{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T06:26:13Z","timestamp":1781677573866,"version":"3.54.5"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:00Z","timestamp":1604534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T00:00:00Z","timestamp":1604534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005874","name":"Universit\u00e0 degli Studi G. D'Annunzio Chieti Pescara","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005874","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Objectives<\/jats:title>\n                <jats:p>The aim of the present study was to investigate whether peri-implant clinical parameters (modified plaque index (mPI), bleeding and\/or suppuration on probing (B\/SOP)) and local factors (type of prostheses, screw emergence, platform diameter, and abutment angulation) might contribute to the development of additional bone loss and peri-implantitis around dental implants.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Materials and methods<\/jats:title>\n                <jats:p>Two hundred seventy-seven external hex connection implants placed in the posterior maxilla of 124 patients were retrospectively evaluated. They were divided into two groups: physiologic bone loss &lt; 2 mm (PBL) or additional bone loss \u2265 2 mm (ABL). GEE logistic regression was applied to evaluate the influence of type of prostheses (implant-supported single crown (ISSC), fixed partial denture (ISFPD), and full denture (ISFD)) and clinical parameters (mPI and S\/BOP) on bone loss.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Among the 277 implants, 159 (57.4%) presented PBL and 118 (42.6%) presented ABL. Within the ABL group, 20.6% implants were diagnosed with peri-implantitis. mPI significantly correlated with the type of prosthesis and the highest value of mPI (index = 3) was observed in ISFD (23.8%). Moreover, peri-implantitis was more frequently associated with ISFD (32.79%) than ISSC and ISFDP (13.79% and 13.48, respectively)<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>ISFD in the posterior maxilla presented high rates of ABL and showed a higher prevalence of peri-implantitis. None of the local factors seemed to contribute to the development of these conditions. Further investigations are needed to prospectively support the results of the present study.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>Patients rehabilitated with ISFD should be carefully monitored and have more frequent maintenance visits to prevent or control peri-implant bone loss.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-020-03666-x","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T17:03:06Z","timestamp":1604595786000},"page":"3441-3451","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Multivariate analysis of the influence of peri-implant clinical parameters and local factors on radiographic bone loss in the posterior maxilla: a retrospective study on 277 dental implants"],"prefix":"10.1007","volume":"25","author":[{"given":"Mariane B.","family":"Sordi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7652-1660","authenticated-orcid":false,"given":"Vittoria","family":"Perrotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia","family":"Iaculli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keila C. R.","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo S.","family":"Magini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Renvert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano Antonio","family":"Gattone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano","family":"Piattelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco A.","family":"Bianchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,11,5]]},"reference":[{"key":"3666_CR1","first-page":"73,218","volume":"2000","author":"H De Bruyn","year":"2017","unstructured":"De Bruyn H, Christiaens V, Doornewaard R et al (2017) Implant surface roughness and patient factors on long-term peri-implant bone loss. Periodontol 2000:73,218\u201373,227","journal-title":"Periodontol"},{"key":"3666_CR2","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1111\/cid.12457","volume":"19","author":"R Doornewaard","year":"2017","unstructured":"Doornewaard R, Christiaens V, De Bruyn H et al (2017) Long-term effect of surface roughness and patients\u2019 factors on crestal bone loss at dental implants. A systematic review and meta-analysis. Clin Implant Dent Relat Res 19:372\u2013399","journal-title":"Clin Implant Dent Relat Res"},{"issue":"Suppl 1","key":"3666_CR3","doi-asserted-by":"crossref","first-page":"S267","DOI":"10.1002\/JPER.16-0350","volume":"89","author":"F Schwarz","year":"2018","unstructured":"Schwarz F, Derks J, Monje A, Wang HL (2018) Peri-implantitis. J Periodontol 89(Suppl 1):S267\u2013S290","journal-title":"J Periodontol"},{"key":"3666_CR4","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1111\/cid.12017","volume":"14","author":"T Albrektsson","year":"2012","unstructured":"Albrektsson T, Buser D, Chen ST, Cochran D, DeBruyn H, Jemt T, Koka S, Nevins M, Sennerby L, Simion M, Taylor TD, Wennerberg A (2012) Statements from the Estepona consensus meeting on peri-implantitis, February 2-4, 2012. Clin Implant Dent Relat Res 14:781\u2013782","journal-title":"Clin Implant Dent Relat Res"},{"key":"3666_CR5","first-page":"11","volume":"1","author":"T Albrektsson","year":"1986","unstructured":"Albrektsson T, Zarb G, Worthington P, Eriksson AR (1986) The long-term efficacy of currently used dental implants: a review and proposed criteria of success. Int J Oral Maxillofac Implants 1:11\u201325","journal-title":"Int J Oral Maxillofac Implants"},{"key":"3666_CR6","first-page":"415","volume":"44","author":"JGO De Souza","year":"2013","unstructured":"De Souza JGO, Neto AR, Schuldt-Filho G, Dalago HR, de Souza J\u00fanior JM, Bianchini MA (2013) Impact of local and systemic factors on additional peri-implant bone loss. Quintessence Int 44:415\u2013424","journal-title":"Quintessence Int"},{"key":"3666_CR7","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/clr.12636","volume":"26","author":"S Renvert","year":"2015","unstructured":"Renvert S, Quirynen M (2015) Risk indicators for peri-implantitis. A narrative review. Clin Oral Implants Res 26:15\u201344","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR8","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1111\/cid.12427","volume":"18","author":"T Albrektsson","year":"2016","unstructured":"Albrektsson T, Canullo L, Cochran D, De Bruyn H (2016) \u201cPeri-implantitis\u201d: a complication of a foreign body or a man-made \u201cdisease\u201d. Facts and fiction. Clin Implant Dent Relat Res 18:840\u2013849","journal-title":"Clin Implant Dent Relat Res"},{"key":"3666_CR9","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1111\/clr.13264","volume":"29","author":"R Doornewaard","year":"2018","unstructured":"Doornewaard R, Jacquet W, Cosyn J, De Bruyn H (2018) How do peri-implant biologic parameters correspond with implant survival and peri-implantitis? A critical review. Clin Oral Implants Res 29:100\u2013123","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR10","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1111\/clr.12999","volume":"28","author":"G Serino","year":"2017","unstructured":"Serino G, Sato H, Holmes P, Turri A (2017) Intra-surgical vs. radiographic bone level assessments in measuring peri-implant bone loss. Clin Oral Implants Res 28:1396\u20131400","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR11","first-page":"320","volume":"25","author":"T Albrektsson","year":"2012","unstructured":"Albrektsson T, Buser D, Sennerby L (2012) On crestal\/marginal bone loss around dental implants. Int J Prosthodont 25:320\u2013322","journal-title":"Int J Prosthodont"},{"key":"3666_CR12","doi-asserted-by":"crossref","first-page":"297","DOI":"10.11607\/ijp.6577","volume":"33","author":"L Canullo","year":"2020","unstructured":"Canullo L, Pesce P, Patini R, Antonacci D, Tommasato G (2020) What are the effects of different abutment morphologies on peri-implant hard and soft tissue behavior? A Systematic Review and Meta-Analysis. Int J Prosthodont 33:297\u2013306","journal-title":"Int J Prosthodont"},{"key":"3666_CR13","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/clr.12772","volume":"28","author":"HR Dalago","year":"2016","unstructured":"Dalago HR, Schuldt-Filho G, Rodrigues MAP, Renvert S, Bianchini MA (2016) Risk indicators for peri-implantitis. A cross-sectional study with 916 implants. Clin Oral Implants Res 28:144\u2013150","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR14","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1111\/clr.12324","volume":"26","author":"P Galindo-Moreno","year":"2014","unstructured":"Galindo-Moreno P, Le\u00f3n-Cano A, Ortega-Oller I, Monje A, O Valle F, Catena A (2014) Marginal bone loss as success criterion in implant dentistry: beyond 2 mm. Clin Oral Implants Res 26:e28\u2013e34","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR15","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.jdent.2014.12.013","volume":"43","author":"BR Chrcanovic","year":"2015","unstructured":"Chrcanovic BR, Albrektsson T, Wennerberg A (2015) Platform switch and dental implants: a meta-analysis. J Dent 43:629\u2013646","journal-title":"J Dent"},{"issue":"2","key":"3666_CR16","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.joms.2017.08.025","volume":"76","author":"M Tallarico","year":"2018","unstructured":"Tallarico M, Caneva M, Meloni SM, Xhanari E, Covani U, Canullo L (2018) Definitive abutments placed at implant insertion and never removed: is it an effective approach? A systematic review and meta-analysis of randomized controlled trials. J Oral Maxillofac Surg 76(2):316\u2013324","journal-title":"J Oral Maxillofac Surg"},{"key":"3666_CR17","first-page":"603","volume":"28","author":"V Perrotti","year":"2019","unstructured":"Perrotti V, Zhang D, Liang A, Wong J, Quaranta A (2019) The effect of one-abutment at one-time on marginal bone loss around implants placed in healed bone: a systematic review of human studies. Implant Dent 28:603\u2013612","journal-title":"Implant Dent"},{"key":"3666_CR18","first-page":"618","volume":"26","author":"L Canullo","year":"2011","unstructured":"Canullo L, Iannello G, G\u00f6tz W (2011) The influence of individual bone patterns on peri-implant bone loss: preliminary report from a 3-year randomized clinical and histologic trial in patients treated with implants restored with matching-diameter abutments or the platform-switching concept. Int J Oral Maxillofac Implants 26:618\u2013630","journal-title":"Int J Oral Maxillofac Implants"},{"key":"3666_CR19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1365-2842.2006.01689.x","volume":"34","author":"I Turkyilmaz","year":"2007","unstructured":"Turkyilmaz I, T\u00f6z\u00fcm TF, Tumer C (2007) Bone density assessments of oral implant sites using computerized tomography. J Oral Rehabil 34:267\u2013272","journal-title":"J Oral Rehabil"},{"key":"3666_CR20","first-page":"861","volume":"45","author":"G Schuldt-Filho","year":"2014","unstructured":"Schuldt-Filho G, Dalago HR, Souza JG, Stanley K, Jovanovic S, Bianchini MA (2014) Prevalence of peri-implantitis in patients with implant-supported fixed prostheses. Quintessence Int 45:861\u2013868","journal-title":"Quintessence Int"},{"key":"3666_CR21","doi-asserted-by":"crossref","first-page":"2117","DOI":"10.1097\/SCS.0000000000001067","volume":"25","author":"SA Gehrke","year":"2014","unstructured":"Gehrke SA, Silva-Neto UT (2014) Does the time of osseointegration in the maxilla and mandible differ? J Craniofac Surg 25:2117\u20132120","journal-title":"J Craniofac Surg"},{"key":"3666_CR22","doi-asserted-by":"crossref","first-page":"e298","DOI":"10.1111\/cid.12149","volume":"17","author":"S Vervaeke","year":"2015","unstructured":"Vervaeke S, Collaert B, Cosyn J, Deschepper E, De Bruyn H (2015) A multifactorial analysis to identify predictors of implant failure and peri-implant bone loss. Clin Implant Dent Relat Res 17:e298\u2013e307","journal-title":"Clin Implant Dent Relat Res"},{"key":"3666_CR23","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1902\/jop.2005.76.9.1431","volume":"76","author":"D Schwartz-Arad","year":"2005","unstructured":"Schwartz-Arad D, Kidron N, Dolev E (2005) A long-term study of implants supporting overdentures as a model for implant success. J Periodontol 76:1431\u20131435","journal-title":"J Periodontol"},{"key":"3666_CR24","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1590\/1678-775720140055","volume":"22","author":"BB Passoni","year":"2014","unstructured":"Passoni BB, Dalago HR, Schuldt-Filho G et al (2014) Does the number of implants have any relation with peri-implant disease? J Appl Oral Sci 22:403\u2013408","journal-title":"J Appl Oral Sci"},{"issue":"Suppl 15","key":"3666_CR25","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1111\/clr.13103","volume":"29","author":"A Ramanauskaite","year":"2018","unstructured":"Ramanauskaite A, Roccuzzo A, Schwarz F (2018) A systematic review on the influence of the horizontal distance between two adjacent implants inserted in the anterior maxilla on the inter-implant mucosa fill. Clin Oral Implants Res 29(Suppl 15):62\u201370","journal-title":"Clin Oral Implants Res"},{"issue":"Suppl 15","key":"3666_CR26","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/clr.13116","volume":"29","author":"M Roccuzzo","year":"2018","unstructured":"Roccuzzo M, Roccuzzo A, Ramanuskaite A (2018) Papilla height in relation to the distance between bone crest and interproximal contact point at single-tooth implants: a systematic review. Clin Oral Implants Res 29(Suppl 15):50\u201361","journal-title":"Clin Oral Implants Res"},{"issue":"vii","key":"3666_CR27","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.cden.2004.01.001","volume":"48","author":"RS Squier","year":"2004","unstructured":"Squier RS (2004) Jaw relation records for fixed prosthodontics. Dent Clin N Am 48(vii):471\u2013486","journal-title":"Dent Clin N Am"},{"key":"3666_CR28","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1399-302X.1987.tb00298.x","volume":"2","author":"A Mombelli","year":"1987","unstructured":"Mombelli A, van Oosten MA, Schurch-J\u00fanior E, Land NP (1987) The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 2:145\u2013151","journal-title":"Oral Microbiol Immunol"},{"key":"3666_CR29","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1600-0501.2008.01601.x","volume":"20","author":"JA Gerber","year":"2009","unstructured":"Gerber JA, Tan WC, Balmer TE, Salvi GE, Lang NP (2009) Bleeding on probing and pocket probing depth in relation to probing pressure and mucosal health around oral implants. Clin Oral Implants Res 20:75\u201378","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR30","doi-asserted-by":"crossref","first-page":"115","DOI":"10.11607\/jomi.6950","volume":"34","author":"J Cha","year":"2019","unstructured":"Cha J, Wadhwani C, Wang M, Hokett SD, Katancik J (2019) Instrument selection and application used to probe dental implants. Int J Oral Maxillofac Implants 34:115\u2013123","journal-title":"Int J Oral Maxillofac Implants"},{"key":"3666_CR31","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1111\/clr.12181","volume":"25","author":"FG Mangano","year":"2014","unstructured":"Mangano FG, Shibli JA, Sammons RL, Iaculli F, Piattelli A, Mangano C (2014) Short (8-mm) locking-taper implants supporting single crowns in posterior region: a prospective clinical study with 1\u2013to 10-years of follow-up. Clin Oral Implants Res 25:933\u2013940","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR32","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1111\/j.1600-051X.2008.01283.x","volume":"35","author":"J Lindhe","year":"2008","unstructured":"Lindhe J, Meyle J (2008) Peri-implant diseases: consensus report of the Sixth European Workshop on Periodontology. J Clin Periodontol 35:282\u2013285","journal-title":"J Clin Periodontol"},{"key":"3666_CR33","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/0022034516667484","volume":"96","author":"GE Salvi","year":"2016","unstructured":"Salvi GE, Cosgarea R, Sculean A (2016) Prevalence and mechanisms of peri-implant diseases. J Dental Res 96:31\u201337","journal-title":"J Dental Res"},{"issue":"Suppl 20","key":"3666_CR34","doi-asserted-by":"crossref","first-page":"S278","DOI":"10.1111\/jcpe.12956","volume":"45","author":"S Renvert","year":"2018","unstructured":"Renvert S, Persson GR, Pirih FQ, Camargo PM (2018) Peri-implant health, peri-implant mucositis, and peri-implantitis: case definitions and diagnostic considerations. J Clin Periodontol 45(Suppl 20):S278\u2013S285","journal-title":"J Clin Periodontol"},{"key":"3666_CR35","doi-asserted-by":"crossref","first-page":"121","DOI":"10.2307\/2531248","volume":"42","author":"SL Zeger","year":"1986","unstructured":"Zeger SL, Liang KY (1986) Longitudinal data analysis for discrete and continuous outcomes. Biometrics 42:121\u2013130","journal-title":"Biometrics"},{"key":"3666_CR36","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/biomet\/73.1.13","volume":"73","author":"KY Liang","year":"1986","unstructured":"Liang KY, Zeger SL (1986) Longitudinal data analysis using generalized linear models. Biometrika 73:13\u201322","journal-title":"Biometrika"},{"key":"3666_CR37","unstructured":"Carey VJ, Lumley T, and Ripley BD. gee: generalized estimation equation solver, URL http:\/\/CRAN.R-project.org\/package=gee, R package version 4.13-20"},{"key":"3666_CR38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v064.i08","volume":"64","author":"A Touloumis","year":"2015","unstructured":"Touloumis A (2015) R package multgee: a generalized estimating equations solver for multinomial responses. J Stat Softw 64:1\u201314","journal-title":"J Stat Softw"},{"issue":"7","key":"3666_CR39","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1002\/JPER.18-0236","volume":"90","author":"D French","year":"2019","unstructured":"French D, Grandin HM, Ofec R (2019) Retrospective cohort study of 4,591 dental implants: analysis of risk indicators for bone loss and prevalence of peri-implant mucositis and peri-implantitis. J Periodontol 90(7):691\u2013700","journal-title":"J Periodontol"},{"key":"3666_CR40","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.jpor.2015.04.003","volume":"59","author":"K Noda","year":"2015","unstructured":"Noda K, Arakawa H, Kimura-Ono A, Yamazaki S, Hara ES, Sonoyama W, Maekawa K, Okura K, Shintani A, Matsuka Y, Kuboki T (2015) A longitudinal retrospective study of the analysis of the risk factors of implant failure by the application of generalized estimating equations. J Prosthodont Res 59:178\u2013184","journal-title":"J Prosthodont Res"},{"key":"3666_CR41","first-page":"75","volume":"8","author":"IK Konstantinidis","year":"2015","unstructured":"Konstantinidis IK, Kotsakis GA, Gerdes S, Walter MH (2015) Cross-sectional study on the prevalence and risk indicators of peri-implant diseases. Eur J Oral Implantol 8:75\u201388","journal-title":"Eur J Oral Implantol"},{"key":"3666_CR42","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/clr.13411","volume":"30","author":"L Francetti","year":"2019","unstructured":"Francetti L, Cavalli N, Taschieri S, Corbella S (2019) Ten years follow-up retrospective study on implant survival rates and prevalence of peri-implantitis in implant-supported full-arch rehabilitations. Clin Oral Implants Res 30:252\u2013260","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR43","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/jcpe.12334","volume":"42","author":"J Derks","year":"2015","unstructured":"Derks J, Tomasi C (2015) Peri-implant health and disease. A systematic review of current epidemiology. J Clin Periodontol 42:158\u2013171","journal-title":"J Clin Periodontol"},{"key":"3666_CR44","doi-asserted-by":"crossref","first-page":"S286","DOI":"10.1111\/jcpe.12957","volume":"45","author":"T Berglundh","year":"2018","unstructured":"Berglundh T, Armitage G, Araujo MG, Avila-Ortiz G, Blanco J, Camargo PM, Chen S, Cochran D, Derks J, Figuero E, H\u00e4mmerle CHF, Heitz-Mayfield LJA, Huynh-Ba G, Iacono V, Koo KT, Lambert F, McCauley L, Quirynen M, Renvert S, Salvi GE, Schwarz F, Tarnow D, Tomasi C, Wang HL, Zitzmann N (2018) Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Clin Periodontol 45:S286\u2013S291","journal-title":"J Clin Periodontol"},{"key":"3666_CR45","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1111\/j.1708-8208.2012.00453.x","volume":"14","author":"P-O \u00d6stman","year":"2012","unstructured":"\u00d6stman P-O, Hellman M, Sennerby L (2012) Ten years later. Results from a prospective single-centre clinical study on 121 oxidized (TiUniteTM) Br\u00e5nemark implants in 46 patients. Clin Implant Dent Relat Res 14:852\u2013860","journal-title":"Clin Implant Dent Relat Res"},{"key":"3666_CR46","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/clr.13152","volume":"29","author":"A Ramanauskaite","year":"2018","unstructured":"Ramanauskaite A, Becker K, Schwarz F (2018) Clinical characteristics of peri-implant mucositis and peri-implantitis. Clin Oral Implants Res 29:551\u2013556","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR47","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1111\/clr.12974","volume":"28","author":"P Rammelsberg","year":"2017","unstructured":"Rammelsberg P, Lorenzo-Bermejo J, Kappel S (2017) Effect of prosthetic restoration on implant survival and success. Clin Oral Implants Res 28:1296\u20131302","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR48","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/jcpe.12240","volume":"41","author":"F Schwarz","year":"2014","unstructured":"Schwarz F, Mihatovic I, Golubovich V, Eick S, Iglhaut T, Becker J (2014) Experimental peri-implant mucositis at different implant surfaces. J Clin Periodontol 41:513\u2013520","journal-title":"J Clin Periodontol"},{"key":"3666_CR49","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/jcpe.12346","volume":"42","author":"S Renvert","year":"2015","unstructured":"Renvert S, Polyzois I (2015) Risk indicators for peri-implant mucositis: a systematic literature review. J Clin Periodontol 42:172\u2013186","journal-title":"J Clin Periodontol"},{"key":"3666_CR50","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1111\/clr.12738","volume":"27","author":"L Canullo","year":"2016","unstructured":"Canullo L, Tallarico M, Radovanovic S, Delibasic B, Covani U, Rakic M (2016) Distinguishing predictive profiles for patient-based risk assessment and diagnostics of plaque induced, surgically and prosthetically triggered peri-implantitis. Clin Oral Implants Res 27:1243\u20131250","journal-title":"Clin Oral Implants Res"},{"key":"3666_CR51","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1600-0501.2009.01867.x","volume":"21","author":"L Canullo","year":"2010","unstructured":"Canullo L, Fedele GR, Iannello G, Jepsen S (2010) Platform switching and marginal bone-level alterations: the results of a randomized controlled trial. Clin Oral Implants Res 21:115\u2013121","journal-title":"Clin Oral Implants Res"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-020-03666-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-020-03666-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-020-03666-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T09:19:29Z","timestamp":1621502369000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-020-03666-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,5]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["3666"],"URL":"https:\/\/doi.org\/10.1007\/s00784-020-03666-x","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,5]]},"assertion":[{"value":"3 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 October 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee (approval number: 1.430.035) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}