":"4.3.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2010,7,6]],"date-time":"2010-07-06T00:00:00Z","timestamp":1278374400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Bone Miner Metab"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1007\/s00774-010-0203-2","type":"journal-article","created":{"date-parts":[[2010,7,5]],"date-time":"2010-07-05T04:01:17Z","timestamp":1278302477000},"page":"713-718","source":"Crossref","is-referenced-by-count":12,"title":["Insufficient bilateral femoral subtrochanteric fractures in a patient receiving imatinib mesylate"],"prefix":"10.1007","volume":"28","author":[{"given":"Kyu-Hyun","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Young","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Won","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soon-Hyuck","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Beom","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Woong-Kyo","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk-Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,7,6]]},"reference":[{"key":"203_CR1","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1056\/NEJMra013339","volume":"346","author":"DG Savage","year":"2002","unstructured":"Savage DG, Antman KH (2002) Imatinib mesylate: a new oral targeted therapy. N Engl J Med 346:683\u2013693","journal-title":"N Engl J Med"},{"key":"203_CR2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-230X(04)91001-9","volume":"91","author":"BJ Druker","year":"2004","unstructured":"Druker BJ (2004) Imatinib as a paradigm of targeted therapies. Adv Cancer Res 91:1\u201330","journal-title":"Adv Cancer Res"},{"key":"203_CR3","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1056\/NEJM200104053441401","volume":"344","author":"BJ Druker","year":"2001","unstructured":"Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, Lydon NB, Kantarjian H, Capdeville R, Ohno-Jones S, Sawyers CL (2001) Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 344:1031\u20131037","journal-title":"N Engl J Med"},{"key":"203_CR4","doi-asserted-by":"crossref","first-page":"2006","DOI":"10.1056\/NEJMoa051140","volume":"354","author":"E Berman","year":"2006","unstructured":"Berman E, Nicolaides M, Maki RG, Fleisher M, Chanel S, Scheu K, Wilson BA, Heller G, Sauter NP (2006) Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med 354:2006\u20132013","journal-title":"N Engl J Med"},{"key":"203_CR5","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.1056\/NEJMc062388","volume":"355","author":"A Grey","year":"2006","unstructured":"Grey A, O\u2019Sullivan S, Reid IR, Browett P (2006) Imatinib mesylate, increased bone formation, and secondary hyperparathyroidism. N Engl J Med 355:2494\u20132495","journal-title":"N Engl J Med"},{"key":"203_CR6","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0169-6009(92)90800-S","volume":"18","author":"JE Zerwekh","year":"1992","unstructured":"Zerwekh JE, Antich PP, Sakhaee K, Prior J, Gonzales J, Gottschalk F, Pak CY (1992) Lack of deleterious effect of slow-release sodium fluoride treatment on cortical bone histology and quality in osteoporotic patients. Bone Miner 18:65\u201376","journal-title":"Bone Miner"},{"key":"203_CR7","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1002\/jbmr.5650030203","volume":"3","author":"RR Recker","year":"1988","unstructured":"Recker RR, Kimmel DB, Parfitt AM, Davies KM, Keshawarz N, Hinders S (1988) Static and tetracycline-based bone histomorphometric data from 34 normal postmenopausal females. J Bone Miner Res 3:133\u2013144","journal-title":"J Bone Miner Res"},{"key":"203_CR8","doi-asserted-by":"crossref","first-page":"981","DOI":"10.2106\/00004623-198668070-00004","volume":"68","author":"JD Coe","year":"1986","unstructured":"Coe JD, Murphy WA, Whyte MP (1986) Management of femoral fractures and pseudofractures in adult hypophosphatasia. J Bone Joint Surg Am 68:981\u2013990","journal-title":"J Bone Joint Surg Am"},{"key":"203_CR9","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1359\/jbmr.090408","volume":"24","author":"MP Somford","year":"2009","unstructured":"Somford MP, Draijer FW, Thomassen BJ, Chavassieux PM, Boivin G, Papapoulos SE (2009) Bilateral fractures of the femur diaphysis in a patient with rheumatoid arthritis on long-term treatment with alendronate: clues to the mechanism of increased bone fragility. J Bone Miner Res 24:1736\u20131740","journal-title":"J Bone Miner Res"},{"key":"203_CR10","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1503\/cmaj.071330","volume":"179","author":"LE Targownik","year":"2008","unstructured":"Targownik LE, Lix LM, Metge CJ, Prior HJ, Leung S, Leslie WD (2008) Use of proton pump inhibitors and risk of osteoporosis-related fractures. Can Med Assoc J 179:319\u2013326","journal-title":"Can Med Assoc J"},{"key":"203_CR11","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1359\/JBMR.040134","volume":"19","author":"JA Kanis","year":"2004","unstructured":"Kanis JA, Johansson H, Oden A, Johnell O, de Laet C, Melton IL, Tenenhouse A, Reeve J, Silman AJ, Pols HA, Eisman JA, McCloskey EV, Mellstrom D (2004) A meta-analysis of prior corticosteroid use and fracture risk. J Bone Miner Res 19:893\u2013899","journal-title":"J Bone Miner Res"},{"key":"203_CR12","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1210\/jc.2004-0952","volume":"90","author":"CV Odvina","year":"2005","unstructured":"Odvina CV, Zerwekh JE, Rao DS, Maalouf N, Gottschalk FA, Pak CY (2005) Severely suppressed bone turnover: a potential complication of alendronate therapy. J Clin Endocrinol Metab 90:1294\u20131301","journal-title":"J Clin Endocrinol Metab"},{"key":"203_CR13","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1359\/jbmr.2000.15.4.613","volume":"15","author":"T Mashiba","year":"2000","unstructured":"Mashiba T, Hirano T, Turner CH, Forwood MR, Johnston CC, Burr DB (2000) Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib. J Bone Miner Res 15:613\u2013620","journal-title":"J Bone Miner Res"},{"key":"203_CR14","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1359\/jbmr.070609","volume":"22","author":"RD Chapurlat","year":"2007","unstructured":"Chapurlat RD, Arlot M, Burt-Pichat B, Chavassieux P, Roux JP, Portero-Muzy N, Delmas PD (2007) Microcrack frequency and bone remodeling in postmenopausal osteoporotic women on long-term bisphosphonates: a bone biopsy study. J Bone Miner Res 22:1502\u20131509","journal-title":"J Bone Miner Res"},{"key":"203_CR15","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.leukres.2009.01.040","volume":"33","author":"M Breccia","year":"2009","unstructured":"Breccia M, Alimena G (2009) The metabolic consequences of imatinib mesylate: changes on glucose, lypidic and bone metabolism. Leuk Res 33:871\u2013875","journal-title":"Leuk Res"},{"key":"203_CR16","doi-asserted-by":"crossref","first-page":"4334","DOI":"10.1182\/blood-2005-09-3568","volume":"107","author":"AL Dewar","year":"2006","unstructured":"Dewar AL, Farrugia AN, Condina MR, Bik To L, Hughes TP, Vernon-Roberts B, Zannettino AC (2006) Imatinib as a potential antiresorptive therapy for bone disease. Blood 107:4334\u20134337","journal-title":"Blood"},{"key":"203_CR17","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1126\/science.289.5484.1504","volume":"289","author":"SL Teitelbaum","year":"2000","unstructured":"Teitelbaum SL (2000) Bone resorption by osteoclasts. Science 289:1504\u20131508","journal-title":"Science"},{"key":"203_CR18","doi-asserted-by":"crossref","first-page":"4828","DOI":"10.1073\/pnas.87.12.4828","volume":"87","author":"W Wiktor-Jedrzejczak","year":"1990","unstructured":"Wiktor-Jedrzejczak W, Bartocci A, Ferrante AW Jr, Ahmed-Ansari A, Sell KW, Pollard JW, Stanley ER (1990) Total absence of colony-stimulating factor 1 in the macrophage-deficient osteopetrotic (op\/op) mouse. Proc Natl Acad Sci USA 87:4828\u20134832","journal-title":"Proc Natl Acad Sci USA"},{"key":"203_CR19","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s001980070088","volume":"11","author":"AC Looker","year":"2000","unstructured":"Looker AC, Bauer DC, Chesnut CH 3rd, Gundberg CM, Hochberg MC, Klee G, Kleerekoper M, Watts NB, Bell NH (2000) Clinical use of biochemical markers of bone remodeling: current status and future directions. Osteoporos Int 11:467\u2013480","journal-title":"Osteoporos Int"},{"key":"203_CR20","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1136\/jcp.47.6.529","volume":"47","author":"MT Rehman","year":"1994","unstructured":"Rehman MT, Hoyland JA, Denton J, Freemont AJ (1994) Age related histomorphometric changes in bone in normal British men and women. J Clin Pathol 47:529\u2013534","journal-title":"J Clin Pathol"},{"key":"203_CR21","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1172\/JCI119668","volume":"100","author":"PM Chavassieux","year":"1997","unstructured":"Chavassieux PM, Arlot ME, Reda C, Wei L, Yates AJ, Meunier PJ (1997) Histomorphometric assessment of the long-term effects of alendronate on bone quality and remodeling in patients with osteoporosis. J Clin Invest 100:1475\u20131480","journal-title":"J Clin Invest"},{"key":"203_CR22","first-page":"349","volume":"89","author":"SK Goh","year":"2007","unstructured":"Goh SK, Yang KY, Koh JS, Wong MK, Chua SY, Chua DT, Howe TS (2007) Subtrochanteric insufficiency fractures in patients on alendronate therapy: a caution. J Bone Joint Surg Br 89:349\u2013353","journal-title":"J Bone Joint Surg Br"},{"key":"203_CR23","doi-asserted-by":"crossref","first-page":"2556","DOI":"10.2106\/JBJS.H.01774","volume":"91","author":"CM Capeci","year":"2009","unstructured":"Capeci CM, Tejwani NC (2009) Bilateral low-energy simultaneous or sequential femoral fractures in patients on long-term alendronate therapy. J Bone Joint Surg Am 91:2556\u20132561","journal-title":"J Bone Joint Surg Am"},{"key":"203_CR24","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S8756-3282(99)00257-4","volume":"26","author":"FH Glorieux","year":"2000","unstructured":"Glorieux FH, Travers R, Taylor A, Bowen JR, Rauch F, Norman M, Parfitt AM (2000) Normative data for iliac bone histomorphometry in growing children. Bone (NY) 26:103\u2013109","journal-title":"Bone (NY)"}],"container-title":["Journal of Bone and Mineral Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-010-0203-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00774-010-0203-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-010-0203-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T02:16:40Z","timestamp":1559096200000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00774-010-0203-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,6]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["203"],"URL":"https:\/\/doi.org\/10.1007\/s00774-010-0203-2","relation":{},"ISSN":["0914-8779","1435-5604"],"issn-type":[{"value":"0914-8779","type":"print"},{"value":"1435-5604","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,6]]}}}