{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:53:01Z","timestamp":1792176781923,"version":"4.4.0"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T00:00:00Z","timestamp":1609977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T00:00:00Z","timestamp":1609977600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1007\/s00784-020-03702-w","type":"journal-article","created":{"date-parts":[[2021,1,7]],"date-time":"2021-01-07T21:14:59Z","timestamp":1610054099000},"page":"3747-3755","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":59,"title":["Efficacy of platelet-rich fibrin compared with triamcinolone acetonide as injective therapy in the treatment of symptomatic oral lichen planus: a pilot study"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6528-2681","authenticated-orcid":false,"given":"Francesco","family":"Bennardo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Liborio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0701-2675","authenticated-orcid":false,"given":"Selene","family":"Barone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9557-3586","authenticated-orcid":false,"given":"Alessandro","family":"Antonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8228-8356","authenticated-orcid":false,"given":"Caterina","family":"Buffone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8701-5018","authenticated-orcid":false,"given":"Leonzio","family":"Fortunato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5091-6979","authenticated-orcid":false,"given":"Amerigo","family":"Giudice","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,7]]},"reference":[{"issue":"4","key":"3702_CR1","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1054\/bjom.2000.0555","volume":"38","author":"N Mollaoglu","year":"2000","unstructured":"Mollaoglu N (2000) Oral lichen planus: a review. Brit J Oral Maxillofacial Surg 38(4):370\u2013377. https:\/\/doi.org\/10.1054\/bjom.2000.0555","journal-title":"Brit J Oral Maxillofacial Surg"},{"issue":"2","key":"3702_CR2","doi-asserted-by":"publisher","first-page":"89","DOI":"10.2334\/josnusd.49.89","volume":"49","author":"SB Ismail","year":"2007","unstructured":"Ismail SB, Kumar SKS, Zain RB (2007) Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation. J Oral Sci 49(2):89\u2013106. https:\/\/doi.org\/10.2334\/josnusd.49.89","journal-title":"J Oral Sci"},{"key":"3702_CR3","doi-asserted-by":"publisher","unstructured":"Thongprasom K, Carrozzo M, Furness S, Lodi G (2011) Interventions for treating oral lichen planus. Cochrane Database Syst Rev 6;(7):CD001168. https:\/\/doi.org\/10.1002\/14651858.cd001168.pub2","DOI":"10.1002\/14651858.cd001168.pub2"},{"issue":"8","key":"3702_CR4","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1007\/s00403-016-1667-2","volume":"308","author":"MS Alrashdan","year":"2016","unstructured":"Alrashdan MS, Cirillo N, McCullough M (2016) Oral lichen planus: a literature review and update. Arch Dermatol Res 308(8):539\u2013551. https:\/\/doi.org\/10.1007\/s00403-016-1667-2","journal-title":"Arch Dermatol Res"},{"key":"3702_CR5","doi-asserted-by":"publisher","unstructured":"Lodi G, Manfredi M, Mercadante V, Murphy R, Carrozzo M (2020) Interventions for treating oral lichen planus: corticosteroid therapies. Cochrane Database Syst Rev 28;2(2):CD001168. https:\/\/doi.org\/10.1002\/14651858.cd001168.pub3","DOI":"10.1002\/14651858.cd001168.pub3"},{"key":"3702_CR6","doi-asserted-by":"publisher","unstructured":"Giudice A, Liborio F, Averta F, Barone S, Fortunato L (2019) Oral lichenoid reaction: an uncommon side effect of rituximab. Case Rep Dent 6;2019:3154856. https:\/\/doi.org\/10.1155\/2019\/3154856","DOI":"10.1155\/2019\/3154856"},{"key":"3702_CR7","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1080\/09546630410030720","volume":"15","author":"J Dissemond","year":"2004","unstructured":"Dissemond J (2004) Oral lichen planus: an overview. J Dermatolog Treat 15:136\u2013140. https:\/\/doi.org\/10.1080\/09546630410030720","journal-title":"J Dermatolog Treat"},{"issue":"6","key":"3702_CR8","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1034\/j.1600-0714.2003.00173.x","volume":"32","author":"M Carbone","year":"2003","unstructured":"Carbone M, Goss E, Carrozzo M, Castellano S, Conrotto D, Broccoletti R, Gandolfo S (2003) Systemic and topical corticosteroid treatment of oral lichen planus: a comparative study with long-term follow-up. J Oral Pathol Med 32(6):323\u2013329. https:\/\/doi.org\/10.1034\/j.1600-0714.2003.00173.x","journal-title":"J Oral Pathol Med"},{"key":"3702_CR9","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1016\/j.tripleo.2004.06.076","volume":"100","author":"G Lodi","year":"2005","unstructured":"Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K (2005) Current controversies in oral lichen planus: report of an international consensus meeting. Part 2. Clinical management and malignant transformation. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:164\u2013178. https:\/\/doi.org\/10.1016\/j.tripleo.2004.06.076","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"3702_CR10","doi-asserted-by":"publisher","first-page":"947","DOI":"10.1007\/s00784-018-2519-6","volume":"23","author":"OM Ezzatt","year":"2019","unstructured":"Ezzatt OM, Helmy IM (2019) Topical pimecrolimus versus betamethasone for oral lichen planus: a randomized clinical trial. Clin Oral Invest 23:947\u2013956. https:\/\/doi.org\/10.1007\/s00784-018-2519-6","journal-title":"Clin Oral Invest"},{"key":"3702_CR11","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1007\/s00784-017-2112-4","volume":"22","author":"R Zaslansky","year":"2018","unstructured":"Zaslansky R, Schramm C, Stein C, G\u00fcthoff C, Schmidt-Westhausen AM (2018) Topical application of morphine for wound healing and analgesia in patients with oral lichen planus: a randomized, double-blind, placebo-controlled study. Clin Oral Invest 22:305\u2013311. https:\/\/doi.org\/10.1007\/s00784-017-2112-4","journal-title":"Clin Oral Invest"},{"issue":"6","key":"3702_CR12","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1111\/j.1600-0714.2006.00441.x","volume":"35","author":"J Xia","year":"2006","unstructured":"Xia J, Li C, Hong Y, Yang L, Huang Y, Cheng B (2006) Short-term clinical evaluation of intralesional triamcinolone acetonide injection for ulcerative oral lichen planus. J Oral Pathol Med 35(6):327\u2013331. https:\/\/doi.org\/10.1111\/j.1600-0714.2006.00441.x","journal-title":"J Oral Pathol Med"},{"issue":"3","key":"3702_CR13","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1177\/0194599812473237","volume":"148","author":"YC Lee","year":"2013","unstructured":"Lee YC, Shin SY, Kim SW, Eun YG (2013) Intralesional injection versus mouth rinse of triamcinolone acetonide in oral lichen planus: a randomized controlled study. Otolaryngol Head Neck Surg 148(3):443\u2013449. https:\/\/doi.org\/10.1177\/0194599812473237","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"5","key":"3702_CR14","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1016\/j.oooo.2019.07.024","volume":"128","author":"PJ Fantozzi","year":"2019","unstructured":"Fantozzi PJ, Treister N, Shekar R, Woo SB, Villa A (2019) Intralesional triamcinolone acetonide therapy for inflammatory oral ulcers. Oral Surg Oral Med Oral Pathol Oral Radiol 128(5):485\u2013490. https:\/\/doi.org\/10.1016\/j.oooo.2019.07.024","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"3702_CR15","doi-asserted-by":"crossref","unstructured":"Casabona F, Priano, Vallerino V, Cogliandro A, Lavagnino G (2010) New surgical approach to lichen sclerosus of the vulva: the role of adipose-derived mesenchymal cells and platelet-rich plasma in tissue regeneration. Plast Reconstr Surg 126(4):210e-211e. 10.1097\/prs.0b013e3181ea9386","DOI":"10.1097\/PRS.0b013e3181ea9386"},{"key":"3702_CR16","doi-asserted-by":"crossref","unstructured":"Casabona F, Gambelli I, Casabona F, Santi P, Santori G, Baldelli I (2017) Autologous platelet rich plasma (PRP) in chronic penile lichen sclerosus: the impact on tissue repair and patient quality of life. Int Urol Nephrol 49:573\u2013580. (a)","DOI":"10.1007\/s11255-017-1523-0"},{"issue":"4","key":"3702_CR17","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1111\/dth.12343","volume":"29","author":"\u017d Bolan\u010da","year":"2016","unstructured":"Bolan\u010da \u017d, Goren A, Getaldi\u0107-\u0160varc B, Vu\u010di\u0107 M (2016) \u0160itum M (2016) Platelet-rich plasma as a novel treatment for lichen planopillaris. Dermatol Ther 29(4):233\u2013235. https:\/\/doi.org\/10.1111\/dth.12343","journal-title":"Dermatol Ther"},{"issue":"3","key":"3702_CR18","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1007\/s40257-017-0277-x","volume":"18","author":"L Pi\u00f1as","year":"2017","unstructured":"Pi\u00f1as L, Alkhraisat MH, Fern\u00e1ndez RS, Anitua E (2017) Biological therapy of refractory ulcerative oral lichen planus with plasma rich in growth factors. Am J Clin Dermatol 18(3):429\u2013433. https:\/\/doi.org\/10.1007\/s40257-017-0277-x","journal-title":"Am J Clin Dermatol"},{"key":"3702_CR19","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.aanat.2017.12.006","volume":"216","author":"L Pi\u00f1as","year":"2018","unstructured":"Pi\u00f1as L, Alkhraisat MH, Su\u00e1rez-Fern\u00e1ndez R, Anitua E (2018) Biomolecules in the treatment of lichen planus refractory to corticosteroid therapy: clinical and histopathological assessment. Ann Anat 216:159\u2013163. https:\/\/doi.org\/10.1016\/j.aanat.2017.12.006","journal-title":"Ann Anat"},{"key":"3702_CR20","doi-asserted-by":"publisher","unstructured":"Bennardo F, Bennardo L, Del Duca E et al (2020) Autologous platelet-rich fibrin injections in the management of facial cutaneous sinus tracts secondary to medication-related osteonecrosis of the jaw. Dermatol Ther:e13334. https:\/\/doi.org\/10.1111\/dth.13334","DOI":"10.1111\/dth.13334"},{"key":"3702_CR21","doi-asserted-by":"publisher","first-page":"j2835","DOI":"10.1136\/bmj.j2835","volume":"357","author":"N Pandis","year":"2017","unstructured":"Pandis N, Chung B, Scherer RW, Elbourne D, Altman DG (2017) CONSORT 2010 statement: extension checklist for reporting within person randomised trials. Bmj 357:j2835. https:\/\/doi.org\/10.1136\/bmj.j2835","journal-title":"Bmj"},{"key":"3702_CR22","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1016\/0030-4220(78)90382-1","volume":"46","author":"IR Kramer","year":"1978","unstructured":"Kramer IR, Lucas RB, Pindborg FF, Sobin LH (1978) Definition of leukoplakia and related lesions: an aid to studies on oral pre-cancer. Oral Surg Oral Med Oral Pathol 46:568\u2013569","journal-title":"Oral Surg Oral Med Oral Pathol"},{"issue":"7","key":"3702_CR23","doi-asserted-by":"publisher","first-page":"1460","DOI":"10.1016\/j.joms.2018.01.012","volume":"76","author":"L Fortunato","year":"2018","unstructured":"Fortunato L, Barone S, Bennardo F, Giudice A (2018) Management of facial pyoderma gangrenosum using platelet-rich fibrin: a technical report. J Oral Maxillofac Surg 76(7):1460\u20131463. https:\/\/doi.org\/10.1016\/j.joms.2018.01.012","journal-title":"J Oral Maxillofac Surg"},{"key":"3702_CR24","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1007\/s00784-018-2555-2","volume":"23","author":"HA Varela","year":"2019","unstructured":"Varela HA, Souza JCM, Nascimento RM, Ara\u00fajo RF Jr, Vasconcelos RC, Cavalcante RS, Guedes PM, Ara\u00fajo AA (2019) Injectable platelet rich fibrin: cell content, morphological, and protein characterization. Clin Oral Invest 23:1309\u20131318. https:\/\/doi.org\/10.1007\/s00784-018-2555-2","journal-title":"Clin Oral Invest"},{"key":"3702_CR25","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1111\/j.1600-0714.1992.tb00974.x","volume":"21","author":"K Thongprasom","year":"1992","unstructured":"Thongprasom K, Luangjarmekorn L, Sererat T, Taweesap W (1992) Relative efficacy of fluocinolone acetonide compared with triamcinolone acetonide in treatment of oral lichen planus. J Oral Pathol Med 21:456\u2013458. https:\/\/doi.org\/10.1111\/j.1600-0714.1992.tb00974.x","journal-title":"J Oral Pathol Med"},{"key":"3702_CR26","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/0304-3959(76)90113-5","volume":"2","author":"J Scott","year":"1976","unstructured":"Scott J, Huskisson E (1976) Graphic representation of pain. Pain 2:175\u2013184","journal-title":"Pain"},{"issue":"4","key":"3702_CR27","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1111\/j.1834-7819.2002.tb00540.x","volume":"47","author":"PB Sugerman","year":"2002","unstructured":"Sugerman PB, Savage NW (2002) Oral lichen planus: causes, diagnosis and management. Aust Dent J 47(4):290\u2013297. https:\/\/doi.org\/10.1111\/j.1834-7819.2002.tb00540.x","journal-title":"Aust Dent J"},{"issue":"2","key":"3702_CR28","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1001\/jamadermatol.2019.3797","volume":"156","author":"C Li","year":"2020","unstructured":"Li C, Tang X, Zheng X, Ge S, Wen H, Lin X, Chen Z, Lu L (2020) Global prevalence and incidence estimates of oral lichen planus: a systematic review and meta-analysis. JAMA Dermatol 156(2):172\u2013181. https:\/\/doi.org\/10.1001\/jamadermatol.2019.3797","journal-title":"JAMA Dermatol"},{"issue":"12","key":"3702_CR29","doi-asserted-by":"publisher","first-page":"4441","DOI":"10.1007\/s00784-019-02892-2","volume":"23","author":"ML Zucoloto","year":"2019","unstructured":"Zucoloto ML, Shibakura MEW, Pavanin JV, Garcia FT, da Silva Santos PS, Maciel AP, de Barros Gallo C, Souza NV, Innocentini LMAR, Humberto JSM, Motta ACF (2019) Severity of oral lichen planus and oral lichenoid lesions is associated with anxiety. Clin Oral Invest 23(12):4441\u20134448. https:\/\/doi.org\/10.1007\/s00784-019-02892-2","journal-title":"Clin Oral Invest"},{"issue":"9","key":"3702_CR30","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1016\/j.archoralbio.2013.04.004","volume":"58","author":"MR Payeras","year":"2013","unstructured":"Payeras MR, Cherubini K, Figueiredo MA, Salum FG (2013) Oral lichen planus: focus on etiopathogenesis. Arch Oral Biol 58(9):1057\u20131069. https:\/\/doi.org\/10.1016\/j.archoralbio.2013.04.004","journal-title":"Arch Oral Biol"},{"issue":"8","key":"3702_CR31","first-page":"494","volume":"68","author":"PC Edwards","year":"2002","unstructured":"Edwards PC, Kelsch R (2002) Oral lichen planus: clinical presentation and management. J Can Dent Assoc 68(8):494\u2013499","journal-title":"J Can Dent Assoc"},{"key":"3702_CR32","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1001\/archpedi.1983.02140370086033","volume":"137","author":"G Stoppoloni","year":"1983","unstructured":"Stoppoloni G, Prisco F, Santinelli R, Sicuranza G, Giordano C (1983) Potential hazards of topical steroid therapy. Am J Dis Child 137:1130\u20131131. https:\/\/doi.org\/10.1001\/archpedi.1983.02140370086033","journal-title":"Am J Dis Child"},{"issue":"34","key":"3702_CR33","doi-asserted-by":"publisher","first-page":"5470","DOI":"10.2174\/138161212803307617","volume":"18","author":"J Bagan","year":"2012","unstructured":"Bagan J, Compilato D, Paderni C et al (2012) Topical therapies for oral lichen planus management and their efficacy: a narrative review. Curr Pharm Des 18(34):5470\u20135480. https:\/\/doi.org\/10.2174\/138161212803307617","journal-title":"Curr Pharm Des"},{"issue":"1","key":"3702_CR34","first-page":"77","volume":"12","author":"A Giudice","year":"2019","unstructured":"Giudice A, Esposito M, Bennardo F, Brancaccio Y, Buti J, Fortunato L (2019) Dental extractions for patients on oral antiplatelet: a within-person randomised controlled trial comparing haemostatic plugs, advanced-platelet-rich fibrin (A-PRF+) plugs, leukocyte-and platelet-rich fibrin (L-PRF) plugs and suturing alone. Eur J Oral Implantol 12(1):77\u201387","journal-title":"Eur J Oral Implantol"},{"key":"3702_CR35","doi-asserted-by":"publisher","first-page":"4373","DOI":"10.1007\/s00784-020-03303-7","volume":"24","author":"M Fujioka-Kobayashi","year":"2020","unstructured":"Fujioka-Kobayashi M, Katagiri H, Kono M, Schaller B, Zhang Y, Sculean A, Miron RJ (2020) Improved growth factor delivery and cellular activity using concentrated platelet-rich fibrin (C-PRF) when compared with traditional injectable (i-PRF) protocols. Clin Oral Invest 24:4373\u20134383. https:\/\/doi.org\/10.1007\/s00784-020-03303-7","journal-title":"Clin Oral Invest"},{"issue":"3","key":"3702_CR36","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1016\/j.jcms.2020.01.014","volume":"48","author":"L Fortunato","year":"2020","unstructured":"Fortunato L, Bennardo F, Buffone C, Giudice A (2020) Is the application of platelet concentrates effective in the prevention and treatment of medication-related osteonecrosis of the jaw? A systematic review. J Craniomaxillofac Surg 48(3):268\u2013285. https:\/\/doi.org\/10.1016\/j.jcms.2020.01.014","journal-title":"J Craniomaxillofac Surg"},{"issue":"5","key":"3702_CR37","doi-asserted-by":"publisher","DOI":"10.1111\/dth.13062","volume":"32","author":"R Gasparro","year":"2019","unstructured":"Gasparro R, Adamo D, Masucci M, Sammartino G, Mignogna MD (2019) Use of injectable platelet-rich fibrin in the treatment of plasma cell mucositis of the oral cavity refractory to corticosteroid therapy: a case report. Dermatol Ther 32(5):e13062. https:\/\/doi.org\/10.1111\/dth.13062","journal-title":"Dermatol Ther"},{"key":"3702_CR38","doi-asserted-by":"publisher","first-page":"2619","DOI":"10.1007\/s00784-017-2063-9","volume":"8","author":"RJ Miron","year":"2017","unstructured":"Miron RJ, Fujioka-Kobayashi M, Hernandez M, Kandalam U, Zhang Y, Ghanaati S, Choukroun J (2017) Injectable platelet rich fibrin (i-PRF): opportunities in regenerative dentistry? Clin Oral Investig 8:2619\u20132627. https:\/\/doi.org\/10.1007\/s00784-017-2063-9","journal-title":"Clin Oral Investig"},{"issue":"1","key":"3702_CR39","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1080\/09537104.2017.1293807","volume":"29","author":"X Wang","year":"2017","unstructured":"Wang X, Zhang Y, Choukroun J, Ghanaati S, Richard J, Miron RJ (2017) Effects of an injectable platelet-rich fibrin on osteoblast behavior and bone tissue formation in comparison to platelet-rich plasma. Platelets 29(1):48\u201355. https:\/\/doi.org\/10.1080\/09537104.2017.1293807","journal-title":"Platelets"},{"issue":"8","key":"3702_CR40","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1111\/jop.12425","volume":"45","author":"R Ni Riordain","year":"2016","unstructured":"Ni Riordain R, Hodgson PS, Fedele S (2016) Validity and reliability of the chronic oral mucosal diseases questionnaire in a UK population. J Oral Pathol Med 45(8):613\u2013616. https:\/\/doi.org\/10.1111\/jop.12425","journal-title":"J Oral Pathol Med"},{"issue":"5","key":"3702_CR41","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1111\/odi.12821","volume":"24","author":"PG Arduino","year":"2018","unstructured":"Arduino PG, Campolongo MG, Sciannameo V, Conrotto D, Gambino A, Cabras M, Ricceri F, Carossa S, Broccoletti R, Carbone M (2018) Randomized, placebo-controlled, double-blind trial of clobetasol propionate 0.05% in the treatment of oral lichen planus. Oral Dis 24(5):772\u2013777. https:\/\/doi.org\/10.1111\/odi.12821","journal-title":"Oral Dis"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-020-03702-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-020-03702-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-020-03702-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T09:29:35Z","timestamp":1621502975000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-020-03702-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,7]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["3702"],"URL":"https:\/\/doi.org\/10.1007\/s00784-020-03702-w","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,7]]},"assertion":[{"value":"17 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The ethical approval was obtained by the Ethical Review Board of Central Calabria (Prot. No. 23\/2019).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Research involving human participants and\/or animals"}},{"value":"All patients enrolled for the study signed an informed consent.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}