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Anne Asendorf declares that she has no conflict of interest. Katrin Nickles declares that she has no conflict of interest. Gerhard M. Oremek declares that he has no conflict of interest. Ralf Schubert declares that he has no conflict of interest. Luigi Nibali declares that he has no conflict of interest. Martin Wohlfeil declares that he has no conflict of interest. Peter Eickholz declares that he has no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study conforms to the provisions of the Declaration of Helsinki (as revised in Tokyo 2004) and had been approved by the Institutional Review Board for Human Studies of the Medical Faculty of the Goethe-University Frankfurt\/Main (Application# 188\/06). 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