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OHRQoL (Oral Health Impact Profile-14 (OHIP-14)); number of decayed, missing, and filled teeth (DMFT); denture use; periodontal inflamed surface area (PISA); xerostomia (xerostomia inventory (XI)); and possible TMD (-pain) diagnoses were recorded. The groups were compared on these variables. Subsequently, backward multiple regression analyses were performed for the ERA and at-risk groups, with OHRQoL as the dependent variable and gender, age, DMFT, denture use, PISA, XI, non-painful TMD, and TMD pain as independent variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At-risk individuals had higher XI scores (U\u2009=\u2009789.5, z\u2009=\u2009-3.181, p\u2009=\u20090.001, r\u2009=\u2009-0.32) and higher prevalence of TMD pain (p\u2009=\u20090.046, OR\u2009=\u20094.57; 95% CI 0.92\u201322.73) than healthy controls and higher OHIP-14 scores than the ERA group (U\u2009=\u2009894.5, z\u2009=\u2009-2.418, p\u2009=\u20090.016, r\u2009=\u2009-0.24), while no difference in OHIP-14 was found between the control group and both other groups. For ERA patients, OHRQoL was associated with PISA and TMD pain (R\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.498, p\u2009&lt;\u20090.001). For at-risk individuals, OHRQoL was associated with XI score (R\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.410, p\u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Alertness of health professionals to TMD pain and periodontal inflammation in ERA patients and to xerostomia and TMD pain in at-risk individuals is recommended.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical relevance<\/jats:title>\n                    <jats:p>The results of this study address orofacial aspects that require attention of health professionals in the timeframe around RA onset.<\/jats:p>\n                    <jats:p>\n                      <jats:bold>Trial registration:<\/jats:bold>\n                      Dutch National Trial Register (NTR, NTR6362)\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00784-021-04034-z","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T09:03:26Z","timestamp":1626685406000},"page":"555-563","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Oral health-related quality of life in patients with early rheumatoid arthritis is associated with periodontal inflammation and painful temporomandibular disorders: a cross-sectional study"],"prefix":"10.1007","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2288-6450","authenticated-orcid":false,"given":"Johanna M.","family":"Kroese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine M. 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