{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T11:04:30Z","timestamp":1778843070631,"version":"3.51.4"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T00:00:00Z","timestamp":1508198400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"JSPS KAKENHI","award":["25870523"],"award-info":[{"award-number":["25870523"]}]},{"name":"JSPS KAKENHI","award":["15K11258"],"award-info":[{"award-number":["15K11258"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Bone Miner Metab"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1007\/s00774-017-0872-1","type":"journal-article","created":{"date-parts":[[2017,10,17]],"date-time":"2017-10-17T06:27:11Z","timestamp":1508221631000},"page":"547-559","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Effect of anti-angiogenesis induced by chemotherapeutic monotherapy, chemotherapeutic\/bisphosphonate combination therapy and anti-VEGFA mAb therapy on tooth extraction socket healing in mice"],"prefix":"10.1007","volume":"36","author":[{"given":"Yuri","family":"Akita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9891-9987","authenticated-orcid":false,"given":"Shinichiro","family":"Kuroshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazunori","family":"Nakajima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Hayano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riho","family":"Kanai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muneteru","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Sawase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,10,17]]},"reference":[{"key":"872_CR1","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/S0278-2391(03)00720-1","volume":"61","author":"RE Marx","year":"2003","unstructured":"Marx RE (2003) Pamidronate (Aredia) and zoledronate (Zometa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillofac Surg 61:1115\u20131117","journal-title":"J Oral Maxillofac Surg"},{"key":"872_CR2","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/jbmr.2405","volume":"30","author":"AA Khan","year":"2015","unstructured":"Khan AA, Morrison A, Hanley DA, Felsenberg D, McCauley LK et al (2015) Diagnosis and management of osteonecrosis of the jaw: a systematic review and international consensus. J Bone Miner Res 30:3\u201323. doi:\n                        10.1002\/jbmr.2405","journal-title":"J Bone Miner Res"},{"key":"872_CR3","doi-asserted-by":"publisher","first-page":"1938","DOI":"10.1016\/j.joms.2014.04.031","volume":"72","author":"SL Ruggiero","year":"2014","unstructured":"Ruggiero SL, Dodson TB, Fantasia J, Goodday R, Aghaloo T, Mehrotra B, O\u2019Ryan F, Surgeons AAOSM (2014) American association of oral and maxillofacial surgeons position paper on medication-related osteonecrosis of the jaw-2014 update. J Oral Maxillofac Surg 72:1938\u20131956. doi:\n                        10.1016\/j.joms.2014.04.031","journal-title":"J Oral Maxillofac Surg"},{"key":"872_CR4","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1634\/theoncologist.2010-0183","volume":"16","author":"RA Miksad","year":"2011","unstructured":"Miksad RA, Lai KC, Dodson TB, Woo SB, Treister NS, Akinyemi O, Bihrle M, Maytal G, August M, Gazelle GS, Swan JS (2011) Quality of life implications of bisphosphonate-associated osteonecrosis of the jaw. Oncologist 16:121\u2013132. doi:\n                        10.1634\/theoncologist.2010-0183","journal-title":"Oncologist"},{"key":"872_CR5","doi-asserted-by":"publisher","first-page":"43603","DOI":"10.1074\/jbc.M308114200","volume":"278","author":"M Bezzi","year":"2003","unstructured":"Bezzi M, Hasmim M, Bieler G, Dormond O, R\u00fcegg C (2003) Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B\/Akt. J Biol Chem 278:43603\u201343614. doi:\n                        10.1074\/jbc.M308114200","journal-title":"J Biol Chem"},{"key":"872_CR6","doi-asserted-by":"publisher","first-page":"20580","DOI":"10.1038\/srep20580","volume":"6","author":"D Sharma","year":"2016","unstructured":"Sharma D, Hamlet SM, Petcu EB, Ivanovski S (2016) The effect of bisphosphonates on the endothelial differentiation of mesenchymal stem cells. Sci Rep 6:20580. doi:\n                        10.1038\/srep20580","journal-title":"Sci Rep"},{"key":"872_CR7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1210\/en.2011-1439","volume":"153","author":"S Kuroshima","year":"2012","unstructured":"Kuroshima S, Go VA, Yamashita J (2012) Increased numbers of nonattached osteoclasts after long-term zoledronic acid therapy in mice. Endocrinology 153:17\u201328. doi:\n                        10.1210\/en.2011-1439","journal-title":"Endocrinology"},{"key":"872_CR8","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.bone.2013.05.013","volume":"56","author":"S Kuroshima","year":"2013","unstructured":"Kuroshima S, Yamashita J (2013) Chemotherapeutic and antiresorptive combination therapy suppressed lymphangiogenesis and induced osteonecrosis of the jaw-like lesions in mice. Bone 56:101\u2013109. doi:\n                        10.1016\/j.bone.2013.05.013","journal-title":"Bone"},{"key":"872_CR9","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1902\/jop.2013.130094","volume":"85","author":"S Kuroshima","year":"2014","unstructured":"Kuroshima S, Mecano RB, Tanoue R, Koi K, Yamashita J (2014) Distinctive tooth-extraction socket healing: bisphosphonate versus parathyroid hormone therapy. J Periodontol 85:24\u201333. doi:\n                        10.1902\/jop.2013.130094","journal-title":"J Periodontol"},{"key":"872_CR10","doi-asserted-by":"publisher","first-page":"1251","DOI":"10.1177\/0022034515592867","volume":"94","author":"R Tanoue","year":"2015","unstructured":"Tanoue R, Koi K, Yamashita J (2015) Effect of alendronate on bone formation during tooth extraction wound healing. J Dent Res 94:1251\u20131258. doi:\n                        10.1177\/0022034515592867","journal-title":"J Dent Res"},{"key":"872_CR11","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/j.ijom.2015.01.026","volume":"44","author":"R Fliefel","year":"2015","unstructured":"Fliefel R, Tr\u00f6ltzsch M, K\u00fchnisch J, Ehrenfeld M, Otto S (2015) Treatment strategies and outcomes of bisphosphonate-related osteonecrosis of the jaw (BRONJ) with characterization of patients: a systematic review. Int J Oral Maxillofac Surg 44:568\u2013585. doi:\n                        10.1016\/j.ijom.2015.01.026","journal-title":"Int J Oral Maxillofac Surg"},{"key":"872_CR12","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1038\/nrc3185","volume":"12","author":"D Fu","year":"2012","unstructured":"Fu D, Calvo JA, Samson LD (2012) Balancing repair and tolerance of DNA damage caused by alkylating agents. Nat Rev Cancer 12:104\u2013120. doi:\n                        10.1038\/nrc3185","journal-title":"Nat Rev Cancer"},{"key":"872_CR13","doi-asserted-by":"publisher","first-page":"2239","DOI":"10.1158\/0008-5472.CAN-11-3016","volume":"72","author":"R Lu","year":"2012","unstructured":"Lu R, Kujawski M, Pan H, Shively JE (2012) Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1. Cancer Res 72:2239\u20132250. doi:\n                        10.1158\/0008-5472.CAN-11-3016","journal-title":"Cancer Res"},{"key":"872_CR14","doi-asserted-by":"publisher","first-page":"4130","DOI":"10.1016\/j.jbiomech.2015.10.025","volume":"48","author":"M Sasaki","year":"2015","unstructured":"Sasaki M, Kuroshima S, Aoki Y, Inaba N, Sawase T (2015) Ultrastructural alterations of osteocyte morphology via loaded implants in rabbit tibiae. J Biomech 48:4130\u20134141. doi:\n                        10.1016\/j.jbiomech.2015.10.025","journal-title":"J Biomech"},{"key":"872_CR15","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1177\/0022034513487558","volume":"92","author":"S Kuroshima","year":"2013","unstructured":"Kuroshima S, Kovacic BL, Kozloff KM, McCauley LK, Yamashita J (2013) Intra-oral PTH administration promotes tooth extraction socket healing. J Dent Res 92:553\u2013559. doi:\n                        10.1177\/0022034513487558","journal-title":"J Dent Res"},{"key":"872_CR16","doi-asserted-by":"publisher","first-page":"1468","DOI":"10.1002\/jbmr.141","volume":"25","author":"ML Bouxsein","year":"2010","unstructured":"Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, M\u00fcller R (2010) Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res 25:1468\u20131486. doi:\n                        10.1002\/jbmr.141","journal-title":"J Bone Miner Res"},{"key":"872_CR17","doi-asserted-by":"publisher","first-page":"1405","DOI":"10.1158\/1078-0432.CCR-10-1614","volume":"17","author":"J Yamashita","year":"2011","unstructured":"Yamashita J, Koi K, Yang DY, McCauley LK (2011) Effect of zoledronate on oral wound healing in rats. Clin Cancer Res 17:1405\u20131414. doi:\n                        10.1158\/1078-0432.CCR-10-1614","journal-title":"Clin Cancer Res"},{"key":"872_CR18","doi-asserted-by":"publisher","first-page":"648","DOI":"10.1016\/j.chembiol.2013.04.007","volume":"20","author":"K Cheung-Ong","year":"2013","unstructured":"Cheung-Ong K, Giaever G, Nislow C (2013) DNA-damaging agents in cancer chemotherapy: serendipity and chemical biology. Chem Biol 20:648\u2013659. doi:\n                        10.1016\/j.chembiol.2013.04.007","journal-title":"Chem Biol"},{"key":"872_CR19","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1159\/000146262","volume":"127","author":"TM Wang","year":"1986","unstructured":"Wang TM, Shih C (1986) Study of histomorphometric changes of the mandibular condyles in neonatal and juvenile rats after administration of cyclophosphamide. Acta Anat (Basel) 127:93\u201399","journal-title":"Acta Anat (Basel)"},{"key":"872_CR20","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1200\/JCO.1992.10.8.1266","volume":"10","author":"S Vadhan-Raj","year":"1992","unstructured":"Vadhan-Raj S, Broxmeyer HE, Hittelman WN, Papadopoulos NE, Chawla SP, Fenoglio C, Cooper S, Buescher ES, Frenck RW, Holian A (1992) Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: protection at the progenitor cell level. J Clin Oncol 10:1266\u20131277","journal-title":"J Clin Oncol"},{"key":"872_CR21","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0901-5027(06)80137-2","volume":"24","author":"K Okabe","year":"1995","unstructured":"Okabe K, Nakagawa K, Yamamoto E (1995) Factors affecting the occurrence of bacteremia associated with tooth extraction. Int J Oral Maxillofac Surg 24:239\u2013242","journal-title":"Int J Oral Maxillofac Surg"},{"key":"872_CR22","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1111\/j.1601-0825.2006.01247.x","volume":"13","author":"I Tom\u00e1s","year":"2007","unstructured":"Tom\u00e1s I, Alvarez M, Limeres J, Potel C, Medina J, Diz P (2007) Prevalence, duration and aetiology of bacteraemia following dental extractions. Oral Dis 13:56\u201362. doi:\n                        10.1111\/j.1601-0825.2006.01247.x","journal-title":"Oral Dis"},{"key":"872_CR23","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1056\/NEJM199909023411006","volume":"341","author":"AJ Singer","year":"1999","unstructured":"Singer AJ, Clark RA (1999) Cutaneous wound healing. N Engl J Med 341:738\u2013746. doi:\n                        10.1056\/NEJM199909023411006","journal-title":"N Engl J Med"},{"key":"872_CR24","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1038\/mi.2012.24","volume":"5","author":"BM Fournier","year":"2012","unstructured":"Fournier BM, Parkos CA (2012) The role of neutrophils during intestinal inflammation. Mucosal Immunol 5:354\u2013366. doi:\n                        10.1038\/mi.2012.24","journal-title":"Mucosal Immunol"},{"key":"872_CR25","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1038\/mi.2015.63","volume":"8","author":"G Leoni","year":"2015","unstructured":"Leoni G, Neumann PA, Sumagin R, Denning TL, Nusrat A (2015) Wound repair: role of immune\u2013epithelial interactions. Mucosal Immunol 8:959\u2013968. doi:\n                        10.1038\/mi.2015.63","journal-title":"Mucosal Immunol"},{"key":"872_CR26","first-page":"1878","volume":"60","author":"T Browder","year":"2000","unstructured":"Browder T, Butterfield CE, Kr\u00e4ling BM, Shi B, Marshall B, O\u2019Reilly MS, Folkman J (2000) Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 60:1878\u20131886","journal-title":"Cancer Res"},{"key":"872_CR27","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1172\/JCI9872","volume":"105","author":"D Hanahan","year":"2000","unstructured":"Hanahan D, Bergers G, Bergsland E (2000) Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J Clin Invest 105:1045\u20131047. doi:\n                        10.1172\/JCI9872","journal-title":"J Clin Invest"},{"key":"872_CR28","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1038\/nrc1369","volume":"4","author":"RS Kerbel","year":"2004","unstructured":"Kerbel RS, Kamen BA (2004) The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 4:423\u2013436. doi:\n                        10.1038\/nrc1369","journal-title":"Nat Rev Cancer"},{"key":"872_CR29","doi-asserted-by":"publisher","first-page":"3517","DOI":"10.4049\/jimmunol.1003267","volume":"186","author":"JL Guerriero","year":"2011","unstructured":"Guerriero JL, Ditsworth D, Catanzaro JM, Sabino G, Furie MB, Kew RR, Crawford HC, Zong WX (2011) DNA alkylating therapy induces tumor regression through an HMGB1-mediated activation of innate immunity. J Immunol 186:3517\u20133526. doi:\n                        10.4049\/jimmunol.1003267","journal-title":"J Immunol"},{"key":"872_CR30","doi-asserted-by":"publisher","first-page":"e19389","DOI":"10.1371\/journal.pone.0019389","volume":"6","author":"TT Ji Hung","year":"2011","unstructured":"Ji Hung TT, Chan J, Russell PJ, Power CA (2011) Zoledronic acid preserves bone structure and increases survival but does not limit tumour incidence in a prostate cancer bone metastasis model. PLoS ONE 6:e19389. doi:\n                        10.1371\/journal.pone.0019389","journal-title":"PLoS ONE"},{"key":"872_CR31","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1016\/j.archoralbio.2010.11.003","volume":"56","author":"MJ Ravosa","year":"2011","unstructured":"Ravosa MJ, Ning J, Liu Y, Stack MS (2011) Bisphosphonate effects on the behaviour of oral epithelial cells and oral fibroblasts. Arch Oral Biol 56:491\u2013498. doi:\n                        10.1016\/j.archoralbio.2010.11.003","journal-title":"Arch Oral Biol"},{"key":"872_CR32","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1007\/s00784-009-0266-4","volume":"14","author":"C Walter","year":"2010","unstructured":"Walter C, Klein MO, Pabst A, Al-Nawas B, Duschner H, Ziebart T (2010) Influence of bisphosphonates on endothelial cells, fibroblasts, and osteogenic cells. Clin Oral Investig 14:35\u201341. doi:\n                        10.1007\/s00784-009-0266-4","journal-title":"Clin Oral Investig"},{"key":"872_CR33","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s00774-009-0128-9","volume":"28","author":"Y Kobayashi","year":"2010","unstructured":"Kobayashi Y, Hiraga T, Ueda A, Wang L, Matsumoto-Nakano M, Hata K, Yatani H, Yoneda T (2010) Zoledronic acid delays wound healing of the tooth extraction socket, inhibits oral epithelial cell migration, and promotes proliferation and adhesion to hydroxyapatite of oral bacteria, without causing osteonecrosis of the jaw, in mice. J Bone Miner Metab 28:165\u2013175. doi:\n                        10.1007\/s00774-009-0128-9","journal-title":"J Bone Miner Metab"},{"key":"872_CR34","first-page":"2893","volume":"9","author":"D Santini","year":"2003","unstructured":"Santini D, Vincenzi B, Dicuonzo G, Avvisati G, Massacesi C, Battistoni F, Gavasci M, Rocci L, Tirindelli MC, Altomare V, Tocchini M, Bonsignori M, Tonini G (2003) Zoledronic acid induces significant and long-lasting modifications of circulating angiogenic factors in cancer patients. Clin Cancer Res 9:2893\u20132897","journal-title":"Clin Cancer Res"},{"key":"872_CR35","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s10549-010-0866-3","volume":"122","author":"V Guarneri","year":"2010","unstructured":"Guarneri V, Miles D, Robert N, Di\u00e9ras V, Glaspy J, Smith I, Thomssen C, Biganzoli L, Taran T, Conte P (2010) Bevacizumab and osteonecrosis of the jaw: incidence and association with bisphosphonate therapy in three large prospective trials in advanced breast cancer. Breast Cancer Res Treat 122:181\u2013188. doi:\n                        10.1007\/s10549-010-0866-3","journal-title":"Breast Cancer Res Treat"},{"key":"872_CR36","doi-asserted-by":"crossref","first-page":"506","DOI":"10.14219\/jada.archive.2011.0220","volume":"142","author":"F Francini","year":"2011","unstructured":"Francini F, Pascucci A, Francini E, Miano ST, Bargagli G, Ruggiero G, Petrioli R (2011) Osteonecrosis of the jaw in patients with cancer who received zoledronic acid and bevacizumab. J Am Dent Assoc 142:506\u2013513","journal-title":"J Am Dent Assoc"},{"key":"872_CR37","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.bone.2009.07.011","volume":"45","author":"P Lesclous","year":"2009","unstructured":"Lesclous P, Abi Najm S, Carrel JP, Baroukh B, Lombardi T, Willi JP, Rizzoli R, Saffar JL, Samson J (2009) Bisphosphonate-associated osteonecrosis of the jaw: a key role of inflammation? Bone 45:843\u2013852. doi:\n                        10.1016\/j.bone.2009.07.011","journal-title":"Bone"},{"key":"872_CR38","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1111\/j.1600-0714.2006.00391.x","volume":"35","author":"T Hansen","year":"2006","unstructured":"Hansen T, Kunkel M, Weber A, James Kirkpatrick C (2006) Osteonecrosis of the jaws in patients treated with bisphosphonates\u2014histomorphologic analysis in comparison with infected osteoradionecrosis. J Oral Pathol Med 35:155\u2013160. doi:\n                        10.1111\/j.1600-0714.2006.00391.x","journal-title":"J Oral Pathol Med"},{"key":"872_CR39","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1016\/j.joms.2011.02.104","volume":"70","author":"RN Hopp","year":"2012","unstructured":"Hopp RN, Pucci J, Santos-Silva AR, Jorge J (2012) Osteonecrosis after administration of intravitreous bevacizumab. J Oral Maxillofac Surg 70:632\u2013635. doi:\n                        10.1016\/j.joms.2011.02.104","journal-title":"J Oral Maxillofac Surg"},{"key":"872_CR40","doi-asserted-by":"publisher","first-page":"e32","DOI":"10.1016\/j.oooo.2013.02.001","volume":"115","author":"AR Santos-Silva","year":"2013","unstructured":"Santos-Silva AR, Beliz\u00e1rio Rosa GA, Castro J\u00fanior G, Dias RB, Prado Ribeiro AC, Brand\u00e3o TB (2013) Osteonecrosis of the mandible associated with bevacizumab therapy. Oral Surg Oral Med Oral Pathol Oral Radiol 115:e32\u2013e36. doi:\n                        10.1016\/j.oooo.2013.02.001","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"}],"container-title":["Journal of Bone and Mineral Metabolism"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00774-017-0872-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-017-0872-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00774-017-0872-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,8,27]],"date-time":"2018-08-27T21:03:23Z","timestamp":1535403803000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00774-017-0872-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,17]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["872"],"URL":"https:\/\/doi.org\/10.1007\/s00774-017-0872-1","relation":{},"ISSN":["0914-8779","1435-5604"],"issn-type":[{"value":"0914-8779","type":"print"},{"value":"1435-5604","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,17]]}}}