{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T17:22:43Z","timestamp":1696180963695},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2011,5,3]],"date-time":"2011-05-03T00:00:00Z","timestamp":1304380800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1007\/s00784-011-0556-5","type":"journal-article","created":{"date-parts":[[2011,5,2]],"date-time":"2011-05-02T10:48:18Z","timestamp":1304333298000},"page":"761-766","source":"Crossref","is-referenced-by-count":2,"title":["An unusual glycoform of human salivary mucin MG2"],"prefix":"10.1007","volume":"16","author":[{"given":"Rodrigo V.","family":"Soares","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gwynneth D.","family":"Offner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina A. L.","family":"Assis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karine C.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elton G.","family":"Zen\u00f3bio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,5,3]]},"reference":[{"key":"556_CR1","doi-asserted-by":"crossref","first-page":"20563","DOI":"10.1016\/S0021-9258(20)80762-5","volume":"268","author":"LA Bobek","year":"1993","unstructured":"Bobek LA, Tsai H, Biesbrock AR, Levine MJ (1993) Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7). J Biol Chem 268:20563\u201320569","journal-title":"J Biol Chem"},{"key":"556_CR2","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1006\/geno.1996.0049","volume":"31","author":"LA Bobek","year":"1996","unstructured":"Bobek LA, Liu J, Sait SN, Shows TB, Bobek YA, Levine MJ (1996) Structure and chromosomal localization of the human salivary mucin gene, MUC7. Genomics 31:277\u2013282","journal-title":"Genomics"},{"key":"556_CR3","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1177\/08959374000140011101","volume":"14","author":"GD Offner","year":"2000","unstructured":"Offner GD, Troxler RF (2000) Heterogeneity of high-molecular-weight human salivary mucins. Adv Dent Res 14:69\u201375","journal-title":"Adv Dent Res"},{"key":"556_CR4","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.2741\/Moniaux","volume":"6","author":"N Moniaux","year":"2001","unstructured":"Moniaux N, Escande F, Porchet N, Aubert JP, Batra SK (2001) Structural organization and classification of the human mucin genes. Front Biosci 6:1192\u20131206","journal-title":"Front Biosci"},{"key":"556_CR5","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1177\/00220345960750110201","volume":"75","author":"PA Nielsen","year":"1996","unstructured":"Nielsen PA, Mandel U, Therkildsen MH, Clausen H (1996) Differential expression of human high-molecular-weight salivary mucin (MG1) and low-molecular-weight salivary mucin (MG2). J Dent Res 75:1820\u20131826","journal-title":"J Dent Res"},{"key":"556_CR6","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/glycob\/7.3.413","volume":"7","author":"PA Nielsen","year":"1997","unstructured":"Nielsen PA, Bennett EP, Wandall HH, Therkildsen MH, Hannibal J, Clausen H (1997) Identification of a major human high molecular weight salivary mucin (MG1) as tracheobronchial mucin MUC5B. Glycobiology 7:413\u2013419","journal-title":"Glycobiology"},{"key":"556_CR7","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0003-9969(91)90004-E","volume":"36","author":"RE Cohen","year":"1991","unstructured":"Cohen RE, Aguirre A, Neiders ME, Levine MJ, Jones PC, Reddy MS, Haar JG (1991) Immunochemistry and immunogenicity of low molecular weight human salivary mucin. Arch Oral Biol 36:347\u2013356","journal-title":"Arch Oral Biol"},{"key":"556_CR8","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1023\/A:1006955604501","volume":"15","author":"SH Khan","year":"1998","unstructured":"Khan SH, Aguirre A, Bobek LA (1998) In-situ hybridization localized MUC7 mucin gene expression to the mucous acinar cells of human and MUC7-transgenic mouse salivary glands. Glycoconj J 15:1125\u20131132","journal-title":"Glycoconj J"},{"key":"556_CR9","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1177\/002215540305100109","volume":"51","author":"M Piludu","year":"2003","unstructured":"Piludu M, Rayment SA, Liu B, Offner GD, Oppenheim FG, Troxler RF, Hand AR (2003) Electron microscopic immunogold localizaton of salivary mucins MG1 and MG2 in human submandibular and sublingual glands. J Histochem Cytochem 51:69\u201379","journal-title":"J Histochem Cytochem"},{"key":"556_CR10","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1023\/A:1006978818555","volume":"15","author":"TL Gururaja","year":"1998","unstructured":"Gururaja TL, Ramasubbu N, Venugopalan P, Reddy MS, Ramalingam K, Levine MJ (1998) Structural features of the human salivary mucin, MUC7. Glycoconj J 15:457\u2013467","journal-title":"Glycoconj J"},{"key":"556_CR11","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0003-9861(87)90366-3","volume":"258","author":"RE Loomis","year":"1987","unstructured":"Loomis RE, Prakobphol A, Levine MJ, Reddy MS, Jones PC (1987) Biochemical and biophysical comparison of two mucins from human submandibular-sublingual saliva. Arch Biochem Biophys 258:452\u2013464","journal-title":"Arch Biochem Biophys"},{"key":"556_CR12","doi-asserted-by":"crossref","first-page":"4916","DOI":"10.1021\/bi972612a","volume":"37","author":"A Prakobphol","year":"1998","unstructured":"Prakobphol A, Thomsson KA, Hansson GC, Rosen SD, Singer MS, Phillips NJ, Medzihradszky KF, Burlingame AL, Leffler H, Fisher SJ (1998) Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity. Biochemistry 37:4916\u20134927","journal-title":"Biochemistry"},{"key":"556_CR13","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1042\/bj2800341","volume":"280","author":"N Ramasubbu","year":"1991","unstructured":"Ramasubbu N, Reddy MS, Bergey EJ, Haraszthy GG, Soni SD, Levine MJ (1991) Large-scale purification and characterization of the major phosphoproteins and mucins of human submandibular-sublingual saliva. Biochem J 280:341\u2013352","journal-title":"Biochem J"},{"key":"556_CR14","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1177\/00220345870660080201","volume":"66","author":"LM Collins","year":"1987","unstructured":"Collins LM, Dawes C (1987) The surface area of the adult human mouth and thickness of the salivary filmcovering the teeth and oral mucosa. J Dent Res 66:1300\u20131302","journal-title":"J Dent Res"},{"key":"556_CR15","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1146\/annurev.ph.57.030195.002555","volume":"57","author":"LA Tabak","year":"1995","unstructured":"Tabak LA (1995) In defense of the oral cavity: structure, biosynthesis and function of salivary mucins. Annu Rev Physiol 57:547\u2013564","journal-title":"Annu Rev Physiol"},{"key":"556_CR16","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/S0003-9969(87)80013-4","volume":"32","author":"SJ Fisher","year":"1987","unstructured":"Fisher SJ, Prakobphol A, Kajisa L, Murray PA (1987) External radiolabelling of components of pellicle on human enamel and cementum. Arch Oral Biol 32:509\u2013517","journal-title":"Arch Oral Biol"},{"key":"556_CR17","doi-asserted-by":"crossref","first-page":"5300","DOI":"10.1074\/jbc.M206333200","volume":"278","author":"Y Yao","year":"2003","unstructured":"Yao Y, Berg EA, Costello CE, Troxler RF, Oppenheim FG (2003) Identification of protein components in human acquired enamel pellicle and whole saliva using novel proteomics approaches. J Biol Chem 278:5300\u20135308","journal-title":"J Biol Chem"},{"key":"556_CR18","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0167-4838(99)00034-5","volume":"1431","author":"TL Gururaja","year":"1999","unstructured":"Gururaja TL, Levine JH, Tran DT, Naganagowda GA, Ramalingam K, Ramasubbu N, Levine MJ (1999) Candidacidal activity prompted by N-terminus histatin-like domain of human salivary mucin (MUC7). Biochim Biophys Acta 1431:107\u2013119","journal-title":"Biochim Biophys Acta"},{"key":"556_CR19","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1042\/0264-6021:3450557","volume":"345","author":"B Liu","year":"2000","unstructured":"Liu B, Rayment SA, Gyurko C, Oppenheim FG, Offner GD, Troxler RF (2000) The recombinant N-terminal region of human salivary mucin MG2 (MUC7) contains a binding domain for oral Streptococci and exhibits candidacidal activity. Biochem J 345:557\u2013564","journal-title":"Biochem J"},{"key":"556_CR20","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1034\/j.1600-0765.2002.01005.x","volume":"37","author":"B Liu","year":"2002","unstructured":"Liu B, Rayment SA, Soares RV, Oppenheim FG, Offner GD, Fives-Taylor P, Troxler RF (2002) Interaction of human salivary mucin MG2, its recombinant N-terminal region and a synthetic peptide with Actinobacillus actinomycetemcomitans. J Periodontal Res 37:416\u2013424","journal-title":"J Periodontal Res"},{"key":"556_CR21","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/10454411930040030901","volume":"4","author":"MS Reddy","year":"1993","unstructured":"Reddy MS, Levine MJ, Paranchych W (1993) Low-molecular-mass human salivary mucin, MG2: structure and binding of Pseudomonas aeruginosa. Crit Rev Oral Biol Med 4:315\u2013323","journal-title":"Crit Rev Oral Biol Med"},{"key":"556_CR22","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/BF00393572","volume":"70","author":"J Groenink","year":"1996","unstructured":"Groenink J, Ligtenberg AJ, Veerman EC, Bolscher JG, Nieuw Amerongen AV (1996) Interaction of the salivary low-molecular-weight mucin (MG2) with Actinobacillus actinomycetemcomitans. Antonie Leeuwenhoek 70:79\u201387","journal-title":"Antonie Leeuwenhoek"},{"key":"556_CR23","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1006\/abbi.1999.1141","volume":"364","author":"B Liu","year":"1999","unstructured":"Liu B, Rayment S, Oppenheim FG, Troxler RF (1999) Isolation of human salivary mucin MG2 by a novel method and characterization of its interactions with oral bacteria. Arch Biochem Biophys 364:286\u2013293","journal-title":"Arch Biochem Biophys"},{"key":"556_CR24","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1177\/00220345920710090501","volume":"71","author":"JL Jensen","year":"1992","unstructured":"Jensen JL, Lamkin MS, Oppenheim FG (1992) Adsorption of human salivary proteins to hydroxyapatite: a comparison between whole saliva and glandular salivary secretions. J Dent Res 71:1569\u20131576","journal-title":"J Dent Res"},{"key":"556_CR25","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/S0003-9969(00)00026-1","volume":"45","author":"CA Francis","year":"2000","unstructured":"Francis CA, Hector MP, Proctor GB (2000) Precipitation of specific proteins by freeze-thawing of human saliva. Arch Oral Biol 45:601\u2013660","journal-title":"Arch Oral Biol"},{"key":"556_CR26","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","volume":"227","author":"UK Laemmli","year":"1970","unstructured":"Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680\u2013685","journal-title":"Nature"},{"key":"556_CR27","doi-asserted-by":"crossref","first-page":"1765","DOI":"10.1177\/00220345000790100601","volume":"79","author":"SA Rayment","year":"2000","unstructured":"Rayment SA, Liu B, Offner GD, Oppenheim FG, Troxler RF (2000) Immunoquantification of human salivary mucins MG1 and MG2 in stimulated whole saliva: factors influencing mucin levels. J Dent Res 79:1765\u20131772","journal-title":"J Dent Res"},{"key":"556_CR28","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1042\/bst0060607","volume":"6","author":"M Mantle","year":"1978","unstructured":"Mantle M, Allen A (1978) A colorimetric assay for glycoproteins based on the periodic acid\/Schiff stain. Biochem Soc Trans 6:607\u2013609","journal-title":"Biochem Soc Trans"},{"key":"556_CR29","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1177\/00220345010800062101","volume":"80","author":"SA Rayment","year":"2001","unstructured":"Rayment SA, Liu B, Soares RV, Offner GD, Oppenheim FG, Troxler RF (2001) The effects of duration and intensity of stimulation on total protein and mucin concentrations in resting and stimulated whole saliva. J Dent Res 80:1584\u20131587","journal-title":"J Dent Res"},{"key":"556_CR30","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0003-9969(02)00171-1","volume":"48","author":"L Becerra","year":"2003","unstructured":"Becerra L, Soares RV, Bruno LS, Siqueira CC, Oppenheim FG, Offner GD, Troxler RF (2003) Patterns of secretion of mucins and non-mucin glycoproteins in human submandibular\/sublingual secretion. Arch Oral Biol 48:147\u2013154","journal-title":"Arch Oral Biol"},{"key":"556_CR31","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1177\/154405910308200613","volume":"82","author":"RV Soares","year":"2003","unstructured":"Soares RV, Siqueira CC, Bruno LS, Oppenheim FG, Offner GD, Troxler RF (2003) MG2 and lactoferrin form a heterotypic complex in salivary secretions. J Dent Res 82:471\u2013475","journal-title":"J Dent Res"},{"key":"556_CR32","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.archoralbio.2003.11.007","volume":"49","author":"RV Soares","year":"2004","unstructured":"Soares RV, Lin T, Siqueira CC, Bruno LS, Li X, Oppenheim FG, Offner G, Troxler RF (2004) Salivary micelles: identification of complexes containing MG2, sIgA, lactoferrin, amylase, glycosylated proline-rich protein and lysozyme. Arch Oral Biol 49:337\u2013343","journal-title":"Arch Oral Biol"},{"key":"556_CR33","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.bbamcr.2005.08.007","volume":"1746","author":"LS Bruno","year":"2005","unstructured":"Bruno LS, Li X, Wang L, Soares RV, Siqueira CC, Oppenheim FG, Troxler RF, Offner GD (2005) Two-hybrid analysis of human salivary mucin MUC7 interactions. Biochim Biophys Acta 1746:65\u201372","journal-title":"Biochim Biophys Acta"},{"key":"556_CR34","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1023\/A:1018587031814","volume":"14","author":"AR Biesbrock","year":"1997","unstructured":"Biesbrock AR, Bobek LA, Levine MJ (1997) MUC7 gene expression and genetic polymorphism. Glycoconj J 14:415\u2013422","journal-title":"Glycoconj J"},{"key":"556_CR35","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/sj.ejhg.5200642","volume":"9","author":"HJ Kirkbride","year":"2001","unstructured":"Kirkbride HJ, Bolscher JG, Nazmi K, Vinall LE, Nash MW, Moss FM, Mitchell DM, Swallow DM (2001) Genetic polymorphism of MUC7: allele frequencies and association with asthma. Eur J Hum Genet 9:347\u2013354","journal-title":"Eur J Hum Genet"},{"key":"556_CR36","first-page":"27","volume-title":"Saliva and oral health","author":"C Dawes","year":"1996","unstructured":"Dawes C (1996) Factors influencing salivary flow rate and composition. In: Edgar WM, O\u2019Mullane DM (eds) Saliva and oral health, 2nd edn. British Dent Association, London, pp 27\u201341","edition":"2"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-011-0556-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00784-011-0556-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-011-0556-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T12:39:16Z","timestamp":1637584756000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00784-011-0556-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,3]]},"references-count":36,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["556"],"URL":"https:\/\/doi.org\/10.1007\/s00784-011-0556-5","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,3]]}}}