{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,26]],"date-time":"2025-08-26T06:53:39Z","timestamp":1756191219521},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T00:00:00Z","timestamp":1498694400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Bone Miner Metab"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1007\/s00774-017-0851-6","type":"journal-article","created":{"date-parts":[[2017,6,29]],"date-time":"2017-06-29T09:50:39Z","timestamp":1498729839000},"page":"447-453","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Association between leg bowing and serum alkaline phosphatase level regardless of the presence of a radiographic growth plate abnormality in pediatric patients with genu varum"],"prefix":"10.1007","volume":"36","author":[{"given":"Yuko","family":"Sakamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muneaki","family":"Ishijima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mayuko","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lizu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuyoshi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Gon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Kamata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akifumi","family":"Tokita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haruka","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshiaki","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Kaneko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiko","family":"Nozawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,6,29]]},"reference":[{"key":"851_CR1","first-page":"973","volume-title":"Chapter 22 Disorders of the leg","author":"JA Herring","year":"2008","unstructured":"Herring JA (2008) Tachdjian\u2019s Pediatric Orthopaedics From the Texas Scottish Rite Hospital for Children, 4th edition. Chapter 22 Disorders of the leg. Elsevier, Amsterdam, pp 973\u2013974"},{"issue":"8","key":"851_CR2","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.2106\/00004623-198264080-00006","volume":"64","author":"AM Levine","year":"1982","unstructured":"Levine AM, Drennan JC, Contcut N (1982) Physiological Bowing and Tibia Vara. J Bone Jt Surg Am 64(8):1158\u20131163","journal-title":"J Bone Jt Surg Am"},{"key":"851_CR3","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1302\/0301-620X.84B2.11821","volume":"84","author":"Y Shinohara","year":"2002","unstructured":"Shinohara Y, Kamegaya M, Kuniyoshi K, Moriya H (2002) Natural history of infantile tibia vara. J Bone Jt Surg Br 84:263\u2013268","journal-title":"J Bone Jt Surg Br"},{"key":"851_CR4","unstructured":"Tanaka H, Ozono K, Kitanaka S, Tajima T, Hasegawa K, Hujiwara I, Michigami T, Minagawa M, Miyako K (2013) Clinical guide to the diagnosis of rickets and hypocalcemia due to vitamin D deficiency. Jpn Soc Pediatric Endocrinol"},{"key":"851_CR5","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1097\/BPO.0b013e3181f5a0b3","volume":"30","author":"CO Montgomery","year":"2010","unstructured":"Montgomery CO, Young KL, Austen M, Jo CH, Blasier RD, Ilyas M (2010) Increased risk of Blount disease in obese children and adolescents with vitamin D deficiency. J Pediatr Orthop 30:879\u2013882","journal-title":"J Pediatr Orthop"},{"key":"851_CR6","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.2106\/JBJS.H.01348","volume":"91","author":"S Sabharwal","year":"2009","unstructured":"Sabharwal S (2009) Blount disease. J Bone Jt Surg Am 91:1758\u20131776","journal-title":"J Bone Jt Surg Am"},{"key":"851_CR7","first-page":"1203","volume":"96","author":"OG Giwa","year":"2004","unstructured":"Giwa OG, Anetor JI, Alonge TO, Agbedana EO (2004) Biochemical observations in Blount\u2019s disease (infantile tibia vara). J Natl Med Assoc 96:1203\u20131207","journal-title":"J Natl Med Assoc"},{"key":"851_CR8","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1097\/00003086-198107000-00011","volume":"158","author":"A Langenski\u00f6ld","year":"1981","unstructured":"Langenski\u00f6ld A (1981) Tibia vara: osteochondrosis deformans tibiae. Blount\u2019s disease. Clin Orthop Relat Res 158:77\u201382","journal-title":"Clin Orthop Relat Res"},{"key":"851_CR9","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1097\/01241398-199607000-00008","volume":"16","author":"JR Davids","year":"1996","unstructured":"Davids JR, Huskamp M, Bagley AM (1996) A dynamic biomechanical analysis of the etiology of adolescent tibia vara. J Pediatr Orthop 16:461\u2013468","journal-title":"J Pediatr Orthop"},{"key":"851_CR10","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2106\/00004623-197557020-00021","volume":"57","author":"P Salenius","year":"1975","unstructured":"Salenius P, Vankka E (1975) The development of the tibiofemoral angle in children. J Bone Jt Surg Am 57:259\u2013261","journal-title":"J Bone Jt Surg Am"},{"key":"851_CR11","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/s00223-005-0233-2","volume":"76","author":"A Voloc","year":"2005","unstructured":"Voloc A, Esterle L, Nguyen TM, Walrant-Debray O, Colofitchi A, Jehan F, Garabedian M (2005) High prevalence of genu varum\/valgum in European children with low vitamin D status and insufficient dairy products\/calcium intakes. Calcif Tissue Int 76:412\u2013418","journal-title":"Calcif Tissue Int"},{"key":"851_CR12","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/jbmr.5650090407","volume":"9","author":"CM Schnitzler","year":"1994","unstructured":"Schnitzler CM, Pettifor JM, Patel D, Mesquita JM, Moodley GP, Zachen D (1994) Metabolic bone disease in black teenagers with genu valgum or varum without radiologic rickets: a bone histomorphometric study. J Bone Miner Res 9:479\u2013486","journal-title":"J Bone Miner Res"},{"key":"851_CR13","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/00003086-198910000-00038","volume":"247","author":"NC Blumenthal","year":"1989","unstructured":"Blumenthal NC (1989) Mechanisms of inhibition of calcification. Clin Orthop Relat Res 247:279\u2013289","journal-title":"Clin Orthop Relat Res"},{"key":"851_CR14","first-page":"1353","volume":"23","author":"N Amizuka","year":"2008","unstructured":"Amizuka N, Li M, Kobayashi M, Hara K, Akahane S, Takeuchi K (2008) Vitamin K2, a gamma-carboxylating factor of gla-proteins, normalizes the bone crystal nucleation impaired by Mg-insufficiency. Histol Histopathol 23:1353\u20131366","journal-title":"Histol Histopathol"},{"key":"851_CR15","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1016\/j.bone.2004.05.012","volume":"35","author":"M Kobayashi","year":"2004","unstructured":"Kobayashi M, Hara K, Akiyama Y (2004) Effects of vitamin K2 (menatetrenone) and alendronate on bone mineral density and bone strength in rats fed a low-magnesium diet. Bone 35:1136\u20131143","journal-title":"Bone"},{"key":"851_CR16","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1017\/S0007114515004286","volume":"28","author":"LA Atkins","year":"2016","unstructured":"Atkins LA, McNaughton SA, Campbell KJ, Szymlek-Gay EA (2016) Iron intakes of Australian infants and toddlers: findings from the Melbourne Infant Feeding, Activity and Nutrition Trial (InFANT) Program. Br J Nutr 28:285\u2013293","journal-title":"Br J Nutr"},{"key":"851_CR17","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1373\/clinchem.2015.239731","volume":"61","author":"J Zierk","year":"2015","unstructured":"Zierk J, Arzideh F, Rechenauer T, Haeckel R, Rascher W, Metzler M, Rauh M (2015) Age- and sex-specific dynamics in 22 hematologic and biochemical analytes from birth to adolescence. Clin Chem 61:964\u2013973","journal-title":"Clin Chem"},{"key":"851_CR18","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1177\/0009922810376993","volume":"49","author":"JA Taylor","year":"2010","unstructured":"Taylor JA, Richter M, Done S, Feldman KW (2010) The utility of alkaline phosphatase measurement as a screening test for rickets in breast-fed infants and toddlers: a study from the Puget sound pediatric research network. Clin Pediatr 49:1103\u20131110","journal-title":"Clin Pediatr"},{"key":"851_CR19","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1542\/pir.21-9-296","volume":"21","author":"TA Joiner","year":"2000","unstructured":"Joiner TA, Foster C, Shope T (2000) The many faces of vitamin D deficiency rickets. Pediatr Rev 21:296\u2013302","journal-title":"Pediatr Rev"},{"key":"851_CR20","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1542\/peds.2007-1894","volume":"122","author":"M Misra","year":"2008","unstructured":"Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M (2008) Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 122:398\u2013417","journal-title":"Pediatrics"},{"key":"851_CR21","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2106\/00004623-197557020-00021","volume":"57","author":"P Salenius","year":"1975","unstructured":"Salenius P, Vankka E (1975) The development of the tibiofemoral angle in children. J Bone Jt Surg Am 57:259\u2013261","journal-title":"J Bone Jt Surg Am"},{"key":"851_CR22","first-page":"259","volume":"13","author":"CH Heath","year":"1993","unstructured":"Heath CH, Staheli LT (1993) Normal limits of knee angle in white children genu varum and genu valgum. J Pediatr Orthop 13:259\u2013262","journal-title":"J Pediatr Orthop"},{"key":"851_CR23","doi-asserted-by":"crossref","first-page":"130","DOI":"10.2106\/00004623-199301000-00017","volume":"75","author":"WB Greene","year":"1993","unstructured":"Greene WB (1993) Infantile tibia vara. J Bone Jt Surg Am 75:130\u2013143","journal-title":"J Bone Jt Surg Am"}],"container-title":["Journal of Bone and Mineral Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00774-017-0851-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-017-0851-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-017-0851-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,30]],"date-time":"2022-07-30T04:13:47Z","timestamp":1659154427000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00774-017-0851-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,29]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["851"],"URL":"https:\/\/doi.org\/10.1007\/s00774-017-0851-6","relation":{},"ISSN":["0914-8779","1435-5604"],"issn-type":[{"value":"0914-8779","type":"print"},{"value":"1435-5604","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,29]]}}}