{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T20:36:00Z","timestamp":1790022960478,"version":"4.0.1"},"reference-count":41,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2021,1,28]],"date-time":"2021-01-28T00:00:00Z","timestamp":1611792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,1,28]],"date-time":"2021-01-28T00:00:00Z","timestamp":1611792000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100001862","name":"Svenska Forskningsr\u00e5det Formas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001862","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008408","name":"H\u00f6gskolan Kristianstad","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008408","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin Oral Invest"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The present study assessed if individuals \u2265\u200960\u00a0years of age with periodontitis are more likely to develop stroke or ischemic heart diseases, or at a higher risk of death for 17\u00a0years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and methods<\/jats:title>\n                    <jats:p>At baseline individuals \u2265\u200960 received a dental examination including a panoramic radiograph. Periodontitis was defined as having \u2265\u200930% sites with \u2265\u20095-mm distance from the cementoenamel junction to the marginal bone level. Medical records were annually reviewed from 2001 to 2018. Findings from the medical records identifying an ICD-10 code of stroke and ischemic heart diseases or death were registered.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Associations between periodontitis and incidence of ischemic heart disease were found in this 17-year follow-up study in all individuals 60\u201393\u00a0years (HR: 1.5, CI: 1.1\u20132.1,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.017), in women (HR: 2.1, CI: 1.3\u20133.4,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002), and in individuals 78\u201396\u00a0years (HR: 1.7, CI: 1.0\u20132.6,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.033). Periodontitis was associated with mortality in all individuals (HR: 1.4, CI: 1.2\u20131.8,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002), specifically in men (HR: 1.5, CI: 1.1\u20131.9,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006) or in ages 60\u201372\u00a0years (HR: 2.2, CI: 1.5\u20133.2,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000). Periodontitis was more prevalent among men (OR: 1.8, CI: 1.3\u20132.4,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.000).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Individuals with periodontitis have an increased risk for future events of ischemic heart diseases and death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance<\/jats:title>\n                    <jats:p>Improving periodontal health in older individuals may reduce overall mortality and ischemic heart diseases. Both dental and medical professionals should be aware of the associations and ultimately cooperate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00784-020-03739-x","type":"journal-article","created":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T19:04:06Z","timestamp":1611774246000},"page":"4085-4095","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Periodontitis related to cardiovascular events and mortality: a long-time longitudinal study"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8092-665X","authenticated-orcid":false,"given":"Viveca Wallin","family":"Bengtsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3620-5978","authenticated-orcid":false,"given":"G\u00f6sta Rutger","family":"Persson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4312-2246","authenticated-orcid":false,"given":"Johan Sanmartin","family":"Berglund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0992-2362","authenticated-orcid":false,"given":"Stefan","family":"Renvert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,1,28]]},"reference":[{"issue":"62","key":"3739_CR1","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1111\/j.1600-0757.2012.00450.x","volume":"2000","author":"PM Bartold","year":"2013","unstructured":"Bartold PM, van Dyke TE (2013) Periodontitis: a host-mediated disrupture of microbial homeostasis unlearning learned concepts. Periodontology 2000(62):203\u2013217. https:\/\/doi.org\/10.1111\/j.1600-0757.2012.00450.x","journal-title":"Periodontology"},{"key":"3739_CR2","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1177\/0022034514552491","volume":"93","author":"NJ Kassebaum","year":"2014","unstructured":"Kassebaum NJ, Bernab\u00e9 E, Dahiya M, Bhandari B, Murray CJ, Marcenes W (2014) Global burden of severe periodontitis in 1990\u20132010: a systematic review and meta-regression. J Dent Res 93:1045\u20131053. https:\/\/doi.org\/10.1177\/0022034514552491","journal-title":"J Dent Res"},{"key":"3739_CR3","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1177\/0022034512457373","volume":"91","author":"PI Eke","year":"2012","unstructured":"Eke PI, Dye BA, Wei L, Thornton-Evans GO, Genco RJ (2012) CDC Periodontal Disease Surveillance workgroup: James Beck, Gordon Douglass Roy Page. Prevalence of periodontitis in adults in the United States: 2009 and 2010. J Dent Res 91:914\u2013920","journal-title":"J Dent Res"},{"issue":"72","key":"3739_CR4","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1111\/prd.12145","volume":"2000","author":"PI Eke","year":"2016","unstructured":"Eke PI, Wei L, Borgnakke WS, Thornton-Evans G, Zhang X, Lu H, McGuire LC, Genco RJ (2016) Periodontitis prevalence in adults, \u2265 65 years of age, in the USA. Periodontology 2000(72):76\u201395. https:\/\/doi.org\/10.1111\/prd.12145","journal-title":"Periodontology"},{"issue":"347\u2013356","key":"3739_CR5","first-page":"10.111\/1440","volume":"40","author":"AM Waters","year":"2013","unstructured":"Waters AM, Trinh L, Chau T, Bourchier M, Moon L (2013) Latest statistics on cardiovascular disease in Australia. Clin Exp Pharmacol Physiol 40(347\u2013356):10.111\/1440\u201311681.12079","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"3739_CR6","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1001\/jamacardio.2018.0385","volume":"3","author":"GA Roth","year":"2018","unstructured":"Roth GA, Johnson CO, Abate KH et al (2018) Global burden of cardiovascular diseases collaboration, the burden of cardiovascular diseases among US states, 1990-2016. JAMA Cardiol 3:375\u2013389. https:\/\/doi.org\/10.1001\/jamacardio.2018.0385","journal-title":"JAMA Cardiol"},{"key":"3739_CR7","doi-asserted-by":"publisher","first-page":"2120","DOI":"10.1161\/01.STR.0000085086.50957.22","volume":"34","author":"M Desvarieux","year":"2003","unstructured":"Desvarieux M, Demmer RT, Rundek T, Boden-Albala B, Jacobs DR Jr, Papapanou PN, Sacco RL (2003) Oral Infections and Vascular Disease Epidemiology Study (INVEST). Relationship between periodontal disease, tooth loss, and carotid artery plaque: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). Stroke 34:2120\u20132125","journal-title":"Stroke"},{"key":"3739_CR8","doi-asserted-by":"publisher","first-page":"2520","DOI":"10.1161\/CIR.0b013e31825719f3","volume":"125","author":"PB Lockhart","year":"2012","unstructured":"Lockhart PB, Bolger AF, Papapanou PN et al (2012) American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, Council on Epidemiology and Prevention, Council on Peripheral Vascular Disease, and Council on Clinical Cardiology. Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association? A scientific statement from the American Heart Association. Circulation 125:2520\u20132544. https:\/\/doi.org\/10.1161\/CIR.0b013e31825719f3","journal-title":"Circulation"},{"key":"3739_CR9","doi-asserted-by":"publisher","first-page":"1314","DOI":"10.1007\/s00380-017-1003-6","volume":"32","author":"N Aoyama","year":"2017","unstructured":"Aoyama N, Suzuki JI, Kobayashi N, Hanatani T, Ashigaki N, Yoshida A, Shiheido Y, Sato H, Kumagai H, Ikeda Y, Akazawa H, Komuro I, Izumi Y, Isobe M (2017) Periodontitis deteriorates peripheral arterial disease in Japanese population via enhanced systemic inflammation. Heart Vessel 32:1314\u20131319. https:\/\/doi.org\/10.1007\/s00380-017-1003-6","journal-title":"Heart Vessel"},{"key":"3739_CR10","doi-asserted-by":"publisher","first-page":"1195","DOI":"10.1161\/01.STR.0000165916.90593.cb","volume":"36","author":"PO S\u00f6der","year":"2005","unstructured":"S\u00f6der PO, S\u00f6der B, Nowak J, Jogestrand T (2005) Early carotid atherosclerosis in subjects with periodontal diseases. Stroke 36:1195\u20132000","journal-title":"Stroke"},{"key":"3739_CR11","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1902\/annals.2003.8.1.38","volume":"8","author":"FA Scannapieco","year":"2003","unstructured":"Scannapieco FA, Bush RB, Paju S (2003) Associations between periodontal disease and risk for atherosclerosis, cardiovascular disease, and stroke. A systematic review. Annuals of Periodontology 8:38\u201353. https:\/\/doi.org\/10.1902\/annals.2003.8.1.38","journal-title":"Annuals of Periodontology"},{"key":"3739_CR12","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1111\/j.1600-051X.2008.01278.x","volume":"35","author":"D Kinane","year":"2008","unstructured":"Kinane D, Bouchard P, Group E of European Workshop on Periodontology (2008) J Clin Periodontol 35:333\u2013337. https:\/\/doi.org\/10.1111\/j.1600-051X.2008.01278.x","journal-title":"J Clin Periodontol"},{"key":"3739_CR13","doi-asserted-by":"publisher","first-page":"271","DOI":"10.1111\/prd.12007","volume":"62","author":"MP Cullinan","year":"2013","unstructured":"Cullinan MP, Seymour GJ (2013) Periodontal diseases and health: consensus report of the Sixth European Workshop on Periodontology. Periodontology 2000 62:271\u2013286. https:\/\/doi.org\/10.1111\/prd.12007","journal-title":"Periodontology 2000"},{"key":"3739_CR14","doi-asserted-by":"publisher","first-page":"S30","DOI":"10.1111\/jcpe.12079","volume":"40","author":"L Reyes","year":"2013","unstructured":"Reyes L, Herrera D, Kozarov E, Rold\u00e1n S, Progulske-Fox AJ (2013) Periodontal bacterial invasion and infection: contribution to atherosclerotic pathology. Clinical Periodontology 40:S30\u2013S50. https:\/\/doi.org\/10.1111\/jcpe.12079","journal-title":"Clinical Periodontology"},{"key":"3739_CR15","doi-asserted-by":"publisher","first-page":"S51","DOI":"10.1111\/jcpe.12060","volume":"40","author":"HA Schenkein","year":"2013","unstructured":"Schenkein HA, Loos BG (2013) Inflammatory mechanisms linking periodontal diseases to cardiovascular diseases. Jorunal of Clinical Periodontology 40:S51\u2013S69. https:\/\/doi.org\/10.1111\/jcpe.12060","journal-title":"Jorunal of Clinical Periodontology"},{"issue":"4 Suppl","key":"3739_CR16","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1902\/jop.2013.1340019","volume":"84","author":"MS Tonetti","year":"2013","unstructured":"Tonetti MS, Van Dyke TE (2013) Working group 1 of the joint EFP\/AAP workshop. Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP\/AAP Workshop on Periodontitis and Systemic Diseases. J Periodontol 84(4 Suppl):24\u201329. https:\/\/doi.org\/10.1902\/jop.2013.1340019","journal-title":"J Periodontol"},{"issue":"1155\u201361","key":"3739_CR17","doi-asserted-by":"publisher","first-page":"e66","DOI":"10.1111\/ene","volume":"21","author":"A Lafon","year":"2014","unstructured":"Lafon A, Pereira B, Dufour T et al (2014) Periodontal disease and stroke: a meta-analysis of cohort studies. Eur J Neurol 21(1155\u201361):e66\u2013e67. https:\/\/doi.org\/10.1111\/ene","journal-title":"Eur J Neurol"},{"key":"3739_CR18","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1161\/01.STR.0000110789.20526.9D","volume":"35","author":"AJ Grau","year":"2004","unstructured":"Grau AJ, Becher H, Ziegler CM, Lichy C, Buggle F, Kaiser C, Lutz R, B\u00fcltmann S, Preusch M, D\u00f6rfer CE (2004) Periodontal disease as a risk factor for ischemic stroke. Stroke 35:496\u2013501. https:\/\/doi.org\/10.1161\/01.STR.0000110789.20526.9D","journal-title":"Stroke"},{"issue":"23","key":"3739_CR19","doi-asserted-by":"publisher","first-page":"2108","DOI":"10.1016\/j.ehj.2003.10.007","volume":"24","author":"GR Persson","year":"2003","unstructured":"Persson GR, Ohlsson O, Pettersson T (2003) Chronic periodontitis, a significant relationship with acute myocardial infarction. Eur Heart J 24(23):2108\u20132115. https:\/\/doi.org\/10.1016\/j.ehj.2003.10.007","journal-title":"Eur Heart J"},{"key":"3739_CR20","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1161\/CIRCULATIONAHA.115.020324","volume":"133","author":"L Ryd\u00e9n","year":"2016","unstructured":"Ryd\u00e9n L, Buhlin K, Ekstrand E et al (2016) Periodontitis increases the risk of a first myocardial infarction: a report from the PAROKRANK study. Circulation 133:576\u2013583. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.115.020324","journal-title":"Circulation"},{"key":"3739_CR21","doi-asserted-by":"publisher","first-page":"S70","DOI":"10.1111\/jcpe.12062","volume":"14","author":"T Dietrich","year":"2013","unstructured":"Dietrich T, Sharma P, Walter C (2013) The epidemiological evidence behind the association between periodontitis and incident atherosclerotic cardiovascular disease. J Clin Periodontol 14:S70\u2013S84. https:\/\/doi.org\/10.1111\/jcpe.12062","journal-title":"J Clin Periodontol"},{"key":"3739_CR22","doi-asserted-by":"publisher","first-page":"994","DOI":"10.1093\/eurheartj\/ehi819","volume":"27","author":"M Stramba-Badiale","year":"2006","unstructured":"Stramba-Badiale M, Fox KM, Priori SG, Collins P, Daly C, Graham I, Jonsson B, Schenck-Gustafsson K, Tendera M (2006) Cardiovascular diseases in women: a statement from the policy conference of the European Society of Cardiology. Eur Heart J 27:994\u20131005","journal-title":"Eur Heart J"},{"key":"3739_CR23","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.amjcard.2016.05.036","volume":"118","author":"GM Hansen","year":"2016","unstructured":"Hansen GM, Egeberg A, Holmstrup P, Hansen PR (2016) Relation of periodontitis to risk of cardiovascular and all-cause mortality (from a Danish Nationwide Cohort Study). Am J Cardiol 118:489\u2013493. https:\/\/doi.org\/10.1016\/j.amjcard.2016.05.036","journal-title":"Am J Cardiol"},{"key":"3739_CR24","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1177\/0022034518814829","volume":"98","author":"HJ Lee","year":"2019","unstructured":"Lee HJ, Choi EK, Park JB, Han KD, Oh S (2019) Tooth loss predicts myocardial infarction, heart failure, stroke, and death. J Dent Res 98:164\u2013170. https:\/\/doi.org\/10.1177\/0022034518814829","journal-title":"J Dent Res"},{"key":"3739_CR25","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1016\/j.ijcard.2013.08.132","volume":"169","author":"HW Park","year":"2013","unstructured":"Park HW, Yoon CH, Kang SH, Choi DJ, Kim HS, Cho MC, Kim YJ, Chae SC, Yoon JH, Gwon HC, Ahn YK, Jeong MH, KAMIR\/KorMI Registry (2013) Early- and late-term clinical outcome and their predictors in patients with ST-segment elevation myocardial infarction and non-ST segment elevation myocardial infarction. Int J Cardiol 169:254\u2013261","journal-title":"Int J Cardiol"},{"key":"3739_CR26","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1111\/jcpe.12611","volume":"43","author":"S Reichert","year":"2016","unstructured":"Reichert S, Schulz S, Benten AC, Lutze A, Seifert T, Schlitt M, Werdan K, Hofmann B, Wienke A, Schaller HG, Schlitt A (2016) Periodontal conditions and incidence of new cardiovascular events among patients with coronary vascular disease. J Clin Periodontol 43:918\u2013925. https:\/\/doi.org\/10.1111\/jcpe.12611","journal-title":"J Clin Periodontol"},{"key":"3739_CR27","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1111\/j.1600-0765.2006.00957.x","volume":"42","author":"B S\u00f6der","year":"2007","unstructured":"S\u00f6der B, Jin LJ, Klinge B, S\u00f6der PO (2007) Periodontitis and premature death: a 16-year longitudinal study in a Swedish urban population. J Periodontal Res 42:361\u2013366","journal-title":"J Periodontal Res"},{"key":"3739_CR28","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1177\/0022034515586352","volume":"94","author":"JM Liljestrand","year":"2015","unstructured":"Liljestrand JM, Havulinna AS, Paju S, M\u00e4nnist\u00f6 S, Salomaa V, Pussinen PJ (2015) Missing teeth predict incident cardiovascular events, diabetes, and death. J Dent Res 94:1055\u20131062. https:\/\/doi.org\/10.1177\/0022034515586352","journal-title":"J Dent Res"},{"key":"3739_CR29","doi-asserted-by":"publisher","unstructured":"GBD 2017 Risk Factor Collaborators (2018) Global, regional, and national comparative risk assessment of 84 behavioural, environmental and occupational, and metabolic risks or clusters of risks for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 392:1923\u20131994. https:\/\/doi.org\/10.1016\/S0140-6736(18)32225-6 Erratum in: Lancet 2019; 393:132. Lancet 2019;393:e44","DOI":"10.1016\/S0140-6736(18)32225-6"},{"key":"3739_CR30","doi-asserted-by":"publisher","first-page":"531","DOI":"10.3389\/fphar.2019.00531","volume":"10","author":"EPC van der Vorst","year":"2019","unstructured":"van der Vorst EPC, Peters LJF, M\u00fcller M, Gencer S, Yan Y, Weber C, D\u00f6ring Y (2019) G-protein coupled receptor targeting on myeloid cells in atherosclerosis. Front Pharmacology 10:531. https:\/\/doi.org\/10.3389\/fphar.2019.00531","journal-title":"Front Pharmacology"},{"key":"3739_CR31","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1016\/j.atherosclerosis.2017.05.009","volume":"262","author":"A Holmlund","year":"2017","unstructured":"Holmlund A, Lampa E, Lind L (2017) Oral health and cardiovascular disease risk in a cohort of periodontitis patients. Atherosclerosis 262:101\u2013106. https:\/\/doi.org\/10.1016\/j.atherosclerosis.2017.05.009","journal-title":"Atherosclerosis"},{"key":"3739_CR32","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1902\/jop.2011.110100","volume":"83","author":"A Holmlund","year":"2012","unstructured":"Holmlund A, Lind L (2012) Number of teeth is related to atherosclerotic plaque in the carotid arteries in an elderly population. J Periodontol 83:287\u2013291. https:\/\/doi.org\/10.1902\/jop.2011.110100","journal-title":"J Periodontol"},{"key":"3739_CR33","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.sdj.2014.11.002","volume":"35","author":"ZS Natto","year":"2014","unstructured":"Natto ZS, Aladmawy M, Alasqah M, Papas A (2014) Factors contributing to tooth loss among the elderly: a cross-sectional study. Singap Dent J 35:17\u201322. https:\/\/doi.org\/10.1016\/j.sdj.2014.11.002","journal-title":"Singap Dent J"},{"issue":"Suppl 1","key":"3739_CR34","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1002\/JPER.17-0721","volume":"89","author":"PN Papapanou","year":"2018","unstructured":"Papapanou PN, Sanz M, Buduneli NS, Dietrich T, Feres M, Fine DH, Flemmig TF, Garcia R, Giannobile WV, Graziani F, Greenwell H, Herrera D, Kao RT, Kebschull M, Kinane DF, Kirkwood KL, Kocher T, Kornman KS, Kumar PS, Loos BG, Machtei E, Meng H, Mombelli A, Needleman I, Offenbacher S, Seymour GJ, Teles R, Tonetti MS (2018) Periodontitis: consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol 89(Suppl 1):173\u2013182. https:\/\/doi.org\/10.1002\/JPER.17-0721","journal-title":"J Periodontol"},{"issue":"Suppl 1","key":"3739_CR35","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1002\/JPER.17-0062","volume":"89","author":"I Needleman","year":"2018","unstructured":"Needleman I, Garcia R, Gkranias N (2018) Mean annual attachment, bone level, and tooth loss: a systematic review. J Periodontol 89(Suppl 1):120\u2013139. https:\/\/doi.org\/10.1002\/JPER.17-0062","journal-title":"J Periodontol"},{"key":"3739_CR36","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1902\/jop.2000.71.10.1583","volume":"71","author":"MS Reddy","year":"2000","unstructured":"Reddy MS, Geurs NC, Jeffcoat RL, Proskin H, Jeffcoat MK (2000) Periodontal disease progression. J Periodontol 71:1583\u20131590","journal-title":"J Periodontol"},{"key":"3739_CR37","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1111\/j.1600-051X.1998.tb02501.x","volume":"25","author":"RE Persson","year":"1998","unstructured":"Persson RE, Hollender LG, Persson GR (1998) Assessment of alveolar bone levels from intraoral radiographs in subjects between ages 15 and 94 years seeking dental care. J Clin Periodontol 25:647\u2013654","journal-title":"J Clin Periodontol"},{"issue":"Suppl. 1","key":"3739_CR38","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1002\/JPER.17-0670","volume":"89","author":"M Billings","year":"2018","unstructured":"Billings M, Holtfreter B, Papapanou PN, Mitnik GL, Kocher T, Dye BA (2018) Age-dependent distribution of periodontitis in two countries: findings from NHANES 2009 to 2014 and SHIP-TREND 2008 to 2012. J Periodontol 89(Suppl. 1):140\u2013158. https:\/\/doi.org\/10.1002\/JPER.17-0670","journal-title":"J Periodontol"},{"issue":"8","key":"3739_CR39","doi-asserted-by":"publisher","first-page":"661","DOI":"10.1111\/j.1600-0765.1997.tb00576.x","volume":"32","author":"EE Machtei","year":"1997","unstructured":"Machtei EE, Hausmann E, Grossi SG, Dunford R, Genco RJ (1997) The relationship between radiographic and clinical changes in the periodontium. J Periodontal Res 32(8):661\u2013666","journal-title":"J Periodontal Res"},{"key":"3739_CR40","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1111\/j.1600-051X.1984.tb01331.x","volume":"11","author":"JM Goodson","year":"1984","unstructured":"Goodson JM, Haffajee AD, Socransky SS (1984) The relationship between attachment level loss and alveolar bone loss. Journal of Clinal Periodontology 11:348\u2013359","journal-title":"Journal of Clinal Periodontology"},{"key":"3739_CR41","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1016\/S0140-6736(18)32203-7","volume":"10","author":"GBD","year":"2017","unstructured":"GBD (2017) Causes of Death Collaborators (2018) Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet 10:1736\u20131788. https:\/\/doi.org\/10.1016\/S0140-6736(18)32203-7","journal-title":"Lancet"}],"container-title":["Clinical Oral Investigations"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-020-03739-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00784-020-03739-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00784-020-03739-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T05:30:08Z","timestamp":1621488608000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00784-020-03739-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,28]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["3739"],"URL":"https:\/\/doi.org\/10.1007\/s00784-020-03739-x","relation":{},"ISSN":["1432-6981","1436-3771"],"issn-type":[{"value":"1432-6981","type":"print"},{"value":"1436-3771","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1,28]]},"assertion":[{"value":"17 September 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 January 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in the study, involving human participants, were following the ethical standards of the regional research ethics committee and with the 1964 Helsinki declaration and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All individuals included in the study signed an informed consent.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The sponsors had no role in any aspect of the study design or reporting of findings.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}