{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T21:51:37Z","timestamp":1792792297922,"version":"4.5.0"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T00:00:00Z","timestamp":1574726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T00:00:00Z","timestamp":1574726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100002322","name":"CAPES","doi-asserted-by":"crossref","award":["scholarship funded"],"award-info":[{"award-number":["scholarship funded"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1007\/s00784-019-03114-5","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T18:02:36Z","timestamp":1574791356000},"page":"521-532","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":73,"title":["Selective, stepwise, or nonselective removal of carious tissue: which technique offers lower risk for the treatment of dental caries in permanent teeth? A systematic review and meta-analysis"],"prefix":"10.1007","volume":"24","author":[{"given":"Myrna Maria Arcanjo Frota","family":"Barros","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Imaculada","family":"De Queiroz Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Wilker Mustafa Gomes","family":"Muniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8060-8531","authenticated-orcid":false,"given":"Lidiany Karla Azevedo","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,26]]},"reference":[{"key":"3114_CR1","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1038\/sj.ebd.6400948","volume":"14","author":"D Manton","year":"2013","unstructured":"Manton D (2013) Partial caries removal may have advantages but limited evidence on restoration survival. Evid Based Dent 14:74\u201375. https:\/\/doi.org\/10.1038\/sj.ebd.6400948","journal-title":"Evid Based Dent"},{"key":"3114_CR2","doi-asserted-by":"publisher","DOI":"10.1159\/isbn.978-3-318-06369-1","volume-title":"Caries excavation: evolution of treating cavitated carious lesions","author":"F Schwendicke","year":"2018","unstructured":"Schwendicke F, Frencken J, Innes N (2018) Caries excavation: evolution of treating cavitated carious lesions. Karger Medical and Scientific Publishers, Basel"},{"key":"3114_CR3","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1177\/0022034513500792","volume":"92","author":"F Schwendicke","year":"2013","unstructured":"Schwendicke F, Stolpe M, Meyer-Lueckel H, Paris S, Dorfer CE (2013) Cost-effectiveness of one-and two-step incomplete and complete excavations. J Dent Res 92:880\u2013887. https:\/\/doi.org\/10.1177\/0022034513500792","journal-title":"J Dent Res"},{"key":"3114_CR4","doi-asserted-by":"publisher","first-page":"847","DOI":"10.1007\/s00784-016-1832-1","volume":"21","author":"L Casagrande","year":"2017","unstructured":"Casagrande L, Seminario AT, Correa MB, Werle SB, Maltz M, Demarco FF, Araujo FB (2017) Longevity and associated risk factors in adhesive restorations of young permanent teeth after complete and selective caries removal: a retrospective study. Clin Oral Investig 21:847\u2013855. https:\/\/doi.org\/10.1007\/s00784-016-1832-1","journal-title":"Clin Oral Investig"},{"key":"3114_CR5","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1590\/0103-6440201801816","volume":"29","author":"L Bitello-Firmino","year":"2018","unstructured":"Bitello-Firmino L, Soares VK, Dam\u00e9-Teixeira N, Parolo CCF, Maltz M (2018) Microbial load after selective and complete caries removal in permanent molars: a randomized clinical trial. Braz Dent J 29:290\u2013295. https:\/\/doi.org\/10.1590\/0103-6440201801816","journal-title":"Braz Dent J"},{"key":"3114_CR6","doi-asserted-by":"publisher","first-page":"1026","DOI":"10.1177\/0022034512460403","volume":"91","author":"M Maltz","year":"2012","unstructured":"Maltz M, Garcia R, Jardim JJ, Paula LM, Yamaguti PM, Moura MS, Garcia F, Nascimento C, Oliveira A, Mestrinho HD (2012) Randomized trial of partial vs. stepwise caries removal: 3-year follow-up. J Dent Res 91:1026\u20131031. https:\/\/doi.org\/10.1177\/0022034512460403","journal-title":"J Dent Res"},{"key":"3114_CR7","doi-asserted-by":"publisher","first-page":"012119","DOI":"10.1088\/1742-6596\/884\/1\/012119","volume":"884","author":"AR Pratiwi","year":"2017","unstructured":"Pratiwi AR, Meidyawati R, Djauharie N (2017) The effect of MTA application on the affected dentine remineralization after partial caries excavation (in vivo). Journal of Physics: Conf Series 884:012119. https:\/\/doi.org\/10.1088\/1742-6596\/884\/1\/012119","journal-title":"Journal of Physics: Conf Series"},{"key":"3114_CR8","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1002\/j.1875-595X.1997.tb00781.x","volume":"47","author":"T Fusayama","year":"1997","unstructured":"Fusayama T (1997) The process and results of revolution in dental caries treatment. Int Dent J 47:157\u2013166","journal-title":"Int Dent J"},{"key":"3114_CR9","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1177\/0022034516639276","volume":"28","author":"NP Innes","year":"2016","unstructured":"Innes NP, Frencken JE, Bjorndal L, Maltz M, Manton DJ, Ricketts D, Van Landuyt K, Banerjee A, Campus G, Dom\u00e9jean S, Fontana M, Leal S, Lo E, Machiulskiene V, Schulte A, Splieth C, Zandona A, Schwendicke F (2016) Managing carious lesions: consensus recommendations on terminology. Adv Dent Res 28:49\u201357. https:\/\/doi.org\/10.1177\/0022034516639276","journal-title":"Adv Dent Res"},{"key":"3114_CR10","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1159\/000262431","volume":"31","author":"L Bj\u00f8rndal","year":"1997","unstructured":"Bj\u00f8rndal L, Larsen T, Thylstrup A (1997) A clinical and micro-biological study of deep carious lesions during stepwise excavation using long treatment intervals. Caries Res 31:411\u2013417. https:\/\/doi.org\/10.1159\/000262431","journal-title":"Caries Res"},{"key":"3114_CR11","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1159\/000016631","volume":"34","author":"L Bj\u00f8rndal","year":"2000","unstructured":"Bj\u00f8rndal L, Larsen T (2000) Changes in the cultivable flora in deep carious lesions following a stepwise excavation procedure. Caries Res 34:502\u2013508. https:\/\/doi.org\/10.1159\/000016631","journal-title":"Caries Res"},{"key":"3114_CR12","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1016\/j.joen.2008.02.035","volume":"30","author":"L Bj\u00f8rndal","year":"2008","unstructured":"Bj\u00f8rndal L (2008) Indirect pulp therapy and stepwise excavation. Pediat Dent 30:225\u2013229. https:\/\/doi.org\/10.1016\/j.joen.2008.02.035","journal-title":"Pediat Dent"},{"key":"3114_CR13","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1007\/s00784-017-2221-0","volume":"22","author":"M Maltz","year":"2018","unstructured":"Maltz M, Koppe B, Jardim JJ, Alves LS, Paula LM, Yamaguti PM, Almeida JCF, Moura MS, Mestrinho HD (2018) Partial caries removal in deep caries lesions: a 5-year multicenter randomized controlled trial. Clin Oral Investig 22:1337\u20131343. https:\/\/doi.org\/10.1007\/s00784-017-2221-0","journal-title":"Clin Oral Investig"},{"key":"3114_CR14","doi-asserted-by":"publisher","unstructured":"Ricketts D, Lamont T, Innes NP, Kidd E, Clarkson JE (2013) Operative caries management in adults and children. Cochrane Database Syst Rev 3. https:\/\/doi.org\/10.1002\/14651858.CD003808.pub3","DOI":"10.1002\/14651858.CD003808.pub3"},{"key":"3114_CR15","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1080\/00016357.2017.1392602","volume":"76","author":"T Li","year":"2018","unstructured":"Li T, Zhai X, Song F, Zhu H (2018) Selective versus non-selective removal for dental caries: a systematic review and meta-analysis. Acta Odontol Scand 76:135\u2013140. https:\/\/doi.org\/10.1080\/00016357.2017.1392602","journal-title":"Acta Odontol Scand"},{"key":"3114_CR16","doi-asserted-by":"publisher","first-page":"306","DOI":"10.1177\/0022034513477425","volume":"92","author":"F Schwendicke","year":"2013","unstructured":"Schwendicke F, D\u00f6rfer CE, Paris S (2013) Incomplete caries removal: a systematic review and meta-analysis. J Dent Res 92:306\u2013314. https:\/\/doi.org\/10.1177\/0022034513477425","journal-title":"J Dent Res"},{"key":"3114_CR17","doi-asserted-by":"publisher","first-page":"d5928","DOI":"10.1136\/bmj.d5928","volume":"343","author":"JP Higgins","year":"2011","unstructured":"Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, Oxman AD, Savovic J, Schulz KF, Weeks L, Sterne JA (2011) The Cochrane Collaboration\u2019s tool for assessing risk of bias in randomised trials. Bmj 343:d5928. https:\/\/doi.org\/10.1136\/bmj.d5928","journal-title":"Bmj"},{"key":"3114_CR18","unstructured":"Wells G, Shea B, O\u2019Connell D (2012) The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses. Ottawa, ON. http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford_web.ppt. Accessed 12 October 2018"},{"key":"3114_CR19","first-page":"20","volume":"51","author":"M Maltz","year":"2010","unstructured":"Maltz M, Moura MS, Jardim JJ, Marques C, Paula LM, Metrinho HD (2010) Partial caries removal in deep lesions: 19-30 months follow-up study. Rev Fac Odontol 51:20\u201323","journal-title":"Rev Fac Odontol"},{"key":"3114_CR20","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1159\/000344013","volume":"47","author":"M Maltz","year":"2013","unstructured":"Maltz M, Jardim JJ, Mestrinho HD, Yamaguti PM, Podest\u00e1 K, Moura MS, Paula LM (2013) Partial removal of carious dentine: a multicenter randomized controlled trial and 18-month follow-up results. Caries Res 47:103\u2013109. https:\/\/doi.org\/10.1159\/000344013","journal-title":"Caries Res"},{"key":"3114_CR21","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s00784-008-0208-6","volume":"12","author":"AI Orhan","year":"2008","unstructured":"Orhan AI, Oz FT, Ozcelik B, Orhan K (2008) A clinical and microbiological comparative study of deep carious lesion treatment in deciduous and young permanent molars. Clin Oral Investig 12:369\u2013378. https:\/\/doi.org\/10.1007\/s00784-008-0208-6","journal-title":"Clin Oral Investig"},{"key":"3114_CR22","first-page":"347","volume":"32","author":"AI Orhan","year":"2010","unstructured":"Orhan AI, Oz FT, Orhan K (2010) Pulp exposure occurrence and outcomes after 1-or 2-visit indirect pulp therapy vs complete caries removal in primary and permanent molars. Pediatr Dent 32:347\u2013355","journal-title":"Pediatr Dent"},{"key":"3114_CR23","doi-asserted-by":"publisher","first-page":"2161","DOI":"10.4172\/2161-1122.1000162","volume":"3","author":"MPM Rando-Meirelles","year":"2013","unstructured":"Rando-Meirelles MPM, T\u00f4rres LHN, Sousa M (2013) Twenty-four months of follow-up after partial removal of carious dentin: a preliminary study. Dentistry. 3:2161\u20131122.1000162. https:\/\/doi.org\/10.4172\/2161-1122.1000162","journal-title":"Dentistry."},{"key":"3114_CR24","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1186\/s13287-015-0056-7","volume":"6","author":"N Kaukua","year":"2015","unstructured":"Kaukua N, Chen M, Guarnieri P, Dahl M, Lim ML, Yucel-Lindberg T, Sundstrom E, Adameyko I, Mao JJ, Fried K (2015) Molecular differences between stromal cell populations from deciduous and permanent human teeth. Stem Cell Res Ther 6:59. https:\/\/doi.org\/10.1186\/s13287-015-0056-7","journal-title":"Stem Cell Res Ther"},{"key":"3114_CR25","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1111\/iej.13034","volume":"52","author":"WLO da Rosa","year":"2018","unstructured":"da Rosa WLO, Lima VP, Moraes RR, Piva E, da Silva AF (2018) Is a calcium hydroxide liner necessary in the treatment of deep caries lesions? A systematic review and meta-analysis. Int Endod J 52:588\u2013603. https:\/\/doi.org\/10.1111\/iej.13034","journal-title":"Int Endod J"},{"key":"3114_CR26","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1007\/s00784-006-0033-8","volume":"10","author":"EF Oliveira","year":"2006","unstructured":"Oliveira EF, Carminatti G, Fontanella V, Maltz M (2006) The monitoring of deep caries lesions after incomplete dentine caries removal: results after 14\u201318 months. Clin Oral Investig 10:134\u2013139. https:\/\/doi.org\/10.1007\/s00784-006-0033-8","journal-title":"Clin Oral Investig"},{"key":"3114_CR27","doi-asserted-by":"publisher","first-page":"705","DOI":"10.14219\/jada.archive.2008.0252","volume":"139","author":"V Thompson","year":"2008","unstructured":"Thompson V, Craig RG, Curro FA, Green WS, Ship JA (2008) Treatment of deep carious lesions by complete excavation or partial removal: a critical review. J Am Dent Assoc 139:705\u2013712","journal-title":"J Am Dent Assoc"},{"key":"3114_CR28","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1186\/s13012-016-0505-4","volume":"11","author":"F Schwendicke","year":"2016","unstructured":"Schwendicke F, G\u00f6stemeyer G (2016) Understanding dentists\u2019 management of deep carious lesions in permanent teeth: a systematic review and meta-analysis. Implement Sci 11:142\u2013153. https:\/\/doi.org\/10.1186\/s13012-016-0505-4","journal-title":"Implement Sci"},{"key":"3114_CR29","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.jdent.2019.03.009","volume":"84","author":"N Kakudate","year":"2019","unstructured":"Kakudate N, Yokoyama Y, Sumida F, Matsumoto Y, Gordan VV, Gilbert GH (2019) Dentists\u2019 practice patterns of treatment for deep occlusal caries: findings from a dental practice-based research network. J Dent 84:76\u201380","journal-title":"J Dent"},{"key":"3114_CR30","first-page":"197","volume":"55","author":"KT Oen","year":"2007","unstructured":"Oen KT, Thompson VP, Vena D, Caulfield PW, Curro F, Dasanayake A, Ship JA, Lindblad A (2007) Attitudes and expectations of treating deep caries: a PEARL Network survey. Gen Dent 55:197\u2013203","journal-title":"Gen Dent"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-019-03114-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00784-019-03114-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-019-03114-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,24]],"date-time":"2020-11-24T19:12:52Z","timestamp":1606245172000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00784-019-03114-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,26]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["3114"],"URL":"https:\/\/doi.org\/10.1007\/s00784-019-03114-5","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,26]]},"assertion":[{"value":"29 April 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"For this type of study, formal consent is not required.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}