{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T16:59:13Z","timestamp":1791565153885,"version":"4.3.4"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T00:00:00Z","timestamp":1438905600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T00:00:00Z","timestamp":1438905600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1007\/s00784-015-1553-x","type":"journal-article","created":{"date-parts":[[2015,8,6]],"date-time":"2015-08-06T01:17:47Z","timestamp":1438823867000},"page":"669-674","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Relationship between periodontal parameters and plasma cytokine profiles in pregnant woman with preterm birth or low birth weight"],"prefix":"10.1007","volume":"20","author":[{"given":"Francisco","family":"Mesa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Pozo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"O\u2019Valle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Puertas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Magan-Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Rosel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Bravo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,8,7]]},"reference":[{"issue":"9862","key":"1553_CR1","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/S0140-6736(12)61856-X","volume":"381","author":"HH Chang","year":"2013","unstructured":"Chang HH, Larson J, Blencowe H, Spong CY, Howson CP, Cairns-Smith S, Lackritz EM, Lee SK, Mason E, Serazin AC, Walani S, Simpson JL, Lawn JE (2013) Preventing preterm births: analysis of trends and potential reductions with interventions in 39 countries with very high human development index. Lancet 381(9862):223\u2013234. doi:\n                    10.1016\/S0140-6736(12)61856-X","journal-title":"Lancet"},{"issue":"Suppl 14","key":"1553_CR2","doi-asserted-by":"publisher","first-page":"S164","DOI":"10.1111\/jcpe.12083","volume":"40","author":"M Sanz","year":"2013","unstructured":"Sanz M, Kornman K, Working group 3 of joint EFPAAPw (2013) Periodontitis and adverse pregnancy outcomes: consensus report of the Joint EFP\/AAP Workshop on Periodontitis and Systemic Diseases. J Clin Periodontol 40(Suppl 14):S164\u2013169. doi:\n                    10.1111\/jcpe.12083","journal-title":"J Clin Periodontol"},{"issue":"9","key":"1553_CR3","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1111\/j.1600-051X.2011.01755.x","volume":"38","author":"L Chambrone","year":"2011","unstructured":"Chambrone L, Guglielmetti MR, Pannuti CM, Chambrone LA (2011) Evidence grade associating periodontitis to preterm birth and\/or low birth weight: I. A systematic review of prospective cohort studies. J Clin Periodontol 38(9):795\u2013808. doi:\n                    10.1111\/j.1600-051X.2011.01755.x","journal-title":"J Clin Periodontol"},{"issue":"8 Suppl","key":"1553_CR4","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1111\/j.1600-051X.2008.01284.x","volume":"35","author":"G Wimmer","year":"2008","unstructured":"Wimmer G, Pihlstrom BL (2008) A critical assessment of adverse pregnancy outcome and periodontal disease. J Clin Periodontol 35(8 Suppl):380\u2013397. doi:\n                    10.1111\/j.1600-051X.2008.01284.x","journal-title":"J Clin Periodontol"},{"issue":"8 Suppl","key":"1553_CR5","doi-asserted-by":"publisher","first-page":"1585","DOI":"10.1902\/jop.2008.080183","volume":"79","author":"D Graves","year":"2008","unstructured":"Graves D (2008) Cytokines that promote periodontal tissue destruction. J Periodontol 79(8 Suppl):1585\u20131591. doi:\n                    10.1902\/jop.2008.080183","journal-title":"J Periodontol"},{"issue":"1","key":"1553_CR6","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1111\/j.1600-0765.2009.01204.x","volume":"45","author":"DH Thunell","year":"2010","unstructured":"Thunell DH, Tymkiw KD, Johnson GK, Joly S, Burnell KK, Cavanaugh JE, Brogden KA, Guthmiller JM (2010) A multiplex immunoassay demonstrates reductions in gingival crevicular fluid cytokines following initial periodontal therapy. J Periodontal Res 45(1):148\u2013152. doi:\n                    10.1111\/j.1600-0765.2009.01204.x","journal-title":"J Periodontal Res"},{"issue":"1","key":"1553_CR7","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.cyto.2011.12.015","volume":"58","author":"T Fiorini","year":"2012","unstructured":"Fiorini T, Vianna P, Weidlich P, Musskopf ML, Moreira CH, Chies JA, Rosing CK, Oppermann RV, Susin C (2012) Relationship between cytokine levels in serum and gingival crevicular fluid (GCF) in pregnant women. Cytokine 58(1):34\u201339. doi:\n                    10.1016\/j.cyto.2011.12.015","journal-title":"Cytokine"},{"issue":"12","key":"1553_CR8","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1902\/jop.2011.100740","volume":"82","author":"T Sert","year":"2011","unstructured":"Sert T, Kirzioglu FY, Fentoglu O, Aylak F, Mungan T (2011) Serum placental growth factor, vascular endothelial growth factor, soluble vascular endothelial growth factor receptor-1 and -2 levels in periodontal disease, and adverse pregnancy outcomes. J Periodontol 82(12):1735\u20131748. doi:\n                    10.1902\/jop.2011.100740","journal-title":"J Periodontol"},{"issue":"11","key":"1553_CR9","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1902\/jop.2009.090236","volume":"80","author":"BS Michalowicz","year":"2009","unstructured":"Michalowicz BS, Novak MJ, Hodges JS, DiAngelis A, Buchanan W, Papapanou PN, Mitchell DA, Ferguson JE, Lupo V, Bofill J, Matseoane S, Steffen M, Ebersole JL (2009) Serum inflammatory mediators in pregnancy: changes after periodontal treatment and association with pregnancy outcomes. J Periodontol 80(11):1731\u20131741. doi:\n                    10.1902\/jop.2009.090236","journal-title":"J Periodontol"},{"issue":"Suppl 14","key":"1553_CR10","doi-asserted-by":"publisher","first-page":"S170","DOI":"10.1111\/jcpe.12082","volume":"40","author":"PN Madianos","year":"2013","unstructured":"Madianos PN, Bobetsis YA, Offenbacher S (2013) Adverse pregnancy outcomes (APOs) and periodontal disease: pathogenic mechanisms. J Clin Periodontol 40(Suppl 14):S170\u2013S180. doi:\n                    10.1111\/jcpe.12082","journal-title":"J Clin Periodontol"},{"key":"1553_CR11","unstructured":"Cohen J (1988) Statistical power analysis for the behavioural sciences. 2\u00b0 Ed. edn. Lawrence Erlbaum Associates, New Jersey"},{"issue":"1","key":"1553_CR12","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1590\/S1135-57272001000100003","volume":"75","author":"E Regidor","year":"2001","unstructured":"Regidor E, de Trabajo de la Grupo SEE (2001) The Goldthorpe Social Class Classification: reference framework for a proposal for the measurement of social class by the Working Group of the Spanish Society of Epidemiology. Rev Esp Salud Publica 75(1):13\u201322","journal-title":"Rev Esp Salud Publica"},{"issue":"1","key":"1553_CR13","doi-asserted-by":"publisher","first-page":"159","DOI":"10.2307\/2529310","volume":"33","author":"JR Landis","year":"1977","unstructured":"Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33(1):159\u2013174","journal-title":"Biometrics"},{"issue":"4","key":"1553_CR14","first-page":"229","volume":"25","author":"J Ainamo","year":"1975","unstructured":"Ainamo J, Bay I (1975) Problems and proposals for recording gingivitis and plaque. Int Dent J 25(4):229\u2013235","journal-title":"Int Dent J"},{"issue":"1","key":"1553_CR15","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1177\/154405910208100113","volume":"81","author":"NJ Lopez","year":"2002","unstructured":"Lopez NJ, Smith PC, Gutierrez J (2002) Higher risk of preterm birth and low birth weight in women with periodontal disease. J Dent Res 81(1):58\u201363","journal-title":"J Dent Res"},{"key":"1553_CR16","unstructured":"Dom\u00e9nech Massons J, Sarri\u00e1 Arrufat A (1993) An\u00e1lisis multivariante en ciencias de la salud. Construcci\u00f3n de un modelo de regresi\u00f3n m\u00faltiple [In Spanish]. Editorial Gr\u00e1ficas SIGNO, Barcelona"},{"key":"1553_CR17","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/1471-2172-11-59","volume":"11","author":"A Szarka","year":"2010","unstructured":"Szarka A, Rigo J Jr, Lazar L, Beko G, Molvarec A (2010) Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol 11:59. doi:\n                    10.1186\/1471-2172-11-59","journal-title":"BMC Immunol"},{"issue":"4","key":"1553_CR18","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1111\/j.1600-0765.2011.01366.x","volume":"46","author":"K Hasegawa-Nakamura","year":"2011","unstructured":"Hasegawa-Nakamura K, Tateishi F, Nakamura T, Nakajima Y, Kawamata K, Douchi T, Hatae M, Noguchi K (2011) The possible mechanism of preterm birth associated with periodontopathic Porphyromonas gingivalis. J Periodontal Res 46(4):497\u2013504. doi:\n                    10.1111\/j.1600-0765.2011.01366.x","journal-title":"J Periodontal Res"},{"issue":"5","key":"1553_CR19","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1111\/j.1600-051X.2012.01855.x","volume":"39","author":"F Tateishi","year":"2012","unstructured":"Tateishi F, Hasegawa-Nakamura K, Nakamura T, Oogai Y, Komatsuzawa H, Kawamata K, Douchi T, Hatae M, Noguchi K (2012) Detection of Fusobacterium nucleatum in chorionic tissues of high-risk pregnant women. J Clin Periodontol 39(5):417\u2013424. doi:\n                    10.1111\/j.1600-051X.2012.01855.x","journal-title":"J Clin Periodontol"},{"issue":"5","key":"1553_CR20","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1111\/j.1600-051X.2008.01222.x","volume":"35","author":"C Manau","year":"2008","unstructured":"Manau C, Echeverria A, Agueda A, Guerrero A, Echeverria JJ (2008) Periodontal disease definition may determine the association between periodontitis and pregnancy outcomes. J Clin Periodontol 35(5):385\u2013397. doi:\n                    10.1111\/j.1600-051X.2008.01222.x","journal-title":"J Clin Periodontol"},{"issue":"3","key":"1553_CR21","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1902\/jop.2009.090527","volume":"81","author":"AN Guimaraes","year":"2010","unstructured":"Guimaraes AN, Silva-Mato A, Miranda Cota LO, Siqueira FM, Costa FO (2010) Maternal periodontal disease and preterm or extreme preterm birth: an ordinal logistic regression analysis. J Periodontol 81(3):350\u2013358. doi:\n                    10.1902\/jop.2009.090527","journal-title":"J Periodontol"},{"issue":"6","key":"1553_CR22","doi-asserted-by":"publisher","first-page":"1613","DOI":"10.1016\/0002-9378(94)90412-X","volume":"171","author":"R Romero","year":"1994","unstructured":"Romero R, Baumann P, Gonzalez R, Gomez R, Rittenhouse L, Behnke E, Mitchell MD (1994) Amniotic fluid prostanoid concentrations increase early during the course of spontaneous labor at term. Am J Obstet Gynecol 171(6):1613\u20131620","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"1553_CR23","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1016\/S0029-7844(97)00294-9","volume":"90","author":"PC Greig","year":"1997","unstructured":"Greig PC, Murtha AP, Jimmerson CJ, Herbert WN, Roitman-Johnson B, Allen J (1997) Maternal serum interleukin-6 during pregnancy and during term and preterm labor. Obstet Gynecol 90(3):465\u2013469","journal-title":"Obstet Gynecol"},{"issue":"2 Pt 1","key":"1553_CR24","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/0002-9378(93)90096-2","volume":"169","author":"SL Opsjln","year":"1993","unstructured":"Opsjln SL, Wathen NC, Tingulstad S, Wiedswang G, Sundan A, Waage A, Austgulen R (1993) Tumor necrosis factor, interleukin-1, and interleukin-6 in normal human pregnancy. Am J Obstet Gynecol 169(2 Pt 1):397\u2013404","journal-title":"Am J Obstet Gynecol"},{"issue":"2 Pt 1","key":"1553_CR25","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1097\/AOG.0b013e3181e6dbc0","volume":"116","author":"SQ Wei","year":"2010","unstructured":"Wei SQ, Fraser W, Luo ZC (2010) Inflammatory cytokines and spontaneous preterm birth in asymptomatic women: a systematic review. Obstet Gynecol 116(2 Pt 1):393\u2013401. doi:\n                    10.1097\/AOG.0b013e3181e6dbc0","journal-title":"Obstet Gynecol"},{"issue":"10","key":"1553_CR26","first-page":"877","volume":"41","author":"C Perozini","year":"2010","unstructured":"Perozini C, Chibebe PC, Leao MV, Queiroz Cda S, Pallos D (2010) Gingival crevicular fluid biochemical markers in periodontal disease: a cross-sectional study. Quintessence Int 41(10):877\u2013883","journal-title":"Quintessence Int"},{"issue":"12","key":"1553_CR27","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1111\/j.1600-051X.2010.01624.x","volume":"37","author":"VR Santos","year":"2010","unstructured":"Santos VR, Ribeiro FV, Lima JA, Napimoga MH, Bastos MF, Duarte PM (2010) Cytokine levels in sites of chronic periodontitis of poorly controlled and well-controlled type 2 diabetic subjects. J Clin Periodontol 37(12):1049\u20131058. doi:\n                    10.1111\/j.1600-051X.2010.01624.x","journal-title":"J Clin Periodontol"},{"issue":"1","key":"1553_CR28","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1902\/annals.1998.3.1.233","volume":"3","author":"S Offenbacher","year":"1998","unstructured":"Offenbacher S, Jared HL, O'Reilly PG, Wells SR, Salvi GE, Lawrence HP, Socransky SS, Beck JD (1998) Potential pathogenic mechanisms of periodontitis associated pregnancy complications. Ann Periodontol 3(1):233\u2013250. doi:\n                    10.1902\/annals.1998.3.1.233","journal-title":"Ann Periodontol"},{"issue":"8","key":"1553_CR29","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1111\/j.1600-051X.2007.01105.x","volume":"34","author":"V Canakci","year":"2007","unstructured":"Canakci V, Canakci CF, Yildirim A, Ingec M, Eltas A, Erturk A (2007) Periodontal disease increases the risk of severe pre-eclampsia among pregnant women. J Clin Periodontol 34(8):639\u2013645. doi:\n                    10.1111\/j.1600-051X.2007.01105.x","journal-title":"J Clin Periodontol"},{"issue":"6","key":"1553_CR30","doi-asserted-by":"publisher","first-page":"1453","DOI":"10.1007\/s00784-013-0952-0","volume":"17","author":"P Stadelmann","year":"2013","unstructured":"Stadelmann P, Alessandri R, Eick S, Salvi GE, Surbek D, Sculean A (2013) The potential association between gingival crevicular fluid inflammatory mediators and adverse pregnancy outcomes: a systematic review. Clin Oral Investig 17(6):1453\u20131463. doi:\n                    10.1007\/s00784-013-0952-0","journal-title":"Clin Oral Investig"},{"issue":"9","key":"1553_CR31","doi-asserted-by":"publisher","first-page":"5156","DOI":"10.1128\/IAI.71.9.5156-5162.2003","volume":"71","author":"D Lin","year":"2003","unstructured":"Lin D, Smith MA, Champagne C, Elter J, Beck J, Offenbacher S (2003) Porphyromonas gingivalis infection during pregnancy increases maternal tumor necrosis factor alpha, suppresses maternal interleukin-10, and enhances fetal growth restriction and resorption in mice. Infect Immun 71(9):5156\u20135162","journal-title":"Infect Immun"},{"issue":"3","key":"1553_CR32","doi-asserted-by":"publisher","first-page":"847","DOI":"10.3892\/etm.2013.1222","volume":"6","author":"MK Noh","year":"2013","unstructured":"Noh MK, Jung M, Kim SH, Lee SR, Park KH, Kim DH, Kim HH, Park YG (2013) Assessment of IL-6, IL-8 and TNF-alpha levels in the gingival tissue of patients with periodontitis. Exp Ther Med 6(3):847\u2013851. doi:\n                    10.3892\/etm.2013.1222","journal-title":"Exp Ther Med"},{"issue":"2","key":"1553_CR33","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1084\/jem.20070104","volume":"204","author":"G Trinchieri","year":"2007","unstructured":"Trinchieri G (2007) Interleukin-10 production by effector T cells: Th1 cells show self control. J Exp Med 204(2):239\u2013243. doi:\n                    10.1084\/jem.20070104","journal-title":"J Exp Med"},{"key":"1553_CR34","doi-asserted-by":"crossref","unstructured":"Qi Y, Feng W, Song A, Song H, Yan S, Sun Q, Yang P (2013) Role of serum IL-23\/IL-17 axis in the relationship between periodontitis and coronary heart disease. Int J Periodontics Restorative Dent 33 (2):185-191. doi:10.11607\/prd.1327","DOI":"10.11607\/prd.1327"},{"issue":"7","key":"1553_CR35","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1177\/0022034509339889","volume":"88","author":"H Ohyama","year":"2009","unstructured":"Ohyama H, Kato-Kogoe N, Kuhara A, Nishimura F, Nakasho K, Yamanegi K, Yamada N, Hata M, Yamane J, Terada N (2009) The involvement of IL-23 and the Th17 pathway in periodontitis. J Dent Res 88(7):633\u2013638. doi:\n                    10.1177\/0022034509339889","journal-title":"J Dent Res"}],"updated-by":[{"DOI":"10.1007\/s00784-020-03540-w","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T00:00:00Z","timestamp":1599091200000}}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-015-1553-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00784-015-1553-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-015-1553-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-015-1553-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,3]],"date-time":"2020-09-03T11:04:18Z","timestamp":1599131058000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00784-015-1553-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,7]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,5]]}},"alternative-id":["1553"],"URL":"https:\/\/doi.org\/10.1007\/s00784-015-1553-x","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s00784-020-03540-w","asserted-by":"object"}]},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,7]]},"assertion":[{"value":"10 October 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 July 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 August 2015","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 September 2020","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors are correcting this article because they accidentally included some wrong data in the analysis.","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}}]}}