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Clinical parameters (probing depth, PD; clinical attachment level, CAL; gingival recession, REC) had been assessed at pre-surgery and 12 months post-surgery.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Complete wound closure was observed in 70% and 80% of defects treated with SFA and SFA+EMD, respectively. Treatments resulted in a significant PD reduction of 3.1\u00b11.0 mm (<jats:italic>p<\/jats:italic>=0.005). In SFA+EMD group, 100% of closed pockets was obtained, while 90% of closed pockets was observed in SFA group. Both treatments resulted in a significant CAL gain of 2.1\u00b10.9 mm and 1.9\u00b11.7 mm in SFA and SFA+EMD group, respectively (<jats:italic>p<\/jats:italic>= 0.465). In both groups, REC significantly increased 1.0\u00b11.1 mm in SFA group and 1.1\u00b11.1 mm in SFA+EMD group (<jats:italic>p<\/jats:italic>= 0.722).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Within their limits, the findings of present study suggest that SFA may represent a valuable option for the surgical treatment of SDs associated with deep pockets. EMD did not result in a significant clinical benefit to the procedure.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical relevance<\/jats:title>\n                <jats:p>SFA may represent a valuable option in obtaining pocket closure when treating SDs associated with deep residual pockets.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00784-021-03941-5","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T06:24:01Z","timestamp":1618467841000},"page":"6385-6392","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Single flap approach with or without enamel matrix derivative in the treatment of severe supraosseous defects: a retrospective study"],"prefix":"10.1007","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2332-7332","authenticated-orcid":false,"given":"Anna","family":"Simonelli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Minenna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonardo","family":"Trombelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Farina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,4,14]]},"reference":[{"key":"3941_CR1","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1034\/j.1600-0757.2000.2220102","volume":"22","author":"PN Papapanou","year":"2000","unstructured":"Papapanou PN, Tonetti MS (2000) Diagnosis and epidemiology of periodontal osseous lesions. 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Dr. Luigi Minenna declares that he has no conflict of interest. Prof. Leonardo Tombelli received honoraria for lectures and courses from Straumann AG. Prof. Roberto Farina declares that he has no conflict of interest.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}