{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T00:59:26Z","timestamp":1781917166382,"version":"3.54.5"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2012,10,5]],"date-time":"2012-10-05T00:00:00Z","timestamp":1349395200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1007\/s00784-012-0854-6","type":"journal-article","created":{"date-parts":[[2012,10,4]],"date-time":"2012-10-04T06:59:08Z","timestamp":1349333948000},"page":"1619-1625","source":"Crossref","is-referenced-by-count":22,"title":["The influence of parotid gland sparing on radiation damages of dental hard tissues"],"prefix":"10.1007","volume":"17","author":[{"given":"Jeremias","family":"Hey","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Seidel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramona","family":"Schweyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Paelecke-Habermann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dirk","family":"Vordermark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Gernhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Kuhnt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2012,10,5]]},"reference":[{"key":"854_CR1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/s00066-011-0011-1","volume":"188","author":"R Schweyen","year":"2012","unstructured":"Schweyen R, Hey J, Fr\u00e4nzel W, Vordermark D, Hildebrandt G, Kuhnt T (2012) Radiation-related caries: etiology and possible preventive strategies. What should the radiotherapist know? Strahlenther Onkol 188:21\u201328","journal-title":"Strahlenther Onkol"},{"key":"854_CR2","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1159\/000262007","volume":"28","author":"CJ Spak","year":"1994","unstructured":"Spak CJ, Johnson G, Ekstrand J (1994) Caries incidence, salivary flow rate and efficacy of fluoride gel treatment in irradiated patients. Caries Res 28:388\u2013393","journal-title":"Caries Res"},{"key":"854_CR3","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0167-8140(01)00449-2","volume":"61","author":"KS Chao","year":"2001","unstructured":"Chao KS, Majhail N, Huang CJ, Simpson JR, Perez CA, Haughey B, Spector G (2001) Intensity-modulated radiation therapy reduces late salivary toxicity without compromising tumor control in patients with oropharyngeal carcinoma: a comparison with conventional techniques. Radiother Oncol 61:275\u2013280","journal-title":"Radiother Oncol"},{"key":"854_CR4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s00520-002-0407-7","volume":"11","author":"SB Jensen","year":"2003","unstructured":"Jensen SB, Pedersen AM, Reibel J, Nauntofte B (2003) Xerostomia and hypofunction of the salivary glands in cancer therapy. Support Care Cancer 11:207\u2013225","journal-title":"Support Care Cancer"},{"key":"854_CR5","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1016\/S0360-3016(00)01441-3","volume":"49","author":"KS Chao","year":"2001","unstructured":"Chao KS, Deasy JO, Markman J, Haynie J, Perez CA, Purdy JA, Low DA (2001) A prospective study of salivary function sparing in patients with head-and-neck cancers receiving intensity-modulated or three-dimensional radiation therapy: initial results. Int J Radiat Oncol Biol Phys 49:907\u2013916","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"854_CR6","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0360-3016(03)01571-2","volume":"58","author":"MB Parliament","year":"2004","unstructured":"Parliament MB, Scrimger RA, Anderson SG, Kurien EC, Thompson HK, Field GC, Hanson J (2004) Preservation of oral health-related quality of life and salivary flow rates after inverse-planned intensity-modulated radiotherapy (IMRT) for head-and-neck cancer. Int J Radiat Oncol Biol Phys 58:663\u2013673","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"854_CR7","doi-asserted-by":"crossref","first-page":"e207","DOI":"10.1016\/j.ijrobp.2011.02.003","volume":"81","author":"DR Gomez","year":"2011","unstructured":"Gomez DR, Estilo CL, Wolden SL, Zelefsky MJ, Kraus DH, Wong RJ, Shaha AR, Shah JP, Mechalakos JG, Lee NY (2011) Correlation of osteoradionecrosis and dental events with dosimetric parameters in intensity-modulated radiation therapy for head-and-neck cancer. Int J Radiat Oncol Biol Phys 81:e207\u2013e213","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"854_CR8","doi-asserted-by":"crossref","first-page":"e11","DOI":"10.1016\/j.oraloncology.2008.04.004","volume":"45","author":"J Hey","year":"2009","unstructured":"Hey J, Setz J, Gerlach R, Janich M, Sehlleier S, Schaller HG, Gernhardt CR, Kuhnt T (2009) Parotid-gland sparing 3D conformal radiotherapy in patients with bilateral radiotherapy of the head and neck region\u2014results in clinical practice. Oral Oncol 45:e11\u2013e17","journal-title":"Oral Oncol"},{"key":"854_CR9","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/1748-717X-6-125","volume":"6","author":"J Hey","year":"2011","unstructured":"Hey J, Setz J, Gerlach R, Janich M, Hildebrandt G, Vordermark D, Gernhardt CR, Kuhnt T (2011) Parotid gland-recovery after radiotherapy in the head and neck region\u201436\u00a0months follow-up of a prospective clinical study. Radiat Oncol 6:125","journal-title":"Radiat Oncol"},{"key":"854_CR10","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s00066-006-1527-7","volume":"182","author":"T Kuhnt","year":"2006","unstructured":"Kuhnt T, Janich M, Gotz U, Gerlach R, Chiricuta IC, Hansgen G (2006) Presentation of a 3D conformal radiotherapy technique for head-and-neck tumors resulting in substantial protection of the parotid glands. Strahlenther Onkol 182:325\u2013330","journal-title":"Strahlenther Onkol"},{"key":"854_CR11","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s00066-006-1531-y","volume":"182","author":"D Georg","year":"2006","unstructured":"Georg D, Kroupa B, Georg P, Winkler P, Bogner J, Dieckmann K, P\u00f6tter R (2006) Inverse planning\u2014a comparative intersystem and interpatient constraint study. Strahlenther Onkol 182:473\u2013480","journal-title":"Strahlenther Onkol"},{"key":"854_CR12","first-page":"1","volume":"1","author":"International Commission on Radiation Units and Measurements","year":"1993","unstructured":"International Commission on Radiation Units and Measurements (1993) ICRU 50: prescribing and reporting photon beam therapy. Inc ICRU News 1:1\u201372","journal-title":"Inc ICRU News"},{"key":"854_CR13","first-page":"1","volume":"1","author":"International Commission on Radiation Units and Measurements","year":"1999","unstructured":"International Commission on Radiation Units and Measurements (1999) ICRU 62: prescribing, recording and reporting photon beam therapy (supplement to ICRU Report 50). Inc ICRU News 1:1\u20138","journal-title":"Inc ICRU News"},{"key":"854_CR14","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0360-3016(89)90462-8","volume":"17","author":"JT Lyman","year":"1989","unstructured":"Lyman JT, Wolbarst AB (1989) Optimization of radiation therapy, IV: a dose-volume histogram reduction algorithm. Int J Radiat Oncol Biol Phys 17:433\u2013436","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"854_CR15","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0167-8140(01)00427-3","volume":"61","author":"FR Burlage","year":"2001","unstructured":"Burlage FR, Coppes RP, Meertens H, Stokman MA, Vissink A (2001) Parotid and submandibular\/sublingual salivary flow during high dose radiotherapy. Radiother Oncol 61:271\u2013274","journal-title":"Radiother Oncol"},{"key":"854_CR16","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1177\/00220345870660S207","volume":"66","author":"C Dawes","year":"1987","unstructured":"Dawes C (1987) Physiological factors affecting salivary flow rate, oral sugar clearance, and the sensation of dry mouth in man. J Dent Res 66:648\u2013653","journal-title":"J Dent Res"},{"key":"854_CR17","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1600-0528.1999.tb02018.x","volume":"27","author":"DJ Witter","year":"1999","unstructured":"Witter DJ, van Palenstein Helderman WH, Creugers NH, Kayser AF (1999) The shortened dental arch concept and its implications for oral health care. Community Dent Oral Epidemiol 27:249\u2013258","journal-title":"Community Dent Oral Epidemiol"},{"key":"854_CR18","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/S1470-2045(06)70658-1","volume":"7","author":"AM Kielbassa","year":"2006","unstructured":"Kielbassa AM, Hinkelbein W, Hellwig E, Meyer-Luckel H (2006) Radiation-related damage to dentition. Lancet Oncol 7:326\u2013335","journal-title":"Lancet Oncol"},{"key":"854_CR19","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/PL00002390","volume":"177","author":"KA Grotz","year":"2001","unstructured":"Grotz KA, Riesenbeck D, Brahm R, Seegenschmiedt MH, Al-Nawas B, Dorr W, Kutzner J, Willich N, Thelen M, Wagner W (2001) Chronic radiation effects on dental hard tissue (radiation caries). Classification and therapeutic strategies. Strahlenther Onkol 177:96\u2013104","journal-title":"Strahlenther Onkol"},{"key":"854_CR20","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1078\/0939-3889-00307","volume":"16","author":"W Franzel","year":"2006","unstructured":"Franzel W, Gerlach R, Hein HJ, Schaller HG (2006) Effect of tumor therapeutic irradiation on the mechanical properties of teeth tissue. Z Med Phys 16:148\u2013154","journal-title":"Z Med Phys"},{"key":"854_CR21","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.prro.2011.03.003","volume":"1","author":"MP Walker","year":"2011","unstructured":"Walker MP, Wichman B, Cheng AL, Coster J, Williams KB (2011) Impact of radiotherapy dose on dentition breakdown in head and neck cancer patients. Pract Radiat Oncol 1:142\u2013148","journal-title":"Pract Radiat Oncol"},{"key":"854_CR22","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1034\/j.1600-0722.2000.108003214.x","volume":"108","author":"AM Kielbassa","year":"2000","unstructured":"Kielbassa AM (2000) In situ induced demineralization in irradiated and non-irradiated human dentin. Eur J Oral Sci 108:214\u2013221","journal-title":"Eur J Oral Sci"},{"key":"854_CR23","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1159\/000091059","volume":"40","author":"AM Kielbassa","year":"2006","unstructured":"Kielbassa AM, Hellwig E, Meyer-Lueckel H (2006) Effects of irradiation on in situ remineralization of human and bovine enamel demineralized in vitro. Caries Res 40:130\u2013135","journal-title":"Caries Res"},{"key":"854_CR24","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1007\/s00784-011-0612-1","volume":"16","author":"J Karbach","year":"2012","unstructured":"Karbach J, Walter C, Al-Nawas B (2012) Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation. Clin Oral Investig 16:1305\u20131312","journal-title":"Clin Oral Investig"},{"key":"854_CR25","doi-asserted-by":"crossref","first-page":"1874","DOI":"10.1177\/00220345000790111001","volume":"79","author":"EM Ghezzi","year":"2000","unstructured":"Ghezzi EM, Lange LA, Ship JA (2000) Determination of variation of stimulated salivary flow rates. J Dent Res 79:1874\u20131878","journal-title":"J Dent Res"},{"key":"854_CR26","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1111\/j.1600-0722.1996.tb00090.x","volume":"104","author":"EC Veerman","year":"1996","unstructured":"Veerman EC, van den Keybus PA, Vissink A, Nieuw Amerongen AV (1996) Human glandular salivas: their separate collection and analysis. Eur J Oral Sci 104:346\u2013352","journal-title":"Eur J Oral Sci"},{"key":"854_CR27","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1007\/s00066-002-0961-4","volume":"178","author":"KT Beer","year":"2002","unstructured":"Beer KT, Zehnder D, Lussi A, Greiner RH (2002) Sparing of contralateral major salivary glands has a significant effect on oral health in patients treated with radical radiotherapy of head and neck tumors. Strahlenther Onkol 178:722\u2013726","journal-title":"Strahlenther Onkol"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-012-0854-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00784-012-0854-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-012-0854-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,14]],"date-time":"2020-07-14T12:40:15Z","timestamp":1594730415000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00784-012-0854-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,5]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["854"],"URL":"https:\/\/doi.org\/10.1007\/s00784-012-0854-6","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,5]]}}}