{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T07:50:47Z","timestamp":1769845847603,"version":"3.49.0"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2013,11,15]],"date-time":"2013-11-15T00:00:00Z","timestamp":1384473600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Bone Miner Metab"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1007\/s00774-013-0535-9","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T23:01:43Z","timestamp":1384470103000},"page":"593-600","source":"Crossref","is-referenced-by-count":19,"title":["The limited effects of anti-tumor necrosis factor blockade on bone health in patients with rheumatoid arthritis under the use of glucocorticoid"],"prefix":"10.1007","volume":"32","author":[{"given":"Tadashi","family":"Okano","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Koike","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Tada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuko","family":"Sugioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Mamoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeyuki","family":"Wakitani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroaki","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2013,11,15]]},"reference":[{"key":"535_CR1","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1002\/1529-0131(200106)44:6<1254::AID-ART216>3.0.CO;2-G","volume":"44","author":"EJ Kroot","year":"2001","unstructured":"Kroot EJ, Nieuwenhuizen MG, de Waal Malefijt MC, van Riel PL, Pasker-de Jong PC, Laan RF (2001) Change in bone mineral density in patients with rheumatoid arthritis during the first decade of the disease. Arthritis Rheum 44:1254\u20131260","journal-title":"Arthritis Rheum"},{"key":"535_CR2","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0140-6736(94)91049-9","volume":"344","author":"AK Gough","year":"1994","unstructured":"Gough AK, Lilley J, Eyre S, Holder RL, Emery P (1994) Generalised bone loss in patients with early rheumatoid arthritis. Lancet 344:23\u201327","journal-title":"Lancet"},{"key":"535_CR3","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1093\/rheumatology\/35.4.309","volume":"35","author":"AA Deodhar","year":"1996","unstructured":"Deodhar AA, Woolf AD (1996) Bone mass measurement and bone metabolism in rheumatoid arthritis: a review. Br J Rheumatol 35:309\u2013322","journal-title":"Br J Rheumatol"},{"key":"535_CR4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/art.10996","volume":"49","author":"MC Lodder","year":"2003","unstructured":"Lodder MC, Haugeberg G, Lems WF et al (2003) Radiographic damage associated with low bone mineral density and vertebral deformities in rheumatoid arthritis: the Oslo-Truro-Amsterdam (OSTRA) collaborative study. Arthrtis Rheum 49:209\u2013215","journal-title":"Arthrtis Rheum"},{"key":"535_CR5","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1002\/1529-0131(200003)43:3<522::AID-ANR7>3.0.CO;2-Y","volume":"43","author":"G Haugeberg","year":"2000","unstructured":"Haugeberg G, Uhlig T, Falch JA, Halse JI, Kvien TK (2000) Bone mineral density and frequency of osteoporosis in female patients with rheumatoid arthritis: results from 394 patients in the Oslo County Rheumatoid Arthritis register. Arthritis Rheum 43:522\u2013530","journal-title":"Arthritis Rheum"},{"key":"535_CR6","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1136\/ard.54.1.49","volume":"54","author":"C Cooper","year":"1995","unstructured":"Cooper C, Coupland C, Mitchell M (1995) Rheumatoid arthritis, corticosteroid therapy and hip fracture. Ann Rheum Dis 54:49\u201352","journal-title":"Ann Rheum Dis"},{"key":"535_CR7","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1136\/ard.60.5.521","volume":"60","author":"TM Huusko","year":"2001","unstructured":"Huusko TM, Korpela M, Karppi P, Avikainen V, Kautiainen H, Sulkava R (2001) Threefold increased risk of hip fractures with rheumatoid arthritis in Central Finland. Ann Rheum Dis 60:521\u2013522","journal-title":"Ann Rheum Dis"},{"key":"535_CR8","doi-asserted-by":"crossref","first-page":"3104","DOI":"10.1002\/art.22117","volume":"54","author":"TP Staa van","year":"2006","unstructured":"van Staa TP, Geusens P, Bijlsma JW, Leufkens HG, Cooper C (2006) Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum 54:3104\u20133112","journal-title":"Arthritis Rheum"},{"key":"535_CR9","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1136\/bmj.306.6877.558","volume":"306","author":"TD Spector","year":"1993","unstructured":"Spector TD, Hall GM, McCloskey EV, Kanis JA (1993) Risk of vertebral fracture in women with rheumatoid arthritis. BMJ 306:558","journal-title":"BMJ"},{"key":"535_CR10","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1136\/ard.54.10.801","volume":"54","author":"NF Peel","year":"1995","unstructured":"Peel NF, Moore DJ, Barrington NA, Bax DE, Eastell R (1995) Risk of vertebral fracture and relationship to bone mineral density in steroid treated rheumatoid arthritis. Ann Rheum Dis 54:801\u2013806","journal-title":"Ann Rheum Dis"},{"key":"535_CR11","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1002\/1099-1557(200009\/10)9:5<359::AID-PDS507>3.0.CO;2-E","volume":"9","author":"TP Staa Van","year":"2000","unstructured":"Van Staa TP, Abenhaim L, Cooper C, Zhang B, Leufkens HG (2000) The use of a large pharmacoepidemiological database to study exposure to oral corticosteroids and risk of fractures: validation of study population and results. Pharmacoepidemiol Drug Saf 9:359\u2013366","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"535_CR12","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1359\/jbmr.2000.15.6.993","volume":"15","author":"TP Staa Van","year":"2000","unstructured":"Van Staa TP, Leufkens HG, Abenhaim L, Zhang B, Cooper C (2000) Use of oral corticosteroids and risk of fractures. J Bone Miner Res 15:993\u20131000","journal-title":"J Bone Miner Res"},{"key":"535_CR13","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1007\/s001980200084","volume":"13","author":"TP Staa van","year":"2002","unstructured":"van Staa TP, Leufkens HG, Cooper C (2002) The epidemiology of corticosteroid-induced osteoporosis: a meta-analysis. Osteoporos Int 13:777\u2013787","journal-title":"Osteoporos Int"},{"key":"535_CR14","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/art.23721","volume":"59","author":"KG Saag","year":"2008","unstructured":"Saag KG, Teng GG, Patkar NM et al (2008) American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis. Arthritis Rheum 59:762\u2013784","journal-title":"Arthritis Rheum"},{"key":"535_CR15","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1136\/ard.2009.126532","volume":"69","author":"JS Smolen","year":"2010","unstructured":"Smolen JS, Landew\u00e9 R, Breedveld FC et al (2010) EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann Rheum Dis 69:964\u2013975","journal-title":"Ann Rheum Dis"},{"key":"535_CR16","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1136\/ard.2009.123919","volume":"69","author":"JS Smolen","year":"2010","unstructured":"Smolen JS, Aletaha D, Bijlsma JW et al (2010) Treating rheumatoid arthritis to target: recommendations of an international task force. Ann Rheum Dis 69:631\u2013637","journal-title":"Ann Rheum Dis"},{"key":"535_CR17","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/jbmr.5650100212","volume":"10","author":"NE Lane","year":"1995","unstructured":"Lane NE, Pressman AR, Star VL, Cummings SR, Nevitt MC (1995) Rheumatoid arthritis and bone mineral density in elderly women. The Study of Osteoporotic Fractures Research Group. J Bone Miner Res 10:257\u2013263","journal-title":"J Bone Miner Res"},{"key":"535_CR18","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1136\/ard.53.1.18","volume":"53","author":"H Kr\u00f6ger","year":"1994","unstructured":"Kr\u00f6ger H, Honkanen R, Saarikoski S, Alhava E (1994) Decreased axial bone mineral density in perimenopausal women with rheumatoid arthritis\u2014a population-based study. Ann Rheum Dis 53:18\u201323","journal-title":"Ann Rheum Dis"},{"key":"535_CR19","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1136\/ard.2009.123729","volume":"70","author":"UM D\u00f8hn","year":"2011","unstructured":"D\u00f8hn UM, Ejbjerg B, Boonen A et al (2011) No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study. Ann Rheum Dis 70:252\u2013258","journal-title":"Ann Rheum Dis"},{"key":"535_CR20","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1002\/art.20217","volume":"50","author":"EC Keystone","year":"2004","unstructured":"Keystone EC, Avanaugh AF, Sharp JT et al (2004) Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Arthritis Rheum 50:1400\u20131411","journal-title":"Arthritis Rheum"},{"key":"535_CR21","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/art.20982","volume":"52","author":"JS Smolen","year":"2005","unstructured":"Smolen JS, Han C, Bala M et al (2005) Evidence of radiographic benefit of treatment with infliximab plus methotrexate in rheumatoid arthritis patients who had no clinical improvement: a detailed subanalysis of data from the anti-tumor necrosis factor trial in rheumatoid arthritis with concomitant therapy study. Arthritis Rheum 52:1020\u20131030","journal-title":"Arthritis Rheum"},{"key":"535_CR22","doi-asserted-by":"crossref","first-page":"1699","DOI":"10.1172\/JCI119333","volume":"99","author":"P Ammann","year":"1997","unstructured":"Ammann P, Rizzoli R, Bonjour JP et al (1997) Transgenic mice expressing soluble tumor necrosis factor-receptor are protected against bone loss caused by estrogen deficiency. J Clin Invest 99:1699\u20131703","journal-title":"J Clin Invest"},{"key":"535_CR23","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1002\/art.1780310302","volume":"31","author":"FC Arnett","year":"1988","unstructured":"Arnett FC, Edworthy SM, Bloch DA et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315\u2013324","journal-title":"Arthritis Rheum"},{"key":"535_CR24","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/art.1780380107","volume":"38","author":"ML Prevoo","year":"1995","unstructured":"Prevoo ML, van\u2019t Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL (1995) Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 38:44\u201348","journal-title":"Arthritis Rheum"},{"key":"535_CR25","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1002\/art.1780230202","volume":"23","author":"JF Fries","year":"1980","unstructured":"Fries JF, Spitz P, Kraines RG, Holman HR (1980) Measurement of patient outcome in arthritis. Arthritis Rheum 23:137\u2013145","journal-title":"Arthritis Rheum"},{"key":"535_CR26","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1136\/ard.52.1.21","volume":"52","author":"RF Laan","year":"1993","unstructured":"Laan RF, Buijs WC, Verbeek AL et al (1993) Bone mineral density in patients with recent onset rheumatoid arthritis: influence of disease activity and functional capacity. Ann Rheum Dis 52:21\u201326","journal-title":"Ann Rheum Dis"},{"key":"535_CR27","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1002\/art.1780361105","volume":"36","author":"GM Hall","year":"1993","unstructured":"Hall GM, Spector TD, Griffin AJ, Jawad AS, Hall ML, Doyle DV (1993) The effect of rheumatoid arthritis and steroid therapy on bone density in postmenopausal women. Arthritis Rheum 36:1510\u20131516","journal-title":"Arthritis Rheum"},{"key":"535_CR28","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1002\/art.10408","volume":"46","author":"G Haugeberg","year":"2002","unstructured":"Haugeberg G, \u00d8rstavik RE, Uhlig T, Falch JA, Halse JI, Kvien TK (2002) Bone loss in patients with rheumatoid arthritis: results from a population-based cohort of 366 patients followed up for two years. Arthritis Rheum 46:1720\u20131728","journal-title":"Arthritis Rheum"},{"key":"535_CR29","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1093\/rheumatology\/33.6.541","volume":"33","author":"BD Shenstone","year":"1994","unstructured":"Shenstone BD, Mahmoud A, Woodward R et al (1994) Longitudinal bone mineral density changes in early rheumatoid arthritis. Br J Rheumatol 33:541\u2013545","journal-title":"Br J Rheumatol"},{"key":"535_CR30","first-page":"683","volume":"18","author":"B Cortet","year":"2000","unstructured":"Cortet B, Guyot MH, Solau E et al (2000) Factors influencing bone loss in rheumatoid arthritis: a longitudinal study. Clin Exp Rheumatol 18:683\u2013690","journal-title":"Clin Exp Rheumatol"},{"key":"535_CR31","first-page":"2590","volume":"30","author":"Forslind K, Keller C, Svensson B, Hafstr\u00f6m I, Group BS","year":"2003","unstructured":"Forslind K, Keller C, Svensson B, Hafstr\u00f6m I, Group BS (2003) Reduced bone mineral density in early rheumatoid arthritis is associated with radiological joint damage at baseline and after 2\u00a0years in women. J Rheumatol 30:2590\u20132596","journal-title":"J Rheumatol"},{"key":"535_CR32","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1136\/ard.2003.013888","volume":"63","author":"T Jensen","year":"2004","unstructured":"Jensen T, Klarlund M, Hansen M et al (2004) Bone loss in unclassified polyarthritis and early rheumatoid arthritis is better detected by digital X ray radiogrammetry than dual X ray absorptiometry: relationship with disease activity and radiographic outcome. Ann Rheum Dis 63:15\u201322","journal-title":"Ann Rheum Dis"},{"key":"535_CR33","doi-asserted-by":"crossref","first-page":"R61","DOI":"10.1186\/ar2219","volume":"9","author":"H Marotte","year":"2007","unstructured":"Marotte H, Pallot-Prades B, Grange L, Gaudin P, Alexandre C, Miossec P (2007) A 1-year case-control study in patients with rheumatoid arthritis indicates prevention of loss of bone mineral density in both responders and nonresponders to infliximab. Arthritis Res Ther 9:R61","journal-title":"Arthritis Res Ther"},{"key":"535_CR34","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1093\/rheumatology\/kei082","volume":"44","author":"U Lange","year":"2005","unstructured":"Lange U, Teichmann J, M\u00fcller-Ladner U, Strunk J (2005) Increase in bone mineral density of patients with rheumatoid arthritis treated with anti-TNF-alpha antibody: a prospective open-label pilot study. Rheumatology (Oxf) 44:1546\u20131548","journal-title":"Rheumatology (Oxf)"},{"key":"535_CR35","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1136\/ard.2007.076604","volume":"67","author":"F Chopin","year":"2008","unstructured":"Chopin F, Garnero P, le Henanff A et al (2008) Long-term effects of infliximab on bone and cartilage turnover markers in patients with rheumatoid arthritis. Ann Rheum Dis 67:353\u2013357","journal-title":"Ann Rheum Dis"}],"container-title":["Journal of Bone and Mineral Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-013-0535-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00774-013-0535-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-013-0535-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,29]],"date-time":"2019-05-29T06:16:51Z","timestamp":1559110611000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00774-013-0535-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11,15]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["535"],"URL":"https:\/\/doi.org\/10.1007\/s00774-013-0535-9","relation":{},"ISSN":["0914-8779","1435-5604"],"issn-type":[{"value":"0914-8779","type":"print"},{"value":"1435-5604","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,11,15]]}}}