{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T21:18:39Z","timestamp":1760908719890},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2011,5,17]],"date-time":"2011-05-17T00:00:00Z","timestamp":1305590400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1007\/s00784-011-0563-6","type":"journal-article","created":{"date-parts":[[2011,5,16]],"date-time":"2011-05-16T06:16:18Z","timestamp":1305526578000},"page":"879-887","source":"Crossref","is-referenced-by-count":9,"title":["Enterococcus faecalis affects the proliferation and differentiation of ovine osteoblast-like cells"],"prefix":"10.1007","volume":"16","author":[{"given":"Lamprini","family":"Karygianni","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margit","family":"Wiedmann-Al-Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcnter","family":"Finkenzeller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Sauerbier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Wolkewitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elmar","family":"Hellwig","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Al-Ahmad","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,5,17]]},"reference":[{"key":"563_CR1","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1128\/CMR.7.4.462","volume":"7","author":"BD Jett","year":"1994","unstructured":"Jett BD, Huycke MM, Gilmore MS (1994) Virulence of enterococci. Clin Microbiol Rev 7:462\u2013478","journal-title":"Clin Microbiol Rev"},{"key":"563_CR2","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1601-1546.2003.00040.x","volume":"6","author":"I Portenier","year":"2004","unstructured":"Portenier I, Waltimo TMT, Haapasalo M (2004) Enterococcus faecalis\u2014the root canal survivor and \u2018star\u2019 in post-treatment disease. Endod Topics 6:135\u2013159","journal-title":"Endod Topics"},{"key":"563_CR3","first-page":"235","volume":"31","author":"C Pirani","year":"2008","unstructured":"Pirani C, Bertacci A, Cavrini F, Foschi F, Acquaviva GL, Prati C, Sambri V (2008) Recovery of Enterococcus faecalis in root canal lumen of patients with primary and secondary endodontic lesions. New Microbiol 31:235\u2013240","journal-title":"New Microbiol"},{"key":"563_CR4","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.joen.2008.01.016","volume":"34","author":"BP Gomes","year":"2008","unstructured":"Gomes BP, Pinheiro ET, Jacinto RC, Zaia AA, Ferraz CC, Souza-Filho FJ (2008) Microbial analysis of canals of root-filled teeth with periapical lesions using polymerase chain reaction. J Endod 34:537\u2013540","journal-title":"J Endod"},{"key":"563_CR5","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1590\/S1678-77572009000500004","volume":"17","author":"SM Ozbek","year":"2009","unstructured":"Ozbek SM, Ozbek A, Erdorgan AS (2009) Analysis of Enterococcus faecalis in samples from Turkish patients with primary endodontic infections and failed endodontic treatment by real-time PCR SYBR green method. J Appl Oral Sci 17:370\u2013374","journal-title":"J Appl Oral Sci"},{"key":"563_CR6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1046\/j.1365-2591.2002.00504.x","volume":"35","author":"M Evans","year":"2002","unstructured":"Evans M, Davies JK, Sundqvist G, Figdor D (2002) Mechanisms involved in the resistance of Enterococcus faecalis to calcium hydroxide. Int Endod J 35:221\u2013228","journal-title":"Int Endod J"},{"key":"563_CR7","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/j.1365-2591.2004.00752.x","volume":"37","author":"CE Radcliffe","year":"2004","unstructured":"Radcliffe CE, Potouridou L, Qureshi R, Habahbeh N, Qualtrough A, Worthington H, Drucker DB (2004) Antimicrobial activity of varying concentrations of sodium hypochlorite on the endodontic microorganisms Actinomyces israelii, A. naeslundii, Candida albicans and Enterococcus faecalis. Int Endod J 37:438\u2013446","journal-title":"Int Endod J"},{"key":"563_CR8","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.joen.2010.04.013","volume":"36","author":"RJ Delgado","year":"2010","unstructured":"Delgado RJ, Gasparoto TH, Sipert CR, Pinheiro CR, Moraes IG, Garcia RB, Bramante CM, Campanelli AP, Bernardineli N (2010) Antimicrobial effects of calcium hydroxide and chlorhexidine on Enterococcus faecalis. J Endod 36:1389\u20131393","journal-title":"J Endod"},{"key":"563_CR9","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1034\/j.1399-302x.2000.150507.x","volume":"15","author":"G Dahlen","year":"2000","unstructured":"Dahlen G, Samuelsson W, Molander A, Reit C (2000) Identification and antimicrobial susceptibility of enterococci isolated from the root canal. Oral Microbiol Immunol 15:309\u2013312","journal-title":"Oral Microbiol Immunol"},{"key":"563_CR10","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1128\/JCM.00388-09","volume":"47","author":"J Sun","year":"2009","unstructured":"Sun J, Song X, Kristiansen BE, Kjaereng A, Willems RJ, Eriksen HM, Sundsfjord A, Sollid JE (2009) Occurrence, population structure, and antimicrobial resistance of enterococci in marginal and apical periodontitis. J Clin Microbiol 47:2218\u20132225","journal-title":"J Clin Microbiol"},{"key":"563_CR11","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1111\/j.1365-2591.2008.01445.x","volume":"41","author":"P Chivatxaranukul","year":"2008","unstructured":"Chivatxaranukul P, Dashper SG, Messer HH (2008) Dentinal tubule invasion and adherence by Enterococcus faecalis. Int Endod J 41:873\u2013882","journal-title":"Int Endod J"},{"key":"563_CR12","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1097\/00004770-200210000-00003","volume":"28","author":"JW Distel","year":"2002","unstructured":"Distel JW, Hatton JF, Gillespie MJ (2002) Biofilm formation in medicated root canals. J Endod 28:689\u2013693","journal-title":"J Endod"},{"key":"563_CR13","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1111\/j.1600-0722.2004.00165.x","volume":"112","author":"N Takemura","year":"2004","unstructured":"Takemura N, Noiri Y, Ehara A, Kawahara T, Noguchi N, Ebisu S (2004) Single species biofilm-forming ability of root canal isolates on gutta-percha points. Eur J Oral Sci 112:523\u2013529","journal-title":"Eur J Oral Sci"},{"key":"563_CR14","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1128\/AEM.66.5.1953-1959.2000","volume":"66","author":"C Signoretto","year":"2000","unstructured":"Signoretto C, Lleo MM, Tafi MC, Canepari P (2000) Cell wall chemical composition of Enterococcus faecalis in the viable but nonculturable state. Appl Environ Microbiol 66:1953\u20131959","journal-title":"Appl Environ Microbiol"},{"key":"563_CR15","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/mpat.2000.0429","volume":"30","author":"E Rozdzinski","year":"2001","unstructured":"Rozdzinski E, Marre R, Susa M, Wirth R, Muscholl-Silberhorn A (2001) Aggregation substance-mediated adherence of Enterococcus faecalis to immobilized extracellular matrix proteins. Microb Pathog 30:211\u2013220","journal-title":"Microb Pathog"},{"key":"563_CR16","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1099\/jmm.0.05039-0","volume":"52","author":"YL Low","year":"2003","unstructured":"Low YL, Jakubovics NS, Flatman JC, Jenkinson HF, Smith AW (2003) Manganese-dependent regulation of the endocarditis-associated virulence factor EfaA of Enterococcus faecalis. J Med Microbiol 52:113\u2013119","journal-title":"J Med Microbiol"},{"key":"563_CR17","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1177\/154411130401500506","volume":"15","author":"G Kayaoglu","year":"2004","unstructured":"Kayaoglu G, Orstavik D (2004) Virulence factors of Enterococcus faecalis: relationship to endodontic disease. Crit Rev Oral Biol Med 15:308\u2013320","journal-title":"Crit Rev Oral Biol Med"},{"key":"563_CR18","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/j.1601-1546.2003.00054.x","volume":"6","author":"G Sundqvist","year":"2003","unstructured":"Sundqvist G, Figdor D (2003) Life as an endodontic pathogen. Endod Topics 6:3\u201328","journal-title":"Endod Topics"},{"key":"563_CR19","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1016\/j.joen.2008.07.028","volume":"34","author":"JF Siqueira Jr","year":"2008","unstructured":"Siqueira JF Jr, Rocas IN (2008) Clinical implications and microbiology of bacterial persistence after treatment procedures. J Endod 34:1291\u20131301, e1293","journal-title":"J Endod"},{"key":"563_CR20","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1177\/0022034509346549","volume":"88","author":"JF Siqueira Jr","year":"2009","unstructured":"Siqueira JF Jr, Rocas IN (2009) Diversity of endodontic microbiota revisited. J Dent Res 88:969\u2013981","journal-title":"J Dent Res"},{"key":"563_CR21","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.joen.2007.01.012","volume":"33","author":"JF Schirrmeister","year":"2007","unstructured":"Schirrmeister JF, Liebenow AL, Braun G, Wittmer A, Hellwig E, Al-Ahmad A (2007) Detection and eradication of microorganisms in root-filled teeth associated with periradicular lesions: an in vivo study. J Endod 33:536\u2013540","journal-title":"J Endod"},{"key":"563_CR22","doi-asserted-by":"crossref","first-page":"4046","DOI":"10.1128\/IAI.63.10.4046-4053.1995","volume":"63","author":"RF Noel Jr","year":"1995","unstructured":"Noel RF Jr, Sato TT, Mendez C, Johnson MC, Pohlman TH (1995) Activation of human endothelial cells by viable or heat-killed gram-negative bacteria requires soluble CD14. Infect Immun 63:4046\u20134053","journal-title":"Infect Immun"},{"key":"563_CR23","first-page":"943","volume":"47","author":"J Carmichael","year":"1987","unstructured":"Carmichael J, DeGraff WG, Gazdar AF, Minna JD, Mitchell JB (1987) Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of radiosensitivity. Cancer Res 47:943\u2013946","journal-title":"Cancer Res"},{"key":"563_CR24","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1002\/1097-4644(20010315)80:4<532::AID-JCB1007>3.0.CO;2-B","volume":"80","author":"JS Blum","year":"2001","unstructured":"Blum JS, Li RH, Mikos AG, Barry MA (2001) An optimized method for the chemiluminescent detection of alkaline phosphatase levels during osteodifferentiation by bone morphogenetic protein 2. J Cell Biochem 80:532\u2013537","journal-title":"J Cell Biochem"},{"key":"563_CR25","first-page":"26","volume-title":"Methods of calcified tissue preparation","author":"RK Schenk","year":"1984","unstructured":"Schenk RK, Olah AJ, Hermann W (1984) Preparation of calcified tissue for light microscopy. In: Dickson GR (ed) Methods of calcified tissue preparation. Elsevier Science, New York, pp 26\u201332"},{"key":"563_CR26","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1006\/abio.1999.4085","volume":"270","author":"J Winer","year":"1999","unstructured":"Winer J, Jung C, Shackel I, Williams P (1999) Development and validation of real-time quantitative reverse transcriptasepolymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal Biochem 270:41\u201349","journal-title":"Anal Biochem"},{"key":"563_CR27","first-page":"33","volume-title":"Applied mixed models in medicine","author":"H Brown","year":"1999","unstructured":"Brown H, Prescott R (1999) In: Barnett V (ed) Applied mixed models in medicine. John Wiley and Sons, Hoboken, pp 33\u201383"},{"key":"563_CR28","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1097\/BRS.0b013e3181a9c087","volume":"34","author":"HL Defino","year":"2009","unstructured":"Defino HL, da Silva Herrero CF, Crippa GE, Bellesini LS, Beloti MM, Rosa AL (2009) In vitro proliferation and osteoblastic phenotype expression of cells derived from human vertebral lamina and iliac crest. Spine (Phila Pa 1976) 34:1549\u20131553","journal-title":"Spine (Phila Pa 1976)"},{"key":"563_CR29","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1007\/s10856-007-3238-8","volume":"19","author":"SC Schmitt","year":"2008","unstructured":"Schmitt SC, Wiedmann-Al-Ahmad M, Kuschnierz J, Al-Ahmad A, Huebner U, Schmelzeisen R, Gutwald R (2008) Comparative in vitro study of the proliferation and growth of ovine osteoblast-like cells on various alloplastic biomaterials manufactured for augmentation and reconstruction of tissue or bone defects. J Mater Sci Mater Med 19:1441\u20131450","journal-title":"J Mater Sci Mater Med"},{"key":"563_CR30","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1002\/jbm.a.31416","volume":"83","author":"M Wagner","year":"2007","unstructured":"Wagner M, Kiapur N, Wiedmann-Al-Ahmad M, H\u00fcbner U, Al-Ahmad A, Sch\u00f6n R, Schmelzeisen R, M\u00fclhaupt R, Gellrich NC (2007) Comparative in vitro study of the cell proliferation of ovine and human osteoblast-like cells on conventionally an rapid prototyping produced scaffolds tailored for application as potential replacement material. J Biomed Mater Res A 83:1154\u20131164","journal-title":"J Biomed Mater Res A"},{"key":"563_CR31","doi-asserted-by":"crossref","first-page":"3319","DOI":"10.1016\/S0142-9612(02)00019-4","volume":"23","author":"M Wiedmann-Al-Ahmad","year":"2002","unstructured":"Wiedmann-Al-Ahmad M, Gutwald R, Lauer G, Hubner U, Schmelzeisen R (2002) How to optimize seeding and culturing of human osteoblast-like cells on various biomaterials. Biomaterials 23:3319\u20133328","journal-title":"Biomaterials"},{"key":"563_CR32","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s12223-009-0024-7","volume":"54","author":"SN Ostad","year":"2009","unstructured":"Ostad SN, Salarian AA, Ghahramani MH, Fazeli MR, Samadi N, Jamalifar H (2009) Live and heat-inactivated lactobacilli from feces inhibit Salmonella typhi and Escherichia coli adherence to Caco-2 cells. Folia Microbiol (Praha) 54:157\u2013160","journal-title":"Folia Microbiol (Praha)"},{"key":"563_CR33","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/j.joen.2009.04.013","volume":"35","author":"A Al-Ahmad","year":"2009","unstructured":"Al-Ahmad A, Muller N, Wiedmann-Al-Ahmad M, Sava I, Hubner J, Follo M, Schirrmeister J, Hellwig E (2009) Endodontic and salivary isolates of Enterococcus faecalis integrate into biofilm from human salivary bacteria cultivated in vitro. J Endod 35:986\u2013991","journal-title":"J Endod"},{"key":"563_CR34","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/(SICI)1097-4652(200002)182:2<232::AID-JCP12>3.0.CO;2-5","volume":"182","author":"A Elgavish","year":"2000","unstructured":"Elgavish A (2000) NF-kappaB activation mediates the response of a subpopulation of basal uroepithelial cells to a cell wall component of Enterococcus faecalis. J Cell Physiol 182:232\u2013238","journal-title":"J Cell Physiol"},{"key":"563_CR35","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.joen.2009.10.014","volume":"36","author":"CR Sipert","year":"2010","unstructured":"Sipert CR, Moraes IG, Bernardinelli N, Garcia RB, Bramante CM, Gasparoto TH, Figueira EA, Dionisio TJ, Campanelli AP, Oliveira SH, Cunha FQ, Santos CF (2010) Heat-killed Enterococcus faecalis alters nitric oxide and CXCL12 production but not CXCL8 and CCL3 production by cultured human dental pulp fibroblasts. J Endod 36:91\u201394","journal-title":"J Endod"},{"key":"563_CR36","doi-asserted-by":"crossref","first-page":"2317","DOI":"10.1016\/j.lfs.2004.04.026","volume":"75","author":"N Tanabe","year":"2004","unstructured":"Tanabe N, Ito-Kato E, Suzuki N, Nakayama A, Ogiso B, Maeno M, Ito K (2004) IL-1alpha affects mineralized nodule formation by rat osteoblasts. Life Sci 75:2317\u20132327","journal-title":"Life Sci"},{"key":"563_CR37","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1128\/IAI.67.6.2841-2846.1999","volume":"67","author":"H Kadono","year":"1999","unstructured":"Kadono H, Kido J, Kataoka M, Yamauchi N, Nagata T (1999) Inhibition of osteoblastic cell differentiation by lipopolysaccharide extract from Porphyromonas gingivalis. Infect Immun 67:2841\u20132846","journal-title":"Infect Immun"},{"key":"563_CR38","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/j.1600-0722.2008.00535.x","volume":"116","author":"HC Roberts","year":"2008","unstructured":"Roberts HC, Moseley R, Sloan AJ, Youde SJ, Waddington RJ (2008) Lipopolysaccharide alters decorin and biglycan synthesis in rat alveolar bone osteoblasts: consequences for bone repair during periodontal disease. Eur J Oral Sci 116:207\u2013216","journal-title":"Eur J Oral Sci"},{"key":"563_CR39","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1097\/00003086-199801000-00032","volume":"346","author":"UH Lerner","year":"1998","unstructured":"Lerner UH, Sundqvist G, Ohlin A, Rosenquist JB (1998) Bacteria inhibit biosynthesis of bone matrix proteins in human osteoblasts. Clin Orthop Relat Res 346:244\u2013254","journal-title":"Clin Orthop Relat Res"},{"key":"563_CR40","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1086\/508751","volume":"194","author":"M Verdrengh","year":"2006","unstructured":"Verdrengh M, Carlsten H, Ohlsson C, Tarkowski A (2006) Rapid systemic bone resorption during the course of Staphylococcus aureus-induced arthritis. J Infect Dis 194:1597\u20131600","journal-title":"J Infect Dis"},{"key":"563_CR41","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.yexcr.2004.01.004","volume":"295","author":"VV Iyer","year":"2004","unstructured":"Iyer VV, Kadakia TB, McCabe LR, Schwartz RC (2004) CCAAT\/enhancer-binding protein-beta has a role in osteoblast proliferation and differentiation. Exp Cell Res 295:128\u2013137","journal-title":"Exp Cell Res"},{"key":"563_CR42","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S1074-7613(00)80119-3","volume":"11","author":"O Takeuchi","year":"1999","unstructured":"Takeuchi O, Hoshino K, Kawai T, Sanjo H, Takada H, Ogawa T, Takeda K, Akira S (1999) Differential roles of TLR2 and 51TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11:443\u2013451","journal-title":"Immunity"},{"key":"563_CR43","doi-asserted-by":"crossref","first-page":"2880","DOI":"10.4049\/jimmunol.176.5.2880","volume":"176","author":"SH Durand","year":"2006","unstructured":"Durand SH, Flacher V, Rom\u00e9as A, Carrouel F, Colomb E, Vincent C, Magloire H, Couble ML, Bleicher F, Staquet MJ, Lebecque S, Farges JC (2006) Lipoteichoic acid increases TLR and functional chemokine expression while reducing dentin formation in in vitro differentiated human odontoblasts. J Immunol 176:2880\u20132887","journal-title":"J Immunol"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-011-0563-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00784-011-0563-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-011-0563-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T04:39:31Z","timestamp":1592541571000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00784-011-0563-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,5,17]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["563"],"URL":"https:\/\/doi.org\/10.1007\/s00784-011-0563-6","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,5,17]]}}}