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Ikeda has received payments for lectures, including speakers\u2019 bureau fees, from Chugai Pharmaceutical Co., Ltd, Daiichi-Sankyo Co., Ltd., Pfizer Japan Inc., Takeda Pharmaceutical Co., and Teijin Pharma Ltd. A Sakai has received lecture fee from Asahi Kasei Pharma Corporation and Chugai Pharmaceutical Co., Ltd. E Nakamura, K Narusawa, F Fukuda, H Matsumoto, K Nakai, T Sakata, T Yoshioka, and Y Fujino declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol and associated documents used in this study were reviewed and approved by the internal review board at each study site in accordance with the Declaration of Helsinki. All procedures in this study involving human participants were performed in accordance with the ethical standards of the institutional and\/or national research committee and with the Declaration of Helsinki and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all individual participants included in this study before initiating any procedures.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}